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WO2008127964A3 - Methods and systems for applying therapeutic agent to a medical device - Google Patents

Methods and systems for applying therapeutic agent to a medical device Download PDF

Info

Publication number
WO2008127964A3
WO2008127964A3 PCT/US2008/059847 US2008059847W WO2008127964A3 WO 2008127964 A3 WO2008127964 A3 WO 2008127964A3 US 2008059847 W US2008059847 W US 2008059847W WO 2008127964 A3 WO2008127964 A3 WO 2008127964A3
Authority
WO
WIPO (PCT)
Prior art keywords
medical device
therapeutic agent
systems
methods
applying therapeutic
Prior art date
Application number
PCT/US2008/059847
Other languages
French (fr)
Other versions
WO2008127964A2 (en
Inventor
John Benco
Yixin Xu
Original Assignee
Boston Scientific Scimed, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boston Scientific Scimed, Inc. filed Critical Boston Scientific Scimed, Inc.
Priority to EP08745454A priority Critical patent/EP2160483A2/en
Publication of WO2008127964A2 publication Critical patent/WO2008127964A2/en
Publication of WO2008127964A3 publication Critical patent/WO2008127964A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25D—PROCESSES FOR THE ELECTROLYTIC OR ELECTROPHORETIC PRODUCTION OF COATINGS; ELECTROFORMING; APPARATUS THEREFOR
    • C25D9/00—Electrolytic coating other than with metals
    • C25D9/02—Electrolytic coating other than with metals with organic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25D—PROCESSES FOR THE ELECTROLYTIC OR ELECTROPHORETIC PRODUCTION OF COATINGS; ELECTROFORMING; APPARATUS THEREFOR
    • C25D13/00—Electrophoretic coating characterised by the process
    • C25D13/04—Electrophoretic coating characterised by the process with organic material
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25D—PROCESSES FOR THE ELECTROLYTIC OR ELECTROPHORETIC PRODUCTION OF COATINGS; ELECTROFORMING; APPARATUS THEREFOR
    • C25D7/00—Electroplating characterised by the article coated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/80—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special chemical form

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Materials Engineering (AREA)
  • Metallurgy (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

In methods and systems for applying a coating to a medical device, such as a coating comprising a therapeutic agent, electrons may be transferred from an electrode to ionize a therapeutic agent dissolved in an electrolytic solution. The ionized therapeutic agent may then be electrochemically delivered to the medical device. The medical device may be a stent, which may have a porous surface.
PCT/US2008/059847 2007-04-12 2008-04-10 Methods and systems for applying therapeutic agent to a medical device WO2008127964A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP08745454A EP2160483A2 (en) 2007-04-12 2008-04-10 Methods and systems for applying therapeutic agent to a medical device

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91135807P 2007-04-12 2007-04-12
US60/911,358 2007-04-12

Publications (2)

Publication Number Publication Date
WO2008127964A2 WO2008127964A2 (en) 2008-10-23
WO2008127964A3 true WO2008127964A3 (en) 2009-12-10

Family

ID=39852723

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/059847 WO2008127964A2 (en) 2007-04-12 2008-04-10 Methods and systems for applying therapeutic agent to a medical device

Country Status (3)

Country Link
US (1) US20080251391A1 (en)
EP (1) EP2160483A2 (en)
WO (1) WO2008127964A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9463262B2 (en) 2010-11-04 2016-10-11 Sanyo Chemical Industries, Ltd. Cell adhesive material for biological tissue

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040067301A1 (en) * 1998-07-07 2004-04-08 Schneider (Usa), Inc. Medical device with porous surface for controlled drug release and method of making the same
US20060124466A1 (en) * 2004-12-09 2006-06-15 Scimed Life Systems, Inc. Method and apparatus for coating a medical device by electroplating
US20060184092A1 (en) * 2005-02-11 2006-08-17 Liliana Atanasoska Internal medical devices for delivery of therapeutic agent in conjunction with a source of electrical power

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2356465A1 (en) * 1976-07-02 1978-01-27 Benoist Girard & Cie PROCESS FOR MANUFACTURING PARTS WITH A GRENUE SURFACE AND PART OBTAINED, IN PARTICULAR SURGICAL PROSTHESES
US5091205A (en) 1989-01-17 1992-02-25 Union Carbide Chemicals & Plastics Technology Corporation Hydrophilic lubricious coatings
US5843289A (en) * 1996-01-22 1998-12-01 Etex Corporation Surface modification of medical implants
US6447664B1 (en) * 1999-01-08 2002-09-10 Scimed Life Systems, Inc. Methods for coating metallic articles
AU2001229351A1 (en) * 2000-01-25 2001-08-07 Boston Scientific Limited Manufacturing medical devices by vapor deposition
US7001421B2 (en) * 2003-02-28 2006-02-21 Medtronic Vascular, Inc. Stent with phenoxy primer coating
US20050159805A1 (en) * 2004-01-20 2005-07-21 Jan Weber Functional coatings and designs for medical implants
US20050266040A1 (en) * 2004-05-28 2005-12-01 Brent Gerberding Medical devices composed of porous metallic materials for delivering biologically active materials

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040067301A1 (en) * 1998-07-07 2004-04-08 Schneider (Usa), Inc. Medical device with porous surface for controlled drug release and method of making the same
US20060124466A1 (en) * 2004-12-09 2006-06-15 Scimed Life Systems, Inc. Method and apparatus for coating a medical device by electroplating
US20060184092A1 (en) * 2005-02-11 2006-08-17 Liliana Atanasoska Internal medical devices for delivery of therapeutic agent in conjunction with a source of electrical power

Also Published As

Publication number Publication date
EP2160483A2 (en) 2010-03-10
WO2008127964A2 (en) 2008-10-23
US20080251391A1 (en) 2008-10-16

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