+

WO2006035669A1 - Stent souple realisant un excellent suivi et une excellente dilatation vasculaires - Google Patents

Stent souple realisant un excellent suivi et une excellente dilatation vasculaires Download PDF

Info

Publication number
WO2006035669A1
WO2006035669A1 PCT/JP2005/017480 JP2005017480W WO2006035669A1 WO 2006035669 A1 WO2006035669 A1 WO 2006035669A1 JP 2005017480 W JP2005017480 W JP 2005017480W WO 2006035669 A1 WO2006035669 A1 WO 2006035669A1
Authority
WO
WIPO (PCT)
Prior art keywords
wave
stent
elements
connecting element
annular members
Prior art date
Application number
PCT/JP2005/017480
Other languages
English (en)
Japanese (ja)
Inventor
Yoshihiko Sano
Yuji Tanaka
Yukinori Ebara
Original Assignee
Nipro Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nipro Corporation filed Critical Nipro Corporation
Publication of WO2006035669A1 publication Critical patent/WO2006035669A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/91508—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other the meander having a difference in amplitude along the band
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/91516—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other the meander having a change in frequency along the band
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/91533—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other characterised by the phase between adjacent bands
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/9155—Adjacent bands being connected to each other
    • A61F2002/91558—Adjacent bands being connected to each other connected peak to peak
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0004—Rounded shapes, e.g. with rounded corners
    • A61F2230/0013—Horseshoe-shaped, e.g. crescent-shaped, C-shaped, U-shaped

