WO2007036363A3 - Zusammensetzungen, welche buttersäureester von kohlenhydraten und kohlenhydratpolyolen enthalten - Google Patents
Zusammensetzungen, welche buttersäureester von kohlenhydraten und kohlenhydratpolyolen enthalten Download PDFInfo
- Publication number
- WO2007036363A3 WO2007036363A3 PCT/EP2006/009436 EP2006009436W WO2007036363A3 WO 2007036363 A3 WO2007036363 A3 WO 2007036363A3 EP 2006009436 W EP2006009436 W EP 2006009436W WO 2007036363 A3 WO2007036363 A3 WO 2007036363A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- carbohydrates
- acid ester
- butyric acid
- compositions containing
- containing butyric
- Prior art date
Links
- 235000014633 carbohydrates Nutrition 0.000 title abstract 4
- 150000001656 butanoic acid esters Chemical class 0.000 title abstract 2
- -1 carbohydrate polyols Chemical class 0.000 title abstract 2
- 150000001720 carbohydrates Chemical class 0.000 title abstract 2
- 229920005862 polyol Polymers 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract 2
- 210000001072 colon Anatomy 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- OBNCKNCVKJNDBV-UHFFFAOYSA-N ethyl butyrate Chemical compound CCCC(=O)OCC OBNCKNCVKJNDBV-UHFFFAOYSA-N 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Fodder In General (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
Die Erfindung betrifft Buttersäureester oder Butyratester von Kohlenhydraten und Kohlenhydratpolyolen und deren Verwendung als Butyrat-Carrier und Butyratquelle für den Magen-Darm-Trakt, insbesondere zur Vorbeugung und Behandlung von Erkrankungen des Magen-Darm-Trakts, vor allem des Dickdarms.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2008532674A JP2009509999A (ja) | 2005-09-28 | 2006-09-28 | 炭水化物および炭水化物ポリオールの酪酸エステル |
EP06805927A EP1931356A2 (de) | 2005-09-28 | 2006-09-28 | Zusammensetzungen, welche buttersäureester von kohlenhydraten und kohlenhydratpolyolen enthalten |
US12/088,396 US20080213341A1 (en) | 2005-09-28 | 2006-09-28 | Butyric Acid Esters of Carbohydrates and Carbohydrate Polyols |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102005046237A DE102005046237A1 (de) | 2005-09-28 | 2005-09-28 | Buttersäureester von Kohlenhydraten und Kohlenhydratpolyolen |
DE102005046237.5 | 2005-09-28 |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2007036363A2 WO2007036363A2 (de) | 2007-04-05 |
WO2007036363A8 WO2007036363A8 (de) | 2007-06-14 |
WO2007036363A3 true WO2007036363A3 (de) | 2007-10-11 |
Family
ID=37806810
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2006/009436 WO2007036363A2 (de) | 2005-09-28 | 2006-09-28 | Zusammensetzungen, welche buttersäureester von kohlenhydraten und kohlenhydratpolyolen enthalten |
Country Status (6)
Country | Link |
---|---|
US (1) | US20080213341A1 (de) |
EP (1) | EP1931356A2 (de) |
JP (1) | JP2009509999A (de) |
CN (1) | CN101316598A (de) |
DE (1) | DE102005046237A1 (de) |
WO (1) | WO2007036363A2 (de) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ITMI20040187A1 (it) * | 2004-02-06 | 2004-05-06 | Cosmo Spa | Composizioni farmaceutiche o dietetiche a base di acidi grassi a catena corta e zuccheri complessi per le disfunzioni intestinali |
