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WO2008138337A3 - An oligo peptide synthesis and a cleavage and evaporation apparatus - Google Patents

An oligo peptide synthesis and a cleavage and evaporation apparatus Download PDF

Info

Publication number
WO2008138337A3
WO2008138337A3 PCT/DK2008/000173 DK2008000173W WO2008138337A3 WO 2008138337 A3 WO2008138337 A3 WO 2008138337A3 DK 2008000173 W DK2008000173 W DK 2008000173W WO 2008138337 A3 WO2008138337 A3 WO 2008138337A3
Authority
WO
WIPO (PCT)
Prior art keywords
holder
lines
centre line
centre
drive motor
Prior art date
Application number
PCT/DK2008/000173
Other languages
French (fr)
Other versions
WO2008138337A2 (en
Inventor
Peter Jepsen
Original Assignee
Alcorlab A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcorlab A/S filed Critical Alcorlab A/S
Publication of WO2008138337A2 publication Critical patent/WO2008138337A2/en
Publication of WO2008138337A3 publication Critical patent/WO2008138337A3/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00279—Features relating to reactor vessels
    • B01J2219/00306—Reactor vessels in a multiple arrangement
    • B01J2219/00324—Reactor vessels in a multiple arrangement the reactor vessels or wells being arranged in plates moving in parallel to each other
    • B01J2219/00328—Movement by linear translation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00351—Means for dispensing and evacuation of reagents
    • B01J2219/00389—Feeding through valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00351—Means for dispensing and evacuation of reagents
    • B01J2219/00389—Feeding through valves
    • B01J2219/00405—Sliding valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068—Means for controlling the apparatus of the process
    • B01J2219/00686—Automatic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00725—Peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Vapour Deposition (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)

Abstract

An apparatus comprises a drive motor having an output shaft. The apparatus further comprises a holder defining a centre line and comprising a number of receptors for receiving a corresponding number of vessels. The receptors are located on a first circle having its centre on the centre line. The holder has a coupling for connecting the holder to a drive motor, the holder being journalled horizontally and rotatably for stepwise revolving around the centre line powered by the drive motor. The apparatus further comprises a number of synthesis material lines and valves controlling the synthesis material lines, the lines and valves are located relatively to on a lid, each of the lines communicating with a supply container and each of the lines defining a discharge end. The discharge ends are positioned on a second circle having its centre on the centre line for allowing a specific discharge end to be positioned above a specific vessel received in the holder. Vials are optionally located below the vessels.
PCT/DK2008/000173 2007-05-09 2008-05-09 An oligo peptide synthesis and a cleavage and evaporation apparatus WO2008138337A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07388033.8 2007-05-09
EP07388033 2007-05-09

Publications (2)

Publication Number Publication Date
WO2008138337A2 WO2008138337A2 (en) 2008-11-20
WO2008138337A3 true WO2008138337A3 (en) 2009-10-22

Family

ID=39673411

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DK2008/000173 WO2008138337A2 (en) 2007-05-09 2008-05-09 An oligo peptide synthesis and a cleavage and evaporation apparatus

Country Status (1)

Country Link
WO (1) WO2008138337A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108752418B (en) * 2018-08-08 2024-01-30 湖南科技学院 Multichannel polypeptide synthesis reaction device and operation method thereof

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998057181A1 (en) * 1997-06-10 1998-12-17 Pharmacopeia, Inc. Methods and apparatus for universal fluid exchange
WO1999065602A2 (en) * 1998-06-16 1999-12-23 Northwest Engineering, Inc. Multi-well rotary synthesizer
US20020001849A1 (en) * 1990-03-02 2002-01-03 Copeland Keith G. Automated biological reaction apparatus
US20020028159A1 (en) * 1999-12-13 2002-03-07 Michal Lebl Oligonucleotide synthesizer
US6989133B1 (en) * 1998-12-30 2006-01-24 Mwg-Biotech Ag Device for carrying out chemical reactions
EP1785190A1 (en) * 2005-11-09 2007-05-16 JEPSEN, Peter Synthesis apparatus having rotatable, interchangeable reaction holders

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020001849A1 (en) * 1990-03-02 2002-01-03 Copeland Keith G. Automated biological reaction apparatus
WO1998057181A1 (en) * 1997-06-10 1998-12-17 Pharmacopeia, Inc. Methods and apparatus for universal fluid exchange
WO1999065602A2 (en) * 1998-06-16 1999-12-23 Northwest Engineering, Inc. Multi-well rotary synthesizer
US6989133B1 (en) * 1998-12-30 2006-01-24 Mwg-Biotech Ag Device for carrying out chemical reactions
US20020028159A1 (en) * 1999-12-13 2002-03-07 Michal Lebl Oligonucleotide synthesizer
EP1785190A1 (en) * 2005-11-09 2007-05-16 JEPSEN, Peter Synthesis apparatus having rotatable, interchangeable reaction holders
WO2007054091A1 (en) * 2005-11-09 2007-05-18 Alcorlab A/S An oligo peptide synthesis apparatus
EP1963015A1 (en) * 2005-11-09 2008-09-03 Alcorlab A/S An oligo peptide synthesis apparatus

Also Published As

Publication number Publication date
WO2008138337A2 (en) 2008-11-20

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