WO2007075269A3 - Method for inhibiting tooth displacement with non-antibacterial tetracyline formulations - Google Patents
Method for inhibiting tooth displacement with non-antibacterial tetracyline formulations Download PDFInfo
- Publication number
- WO2007075269A3 WO2007075269A3 PCT/US2006/046335 US2006046335W WO2007075269A3 WO 2007075269 A3 WO2007075269 A3 WO 2007075269A3 US 2006046335 W US2006046335 W US 2006046335W WO 2007075269 A3 WO2007075269 A3 WO 2007075269A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- antibacterial
- tetracyline
- formulations
- mammal
- tooth displacement
- Prior art date
Links
- 230000000844 anti-bacterial effect Effects 0.000 title abstract 3
- 238000009472 formulation Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 238000006073 displacement reaction Methods 0.000 title abstract 2
- 230000002401 inhibitory effect Effects 0.000 title abstract 2
- 241000124008 Mammalia Species 0.000 abstract 4
- 239000004098 Tetracycline Substances 0.000 abstract 2
- 229960002180 tetracycline Drugs 0.000 abstract 2
- 229930101283 tetracycline Natural products 0.000 abstract 2
- 235000019364 tetracycline Nutrition 0.000 abstract 2
- 150000003522 tetracyclines Chemical class 0.000 abstract 2
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 210000002997 osteoclast Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention relates to a method for inhibiting tooth displacement in a mammal in need thereof comprising administering to the mammal an effective amount of a non-antibacterial tetracycline formulation. The invention also relates to a method for reducing osteoclasts present on alveolar bone surfaces in a mammal in need thereof comprising administering to the mammal an effective amount of a non- antibacterial tetracycline formulation.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75405605P | 2005-12-27 | 2005-12-27 | |
| US60/754,056 | 2005-12-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2007075269A2 WO2007075269A2 (en) | 2007-07-05 |
| WO2007075269A3 true WO2007075269A3 (en) | 2009-04-09 |
Family
ID=38218410
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/US2006/046335 WO2007075269A2 (en) | 2005-12-27 | 2006-12-04 | Method for inhibiting tooth displacement with non-antibacterial tetracyline formulations |
Country Status (1)
| Country | Link |
|---|---|
| WO (1) | WO2007075269A2 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3946290A4 (en) * | 2019-04-04 | 2022-12-21 | CMTX Biotech Inc. | Methods of treating charcot-marie-tooth disease |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6638922B2 (en) * | 1998-11-18 | 2003-10-28 | Collagenex Pharmaceuticals Incorporated | 4-dedimethylaminotetracycline derivatives |
-
2006
- 2006-12-04 WO PCT/US2006/046335 patent/WO2007075269A2/en active Application Filing
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6638922B2 (en) * | 1998-11-18 | 2003-10-28 | Collagenex Pharmaceuticals Incorporated | 4-dedimethylaminotetracycline derivatives |
Non-Patent Citations (2)
| Title |
|---|
| "EUROPEAN ORTHODONTIC SOCIETY 81st Congress, Amsterdam, The Netherlands, June 2005", article BILDT ET AL.: "Inhibition Of Orthodontic Tooth Movement By Chemically Modified Tetracycline-3." * |
| RAMAMURTHY ET AL.: "Inhibition of matrix metalloproteinase-mediated periodontal bone loss in : rats: a comparison of 6 chemically modified tetracyclines.", J. PERIODONTOL., vol. 73, no. 7, July 2002 (2002-07-01), pages 726 - 34 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007075269A2 (en) | 2007-07-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
| NENP | Non-entry into the national phase |
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| 122 | Ep: pct application non-entry in european phase |
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