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WO2008130591A3 - Using trefoil polypeptides to treat eye lesions associated with ophthalmic procedures - Google Patents

Using trefoil polypeptides to treat eye lesions associated with ophthalmic procedures Download PDF

Info

Publication number
WO2008130591A3
WO2008130591A3 PCT/US2008/004950 US2008004950W WO2008130591A3 WO 2008130591 A3 WO2008130591 A3 WO 2008130591A3 US 2008004950 W US2008004950 W US 2008004950W WO 2008130591 A3 WO2008130591 A3 WO 2008130591A3
Authority
WO
WIPO (PCT)
Prior art keywords
lesions associated
trefoil
ophthalmic procedures
treat eye
eye lesions
Prior art date
Application number
PCT/US2008/004950
Other languages
French (fr)
Other versions
WO2008130591A2 (en
Inventor
Chee-Wai Woon
Nicholas P Barker
Original Assignee
Gi Company Inc
Chee-Wai Woon
Nicholas P Barker
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gi Company Inc, Chee-Wai Woon, Nicholas P Barker filed Critical Gi Company Inc
Publication of WO2008130591A2 publication Critical patent/WO2008130591A2/en
Publication of WO2008130591A3 publication Critical patent/WO2008130591A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

A pharmaceutical composition containing a trefoil polypeptide may be used to treat a patient having a lesion of the eye, or pain associated therewith, caused by or associated with an ophthalmic procedure. Trefoil peptides useful for such a composition are disclosed.
PCT/US2008/004950 2007-04-18 2008-04-17 Using trefoil polypeptides to treat eye lesions associated with ophthalmic procedures WO2008130591A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91249207P 2007-04-18 2007-04-18
US60/912,492 2007-04-18

Publications (2)

Publication Number Publication Date
WO2008130591A2 WO2008130591A2 (en) 2008-10-30
WO2008130591A3 true WO2008130591A3 (en) 2008-12-24

Family

ID=39876124

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/004950 WO2008130591A2 (en) 2007-04-18 2008-04-17 Using trefoil polypeptides to treat eye lesions associated with ophthalmic procedures

Country Status (2)

Country Link
AR (1) AR066217A1 (en)
WO (1) WO2008130591A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2017311636B2 (en) 2016-08-19 2023-08-10 Orasis Pharmaceuticals Ltd. Ophthalmic pharmaceutical compositions and uses relating thereto
WO2023285878A1 (en) * 2021-07-13 2023-01-19 Aviation-Ophthalmology Methods for detecting, treating, and preventing gpr68-mediated ocular diseases, disorders, and conditions

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030186886A1 (en) * 1996-04-12 2003-10-02 Podolsky Daniel K. Treating eye disorders using intestinal trefoil proteins
US20070042951A1 (en) * 2003-10-08 2007-02-22 Allergan, Inc. Pharmaceutical compositions comprising alpha-2-adrenergics and trefoil factor family peptides

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030186886A1 (en) * 1996-04-12 2003-10-02 Podolsky Daniel K. Treating eye disorders using intestinal trefoil proteins
US20070042951A1 (en) * 2003-10-08 2007-02-22 Allergan, Inc. Pharmaceutical compositions comprising alpha-2-adrenergics and trefoil factor family peptides

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
GOKE ET AL.: "Trefoil peptides promote restitution of wounded corneal epithelial cells", EXP. CELL RES., vol. 264, no. 2, 1 April 2001 (2001-04-01), pages 337 - 344, Retrieved from the Internet <URL:http://www.sciencedirect.com/science> *

Also Published As

Publication number Publication date
AR066217A1 (en) 2009-08-05
WO2008130591A2 (en) 2008-10-30

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