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WO2008137599A3 - 2-alkoxyestradiol analogs and pharmaceutical preparations - Google Patents

2-alkoxyestradiol analogs and pharmaceutical preparations Download PDF

Info

Publication number
WO2008137599A3
WO2008137599A3 PCT/US2008/062294 US2008062294W WO2008137599A3 WO 2008137599 A3 WO2008137599 A3 WO 2008137599A3 US 2008062294 W US2008062294 W US 2008062294W WO 2008137599 A3 WO2008137599 A3 WO 2008137599A3
Authority
WO
WIPO (PCT)
Prior art keywords
alkoxyestradiol
analogs
pharmaceutical preparations
proliferative
novel
Prior art date
Application number
PCT/US2008/062294
Other languages
French (fr)
Other versions
WO2008137599A2 (en
Inventor
Pemmaraju N Rao
James W Cessac
Original Assignee
Evestra Inc
Pemmaraju N Rao
James W Cessac
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evestra Inc, Pemmaraju N Rao, James W Cessac filed Critical Evestra Inc
Publication of WO2008137599A2 publication Critical patent/WO2008137599A2/en
Publication of WO2008137599A3 publication Critical patent/WO2008137599A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

Novel 2-alkoxyestradiol analogs, pharmaceutical compositions and methods of treatment of proliferative and angiogenesis associated conditions are disclosed.
PCT/US2008/062294 2007-05-01 2008-05-01 2-alkoxyestradiol analogs and pharmaceutical preparations WO2008137599A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US91535907P 2007-05-01 2007-05-01
US60/915,359 2007-05-01
US94116207P 2007-05-31 2007-05-31
US60/941,162 2007-05-31

Publications (2)

Publication Number Publication Date
WO2008137599A2 WO2008137599A2 (en) 2008-11-13
WO2008137599A3 true WO2008137599A3 (en) 2008-12-24

Family

ID=39944205

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/062294 WO2008137599A2 (en) 2007-05-01 2008-05-01 2-alkoxyestradiol analogs and pharmaceutical preparations

Country Status (1)

Country Link
WO (1) WO2008137599A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110078604B (en) * 2019-05-08 2021-12-03 台州学院 Preparation method of indeno-indanone derivative

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110183298B (en) * 2019-05-10 2021-09-17 台州学院 Preparation method of dibenzopentene derivative
CN111410677B (en) * 2020-03-02 2023-05-30 周亚耀 2-methoxyestramustine and derivatives, preparation method and application thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5892069A (en) * 1993-08-06 1999-04-06 The Children's Medical Center Corporation Estrogenic compounds as anti-mitotic agents
US6054598A (en) * 1997-03-13 2000-04-25 Pharm-Eco Laboratories, Inc. Synthesis of 2-alkoxyestradiols
US6852710B2 (en) * 2001-06-11 2005-02-08 Southwest Foundation For Biomedical Research 2-alkoxyestradiol analogs with antiproliferative and antimitotic activity

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5892069A (en) * 1993-08-06 1999-04-06 The Children's Medical Center Corporation Estrogenic compounds as anti-mitotic agents
US6054598A (en) * 1997-03-13 2000-04-25 Pharm-Eco Laboratories, Inc. Synthesis of 2-alkoxyestradiols
US6852710B2 (en) * 2001-06-11 2005-02-08 Southwest Foundation For Biomedical Research 2-alkoxyestradiol analogs with antiproliferative and antimitotic activity

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110078604B (en) * 2019-05-08 2021-12-03 台州学院 Preparation method of indeno-indanone derivative

Also Published As

Publication number Publication date
WO2008137599A2 (en) 2008-11-13

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