+

WO2007011434A3 - Methods for treating and preventing cancers that express the hypothalamic-pituitary-gonadal axis of hormones and receptors - Google Patents

Methods for treating and preventing cancers that express the hypothalamic-pituitary-gonadal axis of hormones and receptors Download PDF

Info

Publication number
WO2007011434A3
WO2007011434A3 PCT/US2006/010668 US2006010668W WO2007011434A3 WO 2007011434 A3 WO2007011434 A3 WO 2007011434A3 US 2006010668 W US2006010668 W US 2006010668W WO 2007011434 A3 WO2007011434 A3 WO 2007011434A3
Authority
WO
WIPO (PCT)
Prior art keywords
treating
methods
hypothalamic
pituitary
hormones
Prior art date
Application number
PCT/US2006/010668
Other languages
French (fr)
Other versions
WO2007011434A2 (en
Inventor
Christopher W Gregory
Maria E Kononov
Eric S Werdin
James Lester Barbee Iv
Carol Giamario
Original Assignee
Voyager Pharmaceutical Corp
Christopher W Gregory
Maria E Kononov
Eric S Werdin
James Lester Barbee Iv
Carol Giamario
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/180,667 external-priority patent/US20070015713A1/en
Priority claimed from US11/180,668 external-priority patent/US20060148697A1/en
Application filed by Voyager Pharmaceutical Corp, Christopher W Gregory, Maria E Kononov, Eric S Werdin, James Lester Barbee Iv, Carol Giamario filed Critical Voyager Pharmaceutical Corp
Publication of WO2007011434A2 publication Critical patent/WO2007011434A2/en
Publication of WO2007011434A3 publication Critical patent/WO2007011434A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Reproductive Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Methods are provided for treating HPG axis-positive cancers, preventing or slowing proliferation of cells of HPG axis-positive cancer origin, preventing HPG axis-positive cancers in a patient at risk of contracting such cancers, preventing or inhibiting an upregulation of the cell cycle in HPG axis-positive cancer-derived cells in a patient, and decreasing the level of HPG axis-positive cancer-specific markers in a patient.
PCT/US2006/010668 2005-07-14 2006-03-22 Methods for treating and preventing cancers that express the hypothalamic-pituitary-gonadal axis of hormones and receptors WO2007011434A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US11/180,667 US20070015713A1 (en) 2005-07-14 2005-07-14 Methods for treating prostate cancer
US11/180,668 US20060148697A1 (en) 2001-12-19 2005-07-14 Methods for treating and preventing brain cancers
US11/180,667 2005-07-14
US11/180,668 2005-07-14

Publications (2)

Publication Number Publication Date
WO2007011434A2 WO2007011434A2 (en) 2007-01-25
WO2007011434A3 true WO2007011434A3 (en) 2008-01-10

Family

ID=37669296

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/010668 WO2007011434A2 (en) 2005-07-14 2006-03-22 Methods for treating and preventing cancers that express the hypothalamic-pituitary-gonadal axis of hormones and receptors

Country Status (1)

Country Link
WO (1) WO2007011434A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2090322A1 (en) * 2008-02-18 2009-08-19 INSERM (Institut National de la Santé et de la Recherche Médicale) Use of fsh receptor ligands for diagnosis and therapy of cancer
US8680055B2 (en) * 2009-06-03 2014-03-25 University Of Southern California Methods for decreasing steroidogenesis in prostate cancer cells

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6642274B1 (en) * 1999-09-09 2003-11-04 Gary W. Neal Methods and compositions for preventing and treating prostate disorders

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6642274B1 (en) * 1999-09-09 2003-11-04 Gary W. Neal Methods and compositions for preventing and treating prostate disorders

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
ALLEN ET AL.: "Combined treatment with ketoconazole and luteinising hormone releasing hormone analogue: a novel approach to resistant progressive prostatic cancer", BRITISH MEDICAL JOURNAL, vol. 287, December 1983 (1983-12-01), pages 1766 *
BOLLA ET AL.: "Improved survival in patients with locally advanced prostate cancer treated with radiotherapy and goserelin", N. ENGL. J. MED., vol. 337, no. 5, July 1997 (1997-07-01), pages 295 - 300 *
COOK ET AL.: "Development of GnRH antagonists for prostate cancer: new approaches to treatment", THE ONCOLOGIST, vol. 5, April 2000 (2000-04-01), pages 162 - 168 *
DAWSON ET AL.: "A pilot trial of chemohormonal therapy for metastatic prostate carcinoma", CANCER, vol. 69, no. 1, January 1992 (1992-01-01), pages 213 - 218, XP055002314 *
FISHER ET AL.: "Abarelix Depot (A-D) monotherapy reduces PSA levels comparable to leuprolide acetate (L) plus bicalutamide (B): results of multicenter trial of rising PSA, advanced (D1/D2), neoadjuvant hormonal therapy (NHT), and intermittant hormonal therapy (IHT)....", PROC. AM. SOC. CLIN. ONCOL., vol. 20, 2001 *
UTRIANEN ET AL.: "Inhibition of DNA methylation increases follistatin expression and secretion in the human adrenocortical cell line NCI-H295R", J. OF ENDOCRINOLOGY, vol. 188, 2006, pages 305 - 310 *

Also Published As

Publication number Publication date
WO2007011434A2 (en) 2007-01-25

Similar Documents

Publication Publication Date Title
MX2009008222A (en) Activin-actriia antagonists and uses for treating or preventing breast cancer.
WO2007061874A3 (en) Methods and compositions for use in treating cancer
WO2007149482A3 (en) Xanthohumol based protein kinase modulation cancer treatment
NZ711695A (en) Nanoparticle comprising rapamycin and albumin as anticancer agent
WO2008002672A3 (en) Targets for use in diagnosis, prognosis and therapy of cancer
WO2004034990A3 (en) Methods and compositions for use in treating cancer
IL177346A0 (en) Compositions and methods for characterizing, regulating, diagnosing, and treating cancer
WO2007136790A3 (en) Intracellular kinase inhibitors
WO2009005809A3 (en) Compositions and methods for treating and diagnosing cancer
CA118581S (en) Top divider panel for an office partition
CA124546S (en) Portable electronic multi-media communication device
EP1910936A4 (en) Customizable content creation, management, and delivery system
CA124544S (en) Portable electronic multi-media device
GB0703890D0 (en) Stabilizing crosslinked polymer guars and modified guar derivatives
CA124547S (en) Portable electronic multi-media device
EP1868435A4 (en) Combinations, methods and compositions for treating cancer
WO2008089397A3 (en) Adrb2 cancer markers
GB0519405D0 (en) Cancer therapy prognosis and target
TNSN08401A1 (en) Methods of treating diagnosing or detecting cancer
EP1968981A4 (en) A method of treating tumors with azaxanthones
AU300143S (en) Intercooler
WO2007011434A3 (en) Methods for treating and preventing cancers that express the hypothalamic-pituitary-gonadal axis of hormones and receptors
WO2006123246A3 (en) Methods for identifying chemotherapeutic resistance in non-hematopoietic tumors
GB0413346D0 (en) Treating cancer
WO2008131940A3 (en) Combination of immunological agent and sensitizing agent for the treatment of cancer

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application
NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 06739459

Country of ref document: EP

Kind code of ref document: A2

点击 这是indexloc提供的php浏览器服务，不要输入任何密码和下载