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WO2007036363A3 - Zusammensetzungen, welche buttersäureester von kohlenhydraten und kohlenhydratpolyolen enthalten - Google Patents

Zusammensetzungen, welche buttersäureester von kohlenhydraten und kohlenhydratpolyolen enthalten Download PDF

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Publication number
WO2007036363A3
WO2007036363A3 PCT/EP2006/009436 EP2006009436W WO2007036363A3 WO 2007036363 A3 WO2007036363 A3 WO 2007036363A3 EP 2006009436 W EP2006009436 W EP 2006009436W WO 2007036363 A3 WO2007036363 A3 WO 2007036363A3
Authority
WO
WIPO (PCT)
Prior art keywords
carbohydrates
acid ester
butyric acid
compositions containing
containing butyric
Prior art date
Application number
PCT/EP2006/009436
Other languages
English (en)
French (fr)
Other versions
WO2007036363A2 (de
WO2007036363A8 (de
Inventor
Begli Alireza Haji
Michael Klingeberg
Joerg Kowalczyk
Gunhild Kozianowski
Stephan Theis
Wolfgang Wach
Original Assignee
Suedzucker Ag
Begli Alireza Haji
Michael Klingeberg
Joerg Kowalczyk
Gunhild Kozianowski
Stephan Theis
Wolfgang Wach
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suedzucker Ag, Begli Alireza Haji, Michael Klingeberg, Joerg Kowalczyk, Gunhild Kozianowski, Stephan Theis, Wolfgang Wach filed Critical Suedzucker Ag
Priority to JP2008532674A priority Critical patent/JP2009509999A/ja
Priority to EP06805927A priority patent/EP1931356A2/de
Priority to US12/088,396 priority patent/US20080213341A1/en
Publication of WO2007036363A2 publication Critical patent/WO2007036363A2/de
Publication of WO2007036363A8 publication Critical patent/WO2007036363A8/de
Publication of WO2007036363A3 publication Critical patent/WO2007036363A3/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fodder In General (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

Die Erfindung betrifft Buttersäureester oder Butyratester von Kohlenhydraten und Kohlenhydratpolyolen und deren Verwendung als Butyrat-Carrier und Butyratquelle für den Magen-Darm-Trakt, insbesondere zur Vorbeugung und Behandlung von Erkrankungen des Magen-Darm-Trakts, vor allem des Dickdarms.
PCT/EP2006/009436 2005-09-28 2006-09-28 Zusammensetzungen, welche buttersäureester von kohlenhydraten und kohlenhydratpolyolen enthalten WO2007036363A2 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2008532674A JP2009509999A (ja) 2005-09-28 2006-09-28 炭水化物および炭水化物ポリオールの酪酸エステル
EP06805927A EP1931356A2 (de) 2005-09-28 2006-09-28 Zusammensetzungen, welche buttersäureester von kohlenhydraten und kohlenhydratpolyolen enthalten
US12/088,396 US20080213341A1 (en) 2005-09-28 2006-09-28 Butyric Acid Esters of Carbohydrates and Carbohydrate Polyols

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005046237A DE102005046237A1 (de) 2005-09-28 2005-09-28 Buttersäureester von Kohlenhydraten und Kohlenhydratpolyolen
DE102005046237.5 2005-09-28

Publications (3)

Publication Number Publication Date
WO2007036363A2 WO2007036363A2 (de) 2007-04-05
WO2007036363A8 WO2007036363A8 (de) 2007-06-14
WO2007036363A3 true WO2007036363A3 (de) 2007-10-11

Family

ID=37806810

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2006/009436 WO2007036363A2 (de) 2005-09-28 2006-09-28 Zusammensetzungen, welche buttersäureester von kohlenhydraten und kohlenhydratpolyolen enthalten

Country Status (6)

