WO2007016795A1 - Dispositif pour une prothese artificielle d'articulation chez l'homme et l'animal - Google Patents
Dispositif pour une prothese artificielle d'articulation chez l'homme et l'animal Download PDFInfo
- Publication number
- WO2007016795A1 WO2007016795A1 PCT/CH2005/000463 CH2005000463W WO2007016795A1 WO 2007016795 A1 WO2007016795 A1 WO 2007016795A1 CH 2005000463 W CH2005000463 W CH 2005000463W WO 2007016795 A1 WO2007016795 A1 WO 2007016795A1
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- WO
- WIPO (PCT)
- Prior art keywords
- particles
- sliding
- polymer matrix
- nanometers
- embedded
- Prior art date
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Classifications
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/40—Joints for shoulders
- A61F2/4014—Humeral heads or necks; Connections of endoprosthetic heads or necks to endoprosthetic humeral shafts
- A61F2002/4018—Heads or epiphyseal parts of humerus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/46—Special tools for implanting artificial joints
- A61F2002/4631—Special tools for implanting artificial joints the prosthesis being specially adapted for being cemented
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00011—Metals or alloys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00179—Ceramics or ceramic-like structures
Definitions
- the present invention relates to a device according to the preamble of claim 1.
- it relates to applications in hip, knee and shoulder arthroplasty.
- polyethylene / metal or polyethylene / ceramics that are most commonly used as sliding partners in joint endoprosthetics are currently being used.
- polyethylene (PE) as ultrahigh-molecular-weight PE (UHMWPE) forms the socket material, while the ball consists of metal or ceramic, mostly Al 2 O 3 or ZrO 2 ceramics.
- metal-metal and ceramic-ceramic pairings have already been clinically proven, they have better wear and sliding properties than UHMWPE / metal or UHMWPE / ceramic pairings.
- disadvantageous from a material point of view is the damping behavior, the possibility of destruction of the surface of metal-metal pairings by third particles and, in the case of ceramic-ceramic pairings, additionally the material brittleness, which can lead to the catastrophic breakage of the implant components.
- the manufacturing costs for these so-called hard-hard pairings are higher than for pairings with UHMWPE.
- the excellent wear characteristics of metal-to-metal sliding pairings are based on the fact that the cobalt alloys used consist of a metallic matrix and embedded fine hard carbides. When articulating touch virtually only the hard carbides and the softer matrix is thereby spared.
- This surface structure also has a positive effect on the lubrication of the system in that the matrix, which is slightly recessed relative to the sliding surface carbides, promotes the formation of a lubricating film.
- the inorganic reinforcement phase has a particle size distribution of the order of micrometers.
- the disadvantage of these concepts is the risk that individual particles are torn out of the sliding surface as the state of wear progresses, scratch the surface and then lead to a catastrophic wear progress with destruction of the sliding surface.
- the device according to the invention is designed as a joint endoprosthesis, typically with a concave and a convex sliding surface.
- the advantage of the invention is that the amplification phase has a great effect of reducing the rate of wear. Nevertheless, the embedded particles - because of their small size in the nanometer scale - even if they are torn out of the sliding surface, they do not damage.
- the advantage according to the invention exists that certain properties of the polymeric matrix-for example, the fracture toughness-are less impaired by the use of nanoparticles as a reinforcing phase in comparison with particles in the micrometer scale.
- the tribological properties of the inventive device are comparable to those of metal / metal pairings based on cobalt alloys with embedded carbides.
- the tribological properties of the inventive device are comparable to those of metal / metal pairings based on cobalt alloys with embedded carbides.
- Suitable polymer matrix are the proven in vivo long-term stable polymers.
- Ultra-high molecular weight polyethylene UHMWPE
- PTFE polytetrafluoroethylene
- PAEK polyaryletherketones
- these polymers have a high stability in the body milieu, on the other hand, it is also necessary to exclude questionable degradation products in the case of a slight degradation of these materials in the body, which can not be completely ruled out. They also have very good mechanical properties and have proven themselves in various applications as implant materials.
- Reinforcing phases are inert inert inorganic-non-metallic (ceramic) materials.
