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WO2008007322A3 - Anti-hemorrhage medication pack - Google Patents

Anti-hemorrhage medication pack Download PDF

Info

Publication number
WO2008007322A3
WO2008007322A3 PCT/IB2007/052661 IB2007052661W WO2008007322A3 WO 2008007322 A3 WO2008007322 A3 WO 2008007322A3 IB 2007052661 W IB2007052661 W IB 2007052661W WO 2008007322 A3 WO2008007322 A3 WO 2008007322A3
Authority
WO
WIPO (PCT)
Prior art keywords
hemorrhage
analogues
fragments
drug
medication pack
Prior art date
Application number
PCT/IB2007/052661
Other languages
French (fr)
Other versions
WO2008007322A2 (en
Inventor
Giorgio Noera
Alfio Bertolini
Original Assignee
Health Ricerca E Sviluppo S R
Giorgio Noera
Alfio Bertolini
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Health Ricerca E Sviluppo S R, Giorgio Noera, Alfio Bertolini filed Critical Health Ricerca E Sviluppo S R
Priority to CA2657370A priority Critical patent/CA2657370C/en
Priority to US12/373,174 priority patent/US8318673B2/en
Publication of WO2008007322A2 publication Critical patent/WO2008007322A2/en
Publication of WO2008007322A3 publication Critical patent/WO2008007322A3/en
Priority to IL196443A priority patent/IL196443A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • A61K38/35—Corticotropin [ACTH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2046—Media being expelled from injector by gas generation, e.g. explosive charge
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/206—With automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3103—Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle
    • A61M2005/3104—Caps for syringes without needle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2455—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened
    • A61M5/2466—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened by piercing without internal pressure increase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

An anti-hemorrhage medication pack for administering an anti-hemorrhage drug, in particular for the treatment of hemorrhage caused by trauma in emergency situations comprises an active ingredient selected from the group comprising the 1- 24 amino acid sequence of the adrenocorticotropic hormone (ACTH 1-24) and all its fragments and analogues, and analogues of fragments, with agonist activity on the MC4 melanocortin receptors, and all the synthesis agonists, including those with a non-peptidic structure, of the MC4 melanocortin receptors, and an auto-injector (1; 11 ) for automatically injecting a patient with said drug.
PCT/IB2007/052661 2006-07-10 2007-07-06 Anti-hemorrhage medication pack WO2008007322A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CA2657370A CA2657370C (en) 2006-07-10 2007-07-06 Anti-hemorrhage medication pack
US12/373,174 US8318673B2 (en) 2006-07-10 2007-07-06 Anti-hemorrhage medication pack
IL196443A IL196443A (en) 2006-07-10 2009-01-11 Anti-hemorrhage medication pack

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000222A ITMO20060222A1 (en) 2006-07-10 2006-07-10 ANTIEMORRAGIC MEDICATION PACKAGE
ITMO2006A000222 2006-07-10

Publications (2)

Publication Number Publication Date
WO2008007322A2 WO2008007322A2 (en) 2008-01-17
WO2008007322A3 true WO2008007322A3 (en) 2008-05-02

Family

ID=38464800

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2007/052661 WO2008007322A2 (en) 2006-07-10 2007-07-06 Anti-hemorrhage medication pack

Country Status (6)

