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WO2006117534A3 - New use - Google Patents

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Info

Publication number
WO2006117534A3
WO2006117534A3 PCT/GB2006/001582 GB2006001582W WO2006117534A3 WO 2006117534 A3 WO2006117534 A3 WO 2006117534A3 GB 2006001582 W GB2006001582 W GB 2006001582W WO 2006117534 A3 WO2006117534 A3 WO 2006117534A3
Authority
WO
WIPO (PCT)
Prior art keywords
angiotensin
new use
combination
gluccorticosteroid
bronchodilator
Prior art date
Application number
PCT/GB2006/001582
Other languages
French (fr)
Other versions
WO2006117534A2 (en
Inventor
Bertil Lindmark
Anders Thoren
Timothy William Higenbottam
Original Assignee
Astrazeneca Ab
Astrazeneca Uk Ltd
Bertil Lindmark
Anders Thoren
Timothy William Higenbottam
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab, Astrazeneca Uk Ltd, Bertil Lindmark, Anders Thoren, Timothy William Higenbottam filed Critical Astrazeneca Ab
Publication of WO2006117534A2 publication Critical patent/WO2006117534A2/en
Publication of WO2006117534A3 publication Critical patent/WO2006117534A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135—Compounds containing heavy metals
    • A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

New Use The invention provides medicaments comprising a combination of a HMG-CoA reductase inhibitor and a drug intervening in the renin-angiotensin system selected from angiotensin II antagonists and angiotensin converting enzyme (ACE) inhibitors optionally in combination with a bronchodilator and a gluccorticosteroid in the treatment of respiratory disorders such as chronic obstructive pulmonary disease (COPD).
PCT/GB2006/001582 2005-04-30 2006-04-28 New use WO2006117534A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0508924.8A GB0508924D0 (en) 2005-04-30 2005-04-30 New use
GB0508924.8 2005-04-30

Publications (2)

Publication Number Publication Date
WO2006117534A2 WO2006117534A2 (en) 2006-11-09
WO2006117534A3 true WO2006117534A3 (en) 2007-01-25

Family

ID=34674198

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2006/001582 WO2006117534A2 (en) 2005-04-30 2006-04-28 New use

Country Status (2)

Country Link
GB (1) GB0508924D0 (en)
WO (1) WO2006117534A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS53084B (en) 2006-07-05 2014-06-30 Takeda Gmbh Combination of hmg-coa reductase inhibitor rosuvastatin with a phosphodiesterase 4 inhibitor, such as roflumilast, roflumilast-n-oxide for the treatment of inflammatory pulmonary diseases

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0508665A2 (en) * 1991-04-01 1992-10-14 E.R. SQUIBB & SONS, INC. Use of ACE inhibitors for lowering serum cholesterol
US5190970A (en) * 1990-10-19 1993-03-02 E. R. Squibb & Sons, Inc. Method for preventing onset of or treating Type II diabetes employing a cholesterol lowering drug alone or in combination with an ace inhibitor
US20030049314A1 (en) * 2001-08-28 2003-03-13 Liang Matthew H. Treatment of patients at elevated cardiovascular risk with a combination of a cholesterol-lowering agent, an inhibitor of the renin-angiotensin system, and aspirin
US20040039033A1 (en) * 2001-12-10 2004-02-26 Atwal Karnail S. (1-phenyl-2-heteroaryl)ethyl-guanidine compounds as inhibitors of mitochondrial F1F0 ATP hydrolase
US20040043991A1 (en) * 2002-08-13 2004-03-04 Picard Joseph Armand Pyrimidinone fused bicyclic metalloproteinase inhibitors
US20050080087A1 (en) * 2003-10-10 2005-04-14 Annapurna Pendri Pyrazole derivatives as cannabinoid receptor modulators

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5190970A (en) * 1990-10-19 1993-03-02 E. R. Squibb & Sons, Inc. Method for preventing onset of or treating Type II diabetes employing a cholesterol lowering drug alone or in combination with an ace inhibitor
EP0508665A2 (en) * 1991-04-01 1992-10-14 E.R. SQUIBB & SONS, INC. Use of ACE inhibitors for lowering serum cholesterol
US20030049314A1 (en) * 2001-08-28 2003-03-13 Liang Matthew H. Treatment of patients at elevated cardiovascular risk with a combination of a cholesterol-lowering agent, an inhibitor of the renin-angiotensin system, and aspirin
US20040039033A1 (en) * 2001-12-10 2004-02-26 Atwal Karnail S. (1-phenyl-2-heteroaryl)ethyl-guanidine compounds as inhibitors of mitochondrial F1F0 ATP hydrolase
US20040043991A1 (en) * 2002-08-13 2004-03-04 Picard Joseph Armand Pyrimidinone fused bicyclic metalloproteinase inhibitors
US20050080087A1 (en) * 2003-10-10 2005-04-14 Annapurna Pendri Pyrazole derivatives as cannabinoid receptor modulators

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CATTANEO AND REMUZZI: "Lipid oxidative stress and the anti-inflammatory properties of statins", J REN NUTR, vol. 15, no. 1, January 2005 (2005-01-01), pages 71 - 76, XP009073911 *

Also Published As

Publication number Publication date
GB0508924D0 (en) 2005-06-08
WO2006117534A2 (en) 2006-11-09

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