US20080126195A1 (en) | 2004-07-22 | 2008-05-29 | Ritter Andrew J | Methods and Compositions for Treating Lactose Intolerance |
US20090297660A1 (en) * | 2008-06-02 | 2009-12-03 | Kraft Food Holdings, Inc. | Cheese Products Containing Galacto-Oligosaccharides And Having Reduced Lactose Levels |
US9314444B2 (en) | 2009-01-12 | 2016-04-19 | Biokier, Inc. | Composition and method for treatment of NASH |
US9006288B2 (en) | 2009-01-12 | 2015-04-14 | Biokier, Inc. | Composition and method for treatment of diabetes |
PT2376077T (pt) * | 2009-01-12 | 2017-06-23 | Biokier Inc | Composição e método para tratamento de diabetes |
BRPI1008280A2 (pt) | 2009-02-24 | 2015-08-25 | Ritter Pharmaceuticals Inc | Formulações prebióticas e métodos mde uso |
CN101647517A (zh) * | 2009-06-17 | 2010-02-17 | 新奥(厦门)农牧发展有限公司 | 丁酸盐或丁酸甘油脂与低聚果糖的复合物及其制法和在饲料添加剂中的应用 |
CN101647516A (zh) * | 2009-06-17 | 2010-02-17 | 新奥(厦门)农牧发展有限公司 | 丁酸盐或丁酸甘油脂与膳食纤维的复合物及其制法和在饲料添加剂中的应用 |
US9301938B2 (en) | 2009-09-23 | 2016-04-05 | Biokier, Inc. | Composition and method for treatment of diabetes |
WO2011107259A1 (en) * | 2010-03-05 | 2011-09-09 | Ophthalmopharma Ag | Nutraceutical chocolate or compound chocolate product |
WO2011137249A1 (en) | 2010-04-28 | 2011-11-03 | Ritter Pharmaceuticals, Inc. | Prebiotic formulations and methods of use |
CA2805445C (en) * | 2010-07-29 | 2018-05-01 | Cosmo Technologies Ltd. | Pharmaceutical and/or dietary compositions based on short chain fatty acids |
IT1401309B1 (it) * | 2010-08-03 | 2013-07-18 | Cosmo Technologies Ltd | Pharmaceuticals and/or dietary compositions based on short chain fatty acids. composizioni farmaceutiche e/o dietetiche a base di acidi grassi a corta catena. |
GB201213629D0 (en) | 2012-07-31 | 2012-09-12 | Imp Innovations Ltd | Compounds and their effects on appetite control and insulin sensitivity |
WO2015084158A1 (en) * | 2013-12-06 | 2015-06-11 | N.V. Nutricia | A pyrimidine derivative and a fatty acid source for use in the treatment of constipation |
BE1023491B1 (nl) * | 2015-10-06 | 2017-04-06 | Nutri-Ad International Nv | Voedingsadditief voor gevogelte |
US20170127693A1 (en) * | 2015-11-09 | 2017-05-11 | Mead Johnson Nutrition Company | Nutritional compositions containing butyrate and uses thereof |
US10034937B2 (en) | 2015-12-04 | 2018-07-31 | Mead Johnson Nutrition Company | Synergistic nutritional compositions and uses thereof |
EP3496708B1 (de) * | 2016-08-10 | 2025-03-26 | Monash University | Metaboliten zur behandlung und prävention von autoimmunerkrankungen |
JP2018158895A (ja) * | 2017-03-22 | 2018-10-11 | 株式会社ダイセル | 制御性t細胞増加剤、食品、及び医薬 |
EP3634430B1 (de) * | 2017-06-05 | 2024-08-07 | Flagship Pioneering Innovations V, Inc. | Multibiotika und verwendungsverfahren dafür |
KR102082315B1 (ko) * | 2018-05-08 | 2020-02-27 | 주식회사 비피도 | 부티릴 프락토올리고당을 포함하는 프리바이오틱스 조성물 |
EP3801489A4 (de) * | 2018-06-05 | 2022-03-30 | Flagship Pioneering Innovations V, Inc. | Acylierte wirkstoffe und verfahren zu deren verwendung zur behandlung von autoimmunerkrankungen |