Country Link
US (1) US20080213341A1 (de)
EP (1) EP1931356A2 (de)
JP (1) JP2009509999A (de)
CN (1) CN101316598A (de)
DE (1) DE102005046237A1 (de)
WO (1) WO2007036363A2 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20040187A1 (it) * 2004-02-06 2004-05-06 Cosmo Spa Composizioni farmaceutiche o dietetiche a base di acidi grassi a catena corta e zuccheri complessi per le disfunzioni intestinali
US20080126195A1 (en) 2004-07-22 2008-05-29 Ritter Andrew J Methods and Compositions for Treating Lactose Intolerance
US20090297660A1 (en) * 2008-06-02 2009-12-03 Kraft Food Holdings, Inc. Cheese Products Containing Galacto-Oligosaccharides And Having Reduced Lactose Levels
US9314444B2 (en) 2009-01-12 2016-04-19 Biokier, Inc. Composition and method for treatment of NASH
US9006288B2 (en) 2009-01-12 2015-04-14 Biokier, Inc. Composition and method for treatment of diabetes
PT2376077T (pt) * 2009-01-12 2017-06-23 Biokier Inc Composição e método para tratamento de diabetes
BRPI1008280A2 (pt) 2009-02-24 2015-08-25 Ritter Pharmaceuticals Inc Formulações prebióticas e métodos mde uso
CN101647517A (zh) * 2009-06-17 2010-02-17 新奥(厦门)农牧发展有限公司 丁酸盐或丁酸甘油脂与低聚果糖的复合物及其制法和在饲料添加剂中的应用
CN101647516A (zh) * 2009-06-17 2010-02-17 新奥(厦门)农牧发展有限公司 丁酸盐或丁酸甘油脂与膳食纤维的复合物及其制法和在饲料添加剂中的应用
US9301938B2 (en) 2009-09-23 2016-04-05 Biokier, Inc. Composition and method for treatment of diabetes
WO2011107259A1 (en) * 2010-03-05 2011-09-09 Ophthalmopharma Ag Nutraceutical chocolate or compound chocolate product
WO2011137249A1 (en) 2010-04-28 2011-11-03 Ritter Pharmaceuticals, Inc. Prebiotic formulations and methods of use
CA2805445C (en) * 2010-07-29 2018-05-01 Cosmo Technologies Ltd. Pharmaceutical and/or dietary compositions based on short chain fatty acids
IT1401309B1 (it) * 2010-08-03 2013-07-18 Cosmo Technologies Ltd Pharmaceuticals and/or dietary compositions based on short chain fatty acids. composizioni farmaceutiche e/o dietetiche a base di acidi grassi a corta catena.
GB201213629D0 (en) 2012-07-31 2012-09-12 Imp Innovations Ltd Compounds and their effects on appetite control and insulin sensitivity
WO2015084158A1 (en) * 2013-12-06 2015-06-11 N.V. Nutricia A pyrimidine derivative and a fatty acid source for use in the treatment of constipation
BE1023491B1 (nl) * 2015-10-06 2017-04-06 Nutri-Ad International Nv Voedingsadditief voor gevogelte
US20170127693A1 (en) * 2015-11-09 2017-05-11 Mead Johnson Nutrition Company Nutritional compositions containing butyrate and uses thereof
US10034937B2 (en) 2015-12-04 2018-07-31 Mead Johnson Nutrition Company Synergistic nutritional compositions and uses thereof
EP3496708B1 (de) * 2016-08-10 2025-03-26 Monash University Metaboliten zur behandlung und prävention von autoimmunerkrankungen
JP2018158895A (ja) * 2017-03-22 2018-10-11 株式会社ダイセル 制御性t細胞増加剤、食品、及び医薬
EP3634430B1 (de) * 2017-06-05 2024-08-07 Flagship Pioneering Innovations V, Inc. Multibiotika und verwendungsverfahren dafür
KR102082315B1 (ko) * 2018-05-08 2020-02-27 주식회사 비피도 부티릴 프락토올리고당을 포함하는 프리바이오틱스 조성물
EP3801489A4 (de) * 2018-06-05 2022-03-30 Flagship Pioneering Innovations V, Inc. Acylierte wirkstoffe und verfahren zu deren verwendung zur behandlung von autoimmunerkrankungen
CN109504713B (zh) * 2018-12-04 2022-05-17 齐鲁工业大学 利用拜氏梭菌制备高酯键腐植酸制剂的方法及应用
US20230115476A1 (en) * 2019-12-05 2023-04-13 Societe Des Produits Nestle S.A. Dietary butyrate and its uses
JP7627109B2 (ja) 2020-12-01 2025-02-05 サンエイ糖化株式会社 コラーゲン類吸収促進剤
KR102696109B1 (ko) * 2021-10-06 2024-08-16 국립부경대학교 산학협력단 락토코커스 락티스 생육 촉진용 조성물

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5089314A (de) * 1973-12-14 1975-07-17
JPS61268192A (ja) * 1985-05-24 1986-11-27 Meito Sangyo Kk 糖類脂肪酸エステル化合物の製造法
WO1995009145A1 (en) * 1993-09-30 1995-04-06 Eastman Chemical Company NUTRITIVE GLYCEROL ESTERS OF β-ACYLOXY BUTYRATES
WO1996025380A1 (en) * 1995-02-13 1996-08-22 The Trustees Of The University Of Pennsylvania The use of tributyrin in the treatment of inflammatory bowel disease
WO2002009695A1 (en) * 2000-08-02 2002-02-07 Atossa Healthcare, Inc. Bimodal emulsions of taxanes and butyrate polyalcohol esters
WO2002039978A1 (de) * 2000-11-17 2002-05-23 Fresenius Kabi Deutschland Gmbh Enteral zu verabreichendes supplement zur parenteralen ernährung oder partiellen enteralen/oralen ernährung bei kritisch kranken, chronisch kranken und mangelernährten
US20060105962A1 (en) * 2004-11-14 2006-05-18 Robinson Robert O A Tonic to maintain intestinal flora

