WO2008050185A3 - Nouveaux polymorphes de la périndopril erbumine - Google Patents
Nouveaux polymorphes de la périndopril erbumine Download PDFInfo
- Publication number
- WO2008050185A3 WO2008050185A3 PCT/IB2007/000364 IB2007000364W WO2008050185A3 WO 2008050185 A3 WO2008050185 A3 WO 2008050185A3 IB 2007000364 W IB2007000364 W IB 2007000364W WO 2008050185 A3 WO2008050185 A3 WO 2008050185A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- perindopril erbumine
- novel polymorphs
- disclosed
- novel
- polymorphs
- Prior art date
Links
- 229960003929 perindopril erbumine Drugs 0.000 title abstract 2
- IYNMDWMQHSMDDE-MHXJNQAMSA-N perindopril erbumine Chemical compound CC(C)(C)N.C1CCC[C@@H]2N(C(=O)[C@H](C)N[C@@H](CCC)C(=O)OCC)[C@H](C(O)=O)C[C@@H]21 IYNMDWMQHSMDDE-MHXJNQAMSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
L'invention concerne un nouveau polymorphe stable de la périndopril erbumine, appelé polymorphe de Forme Thêta (θ). L'invention porte également sur un procédé permettant de le préparer et sur les compositions pharmaceutiques le contenant.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN1769/MUM/2006 | 2006-10-26 | ||
IN1769MU2006 | 2006-10-26 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2008050185A2 WO2008050185A2 (fr) | 2008-05-02 |
WO2008050185A3 true WO2008050185A3 (fr) | 2011-04-07 |
Family
ID=39324967
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IB2007/000364 WO2008050185A2 (fr) | 2006-10-26 | 2007-02-16 | Nouveaux polymorphes de la périndopril erbumine |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2008050185A2 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112697935B (zh) * | 2020-12-10 | 2021-09-28 | 湖南泰新医药科技有限公司 | 同时测定人血浆中培哚普利和培哚普利拉浓度的方法 |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT105315B (pt) | 2010-09-29 | 2013-01-16 | Inst Superior Tecnico | Uma nova forma cristalina hidratada de erbumina de perindopril, métodos para a sua preparação e sua utilização em preparações farmacêuticas |
CN103822996A (zh) * | 2014-03-20 | 2014-05-28 | 东英(江苏)药业有限公司 | 一种培哚普利叔丁胺盐含量的测定方法 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001087836A1 (fr) * | 2000-07-06 | 2001-11-22 | Les Laboratoires Servier | Nouvelle forme cristalline $g(b) du sel de tert-butylamine du perindopril, son procede de preparation, et les compositions pharmaceutiques qui la contiennent |
WO2004113293A1 (fr) * | 2003-06-24 | 2004-12-29 | Les Laboratoires Servier | Nouvelles formes cristallines de perindopril erbumine |
WO2005037788A1 (fr) * | 2003-10-21 | 2005-04-28 | Lupin Ltd. | Nouvelle methode de preparation de perindopril erbumine cristalline |
WO2005068425A1 (fr) * | 2004-01-14 | 2005-07-28 | Lek Pharmaceuticals D.D. | Nouvelle forme cristalline de perindopril |
JP2006169169A (ja) * | 2004-12-16 | 2006-06-29 | Permachem Asia Ltd | ペリンドプリルエルブミンのi型結晶、及びその製造方法 |
-
2007
- 2007-02-16 WO PCT/IB2007/000364 patent/WO2008050185A2/fr active Application Filing
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001087836A1 (fr) * | 2000-07-06 | 2001-11-22 | Les Laboratoires Servier | Nouvelle forme cristalline $g(b) du sel de tert-butylamine du perindopril, son procede de preparation, et les compositions pharmaceutiques qui la contiennent |
WO2004113293A1 (fr) * | 2003-06-24 | 2004-12-29 | Les Laboratoires Servier | Nouvelles formes cristallines de perindopril erbumine |
WO2005037788A1 (fr) * | 2003-10-21 | 2005-04-28 | Lupin Ltd. | Nouvelle methode de preparation de perindopril erbumine cristalline |
WO2005068425A1 (fr) * | 2004-01-14 | 2005-07-28 | Lek Pharmaceuticals D.D. | Nouvelle forme cristalline de perindopril |
JP2006169169A (ja) * | 2004-12-16 | 2006-06-29 | Permachem Asia Ltd | ペリンドプリルエルブミンのi型結晶、及びその製造方法 |
Non-Patent Citations (1)
Title |
---|
BYRN S ET AL: "PHARMACEUTICAL SOLIDS: A STRATEGIC APPROACH TO REGULATORY CONSIDERATIONS", PHARMACEUTICAL RESEARCH, KLUWER ACADEMIC PUBLISHERS, NEW YORK, NY, US, vol. 12, no. 7, 1 July 1995 (1995-07-01), pages 945 - 954, XP000996386, ISSN: 0724-8741, DOI: DOI:10.1023/A:1016241927429 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112697935B (zh) * | 2020-12-10 | 2021-09-28 | 湖南泰新医药科技有限公司 | 同时测定人血浆中培哚普利和培哚普利拉浓度的方法 |
Also Published As
Publication number | Publication date |
---|---|
WO2008050185A2 (fr) | 2008-05-02 |
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