CN109504713B (zh) * | 2018-12-04 | 2022-05-17 | 齐鲁工业大学 | 利用拜氏梭菌制备高酯键腐植酸制剂的方法及应用 |
US20230115476A1 (en) * | 2019-12-05 | 2023-04-13 | Societe Des Produits Nestle S.A. | Dietary butyrate and its uses |
JP7627109B2 (ja) | 2020-12-01 | 2025-02-05 | サンエイ糖化株式会社 | コラーゲン類吸収促進剤 |
KR102696109B1 (ko) * | 2021-10-06 | 2024-08-16 | 국립부경대학교 산학협력단 | 락토코커스 락티스 생육 촉진용 조성물 |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5089314A (de) * | 1973-12-14 | 1975-07-17 | ||
JPS61268192A (ja) * | 1985-05-24 | 1986-11-27 | Meito Sangyo Kk | 糖類脂肪酸エステル化合物の製造法 |
WO1995009145A1 (en) * | 1993-09-30 | 1995-04-06 | Eastman Chemical Company | NUTRITIVE GLYCEROL ESTERS OF β-ACYLOXY BUTYRATES |
WO1996025380A1 (en) * | 1995-02-13 | 1996-08-22 | The Trustees Of The University Of Pennsylvania | The use of tributyrin in the treatment of inflammatory bowel disease |
WO2002009695A1 (en) * | 2000-08-02 | 2002-02-07 | Atossa Healthcare, Inc. | Bimodal emulsions of taxanes and butyrate polyalcohol esters |
WO2002039978A1 (de) * | 2000-11-17 | 2002-05-23 | Fresenius Kabi Deutschland Gmbh | Enteral zu verabreichendes supplement zur parenteralen ernährung oder partiellen enteralen/oralen ernährung bei kritisch kranken, chronisch kranken und mangelernährten |
US20060105962A1 (en) * | 2004-11-14 | 2006-05-18 | Robinson Robert O A | Tonic to maintain intestinal flora |
Family Cites Families (9)
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US3579547A (en) * | 1966-12-16 | 1971-05-18 | Scm Corp | Carboxylic acid esters |
US4959975A (en) * | 1987-05-14 | 1990-10-02 | Conserve, Inc. | Heat pump system |
FR2633929B2 (fr) * | 1987-09-25 | 1995-05-24 | Picardie Universite | Derives non toxiques de l'acide n-butyrique, presentant des actions therapeutiques retardees |
US4959466A (en) * | 1988-01-25 | 1990-09-25 | Arco Chemical Technology, Inc. | Partially esterified polysaccharide (PEP) fat substitutes |
DE4414138A1 (de) * | 1994-04-22 | 1995-10-26 | Consortium Elektrochem Ind | Acylierte gamma-Cyclodextrine |
FR2723096B1 (fr) * | 1994-07-28 | 1996-10-18 | Univ Picardie | Esters associant les acides phenylacetique,3-phenyl-propionique, 4-phenyl-butyrique et n-butyrique au d-mannose, au xylitol et a leurs derives. applications comme medicaments |
US5763488A (en) * | 1995-10-30 | 1998-06-09 | Vertex Pharmaceuticals Incorporated | Methods and compositions using butyrate esters of threitol |
IT1286510B1 (it) * | 1996-11-29 | 1998-07-15 | Cooperativa Centro Ricerche Po | Esteri butirrici ad attivita' antiproliferativa e composizioni farmaceutiche che li contengono |
DE10328180A1 (de) * | 2003-06-16 | 2005-01-13 | Südzucker AG Mannheim/Ochsenfurt | Verwendung von Isomalt als Präbiotikum |
-
2005
- 2005-09-28 DE DE102005046237A patent/DE102005046237A1/de not_active Withdrawn
-
2006
- 2006-09-28 WO PCT/EP2006/009436 patent/WO2007036363A2/de active Application Filing
- 2006-09-28 US US12/088,396 patent/US20080213341A1/en not_active Abandoned
- 2006-09-28 EP EP06805927A patent/EP1931356A2/de not_active Withdrawn
- 2006-09-28 JP JP2008532674A patent/JP2009509999A/ja not_active Withdrawn
- 2006-09-28 CN CNA200680044065XA patent/CN101316598A/zh active Pending
