WO2006039268A3 - Formulations pharmaceutiques renfermant des molecules tpgs de vitamine e solubilisant des medicaments lipophiles sans inhibition importante de l'ecoulement et utilisation de telles formulations - Google Patents
Formulations pharmaceutiques renfermant des molecules tpgs de vitamine e solubilisant des medicaments lipophiles sans inhibition importante de l'ecoulement et utilisation de telles formulations Download PDFInfo
- Publication number
- WO2006039268A3 WO2006039268A3 PCT/US2005/034587 US2005034587W WO2006039268A3 WO 2006039268 A3 WO2006039268 A3 WO 2006039268A3 US 2005034587 W US2005034587 W US 2005034587W WO 2006039268 A3 WO2006039268 A3 WO 2006039268A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- lipophilic drugs
- containing vitamin
- formulations
- efflux inhibition
- pharmaceutical formulations
- Prior art date
Links
- 229940079593 drug Drugs 0.000 title abstract 3
- 239000003814 drug Substances 0.000 title abstract 3
- 230000005764 inhibitory process Effects 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- AOBORMOPSGHCAX-UHFFFAOYSA-N Tocophersolan Chemical compound OCCOC(=O)CCC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C AOBORMOPSGHCAX-UHFFFAOYSA-N 0.000 title 1
- 238000009472 formulation Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000003381 solubilizing effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nutrition Science (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05803721A EP1793806A2 (fr) | 2004-09-30 | 2005-09-29 | Formulations pharmaceutiques renfermant des molecules tpgs de vitamine e solubilisant des medicaments lipophiles sans inhibition importante de l'ecoulement et utilisation de telles formulations |
JP2007534708A JP2008514714A (ja) | 2004-09-30 | 2005-09-29 | 有意な流出阻害を示さない、親油性薬物を可溶化するビタミンetpgs分子を含む医薬製剤及びこのような医薬製剤の使用 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US61489104P | 2004-09-30 | 2004-09-30 | |
US60/614,891 | 2004-09-30 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2006039268A2 WO2006039268A2 (fr) | 2006-04-13 |
WO2006039268A3 true WO2006039268A3 (fr) | 2006-07-27 |
Family
ID=36142996
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2005/034587 WO2006039268A2 (fr) | 2004-09-30 | 2005-09-29 | Formulations pharmaceutiques renfermant des molecules tpgs de vitamine e solubilisant des medicaments lipophiles sans inhibition importante de l'ecoulement et utilisation de telles formulations |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1793806A2 (fr) |
JP (1) | JP2008514714A (fr) |
CN (1) | CN101031284A (fr) |
WO (1) | WO2006039268A2 (fr) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060240051A1 (en) * | 2005-04-26 | 2006-10-26 | Singleton Andy H | Eutectic blends containing a water soluble vitamin derivative |
EP2398476B1 (fr) | 2009-02-23 | 2018-02-07 | Nanorx, Inc. | Nanoparticules de policosanol |
US9034383B2 (en) | 2010-08-23 | 2015-05-19 | NanoRx, Inc. | Policosanol nanoparticles |
GB201115633D0 (en) * | 2011-09-09 | 2011-10-26 | Univ Liverpool | Compositions of efavirenz |
KR20220119647A (ko) * | 2019-12-20 | 2022-08-30 | 아이도시아 파마수티컬즈 리미티드 | N-[1-(5-시아노-피리딘-2-일메틸)-1h-피라졸-3-일]-2-[4-(1-트리플루오로메틸-시클로프로필)-페닐]-아세트아미드를 포함하는 제약 조성물 |
BR112022011786A2 (pt) * | 2019-12-20 | 2022-08-30 | Intervet Int Bv | Composição farmacêutica de pirazol |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997035587A1 (fr) * | 1996-03-22 | 1997-10-02 | Glaxo Group Limited | Compositions contenant un inhibiteur de la protease du vih tel que le vx 478 et un compose hydrosoluble de vitamine e tel que la vitamine e-tpgs |
WO1998008490A1 (fr) * | 1996-09-01 | 1998-03-05 | Pharmos Corporation | Coprecipites solides augmentant la biodisponibilite de substances lipophiles |
WO2000061189A2 (fr) * | 1999-04-02 | 2000-10-19 | National Research Council Of Canada | Compositions hydrosolubles de composes lipophiles bioactifs |
US20010029264A1 (en) * | 1998-03-10 | 2001-10-11 | Mcchesney-Harris Lisa L. | Novel methods and compositions for delivery of taxanes |
WO2003013474A1 (fr) * | 2001-08-09 | 2003-02-20 | Jagotec Ag | Preparations nanoparticulaires constituees de fenofibrate |
US20030191179A1 (en) * | 1999-10-25 | 2003-10-09 | Supergen, Inc. | Methods for administration of paclitaxel |
EP1464341A1 (fr) * | 2003-04-03 | 2004-10-06 | Visufarma S.R.L. | Formulation hydrosoluble comprénant de l'ubiquinone pour utilisation oculaire |
-
2005
- 2005-09-29 EP EP05803721A patent/EP1793806A2/fr not_active Withdrawn
- 2005-09-29 CN CNA2005800332025A patent/CN101031284A/zh active Pending
- 2005-09-29 WO PCT/US2005/034587 patent/WO2006039268A2/fr active Application Filing
- 2005-09-29 JP JP2007534708A patent/JP2008514714A/ja active Pending
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997035587A1 (fr) * | 1996-03-22 | 1997-10-02 | Glaxo Group Limited | Compositions contenant un inhibiteur de la protease du vih tel que le vx 478 et un compose hydrosoluble de vitamine e tel que la vitamine e-tpgs |
WO1998008490A1 (fr) * | 1996-09-01 | 1998-03-05 | Pharmos Corporation | Coprecipites solides augmentant la biodisponibilite de substances lipophiles |
US20010029264A1 (en) * | 1998-03-10 | 2001-10-11 | Mcchesney-Harris Lisa L. | Novel methods and compositions for delivery of taxanes |
WO2000061189A2 (fr) * | 1999-04-02 | 2000-10-19 | National Research Council Of Canada | Compositions hydrosolubles de composes lipophiles bioactifs |
US20030191179A1 (en) * | 1999-10-25 | 2003-10-09 | Supergen, Inc. | Methods for administration of paclitaxel |
WO2003013474A1 (fr) * | 2001-08-09 | 2003-02-20 | Jagotec Ag | Preparations nanoparticulaires constituees de fenofibrate |
EP1464341A1 (fr) * | 2003-04-03 | 2004-10-06 | Visufarma S.R.L. | Formulation hydrosoluble comprénant de l'ubiquinone pour utilisation oculaire |
Also Published As
Publication number | Publication date |
---|---|
CN101031284A (zh) | 2007-09-05 |
EP1793806A2 (fr) | 2007-06-13 |
JP2008514714A (ja) | 2008-05-08 |
WO2006039268A2 (fr) | 2006-04-13 |
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