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WO2007028133A3 - Traitement et procede de prevention de la demence vasculaire - Google Patents

Traitement et procede de prevention de la demence vasculaire Download PDF

Info

Publication number
WO2007028133A3
WO2007028133A3 PCT/US2006/034432 US2006034432W WO2007028133A3 WO 2007028133 A3 WO2007028133 A3 WO 2007028133A3 US 2006034432 W US2006034432 W US 2006034432W WO 2007028133 A3 WO2007028133 A3 WO 2007028133A3
Authority
WO
WIPO (PCT)
Prior art keywords
vascular dementia
prevention
treatment
mammal
treating
Prior art date
Application number
PCT/US2006/034432
Other languages
English (en)
Other versions
WO2007028133A2 (fr
Inventor
John M Hallenbeck
Hideaki Wakita
Original Assignee
Us Gov Health & Human Serv
John M Hallenbeck
Hideaki Wakita
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Gov Health & Human Serv, John M Hallenbeck, Hideaki Wakita filed Critical Us Gov Health & Human Serv
Publication of WO2007028133A2 publication Critical patent/WO2007028133A2/fr
Publication of WO2007028133A3 publication Critical patent/WO2007028133A3/fr
Priority to US12/072,914 priority Critical patent/US7897575B2/en
Priority to US12/859,048 priority patent/US8940700B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention porte sur des compositions et sur des méthodes de traitement ou de prévention de la démence vasculaire chez un mammifère, ces méthodes consistant à administrer par les muqueuses une quantité suffisante du polypeptide E-sélectine pour induire une tolérance immune de voisinage chez le mammifère. L'invention porte également sur des compositions utiles dans le traitement ou la prévention de la démence vasculaire.
PCT/US2006/034432 2000-05-24 2006-08-30 Traitement et procede de prevention de la demence vasculaire WO2007028133A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US12/072,914 US7897575B2 (en) 2000-05-24 2008-02-28 Treatment and prevention of vascular dementia
US12/859,048 US8940700B2 (en) 2000-05-24 2010-08-18 E-selectin compositions and use thereof for inducing E-selectin tolerance

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71235905P 2005-08-30 2005-08-30
US60/712,359 2005-08-30

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/021682 Continuation-In-Part WO2008045488A2 (fr) 2000-05-24 2007-10-09 Traitement de l'inflammation, de la démyélinisation et de la perte neuronale/axonale

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US12/072,914 Continuation-In-Part US7897575B2 (en) 2000-05-24 2008-02-28 Treatment and prevention of vascular dementia

Publications (2)

Publication Number Publication Date
WO2007028133A2 WO2007028133A2 (fr) 2007-03-08
WO2007028133A3 true WO2007028133A3 (fr) 2007-04-26

Family

ID=37698322

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/034432 WO2007028133A2 (fr) 2000-05-24 2006-08-30 Traitement et procede de prevention de la demence vasculaire

Country Status (1)

Country Link
WO (1) WO2007028133A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7897575B2 (en) 2000-05-24 2011-03-01 The United States Of America As Represented By The Department Of Health And Human Services Treatment and prevention of vascular dementia
US20070244043A1 (en) * 2005-03-10 2007-10-18 Novavax, Inc. Recombinant E-selectin made in insect cells
AU2007308158A1 (en) * 2006-10-09 2008-04-17 Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, National Institutes Of Health Treatment of inflammation, demyelination and neuronal/axonal loss
ES2540933T3 (es) 2007-05-11 2015-07-14 Thomas Jefferson University Métodos de tratamiento y prevención de enfermedades y trastornos neurodegenerativos
US10391068B2 (en) 2012-08-06 2019-08-27 Trustees Of Boston University Prion protein ligands as therapeutic agents for neurodegenerative disorders

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001089557A2 (fr) * 2000-05-24 2001-11-29 The United States Of America, As Represented By Secretary Of The Department Of Health & Human Services Methodes de prevention des accidents vasculaires cerebraux moyennant l'induction d'une tolerance a e-selectin

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001089557A2 (fr) * 2000-05-24 2001-11-29 The United States Of America, As Represented By Secretary Of The Department Of Health & Human Services Methodes de prevention des accidents vasculaires cerebraux moyennant l'induction d'une tolerance a e-selectin

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
WANG X ET AL: "DEMONSTRATION OF INCREASED ENDOTHELIAL-LEUKOCYTE ADHESION MOLECULE-1 MRNA EXPRESSION IN RAT ISCHEMIC CORTEX", STROKE, AMERICAN HEART ASSOCIATION, DALLAS TX, US, vol. 26, no. 9, 1995, pages 1665 - 1669, XP001064744, ISSN: 0039-2499 *
ZOPPO DEL G ET AL: "INFLAMMATION AND STROKE: PUTATIVE ROLE FOR CYTOKINES, ADHESION MOLECULES AND iNOS IN BRAIN RESPONSE TO ISCHEMIA", BRAIN PATHOLOGY, ZUERICH, CH, vol. 10, no. 1, January 2000 (2000-01-01), pages 95 - 112, XP001008248, ISSN: 1015-6305 *

Also Published As

Publication number Publication date
WO2007028133A2 (fr) 2007-03-08

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