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WO2008113901A3 - Composition à libération prolongée de lévétiracetam et procédé de préparation. - Google Patents

Composition à libération prolongée de lévétiracetam et procédé de préparation. Download PDF

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Publication number
WO2008113901A3
WO2008113901A3 PCT/FR2008/000130 FR2008000130W WO2008113901A3 WO 2008113901 A3 WO2008113901 A3 WO 2008113901A3 FR 2008000130 W FR2008000130 W FR 2008000130W WO 2008113901 A3 WO2008113901 A3 WO 2008113901A3
Authority
WO
WIPO (PCT)
Prior art keywords
levetiracetam
controlled release
composition
preparing same
pharmaceutical composition
Prior art date
Application number
PCT/FR2008/000130
Other languages
English (en)
Other versions
WO2008113901A2 (fr
Inventor
Herve Brochart
Epouse Foucher Estelle Maurer
Original Assignee
Rd Pharmagal
Herve Brochart
Epouse Foucher Estelle Maurer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rd Pharmagal, Herve Brochart, Epouse Foucher Estelle Maurer filed Critical Rd Pharmagal
Priority to US12/525,920 priority Critical patent/US20100151018A1/en
Publication of WO2008113901A2 publication Critical patent/WO2008113901A2/fr
Publication of WO2008113901A3 publication Critical patent/WO2008113901A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention a pour objet une nouvelle formulation du lévétiracetam permettant d'obtenir une composition pharmaceutique solide, particulièrement destinée à une administration orale, à libération prolongée de lévétiracetam. L'invention a aussi pour objet un procédé de préparation d'une telle composition pharmaceutique.
PCT/FR2008/000130 2007-02-05 2008-02-05 Composition à libération prolongée de lévétiracetam et procédé de préparation. WO2008113901A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US12/525,920 US20100151018A1 (en) 2007-02-05 2008-02-05 Sustained-release levetiracetam composition and preparation process

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0700790 2007-02-05
FR0700790A FR2912056B1 (fr) 2007-02-05 2007-02-05 Composition a liberation prolongee de levetiracetam et procede de preparation

Publications (2)

Publication Number Publication Date
WO2008113901A2 WO2008113901A2 (fr) 2008-09-25
WO2008113901A3 true WO2008113901A3 (fr) 2008-11-13

Family

ID=38521035

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2008/000130 WO2008113901A2 (fr) 2007-02-05 2008-02-05 Composition à libération prolongée de lévétiracetam et procédé de préparation.

Country Status (3)

Country Link
US (1) US20100151018A1 (fr)
FR (1) FR2912056B1 (fr)
WO (1) WO2008113901A2 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010026467A2 (fr) * 2008-09-04 2010-03-11 Torrent Pharmaceuticals Ltd. Forme pharmaceutique à libération prolongée de principe actif hautement soluble
EP2179725A1 (fr) * 2008-10-23 2010-04-28 LEK Pharmaceuticals D.D. Composition pharmaceutique comprenant du lévétiracetam
EP2298290A1 (fr) 2009-09-16 2011-03-23 LEK Pharmaceuticals d.d. Composition de libération contrôlée comprenant du lévétiracetam
KR20120055313A (ko) * 2010-11-23 2012-05-31 주식회사 바이오파마티스 레베티라세탐 또는 이의 약학적으로 허용되는 염을 포함하는 용출 안정성이 개선된 서방형 약학 조성물 및 이의 제조방법
JP6440625B2 (ja) 2012-11-14 2018-12-19 ザ・ジョンズ・ホプキンス・ユニバーシティー 精神分裂病を処置するための方法および組成物
US20160030391A1 (en) * 2013-03-15 2016-02-04 The Johns Hopkins University Methods and compositions for improving cognitive function
CN105142623A (zh) 2013-03-15 2015-12-09 艾吉因生物股份有限公司 用于改善认知功能的方法和组合物
EP3827820A1 (fr) 2013-03-15 2021-06-02 The Johns Hopkins University Brivaracetam pour améliorer la fonction cognitive
EA034167B8 (ru) 2015-05-22 2021-04-27 Эйджинбайо, Инк. Фармацевтические композиции леветирацетама пролонгированного высвобождения
CN107913258A (zh) * 2016-10-09 2018-04-17 北京阜康仁生物制药科技有限公司 一种左乙拉西坦缓释片及其制备方法
JP6326114B2 (ja) * 2016-11-01 2018-05-16 エルメッド エーザイ株式会社 レベチラセタム含有医薬組成物及びその製造方法、並びにレベチラセタム含有医薬組成物の崩壊及び溶出の少なくともいずれかの遅延防止方法、及びレベチラセタム含有医薬組成物の崩壊及び溶出の少なくともいずれかの遅延防止剤

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006080029A1 (fr) * 2005-01-27 2006-08-03 Alembic Limited Formulation de lévétiracétam à libération prolongée
WO2006102750A1 (fr) * 2005-03-30 2006-10-05 Genpharm Inc. Processus a etapes combinees pour compositions pharmaceutiques
WO2006123357A2 (fr) * 2005-02-22 2006-11-23 Sun Pharmaceutical Industries Limited Composition pharmaceutique
WO2007012439A1 (fr) * 2005-07-26 2007-02-01 Ucb Pharma, S.A. Compositions pharmaceutiques a base de levetiracetam et leur methode de preparation

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006080029A1 (fr) * 2005-01-27 2006-08-03 Alembic Limited Formulation de lévétiracétam à libération prolongée
WO2006123357A2 (fr) * 2005-02-22 2006-11-23 Sun Pharmaceutical Industries Limited Composition pharmaceutique
WO2006102750A1 (fr) * 2005-03-30 2006-10-05 Genpharm Inc. Processus a etapes combinees pour compositions pharmaceutiques
WO2007012439A1 (fr) * 2005-07-26 2007-02-01 Ucb Pharma, S.A. Compositions pharmaceutiques a base de levetiracetam et leur methode de preparation

Also Published As

Publication number Publication date
US20100151018A1 (en) 2010-06-17
FR2912056B1 (fr) 2009-12-18
FR2912056A1 (fr) 2008-08-08
WO2008113901A2 (fr) 2008-09-25

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