+

WO2008139122A3 - Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation, et leurs utilisations - Google Patents

Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation, et leurs utilisations Download PDF

Info

Publication number
WO2008139122A3
WO2008139122A3 PCT/FR2008/050724 FR2008050724W WO2008139122A3 WO 2008139122 A3 WO2008139122 A3 WO 2008139122A3 FR 2008050724 W FR2008050724 W FR 2008050724W WO 2008139122 A3 WO2008139122 A3 WO 2008139122A3
Authority
WO
WIPO (PCT)
Prior art keywords
topical
pharmaceutical
same
preparation methods
cosmetic preparations
Prior art date
Application number
PCT/FR2008/050724
Other languages
English (en)
Other versions
WO2008139122A2 (fr
Inventor
Marc Moutet
Jean-Claude Yadan
Original Assignee
Galderma Res & Dev
Marc Moutet
Jean-Claude Yadan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galderma Res & Dev, Marc Moutet, Jean-Claude Yadan filed Critical Galderma Res & Dev
Priority to CA002686505A priority Critical patent/CA2686505A1/fr
Priority to EP08788212A priority patent/EP2155212A2/fr
Priority to US12/599,674 priority patent/US20100323985A1/en
Publication of WO2008139122A2 publication Critical patent/WO2008139122A2/fr
Publication of WO2008139122A3 publication Critical patent/WO2008139122A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63—Steroids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/88—Two- or multipart kits
    • A61K2800/884—Sequential application
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/91—Injection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne une association d'acide hyaluronique et d'au moins un inhibiteur de la dégradation de l'acide hyaluronique pour une utilisation en particulier en dermatologie humaine ou en chirurgie réparatrice.
PCT/FR2008/050724 2007-05-11 2008-04-22 Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation, et leurs utilisations WO2008139122A2 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CA002686505A CA2686505A1 (fr) 2007-05-11 2008-04-22 Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation, et leurs utilisations
EP08788212A EP2155212A2 (fr) 2007-05-11 2008-04-22 Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation, et leurs utilisations
US12/599,674 US20100323985A1 (en) 2007-05-11 2008-04-22 Pharmaceutical or cosmetic preparations for topical and/or parenteral application, preparation methods thereof and use of same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0755023 2007-05-11
FR0755023 2007-05-11

Publications (2)

Publication Number Publication Date
WO2008139122A2 WO2008139122A2 (fr) 2008-11-20
WO2008139122A3 true WO2008139122A3 (fr) 2009-02-05

Family

ID=38777678

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2008/050724 WO2008139122A2 (fr) 2007-05-11 2008-04-22 Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation, et leurs utilisations

Country Status (4)

