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WO2008155998A1 - Agent tranquillisant/antidépresseur - Google Patents

Agent tranquillisant/antidépresseur Download PDF

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Publication number
WO2008155998A1
WO2008155998A1 PCT/JP2008/060477 JP2008060477W WO2008155998A1 WO 2008155998 A1 WO2008155998 A1 WO 2008155998A1 JP 2008060477 W JP2008060477 W JP 2008060477W WO 2008155998 A1 WO2008155998 A1 WO 2008155998A1
Authority
WO
WIPO (PCT)
Prior art keywords
antianxiety
antidepressant
antidepressant agent
activity
agent
Prior art date
Application number
PCT/JP2008/060477
Other languages
English (en)
Japanese (ja)
Inventor
Eiji Takeda
Junji Terao
Hiroyoshi Sei
Hiroyuki Sakakibara
Kazuyoshi Kitaoka
Toshitsugu Miyazaki
Chieko Kitajima
Original Assignee
Nagase & Co., Ltd.
The University Of Tokushima
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nagase & Co., Ltd., The University Of Tokushima filed Critical Nagase & Co., Ltd.
Priority to JP2009520423A priority Critical patent/JPWO2008155998A1/ja
Publication of WO2008155998A1 publication Critical patent/WO2008155998A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Psychiatry (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Pain & Pain Management (AREA)
  • Mycology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Fodder In General (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

La présente invention concerne : un agent tranquillisant/antidépresseur ayant un niveau satisfaisant d'activité tranquillisante et/ou d'activité antidépressive ; et un aliment ou une boisson comprenant l'agent tranquillisant/antidépresseur. L'invention concerne spécifiquement un agent tranquillisant/antidépresseur comprenant un extrait de ginseng fermenté et/ou un composant produit à partir de l'extrait de ginseng fermenté comme ingrédient actif. L'invention concerne également spécifiquement un aliment ou une boisson portant une notice mentionnant que cet aliment/boisson est utilisé(e) pour la prévention ou le traitement de l'anxiété ou de la dépression, qui est caractérisé par le fait qu'il(elle) comprend un agent tranquillisant/antidépresseur et présente une activité tranquillisante/antidépressive.
PCT/JP2008/060477 2007-06-21 2008-06-06 Agent tranquillisant/antidépresseur WO2008155998A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2009520423A JPWO2008155998A1 (ja) 2007-06-21 2008-06-06 抗不安抗うつ剤

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2007164183 2007-06-21
JP2007164034 2007-06-21
JP2007-164183 2007-06-21
JP2007-164034 2007-06-21

Publications (1)

Publication Number Publication Date
WO2008155998A1 true WO2008155998A1 (fr) 2008-12-24

Family

ID=40156157

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/060477 WO2008155998A1 (fr) 2007-06-21 2008-06-06 Agent tranquillisant/antidépresseur

Country Status (2)

Country Link
JP (1) JPWO2008155998A1 (fr)
WO (1) WO2008155998A1 (fr)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011121926A (ja) * 2009-12-14 2011-06-23 Lion Corp プロトパナキサトリオール及びプロトパナキサジオール含有組成物
CN102145006A (zh) * 2010-02-09 2011-08-10 张作光 人参皂甙Ppt的抗抑郁用途
JP2013529899A (ja) * 2010-05-14 2013-07-25 株式会社ジーシーエイチアンドピー ジンセノサイド成分を増加させた新規な加工人参または加工人参抽出物の製造方法
JP2015168614A (ja) * 2014-03-04 2015-09-28 長瀬産業株式会社 Ｇｌｐ−１分泌促進剤
JP2016508489A (ja) * 2013-01-31 2016-03-22 シャンハイ イノベーティブ リサーチ センター オブ トラディショナル チャイニーズ メディスン プロトパナキサジオール誘導体、その製造方法及びその応用
KR101641509B1 (ko) * 2015-01-22 2016-07-21 샘표 주식회사 아글리콘인 ppd 및/또는 ppt를 유효성분으로 포함하는 항스트레스용 조성물
JP6450878B1 (ja) * 2018-03-28 2019-01-09 株式会社ナガセビューティケァ 発酵物の製造方法
JP2019524835A (ja) * 2016-08-16 2019-09-05 エムディー ヘルスケア インコーポレイテッドＭｄ Ｈｅａｌｔｈｃａｒｅ Ｉｎｃ． ラクトバチルス属細菌由来小胞を含む精神疾患の予防または治療用組成物
US10709749B2 (en) 2013-08-30 2020-07-14 Green Cross Wellbeing Corporation Composition for preventing and treating cancer-related fatigue, containing processed ginseng powder or processed ginseng extract having increased ginsenoside constituent

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1099094A (ja) * 1996-09-25 1998-04-21 Happy World:Kk 薬用ニンジンサポニン代謝産物の製造法
JP2004049154A (ja) * 2002-07-23 2004-02-19 Hideo Hasegawa サポニン分解物を含む発酵人参およびその製造方法
JP2005160373A (ja) * 2003-12-02 2005-06-23 Hideo Hasegawa 配糖体分解性プロバイオティクス
JP2006508660A (ja) * 2002-12-05 2006-03-16 ホングリム トレーディング カンパニー リミテッド 人参の乳酸菌発酵物、それを含有する人参ヨーグルト及びそれに利用される乳酸菌の菌株
JP2008000102A (ja) * 2006-06-26 2008-01-10 Bio Ken:Kk ヨーグルト製造用種菌

