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WO2008116178A3 - Systems and methods for diagnosis and prognosis of colorectal cancer - Google Patents

Systems and methods for diagnosis and prognosis of colorectal cancer Download PDF

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Publication number
WO2008116178A3
WO2008116178A3 PCT/US2008/057884 US2008057884W WO2008116178A3 WO 2008116178 A3 WO2008116178 A3 WO 2008116178A3 US 2008057884 W US2008057884 W US 2008057884W WO 2008116178 A3 WO2008116178 A3 WO 2008116178A3
Authority
WO
WIPO (PCT)
Prior art keywords
colorectal cancer
diagnosis
systems
methods
prognosis
Prior art date
Application number
PCT/US2008/057884
Other languages
French (fr)
Other versions
WO2008116178A2 (en
WO2008116178A8 (en
Inventor
Robert J Coffey
Bruce J Aronow
Jeffrey L Franklin
Timothy Yeatman
Sanne K H Olesen
Gregory Bloom
Original Assignee
Univ Vanderbilt
H Lee Moffitt Cancer And Res I
Cincinnati Children S Hospital
Robert J Coffey
Bruce J Aronow
Jeffrey L Franklin
Timothy Yeatman
Sanne K H Olesen
Gregory Bloom
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Vanderbilt, H Lee Moffitt Cancer And Res I, Cincinnati Children S Hospital, Robert J Coffey, Bruce J Aronow, Jeffrey L Franklin, Timothy Yeatman, Sanne K H Olesen, Gregory Bloom filed Critical Univ Vanderbilt
Publication of WO2008116178A2 publication Critical patent/WO2008116178A2/en
Publication of WO2008116178A3 publication Critical patent/WO2008116178A3/en
Publication of WO2008116178A8 publication Critical patent/WO2008116178A8/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57419—Specifically defined cancers of colon
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)

Abstract

Methods and systems are described for using in making a diagnosis of colorectal cancer in a subject. A method can include providing a biological sample from the subject; determining an amount in the sample of at least one peptide marker, selected from a group of markers as described herein; and comparing the amount of the at least one peptide marker in the sample, if present, to a control level of the at least one peptide marker, wherein the subject is diagnosed as having colorectal cancer or a risk thereof if there is a measurable difference in the amount of the at least one peptide marker in the sample as compared to the control level.
PCT/US2008/057884 2007-03-21 2008-03-21 Systems and methods for diagnosis and prognosis of colorectal cancer WO2008116178A2 (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US89602007P 2007-03-21 2007-03-21
US60/896,020 2007-03-21
US93830707P 2007-05-16 2007-05-16
US60/938,307 2007-05-16
US96898807P 2007-08-30 2007-08-30
US60/968,988 2007-08-30
US97183907P 2007-09-12 2007-09-12
US60/971,839 2007-09-12

Publications (3)

Publication Number Publication Date
WO2008116178A2 WO2008116178A2 (en) 2008-09-25
WO2008116178A3 true WO2008116178A3 (en) 2008-12-04
WO2008116178A8 WO2008116178A8 (en) 2009-09-17

Family

ID=39766792

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/057884 WO2008116178A2 (en) 2007-03-21 2008-03-21 Systems and methods for diagnosis and prognosis of colorectal cancer

Country Status (1)

Country Link
WO (1) WO2008116178A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2239577A1 (en) * 2009-04-07 2010-10-13 Vereniging voor Christelijk Hoger Onderwijs, Wetenschappelijk Onderzoek en Patiëntenzorg Protein-based methods and compositions for the diagnosis of colorectal adenocarcinoma
NO2829881T3 (en) * 2010-07-14 2018-01-20
US9141756B1 (en) 2010-07-20 2015-09-22 University Of Southern California Multi-scale complex systems transdisciplinary analysis of response to therapy
CN102586402A (en) * 2011-01-05 2012-07-18 苏州科贝生物技术有限公司 Kit for quantitative evaluation for long-term recurrent risk of colorectal cancer
GB2545361B (en) 2015-04-10 2018-01-24 Applied Proteomics Inc Methods of assessing colorectal cancer status
JP6984862B2 (en) * 2017-03-15 2021-12-22 国立大学法人金沢大学 Detection of colorectal cancer using blood chemokines as markers
TR202019592A2 (en) 2020-12-03 2022-06-21 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Solid pharmaceutical formulations of amorphous dapagliflozin

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHEN ET AL.: "Proteomic analysis of colonic myofibroblasts and effect on colon cancer cell proliferation", SURGERY, vol. 138, no. 2, pages 382 - 390, XP005059700 *
JOYCE ET AL.: "Microarray analysis to reveal genes involved in colon carcinogenesis", EXPERT OPIN. PHARMACOTHER., vol. 8, no. 7, 2007, pages 895 - 900 *

Also Published As

Publication number Publication date
WO2008116178A2 (en) 2008-09-25
WO2008116178A8 (en) 2009-09-17

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