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5089314A (de) * | 1973-12-14 | 1975-07-17 | ||
JPS61268192A (ja) * | 1985-05-24 | 1986-11-27 | Meito Sangyo Kk | 糖類脂肪酸エステル化合物の製造法 |
WO1995009145A1 (en) * | 1993-09-30 | 1995-04-06 | Eastman Chemical Company | NUTRITIVE GLYCEROL ESTERS OF β-ACYLOXY BUTYRATES |
WO1996025380A1 (en) * | 1995-02-13 | 1996-08-22 | The Trustees Of The University Of Pennsylvania | The use of tributyrin in the treatment of inflammatory bowel disease |
WO2002009695A1 (en) * | 2000-08-02 | 2002-02-07 | Atossa Healthcare, Inc. | Bimodal emulsions of taxanes and butyrate polyalcohol esters |
WO2002039978A1 (de) * | 2000-11-17 | 2002-05-23 | Fresenius Kabi Deutschland Gmbh | Enteral zu verabreichendes supplement zur parenteralen ernährung oder partiellen enteralen/oralen ernährung bei kritisch kranken, chronisch kranken und mangelernährten |
US20060105962A1 (en) * | 2004-11-14 | 2006-05-18 | Robinson Robert O A | Tonic to maintain intestinal flora |
Non-Patent Citations (8)
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DATABASE WPI Week 197545, Derwent World Patents Index; AN 1975-74887W, XP002446087 * |
DATABASE WPI Week 198702, Derwent World Patents Index; AN 1987-010766, XP002446088 * |
DESMET: "Pharmacokinetic of butyric acid derivatives", EUR. J. DRUG METAB. PHARMACOKINET. 1991, no. 3, 1991, pages 348 - 351, XP008079239 * |
FERGUSON MELISSA J ET AL: "Production of short-chain fatty acids following in vitro fermentation of saccharides, saccharide esters, fructo-oligosaccharides, starches, modified starches and non-starch polysaccharides", JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, vol. 80, no. 1, January 2000 (2000-01-01), pages 166 - 170, XP008079179, ISSN: 0022-5142 * |
J. MULTON: "Additifs et auxiliaires de fabrications dans les indstries agro-alimentaires", 1999, APRIA, XP002434627 * |
POUILLART P ET AL: "LOW LEVEL TOXICITY AND ANTITUMOR ACTIVITY OF BUTYRIC MONO- AND POLYESTER MONOSACCHARIDE DERIVATES IN MICE", JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS, WICHTIG EDITORE, MILAN, IT, vol. 4, no. 4, 1 December 1990 (1990-12-01), pages 135 - 141, XP000614299, ISSN: 0393-974X * |
POUILLART PHILIPPE ET AL: "Regioselective synthesis and biological profiling of butyric and phenylalkylcarboxylic esters derivated from D-mannose and xylitol: Influence of alkyl chain length on acute toxicity", EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 7, no. 2, January 1999 (1999-01-01), pages 93 - 106, XP008079181, ISSN: 0928-0987 * |
WOLFF, IVAN A.: "Acetates, propionates, and butyrates of simple saccharides", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY , 67, 1623-4 CODEN: JACSAT; ISSN: 0002-7863, 1945, XP008082241 * |
Also Published As
Publication number | Publication date |
---|---|
US20080213341A1 (en) | 2008-09-04 |
EP1931356A2 (de) | 2008-06-18 |
WO2007036363A2 (de) | 2007-04-05 |
JP2009509999A (ja) | 2009-03-12 |
WO2007036363A8 (de) | 2007-06-14 |
DE102005046237A1 (de) | 2007-04-05 |
CN101316598A (zh) | 2008-12-03 |
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