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WO2006032844A3 - Particle sorting in a tailored landscape - Google Patents

Particle sorting in a tailored landscape Download PDF

Info

Publication number
WO2006032844A3
WO2006032844A3 PCT/GB2005/003476 GB2005003476W WO2006032844A3 WO 2006032844 A3 WO2006032844 A3 WO 2006032844A3 GB 2005003476 W GB2005003476 W GB 2005003476W WO 2006032844 A3 WO2006032844 A3 WO 2006032844A3
Authority
WO
WIPO (PCT)
Prior art keywords
sorting
landscape
particles
tailored
particle sorting
Prior art date
Application number
PCT/GB2005/003476
Other languages
French (fr)
Other versions
WO2006032844A2 (en
Inventor
Kishan Dholakia
David Mcgloin
Lynn Paterson
Original Assignee
Univ St Andrews
Kishan Dholakia
David Mcgloin
Lynn Paterson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ St Andrews, Kishan Dholakia, David Mcgloin, Lynn Paterson filed Critical Univ St Andrews
Publication of WO2006032844A2 publication Critical patent/WO2006032844A2/en
Publication of WO2006032844A3 publication Critical patent/WO2006032844A3/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0454—Moving fluids with specific forces or mechanical means specific forces radiation pressure, optical tweezers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Electroluminescent Light Sources (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

A method for sorting/separating at least two different particles in a fluid, the method comprising defining within the fluid a static optical landscape/pattern having one or more optical wells or troughs that are substantially the same size or slightly larger than at least one of the particles. By exploiting differing particle responses to the same light pattern, separation/sorting can be done. This type of sorting may potentially be performed to separate particles that are of different sizes, shapes or refractive indices.
PCT/GB2005/003476 2004-09-23 2005-09-09 Particle sorting in a tailored landscape WO2006032844A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0421166.0A GB0421166D0 (en) 2004-09-23 2004-09-23 Particle sorting in a tailored landscape
GB0421166.0 2004-09-23

Publications (2)

Publication Number Publication Date
WO2006032844A2 WO2006032844A2 (en) 2006-03-30
WO2006032844A3 true WO2006032844A3 (en) 2006-07-06

Family

ID=33397133

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2005/003476 WO2006032844A2 (en) 2004-09-23 2005-09-09 Particle sorting in a tailored landscape

Country Status (2)

Country Link
GB (1) GB0421166D0 (en)
WO (1) WO2006032844A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9815058B2 (en) 2003-05-08 2017-11-14 The University Court Of The University Of St Andrews Fractionation of particles
GB0618605D0 (en) 2006-09-21 2006-11-01 Univ St Andrews Optical sorting
GB0618606D0 (en) * 2006-09-21 2006-11-01 Univ St Andrews Optical sorting
GB0815774D0 (en) * 2008-08-29 2008-10-08 Univ St Andrews Optical manipulation
WO2011078375A1 (en) * 2009-12-25 2011-06-30 Sumitomo Chemical Company, Limited Insect pest controlling resin composition
US20150355071A1 (en) 2013-02-04 2015-12-10 Danmarks Tekniske Universitet System for optical sorting of microscopic objects

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002039104A1 (en) * 2000-11-13 2002-05-16 Genoptix, Inc. System and method for separating micro-particles
WO2004025668A2 (en) * 2002-09-16 2004-03-25 University Of Chicago Optical accelerator and generalized optical vortices

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002039104A1 (en) * 2000-11-13 2002-05-16 Genoptix, Inc. System and method for separating micro-particles
WO2004025668A2 (en) * 2002-09-16 2004-03-25 University Of Chicago Optical accelerator and generalized optical vortices

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
CHIOU PEI YU, OTHA AARON T, WU MING C: "Massively parallel manipulation of single cells and microparticles using optical images", NATURE, vol. 436, 21 July 2005 (2005-07-21), pages 370 - 372, XP002367223 *
CHIOU PEI-YU, OTHA AARON T, WU MING C: "Toward all optical lab-on-chip system: optical manipulation of both microfluid and microscopic particles", PROCEEDINGS OF THE SPIE - OPTICAL TRAPPING AND OPTICAL MICROMANIPULATION, vol. 5514, October 2004 (2004-10-01), pages 73 - 81, XP002367224 *
CHOU CHIA-FU, TEGENFELDT JONAS O, BAKAJIN OLGICA, CHAN SHIRLEY S, COX EDWARD C, DARNTON NICHOLAS, DUKE THOMAS, AUSTIN ROBERT H: "Electrodeless Dielectrophoresis of Single- and Double-Stranded DNA", BIOPHYSICAL JOURNAL, vol. 83, October 2002 (2002-10-01), pages 2170 - 2179, XP002367222 *
DHOLAKIA: "Interference patterns for advanced optical micromanipulation", PROCEEDINGS OF THE SPIE: INTERFEROMETRY XII, vol. 5531, August 2004 (2004-08-01), pages 1 - 6, XP002367221 *
GASCOYNE PETER R C, VYKOUKAL JODY: "Particle separation by dielectrophoresis", ELECTROPHORESIS, vol. 23, 2002, pages 1973 - 1983, XP002367225 *
MILNE, GRAHAM, MCGLOIN DAVID, TATARKOVA SVETLANA, SIBBETT WILSON, DHOLAKIA KISHAN: "Rectifying transport of a mixture of Brownian particles on an asymmetric periodic optical potential", PROCEEDINGS OF THE SPIE - COMPLEX DYNAMICS, FLUCTUATIONS, CHAOS, AND FRACTALS IN BIOMECHANICAL PHOTONICS, vol. 5330, May 2004 (2004-05-01), pages 112 - 119, XP002367220 *

Also Published As

Publication number Publication date
GB0421166D0 (en) 2004-10-27
WO2006032844A2 (en) 2006-03-30

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