- Ceramic materials based on oxides, nitrides or carbides, in particular of the following types: Al 2 O 3, TiO 2, ZrO 2, SiO 2 , Al 2 SiO, SiC, Si 3 N 4 , BaSO 4 or a mixture thereof, have proven useful for this purpose.
- these inorganic-non-metallic materials have a high hardness and wear resistance, on the other hand they do not behave completely Excluded case of release of these materials in the body inert. These materials lead to a further improvement of the tribological properties.
- the embedded in the polymer matrix parts of inorganic non-metallic material act primarily as Abrasionsciosventoren and preferably have a spherical shape, a ball-like or a roundish shape.
- the lack of sharp edges or tips lessens the surface of the other metallic or ceramic sliding partner.
- the two sliding surfaces may consist of a metallic or ceramic, but also of an unreinforced polymeric material. Especially in prostheses with high mechanical stress, e.g. In hip and knee joint prostheses, metallic or ceramic materials are particularly well suited.
- the inorganic-non-metallic material is advantageously at least 90 wt .-% of a plurality of particles having an average diameter of less than 200 nanometers.
- the particles advantageously have a spherical shape, a spherical or a roundish shape.
- the size distribution of the individual particles incorporated into the polymer matrix is preferably such that the mean value of the largest diameters of the particles is less than 100 nanometers, preferably less than 60 nanometers. This results in a further improvement of the tribological properties.
- the size distribution of the individual particles incorporated into the polymer matrix is such that the mean value of the smallest diameters of the particles is above 5 nanometers, preferably above 10 nanometers.
- the inorganic-non-metallic material is expediently selected from the group of bioinert and / or biocompatible ceramics of high hardness, preferably the oxides, nitrides or carbides, in particular the following types: Al 2 O 3 , TiO 2 , ZrO 2 , SiO 2 , Al 2 SiO 5 , SiC, Si 3 N 4 , BaSO 4 or a mixture of these compounds.
- the particles are homogeneously distributed throughout the polymer matrix.
- the tribological properties can be further improved.
- the particles are incorporated only to a depth of 2 mm in the polymer matrix.
- the particles incorporated in the polymer matrix expediently make up a proportion of between 1 and 25 percent by weight, preferably between 5 and 15 percent by weight, of the composite material. Higher levels of embedded particles can lead to unwanted embrittlement.
- the particles incorporated in the polymer matrix expediently have a Mohs hardness of greater than 5, preferably greater than 7.
- At least one of the two sliding surfaces is formed on the associated sliding component as a surface layer, and preferably has a maximum layer thickness of 2 mm.
- the composite consisted of a polyetheretherketone matrix (PEEK) with 15% by weight finely dispersed nanoparticles of titanium oxide (TiO 2 ) with a size distribution between 40 and 60 nm.
- PEEK polyetheretherketone matrix
- TiO 2 titanium oxide
- This composite material was mixed by known processes of polymer processing, eg by melting the polymer produced with the nanoparticles, extrusion, granulation and processing of the granules by injection molding and processed into a final product, eg an artificial acetabulum.
- the composite consisted of a polyaryletherketone matrix (PAEK) with 10% by weight finely dispersed embedded nanoparticles of aluminum oxide (Al 2 O 3 ) with a size distribution between 60 and 90 nm.
- PEEK polyaryletherketone matrix
- Al 2 O 3 aluminum oxide
- This composite material was prepared by known processes of polymer processing, eg by melting of the polymer , Mixing with the nanoparticles, extrusion, granulation and processing of the granules by injection molding and processed into a component for a knee joint prosthesis.
- the composite consisted of a polytetrafluoroethylene matrix (PTFE) with 5% by weight finely dispersed embedded nanoparticles of zirconium oxide (ZrO ⁇ ) with a size distribution between 80 and 100 nm.
- PTFE polytetrafluoroethylene matrix
- ZrO ⁇ zirconium oxide
- This composite material was mixed by known processes of polymer processing, eg by melting the polymer manufactured using the nanoparticles, extrusion, granulation and processing of the granules by injection molding and processed into a component for a shoulder joint prosthesis.
- FIG. 1 shows a schematic cross section through a hip joint endoprosthesis.
