WO2006120525A3 - Processes for the preparation of nelfinavir and new crystalline form of nelfinavir mesylate - Google Patents
Processes for the preparation of nelfinavir and new crystalline form of nelfinavir mesylate Download PDFInfo
- Publication number
- WO2006120525A3 WO2006120525A3 PCT/IB2006/001132 IB2006001132W WO2006120525A3 WO 2006120525 A3 WO2006120525 A3 WO 2006120525A3 IB 2006001132 W IB2006001132 W IB 2006001132W WO 2006120525 A3 WO2006120525 A3 WO 2006120525A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- nelfinavir
- preparation
- crystalline form
- processes
- mesylate
- Prior art date
Links
- 229960005230 nelfinavir mesylate Drugs 0.000 title abstract 4
- NQHXCOAXSHGTIA-SKXNDZRYSA-N nelfinavir mesylate Chemical compound CS(O)(=O)=O.CC1=C(O)C=CC=C1C(=O)N[C@H]([C@H](O)CN1[C@@H](C[C@@H]2CCCC[C@@H]2C1)C(=O)NC(C)(C)C)CSC1=CC=CC=C1 NQHXCOAXSHGTIA-SKXNDZRYSA-N 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- QAGYKUNXZHXKMR-UHFFFAOYSA-N CPD000469186 Natural products CC1=C(O)C=CC=C1C(=O)NC(C(O)CN1C(CC2CCCCC2C1)C(=O)NC(C)(C)C)CSC1=CC=CC=C1 QAGYKUNXZHXKMR-UHFFFAOYSA-N 0.000 title abstract 2
- 229960000884 nelfinavir Drugs 0.000 title abstract 2
- QAGYKUNXZHXKMR-HKWSIXNMSA-N nelfinavir Chemical compound CC1=C(O)C=CC=C1C(=O)N[C@H]([C@H](O)CN1[C@@H](C[C@@H]2CCCC[C@@H]2C1)C(=O)NC(C)(C)C)CSC1=CC=CC=C1 QAGYKUNXZHXKMR-HKWSIXNMSA-N 0.000 title abstract 2
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention relates to a novel crystalline form of nelfinavir mesylate and processes for its preparation. More particularly, it relates to the preparation of crystalline form of nelfinavir mesylate designated as Form I. The invention also relates to pharmaceutical compositions that include the crystalline Form I of nelfinavir mesylate and use of said compositions for treatment of HTV-I infections. The invention also relates to a process for the preparation of nelfinavir or a salt thereof.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1103/DEL/2005 | 2005-05-03 | ||
| IN1103DE2005 | 2005-05-03 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2006120525A2 WO2006120525A2 (en) | 2006-11-16 |
| WO2006120525A3 true WO2006120525A3 (en) | 2007-05-10 |
Family
ID=37396928
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/IB2006/001132 WO2006120525A2 (en) | 2005-05-03 | 2006-05-03 | Processes for the preparation of nelfinavir and new crystalline form of nelfinavir mesylate |
Country Status (1)
| Country | Link |
|---|---|
| WO (1) | WO2006120525A2 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006120525A2 (en) * | 2005-05-03 | 2006-11-16 | Ranbaxy Laboratories Limited | Processes for the preparation of nelfinavir and new crystalline form of nelfinavir mesylate |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006021964A2 (en) * | 2004-08-23 | 2006-03-02 | Matrix Laboratories Ltd | Novel crystalline forms of nelfinavir mesylate |
| WO2006120525A2 (en) * | 2005-05-03 | 2006-11-16 | Ranbaxy Laboratories Limited | Processes for the preparation of nelfinavir and new crystalline form of nelfinavir mesylate |
-
2006
- 2006-05-03 WO PCT/IB2006/001132 patent/WO2006120525A2/en active Application Filing
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006021964A2 (en) * | 2004-08-23 | 2006-03-02 | Matrix Laboratories Ltd | Novel crystalline forms of nelfinavir mesylate |
| WO2006120525A2 (en) * | 2005-05-03 | 2006-11-16 | Ranbaxy Laboratories Limited | Processes for the preparation of nelfinavir and new crystalline form of nelfinavir mesylate |
Non-Patent Citations (1)
| Title |
|---|
| LONGER M: "FORMULATION DEVELOPMENT AND EVALUATION OF VIRACEPTTM (NELFINAVIR MESYLATE) TABLETS", PHARMACEUTICAL RESEARCH, NEW YORK, NY, US, vol. 13, no. 9, SUPPL, 1996, pages S - 349, XP008015125, ISSN: 0724-8741 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006120525A2 (en) | 2006-11-16 |
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