Country Link
US (1) US20100323985A1 (fr)
EP (1) EP2155212A2 (fr)
CA (1) CA2686505A1 (fr)
WO (1) WO2008139122A2 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8946192B2 (en) 2010-01-13 2015-02-03 Allergan, Inc. Heat stable hyaluronic acid compositions for dermatological use
US9480775B2 (en) 2010-03-22 2016-11-01 Allergan, Inc. Polysaccharide and protein-polysaccharide cross-linked hydrogels for soft tissue augmentation
US11844878B2 (en) 2011-09-06 2023-12-19 Allergan, Inc. Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2861734B1 (fr) 2003-04-10 2006-04-14 Corneal Ind Reticulation de polysaccharides de faible et forte masse moleculaire; preparation d'hydrogels monophasiques injectables; polysaccharides et hydrogels obtenus
TR201901431T4 (tr) 2007-11-16 2019-02-21 Aclaris Therapeutics Inc Purpura tedavisi için bileşimler ve yöntemler.
US8394782B2 (en) 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having increased longevity
US8357795B2 (en) 2008-08-04 2013-01-22 Allergan, Inc. Hyaluronic acid-based gels including lidocaine
WO2010028025A1 (fr) 2008-09-02 2010-03-11 Gurtner Geoffrey C Fils d'acide hyaluronique et/ou dérivés de ceux-ci, procédés de fabrication de ceux-ci et utilisations de ceux-ci
FR2948286B1 (fr) 2009-07-27 2011-08-26 Jean-Noel Thorel Composition injectable associant un agent de comblement et un milieu de croissance des fibroblastes
US9114188B2 (en) 2010-01-13 2015-08-25 Allergan, Industrie, S.A.S. Stable hydrogel compositions including additives
US8586562B2 (en) 2010-03-12 2013-11-19 Allergan Industrie, Sas Fluid compositions for improving skin conditions
US8883139B2 (en) 2010-08-19 2014-11-11 Allergan Inc. Compositions and soft tissue replacement methods
US8889123B2 (en) 2010-08-19 2014-11-18 Allergan, Inc. Compositions and soft tissue replacement methods
US9005605B2 (en) 2010-08-19 2015-04-14 Allergan, Inc. Compositions and soft tissue replacement methods
EP3536307B1 (fr) 2011-06-03 2021-10-20 ALLERGAN Industrie, SAS Compositions de remplissage dermique comprenant des antioxydants
US9393263B2 (en) 2011-06-03 2016-07-19 Allergan, Inc. Dermal filler compositions including antioxidants
US9408797B2 (en) 2011-06-03 2016-08-09 Allergan, Inc. Dermal filler compositions for fine line treatment
US20130096081A1 (en) 2011-06-03 2013-04-18 Allergan, Inc. Dermal filler compositions
US20130244943A1 (en) 2011-09-06 2013-09-19 Allergan, Inc. Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
US9822223B2 (en) 2012-06-15 2017-11-21 Merz Pharma Gmbh & Co. Kgaa Method of preparing a composition based on hyaluronic acid
US10111904B2 (en) * 2013-01-09 2018-10-30 Berlock Aps Micron-sized gold, kit comprising said gold and its use as a non-toxic immune suppressor
WO2016051219A1 (fr) 2014-09-30 2016-04-07 Allergan Industrie, Sas Compositions d'hydrogel stables pourvues d'additifs
WO2016128783A1 (fr) 2015-02-09 2016-08-18 Allergan Industrie Sas Compositions et méthodes pour améliorer l'apparence de la peau
WO2017001057A1 (fr) 2015-06-30 2017-01-05 Merz Pharma Gmbh & Co. Kgaa Procédé de préparation de composition à base d'acide hyaluronique
DE102016208567A1 (de) * 2016-05-19 2017-11-23 Heraeus Medical Gmbh Polymerlösung zur Viscosupplementation
US20210322458A1 (en) * 2020-04-20 2021-10-21 Gregg Tobin Methods and compositions for treatment of burns, joint pain, and fungal infections

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04305517A (ja) * 1991-03-30 1992-10-28 Kanebo Ltd 養毛化粧料
JP2000191498A (ja) * 1998-12-24 2000-07-11 Maruzen Pharmaceut Co Ltd コラ―ゲン産生促進剤および皮膚外用剤
KR20010001290A (ko) * 1999-06-03 2001-01-05 서경배 피부 주름의 개선 및 생성 억제 효과를 갖는 외용제 조성물
WO2003000191A2 (fr) * 2001-06-25 2003-01-03 Depuy Composition comprenant des glycosaminoglycanes et des inhibiteurs d'hyaluronidase destinee au traitement d'articulations arthritiques
WO2004000242A1 (fr) * 2002-06-25 2003-12-31 Cosmeceutic Solutions Pty Ltd Compositions cosmetiques topiques
JP2004083484A (ja) * 2002-08-27 2004-03-18 Nobel Kagaku Kogyo Kk 皮膚外用剤
WO2006020994A2 (fr) * 2004-08-13 2006-02-23 Angiotech International Ag Compositions et methodes utilisant de l'acide hyaluronique
WO2006087392A2 (fr) * 2005-02-21 2006-08-24 Relivia S.R.L. Substances, compositions et methodes de traitement d'alopecie
US20060247183A1 (en) * 2002-04-09 2006-11-02 Sinclair Pharmaceuticals Ltd. Compositions and methods for the treatment of inflammatory conditions of mucosae, skin and the eye
WO2007074288A1 (fr) * 2005-12-21 2007-07-05 Galderma Research & Development Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation, et leurs utilisations

