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WO2008115165A2 - Procédé d'hydrolysation de concentré protéique de riz par des enzymes protéases - Google Patents

Procédé d'hydrolysation de concentré protéique de riz par des enzymes protéases Download PDF

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Publication number
WO2008115165A2
WO2008115165A2 PCT/US2005/013389 US2005013389W WO2008115165A2 WO 2008115165 A2 WO2008115165 A2 WO 2008115165A2 US 2005013389 W US2005013389 W US 2005013389W WO 2008115165 A2 WO2008115165 A2 WO 2008115165A2
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WO
WIPO (PCT)
Prior art keywords
rice protein
dispersion
degree
weight
hydrolyzed
Prior art date
Application number
PCT/US2005/013389
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English (en)
Other versions
WO2008115165A3 (fr
Inventor
Dharmen B. Makwana
Clodualdo C. Maningat
Sukh D. Bassi
Original Assignee
Mgp Ingredients, Inc.
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Filing date
Publication date
Application filed by Mgp Ingredients, Inc. filed Critical Mgp Ingredients, Inc.
Publication of WO2008115165A2 publication Critical patent/WO2008115165A2/fr
Publication of WO2008115165A3 publication Critical patent/WO2008115165A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/645—Proteins of vegetable origin; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0208—Tissues; Wipes; Patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0212—Face masks
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/02—Preparations containing skin colorants, e.g. pigments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/14—Preparations for removing make-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/10—Washing or bathing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/004—Preparations used to protect coloured hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/02—Preparations for cleaning the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/06—Preparations for styling the hair, e.g. by temporary shaping or colouring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/12—Preparations containing hair conditioners
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/005—Preparations for sensitive skin

Definitions

  • the present invention is broadly concerned with hydrolyzed rice protein and uses thereof, particularly in connection with cosmetic products such as shampoos, shampoo conditioners, hair styling gels, hair conditioners, hair reparative, hair tonics, hair fixatives, hair mousses, bath and shower gels, liquid soaps, moisturizing sprays, makeup, pressed powder formulations, lip products, bath additives, sanitizing wipes, hand sanitizers, premoistened towelettes, skin lotions and creams, shaving creams, sunscreens, and anti-wrinkle and color cosmetics.
  • cosmetic products such as shampoos, shampoo conditioners, hair styling gels, hair conditioners, hair reparative, hair tonics, hair fixatives, hair mousses, bath and shower gels, liquid soaps, moisturizing sprays, makeup, pressed powder formulations, lip products, bath additives, sanitizing wipes, hand sanitizers, premoistened towelettes, skin lotions and creams, shaving creams, sunscreens, and anti-wrinkle
  • hydrolyzed rice protein which is preferably in the form of a mixture of amino acids, peptides and/or protein fractions derived from the hydrolysis of naturally occurring rice protein; such mixtures, when used in cosmetic products, provide enhanced properties.
  • a closer look at the ingredient listing in most product packages reveals the use of hydrolyzed grain and oilseed proteins from wheat, corn, oat, and soy among others, in hair and skin care products.
  • Animal-based ingredients such as hydrolyzed collagen and keratin are becoming rare.
  • Hydrolyzed grain and oilseed proteins provide benefits to hair by improving the body, manageability, shine, dry combing and moisture retention.
  • the quateraized derivatives of hydrolyzed plant or vegetable proteins have excellent conditioning properties and provide greater ease of wet combing.
  • hydrolyzed grain and oil seed proteins promote effective moisturizing and dermal conditioning, combat chapping and irritation, and resist pollutant and irritant damage.
  • rice which is the staple food in the densely populated countries of Asia, especially Bangladesh, Burma, Cambodia, China, Indonesia, Korea, Laos, Vietnam, Thailand, Sri Lanka, and the Philippines. Rice provides as much as 75% of the daily caloric intake of people in these Asian countries.
  • the major components of rice are starch and protein representing about 90% of the grain. Rice starch exists as compound granules, and the individual granule has an angular or polyhedral shape. The dimension of rice starch is around 3-5 microns in diameter. In general, rice has 7-9% protein content.
