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WO2007041340A3 - Cellules microfluidiques a arrangements paralleles de molecules d'adn individuelles - Google Patents

Cellules microfluidiques a arrangements paralleles de molecules d'adn individuelles Download PDF

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Publication number
WO2007041340A3
WO2007041340A3 PCT/US2006/038131 US2006038131W WO2007041340A3 WO 2007041340 A3 WO2007041340 A3 WO 2007041340A3 US 2006038131 W US2006038131 W US 2006038131W WO 2007041340 A3 WO2007041340 A3 WO 2007041340A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acid
dna molecules
individual dna
parallel arrays
arrays
Prior art date
Application number
PCT/US2006/038131
Other languages
English (en)
Other versions
WO2007041340A2 (fr
Inventor
Eric C Greene
Original Assignee
Univ Columbia
Eric C Greene
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Columbia, Eric C Greene filed Critical Univ Columbia
Publication of WO2007041340A2 publication Critical patent/WO2007041340A2/fr
Publication of WO2007041340A3 publication Critical patent/WO2007041340A3/fr
Priority to US12/058,095 priority Critical patent/US20080274905A1/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458—Fluorescence microscopy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Optics & Photonics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention concerne des arrangements d'acides nucléiques et des procédés d'utilisation d'arrangements d'acides nucléiques.
PCT/US2006/038131 2005-09-30 2006-09-29 Cellules microfluidiques a arrangements paralleles de molecules d'adn individuelles WO2007041340A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US12/058,095 US20080274905A1 (en) 2005-09-30 2008-03-28 Microfluidic cells with parallel arrays of individual dna molecules

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72273305P 2005-09-30 2005-09-30
US60/722,733 2005-09-30

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US12/058,095 Continuation-In-Part US20080274905A1 (en) 2005-09-30 2008-03-28 Microfluidic cells with parallel arrays of individual dna molecules

Publications (2)

Publication Number Publication Date
WO2007041340A2 WO2007041340A2 (fr) 2007-04-12
WO2007041340A3 true WO2007041340A3 (fr) 2007-11-01

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/038131 WO2007041340A2 (fr) 2005-09-30 2006-09-29 Cellules microfluidiques a arrangements paralleles de molecules d'adn individuelles

Country Status (2)

Country Link
US (1) US20080274905A1 (fr)
WO (1) WO2007041340A2 (fr)

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US8039817B2 (en) 2008-05-05 2011-10-18 Illumina, Inc. Compensator for multiple surface imaging
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WO2010111656A2 (fr) * 2009-03-27 2010-09-30 Life Technologies Corporation Systèmes et procédés d'évaluation d'images
US20110014612A1 (en) 2009-03-27 2011-01-20 Life Technologies Corporation Polymerase compositions & methods
CA2808576A1 (fr) 2009-09-30 2011-04-07 Quantapore, Inc. Sequencage ultrarapide de polymeres biologiques au moyen de nanopores marques
US20120288852A1 (en) * 2010-01-15 2012-11-15 Richard Willson Force Mediated Assays
EP2542900B1 (fr) 2010-03-01 2022-04-20 Ecole Polytechnique Fédérale de Lausanne (EPFL) Appareil et procédé pour la détection et la mesure d'intéractions biomoléculaires
WO2011109368A2 (fr) 2010-03-01 2011-09-09 Cornell University Structuration de biomatériaux à l'aide de matériaux fluorés et de solvants fluorés
US8865404B2 (en) * 2010-11-05 2014-10-21 President And Fellows Of Harvard College Methods for sequencing nucleic acid molecules
WO2012121756A1 (fr) * 2011-03-04 2012-09-13 Quantapore, Inc. Appareil et procédé pour effectuer la détection ou le séquençage optique de nanopores
WO2012170560A2 (fr) * 2011-06-06 2012-12-13 Cornell University Dispositif microfluidique pour l'extraction, l'isolement et l'analyse d'adn provenant de cellules
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US20150018245A1 (en) * 2012-03-21 2015-01-15 Arrayomics, Inc. Lipid arrays on fabricated devices and uses thereof
US20140216935A1 (en) * 2012-08-08 2014-08-07 Lehigh University Dielectrophoretic Tweezers as a Platform for Molecular Force Spectroscopy in a Highly Parallel Format
JP6093540B2 (ja) * 2012-10-18 2017-03-08 株式会社日立ハイテクノロジーズ 荷電粒子線装置内の異物除去方法、及び荷電粒子線装置
US9651539B2 (en) 2012-10-28 2017-05-16 Quantapore, Inc. Reducing background fluorescence in MEMS materials by low energy ion beam treatment
WO2014099057A1 (fr) * 2012-12-21 2014-06-26 The Trustees Of Columbia University In The City Of New York Bicouches lipidiques pour organisation de molécules d'adn et leur utilisation
WO2014186238A1 (fr) * 2013-05-11 2014-11-20 The Board Of Trustees Of The Leland Stanford Junior University Collocation persistante en imagerie par serie temporelle
KR101482624B1 (ko) * 2013-05-16 2015-01-19 한국과학기술연구원 수계 내 표적 유해물질 연속 모니터링 장치 및 방법
WO2014190322A2 (fr) 2013-05-24 2014-11-27 Quantapore, Inc. Analyse d'acides nucléiques basés sur des nanopores avec une détection par fret mixte
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US9352315B2 (en) * 2013-09-27 2016-05-31 Taiwan Semiconductor Manufacturing Company, Ltd. Method to produce chemical pattern in micro-fluidic structure
SG11201702707QA (en) * 2014-09-02 2017-04-27 Bionano Genomics Inc Photocleavage method and apparatus to clean fluidic devices
CN107109472B (zh) 2014-10-10 2021-05-11 昆塔波尔公司 利用互相猝灭的荧光标记物的基于纳米孔的聚合物分析
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CN110907651B (zh) * 2019-12-12 2021-08-20 中国科学院长春应用化学研究所 基于苝衍生物探针自组装的用于蛋白质区分检测的荧光传感器阵列
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Publication number Publication date
WO2007041340A2 (fr) 2007-04-12
US20080274905A1 (en) 2008-11-06

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