Definitions

  • the present invention relates to a so-called stent that is implanted in a living body for the purpose of maintaining the lumen diameter of a body lumen such as a blood vessel.
  • a stent has been adopted in order to expand the diameter of a lumen of a blood vessel or the like and maintain the size of the obtained lumen.
  • Stent expansion methods include balloon expansion, self-expansion using shape memory materials, and mechanical expansion, but expansion using nolane is common.
  • the stent is introduced to a desired position on the body together with a non-renal catheter, and is expanded by balloon inflation to expand the lumen diameter.
  • the stent usually has a lumen diameter holding portion that expands and holds the lumen diameter of a blood vessel and the like, and a joint portion force that connects them in the longitudinal direction, and the expanded shape is maintained.
  • a stent having a lumen diameter holding part and a joint part force As such a stent having a lumen diameter holding part and a joint part force, a plurality of cylindrical elements that can be expanded independently in the radial direction are connected so as to be substantially aligned with a common axis (Patent Document 1). Or a radially extending tubular member formed by a plurality of elongated members intersecting each other (Patent Document 2), or a plurality of substantially connected integrally at the axial bending portion.
  • a straight and overlapping structure comprising at least two single wire-like circular members bent so as to form a segment, and the circular members are firmly connected to each other by a shaft bending portion (Patent Document 3), Consists of a tube with a pattern shape having first and second meander patterns having axes extending in the first and second directions (Patent Document 4), and a plurality of cylindrical segments are gathered by interconnecting elements in oblique directions. The ends are joined Those posts or Ranaru open structure type is (Patent Document 5), and the proposed! Ru.
  • Patent Document 1 Japanese Patent Laid-Open No. 6-181993
  • Patent Document 2 Japanese Patent Laid-Open No. 62-231657
  • Patent Document 3 Japanese Patent Laid-Open No. 8-155035
  • Patent Document 4 Japanese Unexamined Patent Publication No. 10-503676
  • Patent Document 5 Japanese Patent Publication No. 11-505441
  • the present invention has been made in view of the above circumstances, and is excellent in followability to a lumen or the like (and thus can pass through a three-dimensionally meandering lumen), and substantially causes shortening.
  • the present invention provides a flexible stent having excellent extensibility and capable of forming a lateral hole in a stent. Means for solving the problem
  • the stent of the present invention comprises a plurality of radially expandable annular members arranged in the longitudinal axis direction and a plurality of connecting elements that connect the adjacent annular members in the longitudinal axis direction.
  • a wave element consisting of one wave crest and one wave trough force is continuously repeated in a meandering pattern in the circumferential direction, and adjacent annular members are adjacent to the wave front of the wave element or the wave element.
  • the wave-like elements are connected to each other in the vicinity of the wave front, and in the unfolded state, the wave-like wave connected by the connection element has a relatively small amplitude.
  • connection between the adjacent annular members can be arbitrarily determined, but specifically, the connection between the adjacent annular members is preferably performed every even number of the wave elements. Preferably, every other, four or every six wavy elements are carried out. And it is preferable that the wave fronts connected by the connecting elements of the adjacent annular members are positioned on the same straight line in the longitudinal direction. In addition, the amplitude of the waves connected by the connecting elements that are preferably connected on the same straight line in the longitudinal direction between adjacent annular members does not substantially cause shortening when the stent is expanded. , Waves not connected by connecting elements Preferably, the amplitude is 1: 2 to 7: 8.
  • the amplitude of the wave connected by the connecting element is reduced, and in order to reduce the shortening at this time, the wavelength of the wave connected by the connecting element is the wavelength not connected by the connecting element. (The longer the coupling element, the better the flexibility. However, if the amplitude is reduced to make the coupling element longer, the shortening during expansion will increase).
  • the shape of the connecting element can be either a straight line or a curved line. If the connecting element is a curved line, even if there is only one wave peak that is preferred to be wavy, There can be one or more waves, and there can be multiple peaks and valleys.
  • stainless steel As a material for forming the stent, stainless steel, tungsten, tantalum, nickel titanium alloy and the like can be employed.
  • a wave peak means a wave convex right (convex to the tip side), and a wave valley means a wave convex left (convex to the base end side).
  • the annular member constituting the tube wall of the stent also has a meandering pattern force of the wavy element (unit pattern), so the entire stent is flexible to bending, and therefore follows the lumen etc. Excellent in properties. Also, it is easy to form a horizontal hole.
  • the adjacent annular members are connected by a wave front having a relatively small amplitude, there is substantially no change in the length of the stent during expansion.
  • the adjacent annular members are connected with wave-shaped wave fronts, there is no warping during expansion at the wave front part, and there are also few warpings during bending, so the blood vessels when guiding the stent to the application site Can be avoided as much as possible.
  • FIG. 1 is a plan view of a stent according to an embodiment of the present invention.
  • FIG. 2 is a development view of the stent shown in FIG. 1.
  • FIG. 3 is a plan view showing a state where the stent shown in FIG. 1 is expanded.
  • FIG. 4 is a partially enlarged view of FIG.
  • FIG. 5 is a view showing an example of a connecting element according to the present invention, showing a connected state of annular members.
  • FIG. 6 is a development view of a stent according to another embodiment of the present invention.
  • FIG. 7 is a development view of a stent according to another embodiment of the present invention.
  • FIG. 8 is a development view of a stent according to another embodiment of the present invention.
  • FIG. 9 is a development view of a stent according to another embodiment of the present invention.
  • FIG. 10 is a development view of a stent according to another embodiment of the present invention.
  • FIG. 11 is a development view of a stent according to another embodiment of the present invention.
  • FIG. 12 is a development view of a stent according to another embodiment of the present invention.
  • FIG. 13 is a diagram comparing the flexibility of the stent of the present invention and a conventional stent.
  • FIG. 14 is a diagram comparing the shortening of the stent of the present invention and a conventional stent.
  • FIG. 15 is a diagram comparing the blood vessel diameter retention of the stent of the present invention and a conventional stent.
  • FIG. 16 is a development view of a conventional stent.
  • FIG. 17 is a development view of a conventional stent.
  • FIG. 18 is a development view of a conventional stent.
  • connection between the adjacent connection members is made every four wave-like elements, and the wave fronts of the wave-like elements connected between the adjacent annular members of the wave-like elements are positioned on the same straight line in the longitudinal direction.
  • the adjacent annular members are connected on the same straight line in the longitudinal direction.