  • the protein component of rice consists of four fractions: glutelin, prolamin, globulin, and albumin.
  • the major amino acids in rice proteins are glutamic acid, aspartic acid, arginine, and leucine.
  • the present invention is directed to a new form of rice protein, namely hydrolyzed rice protein and derivatives thereof, as well as uses of such protein products in cosmetic formulations.
  • the preferred hydrolyzed rice protein and derivatives thereof in accordance with the invention comprise a mixture of amino acids, peptides and/or protein fractions derived from the hydrolysis of the naturally occurring rice protein. Such hydrolysis is preferably carried out enzymatically, but if desired acid hydrolysis can also be employed.
  • the hydrolyzed rice protein is typically in the form of a mixture having an amino acid, peptide and/or protein fragment molecular weight range of from about 75-5,000 with an average molecular weight of from about 1,500-2,500.
  • a hydrolyzed rice protein product of relatively high molecular weight is provided, with a molecular weight range for the respective peptides and/or fragments therein of from about 1,000-5,000 and with an average molecular weight of from about 3,000-4,000.
  • a lower molecular weight fraction (sometimes referred to as a rice amino acid fraction) is produced wherein the respective amino acids and peptides exhibit a molecular weight range of from about 75-1,000, with an average molecular weight of from about 100- 300.
  • the hydrolyzed rice protein and derivatives thereof can be produced as a dry powder, this is sometimes difficult and normally the product is in the form of an aqueous dispersion containing rice protein or derivatives at a level of from about 18-35% by weight, more preferably from about 23-27% by weight.
  • hydrolyzed rice protein refers to changes in the structure of the individual amino acids, peptides and/or protein fragments produced by amino acid addition, deletion, replacement, substitution and/or modifications; mutants produced by recombinant and/or DNA shuffling; quaternized species; and all other chemically synthesized/modified forms of the individual amino acids, peptides and/or protein fragments which retain at least in part some activity of the initial hydrolyzed amino acids, peptides and/or protein fragments.
  • One particularly preferred class of hydrolyzed rice protein derivatives is the lipid derivatives, especially those synthesized using C12-C22 fatty acids.
  • the term "hydrolyzed rice protein" is intended to embrace and cover not only the amino acids, peptides and/or protein fractions derived from the hydrolysis of naturally occurring rice protein but also all “derivatives" as herein defined.
  • the rice products of the invention can be used to good effect in a variety of cosmetic formulations which include at least one ingredient selected from the group consisting of humectants, emollients, conditioners, thickeners, moisturizing agents, opacifiers, pearl agents, buffering agents, slip agents, feel agents, anti-static agents, acidifiers, preservatives, film formers, plasticizers, setting agents and suspending agents (usually, each of the foregoing ingredients when used is present at a level of from about 0.05-10% by weight).
  • An amount of hydrolyzed rice protein or derivative thereof is incorporated into this type of cosmetic formulation, usually at a level of from about 1-10% by weight, more preferably from about 3-8% by weight.
  • the preferred rice protein products are in the form of liquid dispersions, it is a simple matter to add the rice protein product to the cosmetic formulations during preparation thereof.
  • the formulations of the invention comprise from about 10-95% by weight water, more preferably from about 20-75% by weight water.
  • cosmetic products which can benefit from incorporation of the rice products of the invention are those selected from the group consisting of shampoos, shampoo conditioners, hair styling gels, hair conditioners, hair reparatives, hair tonics, hair fixatives, hair mousses, bath and shower gels, liquid soaps, moisturizing sprays, makeup, pressed powder formulations, lip products, bath additives, sanitizing wipes, hand sanitizers, premoistened towelettes, skin lotions and creams, shaving creams, sunscreens and anti-wrinkle and color cosmetics.
  • shampoos shampoo conditioners, hair styling gels, hair conditioners, hair reparatives, hair tonics, hair fixatives, hair mousses, bath and shower gels, liquid soaps, moisturizing sprays, makeup, pressed powder formulations, lip products, bath additives, sanitizing wipes, hand sanitizers, premoistened towelettes, skin lotions and creams, shaving creams, sunscreens and anti-wrinkle and color cosmetics.
