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WO2006039285A3 - Compositions et methodes permettant d'induire l'apoptose des cellules du tissu adipeux - Google Patents

Compositions et methodes permettant d'induire l'apoptose des cellules du tissu adipeux Download PDF

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Publication number
WO2006039285A3
WO2006039285A3 PCT/US2005/034632 US2005034632W WO2006039285A3 WO 2006039285 A3 WO2006039285 A3 WO 2006039285A3 US 2005034632 W US2005034632 W US 2005034632W WO 2006039285 A3 WO2006039285 A3 WO 2006039285A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
adipose tissue
compositions
cell death
tissue cell
Prior art date
Application number
PCT/US2005/034632
Other languages
English (en)
Other versions
WO2006039285A2 (fr
Inventor
Changlong Li
Maryanne Dellafera
Clifton A Baile
Original Assignee
Univ Georgia Res Found
Changlong Li
Maryanne Dellafera
Clifton A Baile
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Georgia Res Found, Changlong Li, Maryanne Dellafera, Clifton A Baile filed Critical Univ Georgia Res Found
Publication of WO2006039285A2 publication Critical patent/WO2006039285A2/fr
Publication of WO2006039285A3 publication Critical patent/WO2006039285A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8962—Allium, e.g. garden onion, leek, garlic or chives

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne des méthodes permettant de traiter l'obésité, des méthodes permettant d'induire l'apoptose des cellules du tissu adipeux chez un hôte, des compositions pharmaceutiques et des méthodes permettant de traiter l'ostéoporose chez un hôte.
PCT/US2005/034632 2004-09-30 2005-09-29 Compositions et methodes permettant d'induire l'apoptose des cellules du tissu adipeux WO2006039285A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61473804P 2004-09-30 2004-09-30
US60/614,738 2004-09-30

Publications (2)

Publication Number Publication Date
WO2006039285A2 WO2006039285A2 (fr) 2006-04-13
WO2006039285A3 true WO2006039285A3 (fr) 2006-06-29

Family

ID=36143004

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/034632 WO2006039285A2 (fr) 2004-09-30 2005-09-29 Compositions et methodes permettant d'induire l'apoptose des cellules du tissu adipeux

Country Status (1)

Country Link
WO (1) WO2006039285A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE508191T1 (de) 2006-11-01 2011-05-15 Medical Res And Infrastructure Fund Of The Tel Aviv Sourasky Medical Ct Adipozytenspezifische konstrukte und verfahren zur hemmung der expression von blutplättchen-typ- 12-lipoxygenase

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050003026A1 (en) * 2002-08-14 2005-01-06 Song-Hae Bok Powder or extracts of plant leaves with anti-obesity effects and anti-obesity food comprising them
US20050013921A1 (en) * 2003-07-17 2005-01-20 Peticca Andrea Lynn Novel multi-component garlic food supplement
US6852343B2 (en) * 2000-10-31 2005-02-08 Pierre Fabre Dermo-Cosmetique Antiadipose topical treatment composition based on garlic bulbs extracts, and cosmetic and therapeutic uses

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6852343B2 (en) * 2000-10-31 2005-02-08 Pierre Fabre Dermo-Cosmetique Antiadipose topical treatment composition based on garlic bulbs extracts, and cosmetic and therapeutic uses
US20050003026A1 (en) * 2002-08-14 2005-01-06 Song-Hae Bok Powder or extracts of plant leaves with anti-obesity effects and anti-obesity food comprising them
US20050013921A1 (en) * 2003-07-17 2005-01-20 Peticca Andrea Lynn Novel multi-component garlic food supplement

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NELSON-DOOLEY C.: "Novel Treatments for Obesity and Osteoporosis: Targeting Apoptotic Pathways in Adipocytes", CURRENT MEDICINAL CHEMISTRY, vol. 12, no. 19, September 2005 (2005-09-01), pages 2215 - 2225, XP008063180 *

Also Published As

Publication number Publication date
WO2006039285A2 (fr) 2006-04-13

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