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4879114A (en) * 1985-12-20 1989-11-07 Angio-Medical Corporation Lipids from omentum and methods for cosmetic use
US5371089A (en) * 1987-02-26 1994-12-06 Senetek, Plc Method and composition for ameliorating the adverse effects of aging
US5977088A (en) * 1991-07-03 1999-11-02 Hyal Pharmaceutical Corporation Formulations containing hyaluronic acid
WO1994001074A1 (fr) * 1992-07-13 1994-01-20 Shiseido Company, Ltd. Composition de preparation dermatologique
US5723139A (en) * 1996-09-27 1998-03-03 Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. Skin care compositions containing a polycyclic triterpene carboxylic acid and a retinoid
US5861149A (en) * 1997-06-04 1999-01-19 Polyheal Ltd. Methods for wound treatment
WO2000038647A1 (fr) * 1998-12-23 2000-07-06 Esparma Gmbh Agents pour proteger la peau, contenant un melange de fragments produit par hydrolyse a partir d'acide hyaluronique

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04305517A (ja) * 1991-03-30 1992-10-28 Kanebo Ltd 養毛化粧料
JP2000191498A (ja) * 1998-12-24 2000-07-11 Maruzen Pharmaceut Co Ltd コラ―ゲン産生促進剤および皮膚外用剤
KR20010001290A (ko) * 1999-06-03 2001-01-05 서경배 피부 주름의 개선 및 생성 억제 효과를 갖는 외용제 조성물
WO2003000191A2 (fr) * 2001-06-25 2003-01-03 Depuy Composition comprenant des glycosaminoglycanes et des inhibiteurs d'hyaluronidase destinee au traitement d'articulations arthritiques
US20060247183A1 (en) * 2002-04-09 2006-11-02 Sinclair Pharmaceuticals Ltd. Compositions and methods for the treatment of inflammatory conditions of mucosae, skin and the eye
WO2004000242A1 (fr) * 2002-06-25 2003-12-31 Cosmeceutic Solutions Pty Ltd Compositions cosmetiques topiques
JP2004083484A (ja) * 2002-08-27 2004-03-18 Nobel Kagaku Kogyo Kk 皮膚外用剤
WO2006020994A2 (fr) * 2004-08-13 2006-02-23 Angiotech International Ag Compositions et methodes utilisant de l'acide hyaluronique
WO2006087392A2 (fr) * 2005-02-21 2006-08-24 Relivia S.R.L. Substances, compositions et methodes de traitement d'alopecie
WO2007074288A1 (fr) * 2005-12-21 2007-07-05 Galderma Research & Development Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation, et leurs utilisations

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
"Agent for dermal application to whiten skin - comprises L-ascorbic acid and acetylated hyaluronic acid", DERWENT, 1998, XP002199812 *
DATABASE WPI Week 199250, Derwent World Patents Index; AN 1992-410112, XP002463318 *
DATABASE WPI Week 200050, Derwent World Patents Index; AN 2000-545821, XP002463317 *
DATABASE WPI Week 200146, Derwent World Patents Index; AN 2001-430654, XP002463320 *
DATABASE WPI Week 200424, Derwent World Patents Index; AN 2004-252691, XP002463319 *
FURUYA T ET AL: "BIOCHEMICAL CHARACTERIZATION OF GLYCYRRHIZIN AS AN EFFECTIVE INHIBITOR FOR HYALURONIDASE FROM BOVINE TESTIS", BIOLOGICAL & PHARMACEUTICAL BULLETIN (OF JAPAN), PHARMACEUTICAL SOCIETY OF JAPAN, TOKYO, JP, vol. 20, no. 9, September 1997 (1997-09-01), pages 973 - 977, XP001207776, ISSN: 0918-6158 *
GIRISH ET AL: "The magic glue hyaluronan and its eraser hyaluronidase: A biological overview", LIFE SCIENCES, PERGAMON PRESS, OXFORD, GB, vol. 80, no. 21, 20 April 2007 (2007-04-20), pages 1921 - 1943, XP022036977, ISSN: 0024-3205 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8946192B2 (en) 2010-01-13 2015-02-03 Allergan, Inc. Heat stable hyaluronic acid compositions for dermatological use
US9480775B2 (en) 2010-03-22 2016-11-01 Allergan, Inc. Polysaccharide and protein-polysaccharide cross-linked hydrogels for soft tissue augmentation
US11844878B2 (en) 2011-09-06 2023-12-19 Allergan, Inc. Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation

Also Published As

Publication number Publication date
EP2155212A2 (fr) 2010-02-24
WO2008139122A2 (fr) 2008-11-20
US20100323985A1 (en) 2010-12-23
CA2686505A1 (fr) 2008-11-20

Similar Documents

Publication Publication Date Title
WO2008139122A3 (fr) Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation, et leurs utilisations
WO2008148967A3 (fr) Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation, et leurs utilisations
WO2006087759A3 (fr) Composition pharmaceutique comprenant de la curcumine et du resveratrol et leurs utilisations dans le domaine medical
WO2008139123A3 (fr) Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation, et leurs utilisations
WO2011148328A3 (fr) Procédé cosmétique pour le maquillage et/ou le soin de la peau et/ou des lèvres
WO2009074735A3 (fr) Utilisation d'un nouvel agent naturel dans des compositions cosmetiques
GB0622038D0 (en) Use of para-coumaric acid or para-hydroxycinnamic acid derivatives in cosmetic or dermatological compositions
WO2007038459A3 (fr) Composes de carboxyamine et leurs methodes d'utilisation
WO2009040420A3 (fr) Utilisation d'un monoterpène pour accroître une réparation tissulaire
WO2008034764A3 (fr) Préparations cosmétiques à base de polymère gravé moléculairement
IL206443A0 (en) Polysaccharide derivatives of lipoic acid, their preparation, use as skin cosmetics and medical devices
WO2007059979A3 (fr) Traitement d'une allergie par administration épicutanée d'un allergène
WO2008037380A3 (fr) Mélanges d'alkylbenzoates
WO2009044279A3 (fr) Peptide présentant une activité antimicrobienne et/ou bio-tensioactive
EP3330252A3 (fr) Composés à base d'isoprényle et procédés associés
WO2008076954A3 (fr) Composés hétérocycliques et procédés d'utilisation de ceux-ci
WO2008101692A3 (fr) Applications cosmétiques et pharmaceutique de la n-acétylhydroxyproline
WO2008107092A3 (fr) Utilisation de dérivés d'acide 4-hydroxyphénoxy acétique
WO2008148966A3 (fr) Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation, et leurs utilisations
WO2008046796A3 (fr) Utilisation de c10-c14-alcane-1,2-diols pour l'élaboration d'une composition destinée à la prophylaxie et/ou le traitement d'infections à dermatophytes
WO2008012107A3 (fr) Utilisation de polyéthylène glycol dans les troubles ou maladies topiques liés à l'inflammation et dans la cicatrisation des plaies
WO2007113531A8 (fr) Administration de médicament topique
WO2007108883A3 (fr) Compositions pour depot important et leurs utilisations
WO2009106555A3 (fr) Gel de sucralfate sterilise
BRPI0914462A2 (pt) "composição tópica, método de prevenção ou redução da ocorrência de tratamento de acne e uso de uma composição"

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08788212

Country of ref document: EP

Kind code of ref document: A2

WWE Wipo information: entry into national phase

Ref document number: 2008788212

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2686505

Country of ref document: CA

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 12599674

Country of ref document: US

点击 这是indexloc提供的php浏览器服务，不要输入任何密码和下载