  • the shampoos and shampoo conditioners further comprise at least about 6% by weight detergent; the hairstyling gels further comprise a gel-forming polymer system; the hair conditioners further comprise at least about 0.3% by weight cationic hair conditioner; the hair reparatives further comprise at least about 2% by weight cationic hair conditioner; the bath and shower gels further comprise at least about 25% by weight surfactant; the skin lotions and creams further comprise at least about 2% by weight of a cream former; the sunscreens further comprise a sunblocking agent; and the shaving creams further comprise at least about 10% by weight detergent and have a basic pH.
  • FIG. 1 is a schematic flow diagram illustrating the steps involved in the preferred process for the production of hydrolyzed rice protein.
  • This example describes a preferred procedure for the preparation of hydrolyzed rice protein, using rice protein concentrate as a starting material.
  • the concentrate was obtained by methods known in the art.
  • the following Table sets forth the amino acid profile of the protein fraction of the concentrate.
  • the hydrolysis method is schematically illustrated in FIG. 1, and was carried out as follows. First, 750 gallons of soft water was heated to 140 degree F and placed in a reaction tank. 1,000 pounds of the above-described rice protein concentrate was added to the reaction tank with agitation to completely disperse the meal. At this point, 22 pounds of 50% NaOH solution was added to the reaction tank for 1 hour to solubilize the proteins and create the alkaline dispersion 10 of FIG. 1.
  • the protein slurry was treated with 15 pounds of protease enzyme (step 12), using a commercially available enzyme (Alcalase, Novo) and hydrolyzed for 2 hours with agitation. During this hydrolysis, the pH was maintained between 7.5-8.0 using 50% NaOH. A second dose of the Alcalase protease enzyme (15 pounds) was then added to the slurry followed by agitation for 2 hours. During this period, there was no pH adjustment.
  • step 14 the pH of the slurry was adjusted to 6.5 using lactic acid, whereupon a second protease treatment (step 16) was carried out.
  • This treatment included addition of 10 pounds of a second protease enzyme (Flavorzyme, Novo) followed by agitation for 4 hours.
  • 3 pounds of Dual Protease Enzyme (Enzyme Development Corp.) was dispersed in 1 gallon of tap water and added to the slurry followed by the addition of 10 pounds of Neutrase (Novo). The slurry was then agitated for an additional 2 hours to continue the hydrolysis process.
  • step 18 lactic acid was added to the slurry to lower the pH to 4.5, followed by the addition of 8 pounds sodium metabisulfite with agitation for 10 minutes.
  • step 20 the slurry was heated to 160 degree F to deactivate all protease enzymes.
  • the slurry containing hydrolyzed rice proteins was then processed in a rotary vacuum filter (step 22) to remove insolubles, and the filtrate was clarified by passage through a packed-house filter unit (step 24).
  • the clarified filtrate from step 24 was then fed to a nanofiltration membrane system, in order to generate a permeate and a retentate having different molecular weight profiles (step 26) after the retentate reached about 31% by weight solids using a refractometer.
  • the membrane system was selected so that the lower molecular weight permeate proteins were generally below a molecular weight of 1,000, whereas the retentate proteins had a molecular weight of above about 1,000.
  • the retentate fraction was first treated by the addition of preservatives (step 28), namely 1% by weight Germaben II and 0.3% by weight Dowicil 200. The retentate was then chilled to 34-35 degree F and allowed to stand for 16-24 hours
  • step 30 The chilled retentate was then cold-filtered in a packed-house filter unit to remove haziness (step 32), and additional preservatives were added (15% extra Germaben II and Dowicil 200).
  • the resulting retentate was aged 1-2 weeks (step 34) filtered (step 36) and packed in aqueous liquid form in 5-gallon jugs or 55-gallon drums (step 38) as hydrolyzed rice protein 39.
  • This liquid contained about 10% by weight protein.
  • the permeate fraction was conventionally evaporated (step 40) to achieve a solids content of about 34% by weight, using a refractometer. Preservatives were then added (1% Germaben II and 0.3% Dowicil 200) followed by mixing for 1 hour (step 42).