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4773512B2 (ja) * 2005-04-26 2011-09-14 コ，ブン−キョン 人参サポニンＲｇ２の抽出方法及びその抽出物を含む医薬組成物とその用途
CN100438876C (zh) * 2006-06-09 2008-12-03 上海中药创新研究中心 20(s)-原人参二醇在制备抗抑郁药物中的应用

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1099094A (ja) * 1996-09-25 1998-04-21 Happy World:Kk 薬用ニンジンサポニン代謝産物の製造法
JP2004049154A (ja) * 2002-07-23 2004-02-19 Hideo Hasegawa サポニン分解物を含む発酵人参およびその製造方法
JP2006508660A (ja) * 2002-12-05 2006-03-16 ホングリム トレーディング カンパニー リミテッド 人参の乳酸菌発酵物、それを含有する人参ヨーグルト及びそれに利用される乳酸菌の菌株
JP2005160373A (ja) * 2003-12-02 2005-06-23 Hideo Hasegawa 配糖体分解性プロバイオティクス
JP2008000102A (ja) * 2006-06-26 2008-01-10 Bio Ken:Kk ヨーグルト製造用種菌

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
HASEGAWA H.: "Kanpo to Probiotic", IGAKU NO AYUMI, vol. 207, no. 10, 2003, pages 857 - 861 *
PARK J.-H. ET AL.: "Anxiolytic-like effects of ginseng in the elevated plus-maze model: Comparison of red dinseng and sun ginseng", PROGRESS IN NEURO-PSYCHOPHARMACOLOGY AND BIOLOGICAL PSYCHIATRY, vol. 29, no. 6, July 2005 (2005-07-01), pages 895 - 900 *
TACHIKAWA E. ET AL.: "In vitro inhibition of adrenal catecholamine secretion by steroidal metabolites of ginseng saponins", BIOCHEMICAL PHARMACOLOGY, vol. 66, no. 11, 2003, pages 2213 - 2221 *
WEI X.-Y. ET AL.: "Anxiolytic effect of saponins from Panax quinquefolium in mice", J. ETHNOPHARMACOL., vol. 111, no. 3, 22 May 2007 (2007-05-22), pages 613 - 618 *

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011121926A (ja) * 2009-12-14 2011-06-23 Lion Corp プロトパナキサトリオール及びプロトパナキサジオール含有組成物
CN102145006A (zh) * 2010-02-09 2011-08-10 张作光 人参皂甙Ppt的抗抑郁用途
JP2013529899A (ja) * 2010-05-14 2013-07-25 株式会社ジーシーエイチアンドピー ジンセノサイド成分を増加させた新規な加工人参または加工人参抽出物の製造方法
US9512453B2 (en) 2010-05-14 2016-12-06 Green Cross Wellbeing Corporation Method for preparing novel processed ginseng or an extract thereof, the usually minute ginsenoside content of which is increased
JP2016508489A (ja) * 2013-01-31 2016-03-22 シャンハイ イノベーティブ リサーチ センター オブ トラディショナル チャイニーズ メディスン プロトパナキサジオール誘導体、その製造方法及びその応用
US10709749B2 (en) 2013-08-30 2020-07-14 Green Cross Wellbeing Corporation Composition for preventing and treating cancer-related fatigue, containing processed ginseng powder or processed ginseng extract having increased ginsenoside constituent
US11464821B2 (en) 2013-08-30 2022-10-11 Green Cross Wellbeing Corporation Composition for reducing cancer cachexia or weight loss caused by anticancer drug therapy or radiation therapy comprising ginseng extract having increased ginsenoside Rg3 and Rh2
JP2015168614A (ja) * 2014-03-04 2015-09-28 長瀬産業株式会社 Ｇｌｐ−１分泌促進剤
KR101641509B1 (ko) * 2015-01-22 2016-07-21 샘표 주식회사 아글리콘인 ppd 및/또는 ppt를 유효성분으로 포함하는 항스트레스용 조성물
JP2019524835A (ja) * 2016-08-16 2019-09-05 エムディー ヘルスケア インコーポレイテッドＭｄ Ｈｅａｌｔｈｃａｒｅ Ｉｎｃ． ラクトバチルス属細菌由来小胞を含む精神疾患の予防または治療用組成物
EP3501527A4 (fr) * 2016-08-16 2020-05-06 MD Healthcare Inc. Composition permettant de prévenir ou de traiter un trouble mental, contenant une vésicule dérivée de bactéries d'une espècelactobacillus
US11583559B2 (en) 2016-08-16 2023-02-21 Md Healthcare Inc. Composition for preventing or treating mental disorder, containing Lactobacillus sp. bacteria-derived vesicle
JP2019170246A (ja) * 2018-03-28 2019-10-10 株式会社ナガセビューティケァ 発酵物の製造方法
JP6450878B1 (ja) * 2018-03-28 2019-01-09 株式会社ナガセビューティケァ 発酵物の製造方法

Also Published As

Publication number Publication date
JPWO2008155998A1 (ja) 2010-08-26

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