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WO2008100142A3 - Formulation vaccinale - Google Patents

Formulation vaccinale Download PDF

Info

Publication number
WO2008100142A3
WO2008100142A3 PCT/NL2008/050079 NL2008050079W WO2008100142A3 WO 2008100142 A3 WO2008100142 A3 WO 2008100142A3 NL 2008050079 W NL2008050079 W NL 2008050079W WO 2008100142 A3 WO2008100142 A3 WO 2008100142A3
Authority
WO
WIPO (PCT)
Prior art keywords
vaccine formulation
hydrogel
entrapped antigen
vaccine
subject
Prior art date
Application number
PCT/NL2008/050079
Other languages
English (en)
Other versions
WO2008100142A2 (fr
Inventor
Sebastianus Hermanus Adrianus Kremer
Rudolf Verrijk
Der Raad-Meijer Yvette Jacqueline Van
Original Assignee
Octoplus Sciences Bv
Sebastianus Hermanus Adrianus Kremer
Rudolf Verrijk
Der Raad-Meijer Yvette Jacqueline Van
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP07008366A external-priority patent/EP1985284A1/fr
Application filed by Octoplus Sciences Bv, Sebastianus Hermanus Adrianus Kremer, Rudolf Verrijk, Der Raad-Meijer Yvette Jacqueline Van filed Critical Octoplus Sciences Bv
Publication of WO2008100142A2 publication Critical patent/WO2008100142A2/fr
Publication of WO2008100142A3 publication Critical patent/WO2008100142A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/29—Hepatitis virus
    • A61K39/292—Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)

Abstract

La présente invention concerne une nouvelle formulation vaccinale comprenant un antigène encapsulé dans un hydrogel. Ce type d'antigène encapsulé dans un hydrogel peut être avantageusement utilisé dans la préparation d'une formulation vaccinale qui peut remplacer les protocoles habituels de vaccination en plusieurs injections. Ce type de formulation vaccinale fournit avantageusement un protocole de primo-vaccination et de rappel en une seule injection. L'invention concerne également une méthode pour immuniser un sujet qui en a besoin comprenant l'administration audit sujet dudit antigène encapsulé dans de l'hydrogel ou ce type de formulation vaccinale comprenant l'antigène encapsulé dans un hydrogel.
PCT/NL2008/050079 2007-02-12 2008-02-12 Formulation vaccinale WO2008100142A2 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP07002907.9 2007-02-12
EP07002907 2007-02-12
EP07008366.2 2007-04-25
EP07008366A EP1985284A1 (fr) 2007-04-25 2007-04-25 Formule de vaccin

Publications (2)

Publication Number Publication Date
WO2008100142A2 WO2008100142A2 (fr) 2008-08-21
WO2008100142A3 true WO2008100142A3 (fr) 2008-10-30

Family

ID=39682665

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/NL2008/050079 WO2008100142A2 (fr) 2007-02-12 2008-02-12 Formulation vaccinale

Country Status (1)

Country Link
WO (1) WO2008100142A2 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995002416A1 (fr) * 1993-07-12 1995-01-26 Virus Research Institute Vaccins microencapsules sur une base d'hydrogel
WO1998000170A1 (fr) * 1996-07-01 1998-01-08 Universiteit Utrecht Hydrogels hydrolysables pour liberation controlee
US20020076441A1 (en) * 2000-04-27 2002-06-20 Macromed, Inc. Bioactive agent delivering system comprised of microparticles within a biodegradable to improve release profiles

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995002416A1 (fr) * 1993-07-12 1995-01-26 Virus Research Institute Vaccins microencapsules sur une base d'hydrogel
WO1998000170A1 (fr) * 1996-07-01 1998-01-08 Universiteit Utrecht Hydrogels hydrolysables pour liberation controlee
US20020076441A1 (en) * 2000-04-27 2002-06-20 Macromed, Inc. Bioactive agent delivering system comprised of microparticles within a biodegradable to improve release profiles

Also Published As

Publication number Publication date
WO2008100142A2 (fr) 2008-08-21

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