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WO2008017598A3 - Citrusal aroma receptors and use of myrac aldehyde derivatives for increasing the flagellation frequency of a spermatozoon - Google Patents

Citrusal aroma receptors and use of myrac aldehyde derivatives for increasing the flagellation frequency of a spermatozoon Download PDF

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Publication number
WO2008017598A3
WO2008017598A3 PCT/EP2007/057801 EP2007057801W WO2008017598A3 WO 2008017598 A3 WO2008017598 A3 WO 2008017598A3 EP 2007057801 W EP2007057801 W EP 2007057801W WO 2008017598 A3 WO2008017598 A3 WO 2008017598A3
Authority
WO
WIPO (PCT)
Prior art keywords
citrusal
flagellation
spermatozoon
increasing
frequency
Prior art date
Application number
PCT/EP2007/057801
Other languages
German (de)
French (fr)
Other versions
WO2008017598A2 (en
Inventor
Hanns Hatt
Original Assignee
Symrise Gmbh & Co Kg
Hanns Hatt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Symrise Gmbh & Co Kg, Hanns Hatt filed Critical Symrise Gmbh & Co Kg
Publication of WO2008017598A2 publication Critical patent/WO2008017598A2/en
Publication of WO2008017598A3 publication Critical patent/WO2008017598A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/11—Aldehydes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • G01N33/567—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds utilising isolate of tissue or organ as binding agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/36—Gynecology or obstetrics
    • G01N2800/367—Infertility, e.g. sperm disorder, ovulatory dysfunction

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Reproductive Health (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Pregnancy & Childbirth (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)

Abstract

The invention relates to the field of olfactory receptors, conception-related medication, and biosensors.
PCT/EP2007/057801 2006-08-11 2007-07-27 Citrusal aroma receptors and use of myrac aldehyde derivatives for increasing the flagellation frequency of a spermatozoon WO2008017598A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102006037581.5 2006-08-11
DE102006037581A DE102006037581A1 (en) 2006-08-11 2006-08-11 Citrusal perfume receptors

Publications (2)

Publication Number Publication Date
WO2008017598A2 WO2008017598A2 (en) 2008-02-14
WO2008017598A3 true WO2008017598A3 (en) 2009-01-15

Family

ID=38819615

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2007/057801 WO2008017598A2 (en) 2006-08-11 2007-07-27 Citrusal aroma receptors and use of myrac aldehyde derivatives for increasing the flagellation frequency of a spermatozoon

Country Status (2)

Country Link
DE (1) DE102006037581A1 (en)
WO (1) WO2008017598A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2017001220A (en) 2014-07-30 2017-10-02 Georgia Pacific Consumer Products Lp Air freshener dispensers, cartridges therefor, systems, and methods.

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55130914A (en) * 1979-03-30 1980-10-11 Hisamitsu Pharmaceut Co Inc Novel antiallergic agent
JPS55133311A (en) * 1979-04-05 1980-10-17 Hisamitsu Pharmaceut Co Inc Novel antiallergic agent
WO2000001358A1 (en) * 1998-07-07 2000-01-13 Quest International B.V. Method of reducing or preventing malodour
WO2001027158A2 (en) * 1999-10-08 2001-04-19 Digiscents Olfactory receptor sequences

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55130914A (en) * 1979-03-30 1980-10-11 Hisamitsu Pharmaceut Co Inc Novel antiallergic agent
JPS55133311A (en) * 1979-04-05 1980-10-17 Hisamitsu Pharmaceut Co Inc Novel antiallergic agent
WO2000001358A1 (en) * 1998-07-07 2000-01-13 Quest International B.V. Method of reducing or preventing malodour
WO2001027158A2 (en) * 1999-10-08 2001-04-19 Digiscents Olfactory receptor sequences

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; "Novel allergy inhibitors", XP002492219, retrieved from STN Database accession no. 1981:52981 *
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; "Novel pharmaceuticals containing allergy inhibitors", XP002492218, retrieved from STN Database accession no. 1981:71517 *
DATABASE WPI Week 198019, 11 October 1980 Derwent World Patents Index; Class 804, Page 7, AN 1980-83629C, XP002492221, HIRANO M; IDE H; NAKAGAWA A; NAKAJIMA Y; NODA K; YAMAGATA K; YATANI T: "Antiallergic agent contg. cyclohexene deriv. - for treating rheumatoid arthritis, asthma, nephritis etc., for oral or parental administration" *
DATABASE WPI Week 198019, 17 October 1980 Derwent World Patents Index; Class 804, Page 8, AN 1980-85220c, XP002492220, HIRANO M; IDE H; NAKAGAWA A; NAKAJIMA Y; NODA K; YAMAGATA K; YATANI T: "Anti-allergic agent - comprising cyclohexene deriv. as active component" *
SPEHR ET AL: "Odorant receptors and olfactory-like signaling mechanisms in mammalian sperm", MOLECULAR AND CELLULAR ENDOCRINOLOGY, AMSTERDAM, vol. 250, no. 1-2, 16 May 2006 (2006-05-16), pages 128 - 136, XP005434349, ISSN: 0303-7207 *
TOUHARA K ET AL: "Functional identification and reconstitution of an odorant receptor in single olfactory neurons", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, vol. 96, no. 7, 1 January 1999 (1999-01-01), pages 4040 - 4045, XP002973354, ISSN: 0027-8424 *

Also Published As

Publication number Publication date
WO2008017598A2 (en) 2008-02-14
DE102006037581A1 (en) 2008-02-14

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