+

WO2006120563A3 - Agents antibacteriens - Google Patents

Agents antibacteriens Download PDF

Info

Publication number
WO2006120563A3
WO2006120563A3 PCT/IB2006/001276 IB2006001276W WO2006120563A3 WO 2006120563 A3 WO2006120563 A3 WO 2006120563A3 IB 2006001276 W IB2006001276 W IB 2006001276W WO 2006120563 A3 WO2006120563 A3 WO 2006120563A3
Authority
WO
WIPO (PCT)
Prior art keywords
compounds
antibacterial agents
methods
pharmaceutical compositions
antibacterial
Prior art date
Application number
PCT/IB2006/001276
Other languages
English (en)
Other versions
WO2006120563A2 (fr
Inventor
Michael Robert Barbachyn
Paul Joseph Dobrowolski
Susan Elizabeth Hagen
Tycho Heinar Heimbach
Alexander Ross Hurd
Timothy Allen Johnson
Dennis Joseph Mcnamara
James Craig Ruble
Debra Ann Sherry
Lisa Marie Thomasco
Peter Laurence Toogood
Original Assignee
Warner Lambert Co
Michael Robert Barbachyn
Paul Joseph Dobrowolski
Susan Elizabeth Hagen
Tycho Heinar Heimbach
Alexander Ross Hurd
Timothy Allen Johnson
Dennis Joseph Mcnamara
James Craig Ruble
Debra Ann Sherry
Lisa Marie Thomasco
Peter Laurence Toogood
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co, Michael Robert Barbachyn, Paul Joseph Dobrowolski, Susan Elizabeth Hagen, Tycho Heinar Heimbach, Alexander Ross Hurd, Timothy Allen Johnson, Dennis Joseph Mcnamara, James Craig Ruble, Debra Ann Sherry, Lisa Marie Thomasco, Peter Laurence Toogood filed Critical Warner Lambert Co
Priority to JP2008510667A priority Critical patent/JP2008543739A/ja
Priority to CA002606847A priority patent/CA2606847A1/fr
Priority to EP06755883A priority patent/EP1888597A2/fr
Publication of WO2006120563A2 publication Critical patent/WO2006120563A2/fr
Publication of WO2006120563A3 publication Critical patent/WO2006120563A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/20—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

L'invention concerne des composés antibactériens, des méthodes pour fabriquer ces composés, des compositions pharmaceutiques contenant ces composés et des méthodes de traitement d'infections bactériennes faisant appel aux composés et aux compositions pharmaceutiques de l'invention.
PCT/IB2006/001276 2005-05-09 2006-04-27 Agents antibacteriens WO2006120563A2 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2008510667A JP2008543739A (ja) 2005-05-09 2006-04-27 抗菌剤
CA002606847A CA2606847A1 (fr) 2005-05-09 2006-04-27 Agents antibacteriens
EP06755883A EP1888597A2 (fr) 2005-05-09 2006-04-27 Agents antibacteriens

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67918505P 2005-05-09 2005-05-09
US60/679,185 2005-05-09

Publications (2)

Publication Number Publication Date
WO2006120563A2 WO2006120563A2 (fr) 2006-11-16
WO2006120563A3 true WO2006120563A3 (fr) 2007-04-12

Family

ID=37396935

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2006/001276 WO2006120563A2 (fr) 2005-05-09 2006-04-27 Agents antibacteriens

Country Status (4)

Country Link
EP (1) EP1888597A2 (fr)
JP (1) JP2008543739A (fr)
CA (1) CA2606847A1 (fr)
WO (1) WO2006120563A2 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DOP2006000268A (es) 2005-12-22 2007-07-31 Pfizer Prod Inc Agentes antibacterianos
JP2010531868A (ja) * 2007-07-02 2010-09-30 アストラゼネカ アクチボラグ ３−スピロピリミジントリオン−キノリン誘導体と抗菌剤としてのその使用
EP2178876A1 (fr) 2007-07-16 2010-04-28 AstraZeneca AB Dérivés d'acide barbiturique spiro-condensés destinés à être utilisés comme antibactériens
CA2736335C (fr) * 2008-10-14 2017-05-09 Astrazeneca Ab Composes heteroaromatiques spirocycliques fusionnes pour traiter les infections bacteriennes
US9040528B2 (en) 2008-10-14 2015-05-26 Astrazeneca Ab Chemical compounds 542
CN102417505B (zh) * 2011-08-29 2014-07-09 南开大学 含甲基-1，2，3-噻二唑的四氮唑类化合物及其制备方法和用途
CN102633746A (zh) * 2012-04-05 2012-08-15 南开大学 含5-甲基-1,2,3-噻二唑的双酰肼衍生物及其制备方法和用途
CN102603670A (zh) * 2012-04-05 2012-07-25 南开大学 一类4-(4-甲基-1，2，3-噻二唑-5-基)-3-烯-2-酮衍生物及其制备方法和用途
CN102633745B (zh) * 2012-04-05 2014-06-18 南开大学 一类α-甲氧亚氨基-4-甲基-1,2,3-噻二唑-5-甲基羧酸酯衍生物及其制备方法和用途
US8952149B2 (en) 2012-09-26 2015-02-10 Zoetis Llc Tricyclic tetrahydroquinoline antibacterial agents
US8889671B2 (en) * 2013-01-23 2014-11-18 Astrazeneca Ab Compounds and methods for treating bacterial infections
SG11201609404SA (en) 2014-05-29 2016-12-29 Entasis Therapeutics Ltd Fused, spirocyclic heteroaromatic compounds for the treatment of bacterial infections
CN108101860B (zh) * 2018-02-08 2021-11-23 苏州敬业医药化工有限公司 顺式-2，6-二甲基吗啉的制备方法
CN113429493B (zh) * 2021-06-29 2022-06-17 吉祥三宝高科纺织有限公司 一种非释放型高分子抗菌防螨剂的制备方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004031195A1 (fr) * 2002-10-07 2004-04-15 Pharmacia & Upjohn Company Llc Agents anti-bacteriens a base de tetrahydroquinoline tricyclique