  • Ma The amplitude of the wave connected by the connecting element shall be 2Z3 of the amplitude of the wave not connected by the connecting element. Also, the wavelength of the wave connected by the connecting element should be twice that of the wave not connected by the connecting element.
  • Example 1 will be described with reference to FIGS.
  • FIG. 1 is a plan view of a stent according to an embodiment of the present invention
  • FIG. 2 is a development view of the stent shown in FIG. 1
  • FIG. 3 is a plan view showing an expanded state of the stent shown in FIG.
  • FIG. 3 is an enlarged view of a part of FIG.
  • the stent of Example 1 includes 10 annular members 1 arranged in the longitudinal direction for keeping the living body lumen open, and adjacent annular members 1 and 1. Is a tubular member having two connecting elements 2 in the longitudinal direction, and the annular member 1 is composed of ten wavy elements 11 continuous in the circumferential direction, and is expandable in the radial direction. ing.
  • the wavelength of the wave connected by the connecting element 2 is twice the wavelength of the wave not connected by the connecting element 2.
  • the wavy element 11 is composed of one wave peak 111 and one wave valley 11 2, and in the expanded state, the wavy element 11 has a repeated meandering pattern. It is continuous.
  • the adjacent annular members 1 and 1 are connected by two connecting elements 2 having the shape shown in FIG. 5A on the same straight line in the longitudinal direction, and the wave connected by the connecting element 2 is One becomes the Wave Mountain 113 and the other becomes the Wave Valley 114.
  • the wave peak 113 and the wave valley 114 connected by the connecting element 2 have a relatively small wave amplitude, and the wave peak 111 and the wave valley 112 are not connected by the connecting element 2.
  • the amplitude becomes 2Z3.
  • the wavelength of the wave connected by connecting element 2 is twice that of the wave not connected by connecting element 2.
  • the stent of Example 2 has 11 annular members 1 and three connecting elements 2 each having two wavy elements and having a shape as shown in FIG. 5B.
  • the annular member 1 is composed of nine corrugated elements 11 that are continuous in the circumferential direction.
  • the ratio of the amplitude of the wave connected by connecting element 2 to the amplitude of the wave not connected by connecting element 2 is 4Z5.
  • Example 3 of the present invention will be described with reference to FIG.
  • the stent of Example 3 has 11 annular members 1 and three connecting elements 2 having a shape as shown in FIG. 5D provided for every three wavy elements.
  • the annular member 1 is composed of twelve wavy elements 11 that are continuous in the circumferential direction.
  • the ratio of the wave amplitude connected by connecting element 2 to the wave amplitude not connected by connecting element 2 is 7: 8.
  • Example 4 Similar to the one shown in Example 1, there is no warping at the time of expansion at the wave front, and there is little warping at the time of bending, so that damage to the blood vessel when guiding the stent to the application site can be avoided as much as possible. .
  • the shortening during expansion is slightly inferior to that shown in Example 1.
  • the flexibility is slightly better than Example 2 with the same number of connecting elements.
  • Example 4
  • Example 4 of the present invention will be described with reference to FIG.
  • the stent of Example 4 has ten annular members 1 and three connecting elements 2 having a shape as shown in FIG. 5B provided for every four wavy elements.
  • the annular member 1 is composed of 15 corrugated elements 11 continuous in the circumferential direction.
  • the ratio of the wave amplitude connected by connecting element 2 to the wave amplitude not connected by connecting element 2 is 3: 5.
  • Example 5 Similar to the one shown in Example 1, there is no warping at the time of expansion at the wave front, and there is little warping at the time of bending, so that damage to the blood vessel when guiding the stent to the application site can be avoided as much as possible. . There is almost no shortening during expansion. Flexibility is almost the same as Example 1 despite the large number of connecting elements Example 5
  • Example 5 of the present invention will be described with reference to FIG.
  • the stent of Example 5 has ten annular members 1 and two connecting elements 2 having a shape as shown in FIG. 5A provided for every six wavy elements.
  • the annular member 1 is composed of 14 corrugated elements 11 continuous in the circumferential direction.
  • the ratio of the amplitude of the wave connected by connecting element 2 to the amplitude of the wave not connected by connecting element 2 is 3: 4.
  • Example 1 Similar to the one shown in Example 1, there is no warping at the time of expansion at the wave front, and there is little warping at the time of bending, so that damage to the blood vessel when guiding the stent to the application site can be avoided as much as possible. .
  • the shortening during expansion is slightly better than that shown in Example 1.
  • the flexibility is also slightly better than in Example 1 where the number of connecting elements is equal.
  • Example 6 of the present invention will be described with reference to FIG.
  • the stent of Example 6 has 11 annular members 1 and two connecting elements 2 each having two wavy elements and having a shape as shown in FIG. 5A.
  • the annular member 1 is composed of six corrugated elements 11 continuous in the circumferential direction.
  • the ratio of the wave amplitude connected by connecting element 2 and the wave amplitude not connected by connecting element 2 is 3: 5.
  • the shortening at the time of expansion is slightly longer like that shown in the first embodiment.
  • the flexibility is slightly inferior to Example 1 with the same number of connecting elements.
  • Example 7 of the present invention will be described with reference to FIG.
  • the stent of Example 7 has eight annular members 1 and four connecting elements 2 having a shape as shown in FIG. 5C provided every two wavy elements.
  • the annular member 1 is composed of twelve wavy elements 11 that are continuous in the circumferential direction.
  • the ratio of the amplitude of the wave connected by connecting element 2 and the connecting element 2 is not !, the ratio of the amplitude of the wave is 5: 6!
  • Example 8 Similar to the one shown in Example 1, there is no warping at the time of expansion at the wave front, and there is little warping at the time of bending, so that damage to the blood vessel when guiding the stent to the application site can be avoided as much as possible. .
  • the shortening at the time of expansion is the same as that shown in the third embodiment.
  • the number of connecting elements is large, the flexibility is better than that shown in Example 2 because of the long connecting elements. Therefore, the entire stent is flexible with respect to bending, and therefore has excellent followability to a lumen or the like.
  • Example 8 Example 8
  • Example 8 of the present invention will be described with reference to FIG.
  • the stent of Example 8 has eight annular members 1 and two connecting elements 2 having a shape as shown in FIG. 5D provided for every three wavy elements.
  • the annular member 1 is composed of eight wavy elements 11 that are continuous in the circumferential direction.
  • the ratio of the wave amplitude connected by connecting element 2 to the wave amplitude not connected by connecting element 2 is 7: 8.
  • the stent of the present invention has much better flexibility than the conventional stent.
  • Fig. 14 that shortening during expansion can be prevented by appropriately selecting the height of the wave peaks (valley depth) to be connected.
  • FIG. 15 that the blood vessel diameter retention strength is equivalent to that of the conventional stent.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Optics & Photonics (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Physics & Mathematics (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