Country Link
US (1) US8318673B2 (en)
EP (1) EP1878454B1 (en)
CA (1) CA2657370C (en)
IL (1) IL196443A (en)
IT (1) ITMO20060222A1 (en)
WO (1) WO2008007322A2 (en)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2475573C (en) 2002-02-11 2013-03-26 Antares Pharma, Inc. Intradermal injector
US7648483B2 (en) 2004-11-22 2010-01-19 Intelliject, Inc. Devices, systems and methods for medicament delivery
CN101087625B (en) 2004-11-22 2012-02-22 因特利杰克特有限公司 Devices and systems for medicament delivery
US10737028B2 (en) 2004-11-22 2020-08-11 Kaleo, Inc. Devices, systems and methods for medicament delivery
US7947017B2 (en) 2004-11-22 2011-05-24 Intelliject, Inc. Devices, systems and methods for medicament delivery
US11590286B2 (en) 2004-11-22 2023-02-28 Kaleo, Inc. Devices, systems and methods for medicament delivery
JP5216328B2 (en) 2005-01-24 2013-06-19 アンタレス ファーマ インコーポレイテッド Pre-filled needle assist syringe jet injector
PL2058020T3 (en) 2005-02-01 2013-03-29 Kaleo Inc Devices for medicament delivery
WO2007131013A1 (en) 2006-05-03 2007-11-15 Antares Pharma, Inc. Two-stage reconstituting injector
WO2007131025A1 (en) 2006-05-03 2007-11-15 Antares Pharma, Inc. Injector with adjustable dosing
WO2009114542A1 (en) 2008-03-10 2009-09-17 Antares Pharma, Inc. Injector safety device
AU2009279719B2 (en) 2008-08-05 2015-07-23 Antares Pharma, Inc. Multiple dosage injector
US8579865B2 (en) 2009-03-20 2013-11-12 Antares Pharma, Inc. Hazardous agent injection system
US9084849B2 (en) 2011-01-26 2015-07-21 Kaleo, Inc. Medicament delivery devices for administration of a medicament within a prefilled syringe
US8627816B2 (en) 2011-02-28 2014-01-14 Intelliject, Inc. Medicament delivery device for administration of opioid antagonists including formulations for naloxone
US8939943B2 (en) 2011-01-26 2015-01-27 Kaleo, Inc. Medicament delivery device for administration of opioid antagonists including formulations for naloxone
US9220660B2 (en) 2011-07-15 2015-12-29 Antares Pharma, Inc. Liquid-transfer adapter beveled spike
US8496619B2 (en) 2011-07-15 2013-07-30 Antares Pharma, Inc. Injection device with cammed ram assembly
KR20150003179A (en) 2012-03-06 2015-01-08 안타레스 팔마, 인코퍼레이티드 Prefilled syringe with breakaway force feature
KR20150011346A (en) 2012-04-06 2015-01-30 안타레스 팔마, 인코퍼레이티드 Needle assisted jet injection administration of testosterone compositions
US9364610B2 (en) 2012-05-07 2016-06-14 Antares Pharma, Inc. Injection device with cammed ram assembly
PT3659647T (en) 2013-02-11 2024-03-27 Antares Pharma Inc NEEDLE-ASSISTED JET INJECTION DEVICE HAVING REDUCED TRIGGER FORCE
JP6030803B2 (en) 2013-03-11 2016-11-24 アンタレス・ファーマ・インコーポレーテッド Dose syringe with pinion system
WO2014165136A1 (en) 2013-03-12 2014-10-09 Antares Pharma, Inc. Constant volume prefilled syringes and kits thereof
ZA201407536B (en) 2013-10-21 2017-09-27 Ems Sa Parenteral pharmaceutical composition containing cosyntropin
US9517307B2 (en) 2014-07-18 2016-12-13 Kaleo, Inc. Devices and methods for delivering opioid antagonists including formulations for naloxone
US10004700B1 (en) * 2017-05-16 2018-06-26 Jugal K. Taneja More potent and less toxic formulations of epinephrine and methods of medical use
EP3316928B1 (en) 2015-06-30 2022-10-19 Kaleo, Inc. Auto-injectors for administration of a medicament within a prefilled syringe
JP7014797B2 (en) 2016-12-23 2022-02-01 カレオ，インコーポレイテッド Drug delivery devices and methods for delivering drugs to babies and children
US11266611B2 (en) 2017-05-16 2022-03-08 Eton Pharmaceuticals, Inc. More potent and less toxic formulations of epinephrine and methods of medical use
AU2020331302A1 (en) 2019-08-09 2022-01-06 Kaleo, Inc. Devices and methods for delivery of substances within a prefilled syringe
US12268847B1 (en) 2021-02-10 2025-04-08 Kaleo, Inc. Devices and methods for delivery of substances within a medicament container

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5380710A (en) * 1985-08-30 1995-01-10 Bertolini; Alfio Pharmaceutical compositions containing ACTH (1-24) for the therapy of shock conditions and respiratory and cardiocirculatory insufficiences
WO2000029050A1 (en) * 1998-11-14 2000-05-25 Castellano Thomas P Improved gas power source for a needle-less injector
US6406455B1 (en) * 1998-12-18 2002-06-18 Biovalve Technologies, Inc. Injection devices
US20030036725A1 (en) * 2000-09-21 2003-02-20 Gilad Lavi Reconstitution and injection system
GB2388033A (en) * 2002-05-02 2003-11-05 Pa Consulting Services Automatic injection device

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002519356A (en) * 1998-06-26 2002-07-02 ファイザー・プロダクツ・インク Improved process for the preparation of Schiff base adducts of o-hydroxyaldehydes and amines, and composition of substances based thereon
US6387078B1 (en) * 2000-12-21 2002-05-14 Gillespie, Iii Richard D. Automatic mixing and injecting apparatus
US7959600B2 (en) * 2004-12-30 2011-06-14 Byeong S. Chang Container closure delivery system

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5380710A (en) * 1985-08-30 1995-01-10 Bertolini; Alfio Pharmaceutical compositions containing ACTH (1-24) for the therapy of shock conditions and respiratory and cardiocirculatory insufficiences
WO2000029050A1 (en) * 1998-11-14 2000-05-25 Castellano Thomas P Improved gas power source for a needle-less injector
US6406455B1 (en) * 1998-12-18 2002-06-18 Biovalve Technologies, Inc. Injection devices
US20030036725A1 (en) * 2000-09-21 2003-02-20 Gilad Lavi Reconstitution and injection system
GB2388033A (en) * 2002-05-02 2003-11-05 Pa Consulting Services Automatic injection device

Also Published As

Publication number Publication date
US8318673B2 (en) 2012-11-27
EP1878454A1 (en) 2008-01-16
IL196443A (en) 2014-03-31
CA2657370A1 (en) 2008-01-17
EP1878454B1 (en) 2019-04-24
CA2657370C (en) 2016-03-01
WO2008007322A2 (en) 2008-01-17
EP1878454A9 (en) 2009-03-25
IL196443A0 (en) 2009-11-18
US20090318361A1 (en) 2009-12-24
ITMO20060222A1 (en) 2008-01-11

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