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WO2006125025A3 - Matrices extracellulaires de synthese regulant le comportement des cellules souches - Google Patents

Matrices extracellulaires de synthese regulant le comportement des cellules souches Download PDF

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Publication number
WO2006125025A3
WO2006125025A3 PCT/US2006/019130 US2006019130W WO2006125025A3 WO 2006125025 A3 WO2006125025 A3 WO 2006125025A3 US 2006019130 W US2006019130 W US 2006019130W WO 2006125025 A3 WO2006125025 A3 WO 2006125025A3
Authority
WO
WIPO (PCT)
Prior art keywords
stem cell
cell behavior
extracellular matrices
control stem
engineered extracellular
Prior art date
Application number
PCT/US2006/019130
Other languages
English (en)
Other versions
WO2006125025A2 (fr
Inventor
Sherry L Voytik-Harbin
Beverly Z Waisner
Original Assignee
Purdue Research Foundation
Sherry L Voytik-Harbin
Beverly Z Waisner
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purdue Research Foundation, Sherry L Voytik-Harbin, Beverly Z Waisner filed Critical Purdue Research Foundation
Priority to AU2006247228A priority Critical patent/AU2006247228B2/en
Priority to CA2608422A priority patent/CA2608422C/fr
Priority to GB0724345A priority patent/GB2441268B/en
Publication of WO2006125025A2 publication Critical patent/WO2006125025A2/fr
Publication of WO2006125025A3 publication Critical patent/WO2006125025A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3834—Cells able to produce different cell types, e.g. hematopoietic stem cells, mesenchymal stem cells, marrow stromal cells, embryonic stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Transplantation (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Biophysics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)

Abstract

L'invention concerne une composition permettant la culture de cellules souches. Cette composition comprend une matrice de synthèse à base de collagène purifié, qui a été formée dans des conditions contrôlées, de manière à présenter la microstructure et les caractéristiques mécaniques recherchées. Ces compositions de matrice de synthèse à base de collagène purifié peuvent être utilisées seules ou combinées à des cellules, en tant que greffon tissulaire reconstitué, pour favoriser la réparation de tissus endommagés ou malades.
PCT/US2006/019130 2005-05-16 2006-05-16 Matrices extracellulaires de synthese regulant le comportement des cellules souches WO2006125025A2 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2006247228A AU2006247228B2 (en) 2005-05-16 2006-05-16 Engineered extracellular matrices control stem cell behavior
CA2608422A CA2608422C (fr) 2005-05-16 2006-05-16 Matrices extracellulaires de synthese regulant le comportement des cellules souches
GB0724345A GB2441268B (en) 2005-05-16 2006-05-16 Engineered extracellular matrices control stem cell behavior

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US68127805P 2005-05-16 2005-05-16
US68151105P 2005-05-16 2005-05-16
US68152205P 2005-05-16 2005-05-16
US68168905P 2005-05-16 2005-05-16
US60/681,278 2005-05-16
US60/681,511 2005-05-16
US60/681,522 2005-05-16
US60/681,689 2005-05-16

Publications (2)

Publication Number Publication Date
WO2006125025A2 WO2006125025A2 (fr) 2006-11-23
WO2006125025A3 true WO2006125025A3 (fr) 2007-06-07

Family

ID=37106236

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/019130 WO2006125025A2 (fr) 2005-05-16 2006-05-16 Matrices extracellulaires de synthese regulant le comportement des cellules souches

Country Status (4)

Country Link
AU (1) AU2006247228B2 (fr)
CA (1) CA2608422C (fr)
GB (1) GB2441268B (fr)
WO (1) WO2006125025A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12274808B2 (en) 2022-06-30 2025-04-15 Purdue Research Foundation Collagen-based therapeutic delivery systems

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070269476A1 (en) 2006-05-16 2007-11-22 Voytik-Harbin Sherry L Engineered extracellular matrices control stem cell behavior
GB2453452B (en) * 2006-05-16 2010-12-01 Purdue Research Foundation Three dimensional purified collagen matrices
CA2663722C (fr) 2006-09-21 2014-12-09 Purdue Research Foundation Preparation collagene et methode d'isolement
US9867905B2 (en) 2007-12-10 2018-01-16 Purdue Research Foundation Collagen-based matrices with stem cells
US9878071B2 (en) 2013-10-16 2018-01-30 Purdue Research Foundation Collagen compositions and methods of use
WO2016172365A1 (fr) 2015-04-21 2016-10-27 Purdue Research Foundation Office Of Technology Commercialization Composites de cellule-collagène-silice et procédés de fabrication et d'utilisation correspondants
WO2018200750A1 (fr) 2017-04-25 2018-11-01 Purdue Research Foundation Muscle artificiel tridimensionnel (3d) de restauration tissulaire
CN109224129B (zh) * 2018-09-30 2021-09-24 四川大学华西医院 一种皮肤缺损修复材料
US20230119502A1 (en) * 2020-03-30 2023-04-20 Northeastern University Collagen Nucleation Inhibitors

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002102237A2 (fr) * 2001-06-15 2002-12-27 The Cleveland Clinic Foundation Cordes de valvule mitrale obtenues par genie tissulaire; methodes de realisation et d'utilisation
WO2003068287A1 (fr) * 2002-02-11 2003-08-21 Neocutis Sa Compositions comprenant des cellules embryonnaires indifferenciees destinees au traitement d'affections de la peau
WO2003087337A2 (fr) * 2002-04-12 2003-10-23 Yale University Equivalent de peau humaine vascularisee
WO2006003442A2 (fr) * 2004-07-05 2006-01-12 Ucl Business Plc Fabrication independante des cellules d'equivalents tissulaires
EP1674116A2 (fr) * 2004-12-22 2006-06-28 DePuy Products, Inc. Matrice de protéines auto-assemblante obtenue à partir de matrices extracellulaires naturelles

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7615373B2 (en) * 1999-02-25 2009-11-10 Virginia Commonwealth University Intellectual Property Foundation Electroprocessed collagen and tissue engineering

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002102237A2 (fr) * 2001-06-15 2002-12-27 The Cleveland Clinic Foundation Cordes de valvule mitrale obtenues par genie tissulaire; methodes de realisation et d'utilisation
WO2003068287A1 (fr) * 2002-02-11 2003-08-21 Neocutis Sa Compositions comprenant des cellules embryonnaires indifferenciees destinees au traitement d'affections de la peau
WO2003087337A2 (fr) * 2002-04-12 2003-10-23 Yale University Equivalent de peau humaine vascularisee
WO2006003442A2 (fr) * 2004-07-05 2006-01-12 Ucl Business Plc Fabrication independante des cellules d'equivalents tissulaires
EP1674116A2 (fr) * 2004-12-22 2006-06-28 DePuy Products, Inc. Matrice de protéines auto-assemblante obtenue à partir de matrices extracellulaires naturelles

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BRIGHTMAN ET AL.: "Time-lapse confocal reflection microscopy of collagen fibrillogenesis and extracellular matrix assembly in vitro", BIOPOLYMERS, vol. 54, 2000, pages 222 - 234, XP002428748 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12274808B2 (en) 2022-06-30 2025-04-15 Purdue Research Foundation Collagen-based therapeutic delivery systems

Also Published As

Publication number Publication date
GB2441268B (en) 2009-10-21
WO2006125025A2 (fr) 2006-11-23
AU2006247228A1 (en) 2006-11-23
GB2441268A (en) 2008-02-27
CA2608422A1 (fr) 2006-11-23
CA2608422C (fr) 2014-10-28
GB0724345D0 (en) 2008-01-30
AU2006247228B2 (en) 2012-04-26

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