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WO2008035380A3 - An improved process for the preparation of high purity formoterol and its pharmaceutically acceptable salts - Google Patents

An improved process for the preparation of high purity formoterol and its pharmaceutically acceptable salts Download PDF

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Publication number
WO2008035380A3
WO2008035380A3 PCT/IN2007/000415 IN2007000415W WO2008035380A3 WO 2008035380 A3 WO2008035380 A3 WO 2008035380A3 IN 2007000415 W IN2007000415 W IN 2007000415W WO 2008035380 A3 WO2008035380 A3 WO 2008035380A3
Authority
WO
WIPO (PCT)
Prior art keywords
formoterol
preparation
pharmaceutically acceptable
acceptable salts
high purity
Prior art date
Application number
PCT/IN2007/000415
Other languages
French (fr)
Other versions
WO2008035380A2 (en
Inventor
Srinivasa Krishna Murt Konduri
Kali Satya Bhujanga Adibhatla
Reddy Muddasani Pulla
Ravi Kumar Remella
Venkaiah Chowdary Nannapaneni
Original Assignee
Natco Pharma Ltd
Srinivasa Krishna Murt Konduri
Kali Satya Bhujanga Adibhatla
Reddy Muddasani Pulla
Ravi Kumar Remella
Venkaiah Chowdary Nannapaneni
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Natco Pharma Ltd, Srinivasa Krishna Murt Konduri, Kali Satya Bhujanga Adibhatla, Reddy Muddasani Pulla, Ravi Kumar Remella, Venkaiah Chowdary Nannapaneni filed Critical Natco Pharma Ltd
Publication of WO2008035380A2 publication Critical patent/WO2008035380A2/en
Publication of WO2008035380A3 publication Critical patent/WO2008035380A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to an improved process for the preparation of high purity formoterol and its pharmaceutically acceptable salts of Formula-I(C).
PCT/IN2007/000415 2006-09-19 2007-09-17 An improved process for the preparation of high purity formoterol and its pharmaceutically acceptable salts WO2008035380A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1713CH2006 2006-09-19
IN1713/CHE/2006 2006-09-19

Publications (2)

Publication Number Publication Date
WO2008035380A2 WO2008035380A2 (en) 2008-03-27
WO2008035380A3 true WO2008035380A3 (en) 2008-05-08

Family

ID=39111337

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2007/000415 WO2008035380A2 (en) 2006-09-19 2007-09-17 An improved process for the preparation of high purity formoterol and its pharmaceutically acceptable salts

Country Status (1)

Country Link
WO (1) WO2008035380A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011523658A (en) * 2008-06-02 2011-08-18 シプラ・リミテッド Synthetic method of alformoterol
WO2010128355A2 (en) 2008-12-26 2010-11-11 Actavis Group Ptc Ehf Improved processes for preparing substantially pure arformoterol and its intermediates
CN101921208B (en) * 2009-06-15 2013-08-14 上海医药工业研究院 Preparation method of formoterol intermediate
CN104220420B (en) 2012-03-12 2016-08-31 利斯维实验室有限公司 A kind of New Polycrystalline of long-acting beta-2-adrenoceptor agonist
CN103864627B (en) * 2012-12-12 2017-07-28 天津金耀集团有限公司 The method for splitting of formoterol chiral intermediate
CN103896795B (en) * 2012-12-26 2016-01-06 上海医药工业研究院 The preparation method and its usage of benzamide compound, its intermediate
CN106518690A (en) * 2016-09-21 2017-03-22 北京万全德众医药生物技术有限公司 Preparation method of arformoterol tartrate important intermediate
CN113999134B (en) * 2018-11-28 2024-11-05 广州呼吸药物工程技术有限公司 A method for preparing formoterol, its pharmaceutically acceptable salt and its intermediates
CN115368250B (en) * 2022-09-02 2024-07-26 博诺康源(北京)药业科技有限公司 Method for resolution of formoterol chiral intermediate

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3994974A (en) * 1972-02-05 1976-11-30 Yamanouchi Pharmaceutical Co., Ltd. α-Aminomethylbenzyl alcohol derivatives
WO1992005147A1 (en) * 1990-09-26 1992-04-02 Aktiebolaget Astra New process for preparing formoterol and related compounds
WO1999067198A1 (en) * 1998-06-23 1999-12-29 Sepracor Inc. Desformoterol and process for its preparation

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3994974A (en) * 1972-02-05 1976-11-30 Yamanouchi Pharmaceutical Co., Ltd. α-Aminomethylbenzyl alcohol derivatives
WO1992005147A1 (en) * 1990-09-26 1992-04-02 Aktiebolaget Astra New process for preparing formoterol and related compounds
WO1999067198A1 (en) * 1998-06-23 1999-12-29 Sepracor Inc. Desformoterol and process for its preparation

Also Published As

Publication number Publication date
WO2008035380A2 (en) 2008-03-27

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