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WO2007011827A3 - Agents cytostatiques g1 renforçant l'activite antivirale des medicaments et anticorps diriges contre l'enveloppe virale - Google Patents

Agents cytostatiques g1 renforçant l'activite antivirale des medicaments et anticorps diriges contre l'enveloppe virale Download PDF

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Publication number
WO2007011827A3
WO2007011827A3 PCT/US2006/027584 US2006027584W WO2007011827A3 WO 2007011827 A3 WO2007011827 A3 WO 2007011827A3 US 2006027584 W US2006027584 W US 2006027584W WO 2007011827 A3 WO2007011827 A3 WO 2007011827A3
Authority
WO
WIPO (PCT)
Prior art keywords
viral
antibodies
cytostatic agents
antiviral activity
targeting drugs
Prior art date
Application number
PCT/US2006/027584
Other languages
English (en)
Other versions
WO2007011827A2 (fr
Inventor
Alonso Heredia
George Lewis
Anthony L Devico
Timothy Fouts
Robert C Gallo
Robert R Redfield
Original Assignee
Univ Maryland Biotech Inst
Alonso Heredia
George Lewis
Anthony L Devico
Timothy Fouts
Robert C Gallo
Robert R Redfield
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Maryland Biotech Inst, Alonso Heredia, George Lewis, Anthony L Devico, Timothy Fouts, Robert C Gallo, Robert R Redfield filed Critical Univ Maryland Biotech Inst
Publication of WO2007011827A2 publication Critical patent/WO2007011827A2/fr
Publication of WO2007011827A3 publication Critical patent/WO2007011827A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention se rapporte à un traitement combiné comprenant des médicaments et/ou des anticorps dirigés contre l'enveloppe virale, combinés à des agents cytostatiques G1 ayant pour activité fonctionnelle de réduire la transcription de CCR5 et entraînant ainsi une réduction du nombre de récepteurs de surface permettant de fixer la glycoprotéine gpl20 du VIH.
PCT/US2006/027584 2005-07-15 2006-07-17 Agents cytostatiques g1 renforçant l'activite antivirale des medicaments et anticorps diriges contre l'enveloppe virale WO2007011827A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69995205P 2005-07-15 2005-07-15
US60/699,952 2005-07-15

Publications (2)

Publication Number Publication Date
WO2007011827A2 WO2007011827A2 (fr) 2007-01-25
WO2007011827A3 true WO2007011827A3 (fr) 2009-06-04

Family

ID=37669446

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/027584 WO2007011827A2 (fr) 2005-07-15 2006-07-17 Agents cytostatiques g1 renforçant l'activite antivirale des medicaments et anticorps diriges contre l'enveloppe virale

Country Status (1)

Country Link
WO (1) WO2007011827A2 (fr)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020155121A1 (en) * 1999-10-08 2002-10-24 Devico Anthony Louis Virus coat protein/receptor chimeras and methods of use
US20050124645A1 (en) * 1998-04-20 2005-06-09 Finkel Terri H. Methods and compositions for increasing CD4lymphocyte immune responsiveness

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050124645A1 (en) * 1998-04-20 2005-06-09 Finkel Terri H. Methods and compositions for increasing CD4lymphocyte immune responsiveness
US20020155121A1 (en) * 1999-10-08 2002-10-24 Devico Anthony Louis Virus coat protein/receptor chimeras and methods of use

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DE ROSNY ET AL.: "Binding of the 2F5 monoclonal antibody to native and fusion-intermediate forms of human immunodeficiency virus type 1 gp41: implications for fusion-inducing conformational changes.", J. VIROL., vol. 78, no. 5, March 2004 (2004-03-01), pages 2627 - 2631 *

Also Published As

Publication number Publication date
WO2007011827A2 (fr) 2007-01-25

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