L’invention concerne un stent réalisant un excellent suivi des lumières (et permettant donc de traverser les lumières en serpentant dans les trois dimensions), évitant essentiellement tout rétrécissement et permettant d’y ménager un trou latéral. Une pièce annulaire (1) comprend dix éléments ondulés (11) se succédant dans la direction circonférentielle de façon à se dilater dans la direction radiale. Chaque élément ondulé (11) comprend la crête (111) d’une ondulation et le creux (112) de l’ondulation. Dans l’état développé des éléments ondulés, ceux-ci forment un motif répété continu qui serpente dans la direction verticale. Les pièces annulaires (1) et (1) adjacentes l’une à l’autre sont reliées sur la même ligne droite longitudinale, et les ondulations reliées par des éléments de liaison (2) présentent chacune une crête (113) et un creux (114). La crête (113) et le creux (114) de l’ondulation sont configurées de façon à ce que les amplitudes de l’ondulation soient réduites les unes par rapport aux autres uniquement au niveau de ces parties, ces amplitudes correspondant aux 2/3 des amplitudes de la crête (111) et du creux (112) des ondulations qui ne sont pas reliées par les éléments de liaison (2).
PCT/JP2005/017480 2004-09-28 2005-09-22 Stent souple realisant un excellent suivi et une excellente dilatation vasculaires WO2006035669A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2004282361 2004-09-28
JP2004-282361 2004-09-28