- FIG. 2 shows a schematic cross section through a shoulder joint endoprosthesis
- FIG. 3 shows a schematic cross section through a knee joint endoprosthesis
- Fig. 4 is a schematic cross-section through another embodiment of a
- FIG. 5 shows a schematic cross section through a further embodiment of a
- FIG. 1 shows the schematic structure of a joint endoprosthesis 1 using the example of a hip prosthesis.
- the first, anchored in the acetabulum sliding component 2 consists of a material 7 which has been prepared according to one of the above examples 1 or 2. Its concave (hollow spherical) sliding surface 4 is polished smooth.
- the corresponding to the acetabular component second sliding component 3 is formed as a femoral component, made of metal or ceramic and has a polished convex (spherical) sliding surface 5 of the ball head 6.
- a shoulder joint endoprosthesis with a joint shell and a ball head having humeral component is shown.
- the first sliding component 2 is designed as a joint shell with a concave (spherical) first sliding surface 4 and anchored in the scapula 13 according to one of the known surgical techniques, for example by means of bone screws 10 and bone cement.
- the second sliding component 3 comprises a ball head 6, which has a second, with the first sliding surface 4 articulating sliding surface 5, and a shaft 11 which is inserted into the drilled medullary space in the humerus 12 and fixed there by means of a bone cement in the bone.
- the trained as a joint shell first sliding component 2 and the ball head 6 here consist both of a material 7 which was prepared according to the above example.
- the first, concave and the second, convex sliding surface 4, 5 are polished smooth.
- the shaft 11 of the humeral component is preferably made of a metal and on the ball head 6 attached axially and stable to rotation.
- FIG. 3 Shown in FIG. 3 is a knee joint endoprosthesis with a femoral component, which has convexly curved sliding surfaces 5, and a tibial component, which has concave sliding surfaces 4.
- the first sliding component 2 is designed as a tibial component and comprises a plate 17 lying on the resected tibial plateau, on whose surface adjacent to the condyles two concave, first sliding surfaces 4 are arranged as depressions.
- the second sliding component 3 is designed as a femoral component and comprises two convex second sliding surfaces 5 corresponding to the condyles, which articulate with the first sliding surfaces 4 on the femoral component.
- the femoral component is anchored according to one of the known surgical techniques, for example by means of two pins 16 cemented in the distal femoral head, while the tibial component is fastened to the proximal tibia by means of bone screws 10.
- the formed as a plate first sliding component 2 consists of a material 7 which was prepared according to the above example.
- the first, concave sliding surfaces 4 are polished smooth.
- the second sliding component 3 is made of metal or ceramic, and the convex second sliding surfaces 5 are also polished.
- FIG. 4 shows a first sliding component 2 designed as an acetabular component, which consists entirely of a material 7 which has been produced according to one of the examples given above.
- FIG. 5 shows a first sliding component 2 designed as an acetabular component, which is assembled from an outer spherical shell 8 and an inner shell 9, which has the concave spherical first sliding surface 4.
- the inner shell 9 is made of a material 7, which was prepared according to one of the above examples, while the outer shell 8 is made for example of ultra-high molecular weight polyethylene (UHMWPE).