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004031195A1 (fr) * 2002-10-07 2004-04-15 Pharmacia & Upjohn Company Llc Agents anti-bacteriens a base de tetrahydroquinoline tricyclique

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
PATANI G A ET AL: "BIOISOSTERISM: A RATIONAL APPROACH IN DRUG DESIGN", CHEMICAL REVIEWS, ACS,WASHINGTON, DC, US, vol. 96, no. 8, 1996, pages 3147 - 3176, XP000652176, ISSN: 0009-2665 *
WERMUTH ET AL: "Molecular variations based on isosteric replacements", PRACTICE OF MEDICINAL CHEMISTRY, 1996, pages 203 - 237, XP002190259 *

Also Published As

Publication number Publication date
EP1888597A2 (fr) 2008-02-20
JP2008543739A (ja) 2008-12-04
WO2006120563A2 (fr) 2006-11-16
CA2606847A1 (fr) 2006-11-16

Similar Documents

Publication Publication Date Title
WO2006120563A3 (fr) Agents antibacteriens
TW200734344A (en) Antibacterial agents
WO2008115281A3 (fr) Composés de traitement d'infections virales
WO2007067559A3 (fr) Agents antibacteriens
WO2006086562A3 (fr) Derives de phenylazetidinone
WO2004074244A3 (fr) Composes de pyrimidine
WO2007028135A3 (fr) Composes a base d'imidazopyridine
WO2006087543A8 (fr) Composés antibactériens dérivés de pipéridine
EP1868628A4 (fr) Composes, compositions et methodes de traitement des infections a poxvirus
MX2009005603A (es) Compuestos de urea policiclicos antibacterianos.
MX2009004707A (es) Piridina carboxamides como inhibidores 11-beta-hsd1.
WO2007085852A3 (fr) Matieres antimicrobiennes
WO2008020229A3 (fr) Composés chimiques
WO2008020227A3 (fr) Composés chimiques
WO2007070613A3 (fr) Analogues de la rifamycine et leurs utilisations
WO2007118130A3 (fr) Agents antibactériens
EP1594444A3 (fr) Methodes et compositions destinees au traitement et a la prevention d'infections a staphylocoque ou autres infections bacteriennes
WO2010047737A3 (fr) Composés indoliniques antimicrobiens pour le traitement d'infections bactériennes
WO2007096703A3 (fr) Rifamycines phosphonatées et utilisation pour la prévention des infections des os et des articulations
AP2003002942A0 (en) New derivatives of oxazolidinones as bacterial agents
WO2007089612A3 (fr) Procédés et compositions pour le traitement et la prévention d'infections bactériennes
NZ545472A (en) 7-(4-substituted-3-cyclopropylaminomethyl-1-pyrrolidinyl)quinolonecarboxylic acid derivative
CL2007001542A1 (es) Compuestos derivados de aminotiazoles, composicion farmaceutica; y uso para el tratamiento de infecciones bacterianas.
WO2005089733A3 (fr) Composes anti-adhesifs destines a la prevention et au traitement d'infections bacteriennes
WO2008071961A8 (fr) Dérivés de 2-quinolinone et de 2-quinoxalinone et leur utilisation en tant qu'agents antibactériens

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 2606847

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2008510667

Country of ref document: JP

NENP Non-entry into the national phase

Ref country code: DE

WWW Wipo information: withdrawn in national office

Country of ref document: DE

WWE Wipo information: entry into national phase

Ref document number: 2006755883

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: RU

WWW Wipo information: withdrawn in national office

Country of ref document: RU

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 06755883

Country of ref document: EP

Kind code of ref document: A2

WWP Wipo information: published in national office

Ref document number: 2006755883

Country of ref document: EP

点击 这是indexloc提供的php浏览器服务，不要输入任何密码和下载