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WO2008100559A3 - Medical devices having a micro-fluidic channeled vasculature - Google Patents

Medical devices having a micro-fluidic channeled vasculature Download PDF

Info

Publication number
WO2008100559A3
WO2008100559A3 PCT/US2008/001942 US2008001942W WO2008100559A3 WO 2008100559 A3 WO2008100559 A3 WO 2008100559A3 US 2008001942 W US2008001942 W US 2008001942W WO 2008100559 A3 WO2008100559 A3 WO 2008100559A3
Authority
WO
WIPO (PCT)
Prior art keywords
medical devices
channeled
fluidic
micro
vasculature
Prior art date
Application number
PCT/US2008/001942
Other languages
French (fr)
Other versions
WO2008100559A2 (en
Inventor
Brian K Orrick
Gary Woolf
Joseph P Vacanti
Original Assignee
Bioengine Inc
Alito Scient Inc
Gen Hospital Corp
Brian K Orrick
Gary Woolf
Joseph P Vacanti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioengine Inc, Alito Scient Inc, Gen Hospital Corp, Brian K Orrick, Gary Woolf, Joseph P Vacanti filed Critical Bioengine Inc
Publication of WO2008100559A2 publication Critical patent/WO2008100559A2/en
Publication of WO2008100559A3 publication Critical patent/WO2008100559A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/022—Artificial gland structures using bioreactors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1678—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes intracorporal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1698—Blood oxygenators with or without heat-exchangers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/18—Apparatus therefor

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Transplantation (AREA)
  • Urology & Nephrology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Emergency Medicine (AREA)
  • Water Supply & Treatment (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Chemical & Material Sciences (AREA)
  • External Artificial Organs (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The present invention provides medical devices containing a micro-fluidic channeled vasculature capable of attaining fluid and gas flow there through, which are capable of augmenting or supplanting one or more physiological functions of an organ. The medical devices may be adapted to be exogenously seeded with at least organ specific cells. Methods of making and using the medical devices to supplant or augment one or more physiological functions of an organ are also provided.
PCT/US2008/001942 2007-02-14 2008-02-14 Medical devices having a micro-fluidic channeled vasculature WO2008100559A2 (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US90153607P 2007-02-14 2007-02-14
US90139007P 2007-02-14 2007-02-14
US90158307P 2007-02-14 2007-02-14
US90158607P 2007-02-14 2007-02-14
US60/901,586 2007-02-14
US60/901,583 2007-02-14
US60/901,536 2007-02-14
US60/901,390 2007-02-14

Publications (2)

Publication Number Publication Date
WO2008100559A2 WO2008100559A2 (en) 2008-08-21
WO2008100559A3 true WO2008100559A3 (en) 2008-11-20

Family

ID=39690693

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/001942 WO2008100559A2 (en) 2007-02-14 2008-02-14 Medical devices having a micro-fluidic channeled vasculature

Country Status (1)

Country Link
WO (1) WO2008100559A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103285950A (en) * 2013-05-27 2013-09-11 苏州扬清芯片科技有限公司 Preparation method for polymer micro-fluidic chip

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8266791B2 (en) 2007-09-19 2012-09-18 The Charles Stark Draper Laboratory, Inc. Method of fabricating microfluidic structures for biomedical applications
ES2628782T3 (en) * 2009-10-29 2017-08-03 The Charles Stark Draper Laboratory, Inc Microfluidic device for blood dialysis
EP2576026A1 (en) * 2010-05-26 2013-04-10 The Charles Stark Draper Laboratory, Inc. Microfabricated artificial lung assist device, and methods of use and manufacture thereof
CN103764190B (en) 2011-06-15 2019-03-08 查尔斯斯塔克布料实验室公司 System related with the artificial cell nephron, method and apparatus
WO2016049367A1 (en) * 2014-09-24 2016-03-31 Los Alamos National Security, Llc Multi-organ media compositions and methods of their use
EP3534835A4 (en) * 2016-11-03 2020-05-13 Arizona Board of Regents on behalf of the University of Arizona Stacked tissue encapsulation device systems with or without oxygen delivery
EP3534692A4 (en) 2016-11-03 2020-06-17 Arizona Board of Regents on behalf of the University of Arizona METHODS AND SYSTEMS FOR REAL-TIME EVALUATION OF CELLS IN ENCLOSURE DEVICES BEFORE AND AFTER TRANSPLANTATION
AU2017396753B2 (en) 2016-11-03 2021-04-29 Arizona Board Of Regents On Behalf Of The University Of Arizona Stacked tissue encapsulation device systems with or without oxygen delivery
KR20190106996A (en) 2016-11-03 2019-09-18 아리조나 보드 오브 리전츠 온 비해프 오브 더 유니버시티 오브 아리조나 Encapsulation system with oxygen sensor with or without external oxygen transfer
EP3691775A1 (en) 2017-10-05 2020-08-12 Fresenius Medical Care Holdings, Inc. Polysulfone-urethane copolymer, membranes and products incorporating same, and methods for making and using same
US12115332B2 (en) 2020-10-30 2024-10-15 Arizona Board Of Regents On Behalf Of The University Of Arizona Methods and systems for encapsulation devices for housing cells and agents

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5605835A (en) * 1988-05-23 1997-02-25 Regents Of The University Of Minnesota Bioreactor device with application as a bioartificial liver
US5902745A (en) * 1995-09-22 1999-05-11 Gore Hybrid Technologies, Inc. Cell encapsulation device
US20020188240A1 (en) * 2001-05-14 2002-12-12 Gorsuch Reynolds G. Process and apparatus for utilization of in vivo extracted plasma with tissue engineering devices, bioreactors, artificial organs, and cell therapy applications
US20050084944A1 (en) * 2002-01-18 2005-04-21 Gianni Carturan Bioreactor
US20060188488A1 (en) * 2001-03-30 2006-08-24 The Arizona Board Of Regents On Behalf Of The University Of Arizona Prevascularized constructs for implantation to provide blood perfusion

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5605835A (en) * 1988-05-23 1997-02-25 Regents Of The University Of Minnesota Bioreactor device with application as a bioartificial liver
US5902745A (en) * 1995-09-22 1999-05-11 Gore Hybrid Technologies, Inc. Cell encapsulation device
US20060188488A1 (en) * 2001-03-30 2006-08-24 The Arizona Board Of Regents On Behalf Of The University Of Arizona Prevascularized constructs for implantation to provide blood perfusion
US20020188240A1 (en) * 2001-05-14 2002-12-12 Gorsuch Reynolds G. Process and apparatus for utilization of in vivo extracted plasma with tissue engineering devices, bioreactors, artificial organs, and cell therapy applications
US20050084944A1 (en) * 2002-01-18 2005-04-21 Gianni Carturan Bioreactor

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103285950A (en) * 2013-05-27 2013-09-11 苏州扬清芯片科技有限公司 Preparation method for polymer micro-fluidic chip

Also Published As

Publication number Publication date
WO2008100559A2 (en) 2008-08-21

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