  • the retentate was then subjected to the same aging, filtration and packaging steps 34, 36 and 38 as the retentate, to produce aqueous liquid rice amino acid product 44. This liquid product contained about 4.5% by weight protein.
  • the rice amino acid product was analyzed to contain (wb) 0.28% aspaitic acid, 0.13% threonine, 0.15% serine, 0.38% glutamic acid, 0.09% proline, 0.17% glycine, 0.17% alanine, 0.03% cysteine, 0.14% valine, 0.04% methionine, 0.09% isoleucine, 0.17% leucine, ⁇ 0.01 % tyrosine, 0.13% phenylalanine, 0.02% histidine, 0.08% lysine, 0.11% arginine, and ⁇ 0.01% tryptophan.
  • the two products developed using this process comprise peptides and/or protein fragments derived from naturally occurring rice protein
  • the reference to "hydrolyzed rice protein” and “rice amino acid” is a convenience, merely referring to the fact that the respective mixtures have different molecular weight profiles.
  • the products are "hydrolyzed rice protein” and this term is used herein to refer to both of these products and for that matter any product containing amino acids, peptides and/or protein fragments derived from naturally occurring rice protein via hydrolysis.
  • a rice amino acid product is produced by acid hydrolysis of rice protein concentrate.
  • 450 gallons of warm (160 degree F) water is transferred to a homomixer tank, followed by the addition of 2 gallons of concentrated HCl (36%).
  • the mixture is stirred and 950 pounds of rice protein concentrate is added, with continued stirring for 30 minutes.
  • the acidified slurry is then transferred to a glass-lined reactor and 448 gallons of concentrated HCl (36%) is added to the reactor.
  • the temperature of the mixture within the reactor is raised to 212-220 degree F using a heat exchanger, followed by mixing for 24 hours.
  • the hydrolyzate is cooled to 120-140 degree F, and 50% NaOH solution is added to adjust the pH to 6.0-7.0.
  • the neutralized hydrolyzate is then clarified using a rotary vacuum filter to remove solid particulates, and the clarified hydrolyzate is concentrated to the desired solids level (20-30%) in an evaporator.
  • Preservatives 1% Germaben and 0.3% Dowicil 200 are added.
  • the product is then chilled at 34-35 degree F for 16-24 hours. After chilling, the product is filtered using a packed-house filter unit to remove haziness.
  • the product is then aged for 1-2 weeks, and a final filtration is carried out using a packed-house filter unit.
  • the product is then packaged in suitable containers such as 5 gallon jugs or 55 gallon drums.
  • quaternized derivatives of hydrolyzed rice protein or rice amino acid are prepared.
  • 100 parts of the rice product either hydrolyzed rice protein or hydrolyzed rice amino acid
  • the pH of the mixture is adjusted to 9.1-9.3 using 50% NaOH.
  • Quab 342 product Alternatives to the Quab 342 product are 3-chloro-2- hydroxypropyl-N,N,N-dimethyloctadecylammonium chloride (Quab 426) or 3- chloro-2-hydroxypropyl-N,N,N-trimethylammonium chloride (Quat 188) to produce other derivatives.
  • the solution in the separate container is then added to the pH- adjusted rice mixture, followed by agitation for 16-24 hours.
  • the pH of the solution is then adjusted 4.4-4.6 using lactic acid (88%) solution.
  • the product is then filtered using a packed-house filter unit to remove particulates, followed by packaging.
  • the finished product is laurdimonium hydroxypropyl hydrolyzed rice protein (or laurdimonium hydroxypropyl rice amino acid). If Quab 426 is used, the product is steardimonium hydroxypropyl hydrolyzed rice protein (or steardimonium hydroxypropyl rice amino acid). If Quat 188 is used, the product is called hydroxypropyl trimonium hydrolyzed rice protein (or hydroxypropyl trimonium rice amino acid).
