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WO2006028996A3 - Emulsan-alginate microspheres and methods of use thereof - Google Patents

Emulsan-alginate microspheres and methods of use thereof Download PDF

Info

Publication number
WO2006028996A3
WO2006028996A3 PCT/US2005/031372 US2005031372W WO2006028996A3 WO 2006028996 A3 WO2006028996 A3 WO 2006028996A3 US 2005031372 W US2005031372 W US 2005031372W WO 2006028996 A3 WO2006028996 A3 WO 2006028996A3
Authority
WO
WIPO (PCT)
Prior art keywords
emulsan
methods
alginate
compositions
alginate microspheres
Prior art date
Application number
PCT/US2005/031372
Other languages
French (fr)
Other versions
WO2006028996A2 (en
Inventor
David L Kaplan
Guillermo R Castro
Bruce Panilaitis
Original Assignee
Tufts College
David L Kaplan
Guillermo R Castro
Bruce Panilaitis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tufts College, David L Kaplan, Guillermo R Castro, Bruce Panilaitis filed Critical Tufts College
Publication of WO2006028996A2 publication Critical patent/WO2006028996A2/en
Publication of WO2006028996A3 publication Critical patent/WO2006028996A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface

Landscapes

  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

The present invention relates generally to emulsan-alginate compositions and to methods of use. Methods are provided for use of emulsan-alginate compositions as drug delivery vehicles. In addition, methods are provided for use of emulsan-alginate compositions in applications requiring protein adsorption (e.g removal of protein toxins from food products or other products and solutions). The compositions of the invention avoid some of the problems seen in the art with alginate microspheres or particles.
PCT/US2005/031372 2004-09-03 2005-09-02 Emulsan-alginate microspheres and methods of use thereof WO2006028996A2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US60700504P 2004-09-03 2004-09-03
US60/607,005 2004-09-03
US60761104P 2004-09-07 2004-09-07
US60/607,611 2004-09-07
US64380705P 2005-01-14 2005-01-14
US60/643,807 2005-01-14

Publications (2)

Publication Number Publication Date
WO2006028996A2 WO2006028996A2 (en) 2006-03-16
WO2006028996A3 true WO2006028996A3 (en) 2009-05-07

Family

ID=36036885

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/031372 WO2006028996A2 (en) 2004-09-03 2005-09-02 Emulsan-alginate microspheres and methods of use thereof

Country Status (1)

Country Link
WO (1) WO2006028996A2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8886334B2 (en) 2008-10-07 2014-11-11 Mc10, Inc. Systems, methods, and devices using stretchable or flexible electronics for medical applications
US9171794B2 (en) 2012-10-09 2015-10-27 Mc10, Inc. Embedding thin chips in polymer

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* Cited by examiner, † Cited by third party
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EP2650905B1 (en) 2004-06-04 2022-11-09 The Board of Trustees of the University of Illinois Methods and devices for fabricating and assembling printable semiconductor elements
US8389862B2 (en) 2008-10-07 2013-03-05 Mc10, Inc. Extremely stretchable electronics
EP2349440B1 (en) 2008-10-07 2019-08-21 Mc10, Inc. Catheter balloon having stretchable integrated circuitry and sensor array
ES2319158B1 (en) 2008-12-23 2010-01-26 Grifols, S.A COMPOSITION OF BIOCOMPATIBLE ALGINIC ACID MICROPARTICLES FOR THE CONTROLLED RELEASE OF ACTIVE PRINCIPLES BY INTRAVENOUS VIA.
WO2011041727A1 (en) 2009-10-01 2011-04-07 Mc10, Inc. Protective cases with integrated electronics
US9936574B2 (en) 2009-12-16 2018-04-03 The Board Of Trustees Of The University Of Illinois Waterproof stretchable optoelectronics
US10441185B2 (en) 2009-12-16 2019-10-15 The Board Of Trustees Of The University Of Illinois Flexible and stretchable electronic systems for epidermal electronics
US10918298B2 (en) 2009-12-16 2021-02-16 The Board Of Trustees Of The University Of Illinois High-speed, high-resolution electrophysiology in-vivo using conformal electronics
KR101724273B1 (en) 2010-03-17 2017-04-07 더 보드 오브 트러스티즈 오브 더 유니버시티 오브 일리노이 implantable biomedical devices on bioresorbable substrates
US9765934B2 (en) 2011-05-16 2017-09-19 The Board Of Trustees Of The University Of Illinois Thermally managed LED arrays assembled by printing
US9159635B2 (en) 2011-05-27 2015-10-13 Mc10, Inc. Flexible electronic structure
WO2012167096A2 (en) 2011-06-03 2012-12-06 The Board Of Trustees Of The University Of Illinois Conformable actively multiplexed high-density surface electrode array for brain interfacing
GB201120368D0 (en) 2011-11-24 2012-01-04 Sperm Vital As Methods for the preparation of hydrogels
WO2013089867A2 (en) 2011-12-01 2013-06-20 The Board Of Trustees Of The University Of Illinois Transient devices designed to undergo programmable transformations
CN105283122B (en) 2012-03-30 2020-02-18 伊利诺伊大学评议会 Appendable mountable electronics that can conform to surfaces
MX2017015587A (en) 2015-06-01 2018-08-23 Univ Illinois Alternative approach to uv sensing.
MX2017015586A (en) 2015-06-01 2018-08-23 Univ Illinois Miniaturized electronic systems with wireless power and near-field communication capabilities.
US10925543B2 (en) 2015-11-11 2021-02-23 The Board Of Trustees Of The University Of Illinois Bioresorbable silicon electronics for transient implants
KR102100060B1 (en) * 2018-11-08 2020-04-10 가톨릭대학교 산학협력단 Emulsan Nanoparticle for Drug Delivery and Use of the Same

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4690682A (en) * 1983-04-15 1987-09-01 Damon Biotech, Inc. Sustained release
US6214331B1 (en) * 1995-06-06 2001-04-10 C. R. Bard, Inc. Process for the preparation of aqueous dispersions of particles of water-soluble polymers and the particles obtained

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4690682A (en) * 1983-04-15 1987-09-01 Damon Biotech, Inc. Sustained release
US6214331B1 (en) * 1995-06-06 2001-04-10 C. R. Bard, Inc. Process for the preparation of aqueous dispersions of particles of water-soluble polymers and the particles obtained

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CASTRO ET AL.: "Emuslan, a tailorable biopolymer for controlled release.", BIORESOURCE TECHNOLOGY, vol. 99, 2008, pages 4566 - 4571 *
CASTRO ET AL.: "Triggered release of proteins from emulsan-alginate beads.", JOURNAL OF CONTROLLED RELEASE, vol. 109, December 2005 (2005-12-01), pages 149 - 157 *
GUTNICK ET AL.: "Engineering bacterial biopolymers for the biosorption of heavy metals; new products and novel formulations", APPL MICROBIOL BIOTECHNOL, vol. 54, 2000, pages 451 - 460 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8886334B2 (en) 2008-10-07 2014-11-11 Mc10, Inc. Systems, methods, and devices using stretchable or flexible electronics for medical applications
US9171794B2 (en) 2012-10-09 2015-10-27 Mc10, Inc. Embedding thin chips in polymer

Also Published As

Publication number Publication date
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