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3579547A (en) * 1966-12-16 1971-05-18 Scm Corp Carboxylic acid esters
US4959975A (en) * 1987-05-14 1990-10-02 Conserve, Inc. Heat pump system
FR2633929B2 (fr) * 1987-09-25 1995-05-24 Picardie Universite Derives non toxiques de l'acide n-butyrique, presentant des actions therapeutiques retardees
US4959466A (en) * 1988-01-25 1990-09-25 Arco Chemical Technology, Inc. Partially esterified polysaccharide (PEP) fat substitutes
DE4414138A1 (de) * 1994-04-22 1995-10-26 Consortium Elektrochem Ind Acylierte gamma-Cyclodextrine
FR2723096B1 (fr) * 1994-07-28 1996-10-18 Univ Picardie Esters associant les acides phenylacetique,3-phenyl-propionique, 4-phenyl-butyrique et n-butyrique au d-mannose, au xylitol et a leurs derives. applications comme medicaments
US5763488A (en) * 1995-10-30 1998-06-09 Vertex Pharmaceuticals Incorporated Methods and compositions using butyrate esters of threitol
IT1286510B1 (it) * 1996-11-29 1998-07-15 Cooperativa Centro Ricerche Po Esteri butirrici ad attivita' antiproliferativa e composizioni farmaceutiche che li contengono
DE10328180A1 (de) * 2003-06-16 2005-01-13 Südzucker AG Mannheim/Ochsenfurt Verwendung von Isomalt als Präbiotikum

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5089314A (de) * 1973-12-14 1975-07-17
JPS61268192A (ja) * 1985-05-24 1986-11-27 Meito Sangyo Kk 糖類脂肪酸エステル化合物の製造法
WO1995009145A1 (en) * 1993-09-30 1995-04-06 Eastman Chemical Company NUTRITIVE GLYCEROL ESTERS OF β-ACYLOXY BUTYRATES
WO1996025380A1 (en) * 1995-02-13 1996-08-22 The Trustees Of The University Of Pennsylvania The use of tributyrin in the treatment of inflammatory bowel disease
WO2002009695A1 (en) * 2000-08-02 2002-02-07 Atossa Healthcare, Inc. Bimodal emulsions of taxanes and butyrate polyalcohol esters
WO2002039978A1 (de) * 2000-11-17 2002-05-23 Fresenius Kabi Deutschland Gmbh Enteral zu verabreichendes supplement zur parenteralen ernährung oder partiellen enteralen/oralen ernährung bei kritisch kranken, chronisch kranken und mangelernährten
US20060105962A1 (en) * 2004-11-14 2006-05-18 Robinson Robert O A Tonic to maintain intestinal flora

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Week 197545, Derwent World Patents Index; AN 1975-74887W, XP002446087 *
DATABASE WPI Week 198702, Derwent World Patents Index; AN 1987-010766, XP002446088 *
DESMET: "Pharmacokinetic of butyric acid derivatives", EUR. J. DRUG METAB. PHARMACOKINET. 1991, no. 3, 1991, pages 348 - 351, XP008079239 *
FERGUSON MELISSA J ET AL: "Production of short-chain fatty acids following in vitro fermentation of saccharides, saccharide esters, fructo-oligosaccharides, starches, modified starches and non-starch polysaccharides", JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, vol. 80, no. 1, January 2000 (2000-01-01), pages 166 - 170, XP008079179, ISSN: 0022-5142 *
J. MULTON: "Additifs et auxiliaires de fabrications dans les indstries agro-alimentaires", 1999, APRIA, XP002434627 *
POUILLART P ET AL: "LOW LEVEL TOXICITY AND ANTITUMOR ACTIVITY OF BUTYRIC MONO- AND POLYESTER MONOSACCHARIDE DERIVATES IN MICE", JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS, WICHTIG EDITORE, MILAN, IT, vol. 4, no. 4, 1 December 1990 (1990-12-01), pages 135 - 141, XP000614299, ISSN: 0393-974X *
POUILLART PHILIPPE ET AL: "Regioselective synthesis and biological profiling of butyric and phenylalkylcarboxylic esters derivated from D-mannose and xylitol: Influence of alkyl chain length on acute toxicity", EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 7, no. 2, January 1999 (1999-01-01), pages 93 - 106, XP008079181, ISSN: 0928-0987 *
WOLFF, IVAN A.: "Acetates, propionates, and butyrates of simple saccharides", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY , 67, 1623-4 CODEN: JACSAT; ISSN: 0002-7863, 1945, XP008082241 *

Also Published As

Publication number Publication date
US20080213341A1 (en) 2008-09-04
EP1931356A2 (de) 2008-06-18
WO2007036363A2 (de) 2007-04-05
JP2009509999A (ja) 2009-03-12
WO2007036363A8 (de) 2007-06-14
DE102005046237A1 (de) 2007-04-05
CN101316598A (zh) 2008-12-03

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