- UHMWPE ultra-high molecular weight polyethylene
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Medicinal Chemistry (AREA)
- Materials Engineering (AREA)
- Composite Materials (AREA)
- Inorganic Chemistry (AREA)
- Manufacturing & Machinery (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
Abstract
Dispositif (1) pour une prothèse artificielle d'articulation chez l'homme et l'animal, qui comporte une première composante de glissement (2) possédant une première surface de glissement (4) et une seconde composante de glissement (3) possédant une seconde surface de glissement (5) s'articulant avec la première surface de glissement (4), si bien que les première et seconde composantes de glissement (2, 3) forment une liaison articulée. Au moins une des deux surfaces de glissement (4, 5) est constituée d'une matière composite (7) contenant au moins une matière inorganique non métallique incorporée dans une matrice polymère, ladite matière inorganique non métallique comportant une pluralité de particules ayant un diamètre moyen inférieur à 200 nanomètres.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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PCT/CH2005/000463 WO2007016795A1 (fr) | 2005-08-09 | 2005-08-09 | Dispositif pour une prothese artificielle d'articulation chez l'homme et l'animal |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/CH2005/000463 WO2007016795A1 (fr) | 2005-08-09 | 2005-08-09 | Dispositif pour une prothese artificielle d'articulation chez l'homme et l'animal |
Publications (1)
Publication Number | Publication Date |
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WO2007016795A1 true WO2007016795A1 (fr) | 2007-02-15 |
Family
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PCT/CH2005/000463 WO2007016795A1 (fr) | 2005-08-09 | 2005-08-09 | Dispositif pour une prothese artificielle d'articulation chez l'homme et l'animal |
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WO (1) | WO2007016795A1 (fr) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2469991A (en) * | 2009-04-21 | 2010-11-10 | Invibio Ltd | Polymeric materials with improved impact strength |
EP2258319A1 (fr) * | 2009-06-04 | 2010-12-08 | Howmedica Osteonics Corp. | Supports orthopédiques PAEC sur polymère |
WO2014068285A1 (fr) * | 2012-11-01 | 2014-05-08 | Invibio Limited | Roulement à billes polymère sur polymère orthopédique |
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EP0692227A1 (fr) * | 1994-07-11 | 1996-01-17 | SULZER Medizinaltechnik AG | Implant en nappe |
US6290726B1 (en) * | 2000-01-30 | 2001-09-18 | Diamicron, Inc. | Prosthetic hip joint having sintered polycrystalline diamond compact articulation surfaces |
DE10055465A1 (de) * | 2000-11-09 | 2002-05-23 | Blz Gmbh | Knochenersatzwerkstoff und Verfahren zur Herstellung eines Knochenersatz-Implantats |
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DE3917035A1 (de) * | 1988-05-30 | 1990-02-08 | Inst Leichtbau Und Oekonomisch | Gleitpartner fuer gelenkendoprothesen und verfahren zur herstellung der gleitpartner fuer gelenkendoprothesen |
WO1994007810A1 (fr) * | 1992-09-29 | 1994-04-14 | Commonwealth Scientific And Industrial Research Organisation | Surfaces de carbone resistantes a l'usure |
EP0607017A1 (fr) * | 1993-01-11 | 1994-07-20 | TDK Corporation | Prothése implantable en composite bioactif et son méthode de fabrication |
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US6290726B1 (en) * | 2000-01-30 | 2001-09-18 | Diamicron, Inc. | Prosthetic hip joint having sintered polycrystalline diamond compact articulation surfaces |
DE10055465A1 (de) * | 2000-11-09 | 2002-05-23 | Blz Gmbh | Knochenersatzwerkstoff und Verfahren zur Herstellung eines Knochenersatz-Implantats |
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2469991A (en) * | 2009-04-21 | 2010-11-10 | Invibio Ltd | Polymeric materials with improved impact strength |
GB2469991B (en) * | 2009-04-21 | 2013-08-07 | Invibio Ltd | Polymeric materials |
EP2258319A1 (fr) * | 2009-06-04 | 2010-12-08 | Howmedica Osteonics Corp. | Supports orthopédiques PAEC sur polymère |
EP3020374A1 (fr) * | 2009-06-04 | 2016-05-18 | Howmedica Osteonics Corp. | Supports orthopediques paec sur polymere |
US9907660B2 (en) | 2009-06-04 | 2018-03-06 | Howmedica Osteonics Corp. | Orthopedic paek-on-polymer bearings |
EP3431044A1 (fr) * | 2009-06-04 | 2019-01-23 | Howmedica Osteonics Corp. | Supports orthopédiques paec sur polymère |
US12076246B2 (en) | 2009-06-04 | 2024-09-03 | Howmedica Osteonics Corp. | Orthopedic PAEK-on-polymer bearings |
WO2014068285A1 (fr) * | 2012-11-01 | 2014-05-08 | Invibio Limited | Roulement à billes polymère sur polymère orthopédique |
GB2510014A (en) * | 2012-11-01 | 2014-07-23 | Invibio Ltd | Orthopaedic polymer-on-polymer bearing |
GB2510014B (en) * | 2012-11-01 | 2018-02-14 | Invibio Ltd | Orthopaedic polymer-on-polymer bearings |
US11103352B2 (en) | 2012-11-01 | 2021-08-31 | Invibio Limited | Orthopaedic polymer-on-polymer bearings |
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