+

WO2006019429A3 - Procedes d'identification et d'utilisation d'agents accroissant l'inhibition de l'infection au hcf ou la resistance a celle-ci - Google Patents

Procedes d'identification et d'utilisation d'agents accroissant l'inhibition de l'infection au hcf ou la resistance a celle-ci Download PDF

Info

Publication number
WO2006019429A3
WO2006019429A3 PCT/US2005/012648 US2005012648W WO2006019429A3 WO 2006019429 A3 WO2006019429 A3 WO 2006019429A3 US 2005012648 W US2005012648 W US 2005012648W WO 2006019429 A3 WO2006019429 A3 WO 2006019429A3
Authority
WO
WIPO (PCT)
Prior art keywords
resistance
methods
identifying
agents
hcv infection
Prior art date
Application number
PCT/US2005/012648
Other languages
English (en)
Other versions
WO2006019429A2 (fr
Inventor
Hengli Tang
Flossie Wong-Staal
Original Assignee
Immusol Inc
Hengli Tang
Flossie Wong-Staal
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immusol Inc, Hengli Tang, Flossie Wong-Staal filed Critical Immusol Inc
Publication of WO2006019429A2 publication Critical patent/WO2006019429A2/fr
Publication of WO2006019429A3 publication Critical patent/WO2006019429A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/18—Togaviridae; Flaviviridae

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne des procédés d'identification d'agents accroissant l'inhibition d'une infection virale ou la résistance à celle-ci, plus précisément à une infection au HCV (virus de l'hépatite C). L'invention concerne également des procédés et des composants accroissant une telle inhibition ou résistance.
PCT/US2005/012648 2004-04-22 2005-04-15 Procedes d'identification et d'utilisation d'agents accroissant l'inhibition de l'infection au hcf ou la resistance a celle-ci WO2006019429A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56454604P 2004-04-22 2004-04-22
US60/564,546 2004-04-22

Publications (2)

Publication Number Publication Date
WO2006019429A2 WO2006019429A2 (fr) 2006-02-23
WO2006019429A3 true WO2006019429A3 (fr) 2006-08-10

Family

ID=35907830

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/012648 WO2006019429A2 (fr) 2004-04-22 2005-04-15 Procedes d'identification et d'utilisation d'agents accroissant l'inhibition de l'infection au hcf ou la resistance a celle-ci

Country Status (1)

Country Link
WO (1) WO2006019429A2 (fr)

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BHOPALE ET AL.: "Emerging drugs for chronic hepatitis C", HEPATOLOGY RESEARCH, vol. 32, no. 3, July 2005 (2005-07-01), pages 146 - 153, XP004999344 *
KAPADIA ET AL.: "Interference of hepatitis C virus RNA replication by short interfering RNAs", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, USA, vol. 100, no. 4, February 2003 (2003-02-01), pages 2014 - 2018, XP002251050 *
TANG ET AL.: "Novel technologies for studying virus-host interaction and discovering new drug targets for HCV and HIV", CURRENT OPINION IN PHARMACOLOGY, vol. 12, no. 5, October 2002 (2002-10-01), pages 541 - 547, XP003002407 *
TANI ET AL.: "p125 is a novel mammalian Sec23p-interacting protein with structural similarity to phospholipid-modifying proteins", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 274, no. 29, July 1999 (1999-07-01), pages 20505 - 20512, XP002211138 *

Also Published As

Publication number Publication date
WO2006019429A2 (fr) 2006-02-23

Similar Documents

Publication Publication Date Title
WO2007140200A3 (fr) Inhibiteurs de la ns5b du vch à base d'indolobenzazépine fusionnée au cyclopropyle
WO2007140254A3 (fr) Inhibiteurs de ns5b de vhc de type indolobenzapénine fusionnée cyclopropyle
WO2009039246A3 (fr) Procédés de traitement d'une infection par un virus de la famille des flaviviridae, compositions pour traiter une infection par un virus de la famille des flaviviridae, et tests d'identification par criblage des compositions pour traiter une infection par un virus de la famille des flaviviridae
WO2001077091A3 (fr) Inhibiteurs de polymerases ns5b vhc
EA200501689A1 (ru) Соединения в качестве ингибиторов вируса гепатита c
WO2007092888A3 (fr) Inhibiteurs ns5b hcv
WO2007084413A3 (fr) Procedes de traitement de l’hepatite c
WO2008133753A3 (fr) Composés antiviraux
WO2007076034A3 (fr) Composes antiviraux
WO2007081517A8 (fr) Composes anti-viraux
WO2007076035A3 (fr) Composes antiviraux
EA200700243A1 (ru) Способы лечения гепатита с
CR20110153A (es) Inhibidores de la arn polimerasa dependiente del arn del virus de la hepatitis c y composiciones (divisional solicitud 8935)
GEP20104956B (en) Compounds for inhibiting hepatitis c viral replication and use thereof
WO2007001406A3 (fr) Composes macrocycliques contenant un aryle
WO2006086381A3 (fr) Inhibiteurs du virus de l'hepatite c
HRP20041085B1 (hr) Inhibitori hepatitis c virusa
WO2005051980A8 (fr) Inhibiteurs depourvus de liaisons peptidiques de la protease ns3 du virus de l'hepatite c
EA200500584A1 (ru) Нуклеозидные производные для лечения инфекционных заболеваний, вызванных вирусом гепатита c
TW200745035A (en) Cyclopropyl fused indolobenzazepine HCV NS5B inhibitors
AU2003224371A1 (en) Inhibitors of hepatitis c virus rna-dependent rna polymerase, and compositions and treatments using the same
WO2005000308A3 (fr) Procedes d'identification des inhibiteurs de la polymerase vhc-ns5b et utilisations associees
ATE555794T1 (de) Heilmittel gegen hepatitis
WO2005034850A3 (fr) Heterocycles de cycloalkyle destines a traiter le virus de l'hepatite c
EP2392588A3 (fr) Variantes du virus de l'hépatite C

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KM KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SM SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
NENP Non-entry into the national phase

Ref country code: DE

WWW Wipo information: withdrawn in national office

Country of ref document: DE

122 Ep: pct application non-entry in european phase
点击 这是indexloc提供的php浏览器服务，不要输入任何密码和下载