  • Hydrolyzed rice starch is produced by enzyme hydrolysis. 88.5% by weight (based on total weight of mixture) 750 degree C water is transferred into a homomixer tank followed by the addition of 0.5% by weight ⁇ -amylase. The mixture is stirred for at least 1.5 hours, and 10.0% by weight of rice starch is added during stirring. At the completion of hydrolysis, the enzyme in the slurry is deactivated by increasing the temperature of the slurry to 850 degree C for at least 1 hour.
  • hydrolyzed rice protein 96% by weight (based on total solids) hydrolyzed rice protein is added, together with 1% by weight (total solids basis) of a preservative comprising phenoxyethanol, isopropylparaben, isobutylparaben and butylparaben (sold by ISP as LiquiPar).
  • a preservative comprising phenoxyethanol, isopropylparaben, isobutylparaben and butylparaben (sold by ISP as LiquiPar).
  • the slurry is then chilled and filtered and adjusted to solids of 15% to 35%.
  • the parameters of this process may be varied in several respects. Examples include (weight bases as stated above): starting water - 70 - 90% protease enzyme - 0.2 - 1.0% rice starch - 5% - 15% hydrolysis time - 1.5 - 18 hours hydrolyzed rice protein (mix) - 1.0% - 99% hydrolyzed rice starch (mix) - 1.0% - 99%
  • Viscosity 8,000 ⁇ 15% (RVDV Spindle # 3, 10 rpm @ 25 degree C)
  • Viscosity RVDV Spindle T-B, 5 rpm @ 25 degree C
  • Viscosity RVDV Spindle T-F, 10 rpm 25 degree C
  • Viscosity 12,000 ⁇ 10% (RVDV Spindle # 4, 10 rpm @ 25 degree C) Procedure: 1. In a suitable primary tank meter out required amount of distilled water.
  • Viscosity 8,000 ⁇ 15% (RVDV Spindle # 3, 10 rpm @ 25 degree C) Procedure:
  • Viscosity RVDV T-B, 5 rpm @ 25 degree C
  • Viscosity RVDV Spindle T-F, 10 rpm @ 25 degree C
  • Procedure 1. Mix Part A in a primary tank and heat to 75 degree C.
  • Viscosity 12,000 ⁇ 10% (RVDV Spindle # 4, 10 rpm @ 25 degree C)
  • Viscosity 8,000 ⁇ 15% (RVDV Spindle # 3, 10 rpm @ 25 degree C) Procedure:
  • Viscosity RVDV Spindle T-B, 5 rpm @ 25 degree C
  • Procedure 1. In a suitable primary tank, meter out required amount of distilled water.
  • Viscosity 8,000 ⁇ 15% (RVDV Spindle # 3, 10 rpm @ 25°C)
  • Viscosity RVDV Spindle T-B, 5 rpm @ 25 degree C
  • Procedure 1. In a suitable primary tank, meter out required amount of distilled water.
  • Viscosity RVDV Spindle T-F, 10 rpm @ 25 degree C
  • Viscosity 12,000 ⁇ 10% (RVDV Spindle # 4, 10 rpm @ 25 degree C)
  • Viscosity RVDV Spindle T-B, 5 rpm @ 25 degree C
  • Viscosity RVDV Spindle T-B, 5 rpm @ 25 degree C
  • Procedure 1. In a suitable primary tank, meter out required amount of distilled water.
  • Viscosity 8,000 +15% (RVDV Spindle # 3, 10 rpm @ 25 degree C)
  • Viscosity 7,500 ⁇ 15% (RVDV Spindle # 3, 10 rpm @ 25 degree C) Procedure:
  • Viscosity RVDV Spindle T-F, 10 rpm @ 25 degree C
  • Viscosity RVDV Spindle T-B, 5 rpm @ 25 degree C
  • Viscosity RVDV Spindle T-B, 5 rpm @ 25 degree C
  • Procedure 1. In a suitable primary tank, meter out required amount of distilled water.