Publications (1)

Publication Number Publication Date
WO2006035669A1 true WO2006035669A1 (fr) 2006-04-06

Family

ID=36118817

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2005/017480 WO2006035669A1 (fr) 2004-09-28 2005-09-22 Stent souple realisant un excellent suivi et une excellente dilatation vasculaires

Country Status (1)

Country Link
WO (1) WO2006035669A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008112057A3 (fr) * 2007-03-09 2008-10-30 Boston Scient Scimed Inc Modèle de stent avec des entretoises présentant des angles et une rigidité différents
JP2010505533A (ja) * 2006-10-06 2010-02-25 アボット、カーディオバスキュラー、システムズ、インコーポレーテッド 脈管内ステント

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002516704A (ja) * 1998-06-02 2002-06-11 トランスバスキュラー インコーポレイテッド 変形可能な支持用多細胞型ステント
JP2002355315A (ja) * 2001-06-01 2002-12-10 Terumo Corp ステント
JP2003010341A (ja) * 2001-03-02 2003-01-14 Cordis Corp 柔軟性ステント
WO2003057076A1 (fr) * 2001-12-21 2003-07-17 Scmed Life Systems, Inc. Géométrie d'endoprothèse à flexibilité améliorée
WO2003094798A1 (fr) * 2002-05-08 2003-11-20 Abbott Laboratories Endoprothese presentant des extensions formant embases

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002516704A (ja) * 1998-06-02 2002-06-11 トランスバスキュラー インコーポレイテッド 変形可能な支持用多細胞型ステント
JP2003010341A (ja) * 2001-03-02 2003-01-14 Cordis Corp 柔軟性ステント
JP2002355315A (ja) * 2001-06-01 2002-12-10 Terumo Corp ステント
WO2003057076A1 (fr) * 2001-12-21 2003-07-17 Scmed Life Systems, Inc. Géométrie d'endoprothèse à flexibilité améliorée
WO2003094798A1 (fr) * 2002-05-08 2003-11-20 Abbott Laboratories Endoprothese presentant des extensions formant embases

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010505533A (ja) * 2006-10-06 2010-02-25 アボット、カーディオバスキュラー、システムズ、インコーポレーテッド 脈管内ステント
EP2649969A1 (fr) * 2006-10-06 2013-10-16 Abbott Cardiovascular Systems Inc. Endoprothèse intravasculaire
US8778009B2 (en) 2006-10-06 2014-07-15 Abbott Cardiovascular Systems Inc. Intravascular stent
US9402752B2 (en) 2006-10-06 2016-08-02 Abbott Cardiovascular Systems Inc. Intravascular stent
WO2008112057A3 (fr) * 2007-03-09 2008-10-30 Boston Scient Scimed Inc Modèle de stent avec des entretoises présentant des angles et une rigidité différents
US8512392B2 (en) 2007-03-09 2013-08-20 Boston Scientific Scimed, Inc. Stent design with struts of various angles and stiffness

Similar Documents

Publication Publication Date Title
JP4564678B2 (ja) 縦方向に可撓性のステント
JP4817499B2 (ja) 長手方向に柔軟性を有する拡張可能なステント
JP3089124U (ja) 半径方向に拡径可能な支持構造
JP4797473B2 (ja) 拡張性の優れた柔軟なステント
JP4591348B2 (ja) 血管追従性の優れた拡張性のよい柔軟なステント
US20020103529A1 (en) Longitudinally flexible stent
US20100228339A1 (en) Longitudinally flexible stent
JP2000024117A (ja) 半径方向に拡径可能な支持構造
KR20030081411A (ko) 스텐트
WO2004108201A1 (fr) Prothese endovasculaire presentant une excellente capacite de suivi de vaisseau sanguin
US20080215133A1 (en) Longitudinally flexible stent
WO2006035669A1 (fr) Stent souple realisant un excellent suivi et une excellente dilatation vasculaires
CN100591385C (zh) 对血管具有极好跟随能力的可延伸的柔软的支架
JP4569262B2 (ja) 血管追従性および拡張性の優れた柔軟なステント
JP5011604B2 (ja) ステント
US8496699B2 (en) Longitudinally flexible stent
JP2004329790A (ja) 血管追従性・管腔径保持性の優れた柔軟なステント
JP2005013302A (ja) 血管追従性および拡張性のよい、血管に優しい柔軟なステント
JP2005066202A (ja) 血管追従性・拡張性の優れた柔軟なステント
JP2005027923A (ja) 血管追従性と拡張性のよい、血管に優しい柔軟なステント
JP2004329789A (ja) 血管追従性と拡張性の優れたステント
JP2005027909A (ja) 血管追従性・拡張性のよい、血管に優しい柔軟なステント
JP2004275513A (ja) 血管径保持性および血管追従性の優れた柔軟なステント
JP2004305450A (ja) 血管追従性の優れた均一に拡張する柔軟なステント
JP2004321297A (ja) 血管追従性の優れた柔軟なステント

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KM KP KR KZ LC LK LR LS LT LU LV LY MA MD MG MK MN MW MX MZ NA NG NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SM SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LT LU LV MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP

点击 这是indexloc提供的php浏览器服务，不要输入任何密码和下载