  • Viscosity 8,000 ⁇ 15% (RVDV Spindle #3, 10 rpm @ 25 degree C) Procedure:
  • Viscosity 8,000 ⁇ 15% (RVDV Spindle # 3, 10 rpm @ 25 degree C) Procedure:
  • Viscosity RVDV Spindle T-B, 5 rpm @ 25 degree C
  • Viscosity 12,000 ⁇ 10% (RVDV Spindle # 4, 10 rpm 25 degree C)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Cosmetics (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention concerne des compositions et des procédés de fabrication et d'utilisation de protéines hydrolysées de riz, et de dérivés de celles-ci. Les dérivés utiles comprennent des sels d'ammonium quaternaire de protéines et/ou d'acides aminés de riz. Les protéines hydrolysées de riz sont utiles dans des produits cosmétiques : shampooings, gels capillaires, mousses capillaires, gels de douche et de bain, savons liquides, lingettes humides, lotions cutanées, protections solaires, et analogues.
PCT/US2005/013389 2004-04-20 2005-04-20 Procédé d'hydrolysation de concentré protéique de riz par des enzymes protéases WO2008115165A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56384104P 2004-04-20 2004-04-20
US60/563,841 2004-04-20

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WO2008115165A2 true WO2008115165A2 (fr) 2008-09-25
WO2008115165A3 WO2008115165A3 (fr) 2009-05-22

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2344115A2 (fr) * 2008-10-10 2011-07-20 Johnson & Johnson Consumer Companies, Inc. Nettoyant régulant la brillance
WO2018050483A1 (fr) 2016-09-13 2018-03-22 Basf Se Hydrolysats de kératine de faible poids moléculaire
WO2018068947A2 (fr) 2016-09-13 2018-04-19 Basf Se Hydrolysats de protéines
CN110711168A (zh) * 2019-11-29 2020-01-21 桃源县兴隆米业科技开发有限公司 利用高必需氨基酸节米制备氨基酸护肤精华液的方法
KR20210058031A (ko) * 2019-11-13 2021-05-24 주식회사 에이치피앤씨 하이드롤라이즈드쌀단백질을 포함하는 피부 수분 개선용 화장료 조성물 및 이의 제조방법
FR3151214A1 (fr) * 2023-07-19 2025-01-24 Societe Industrielle Limousine D'application Biologique Principe actif à partir d’un isolat protéique d’Oryza sativa pour lutter contre l’inflammation cutanée.

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5716801A (en) * 1991-03-07 1998-02-10 Novo Nordisk A/S Method for production of a vegetable protein hydrolyzate with proteases
DE19502167C2 (de) * 1995-01-25 1997-02-06 Henkel Kgaa Verfahren zur Herstellung von Reisproteinhydrolysaten
JP4229236B2 (ja) * 2001-04-23 2009-02-25 エムジーピー イングリーディエンツ アイエヌシー． 加水分解されたホホバプロテインを調製する方法および加水分解されたホホバプロテインを含む調合物
FR2825925B1 (fr) * 2001-06-19 2005-01-28 Silab Sa Procede de preparation d'un principe actif a partir de riz, principe actif obtenu et compositions adaptees

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2344115A2 (fr) * 2008-10-10 2011-07-20 Johnson & Johnson Consumer Companies, Inc. Nettoyant régulant la brillance
WO2018050483A1 (fr) 2016-09-13 2018-03-22 Basf Se Hydrolysats de kératine de faible poids moléculaire
WO2018068947A2 (fr) 2016-09-13 2018-04-19 Basf Se Hydrolysats de protéines
KR20210058031A (ko) * 2019-11-13 2021-05-24 주식회사 에이치피앤씨 하이드롤라이즈드쌀단백질을 포함하는 피부 수분 개선용 화장료 조성물 및 이의 제조방법
KR102313996B1 (ko) * 2019-11-13 2021-10-19 (주)에이치피앤씨 하이드롤라이즈드쌀단백질을 포함하는 피부 수분 개선용 화장료 조성물 및 이의 제조방법
CN110711168A (zh) * 2019-11-29 2020-01-21 桃源县兴隆米业科技开发有限公司 利用高必需氨基酸节米制备氨基酸护肤精华液的方法
FR3151214A1 (fr) * 2023-07-19 2025-01-24 Societe Industrielle Limousine D'application Biologique Principe actif à partir d’un isolat protéique d’Oryza sativa pour lutter contre l’inflammation cutanée.

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