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WO2006018425A3 - Membrane semi-permeable multiphase biocompatible pour biocapteurs - Google Patents

Membrane semi-permeable multiphase biocompatible pour biocapteurs Download PDF

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Publication number
WO2006018425A3
WO2006018425A3 PCT/EP2005/054000 EP2005054000W WO2006018425A3 WO 2006018425 A3 WO2006018425 A3 WO 2006018425A3 EP 2005054000 W EP2005054000 W EP 2005054000W WO 2006018425 A3 WO2006018425 A3 WO 2006018425A3
Authority
WO
WIPO (PCT)
Prior art keywords
membrane
biosensors
multiphase
permeable membrane
biocompatible semi
Prior art date
Application number
PCT/EP2005/054000
Other languages
English (en)
Other versions
WO2006018425A2 (fr
Inventor
Charlotte C Rossmeisl
Mads Christian Sabra
Michael Gerstenberg
Kristian Glejboel
Thomas Buch-Rasmussen
Original Assignee
Novo Nordisk As
Charlotte C Rossmeisl
Mads Christian Sabra
Michael Gerstenberg
Kristian Glejboel
Thomas Buch-Rasmussen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As, Charlotte C Rossmeisl, Mads Christian Sabra, Michael Gerstenberg, Kristian Glejboel, Thomas Buch-Rasmussen filed Critical Novo Nordisk As
Priority to JP2007526455A priority Critical patent/JP2008510154A/ja
Priority to EP05775831A priority patent/EP1784249A2/fr
Publication of WO2006018425A2 publication Critical patent/WO2006018425A2/fr
Publication of WO2006018425A3 publication Critical patent/WO2006018425A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/002—Electrode membranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/411—Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/14—Dynamic membranes
    • B01D69/141—Heterogeneous membranes, e.g. containing dispersed material; Mixed matrix membranes
    • B01D69/1411—Heterogeneous membranes, e.g. containing dispersed material; Mixed matrix membranes containing dispersed material in a continuous matrix
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
    • B01D71/06—Organic material
    • B01D71/70—Polymers having silicon in the main chain, with or without sulfur, nitrogen, oxygen or carbon only
    • B01D71/701—Polydimethylsiloxane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
    • B01D71/06—Organic material
    • B01D71/54—Polyureas; Polyurethanes

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Vascular Medicine (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)

Abstract

La présente invention concerne une membrane semi-perméable bi-phase biocompatible pour biocapteurs, et plus particulièrement une membrane homogène destiné à la détection in-vivo du glucose par une enzyme. Cette membrane est faite d'une phase hydrophile continue de polyuréthane gonflant par l'eau dans laquelle sont dispersées des particules discrètes de polydiméthyle-siloxane. L'invention concerne en outre une membrane présentant de bonne propriétés pour une utilisation comme membrane extérieure d'un biocapteur de détermination continue de la glycémie in-vivo, et que l'on peut élaborer en pulvérisant une solution de polymère dans un grand nombre d'opérations de pulvérisation, par exemple, plus de 20 opérations.
PCT/EP2005/054000 2004-08-16 2005-08-15 Membrane semi-permeable multiphase biocompatible pour biocapteurs WO2006018425A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2007526455A JP2008510154A (ja) 2004-08-16 2005-08-15 バイオセンサーのための多相系生物適合型の半透過性膜
EP05775831A EP1784249A2 (fr) 2004-08-16 2005-08-15 Membrane semi-permeable multiphase biocompatible pour biocapteurs

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DKPA200401234 2004-08-16
DKPA200401234 2004-08-16
DKPA200401235 2004-08-16
DKPA200401235 2004-08-16

Publications (2)

Publication Number Publication Date
WO2006018425A2 WO2006018425A2 (fr) 2006-02-23
WO2006018425A3 true WO2006018425A3 (fr) 2006-06-08

Family

ID=35276209

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2005/054000 WO2006018425A2 (fr) 2004-08-16 2005-08-15 Membrane semi-permeable multiphase biocompatible pour biocapteurs

Country Status (3)

Country Link
EP (1) EP1784249A2 (fr)
JP (1) JP2008510154A (fr)
WO (1) WO2006018425A2 (fr)

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US7455663B2 (en) 2006-08-23 2008-11-25 Medtronic Minimed, Inc. Infusion medium delivery system, device and method with needle inserter and needle inserter device and method
US7569050B2 (en) 2005-05-06 2009-08-04 Medtronic Minimed, Inc. Infusion device and method with drive device in infusion device and method with drive device in separable durable housing portion
US7613491B2 (en) 2002-05-22 2009-11-03 Dexcom, Inc. Silicone based membranes for use in implantable glucose sensors
US7736344B2 (en) 2006-08-23 2010-06-15 Medtronic Minimed, Inc. Infusion medium delivery device and method with drive device for driving plunger in reservoir
US7794434B2 (en) 2006-08-23 2010-09-14 Medtronic Minimed, Inc. Systems and methods allowing for reservoir filling and infusion medium delivery
US7811262B2 (en) 2006-08-23 2010-10-12 Medtronic Minimed, Inc. Systems and methods allowing for reservoir filling and infusion medium delivery
US7828764B2 (en) 2006-08-23 2010-11-09 Medtronic Minimed, Inc. Systems and methods allowing for reservoir filling and infusion medium delivery
US7959715B2 (en) 2007-04-30 2011-06-14 Medtronic Minimed, Inc. Systems and methods allowing for reservoir air bubble management
US7963954B2 (en) 2007-04-30 2011-06-21 Medtronic Minimed, Inc. Automated filling systems and methods
US8025658B2 (en) 2007-04-30 2011-09-27 Medtronic Minimed, Inc. Adhesive patch systems and methods
US8137314B2 (en) 2006-08-23 2012-03-20 Medtronic Minimed, Inc. Infusion medium delivery device and method with compressible or curved reservoir or conduit
US8187228B2 (en) 2006-08-23 2012-05-29 Medtronic Minimed, Inc. Infusion pumps and methods and delivery devices and methods with same
US8277415B2 (en) 2006-08-23 2012-10-02 Medtronic Minimed, Inc. Infusion medium delivery device and method with drive device for driving plunger in reservoir
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US8434528B2 (en) 2007-04-30 2013-05-07 Medtronic Minimed, Inc. Systems and methods for reservoir filling
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US8512288B2 (en) 2006-08-23 2013-08-20 Medtronic Minimed, Inc. Infusion medium delivery device and method with drive device for driving plunger in reservoir
US8597243B2 (en) 2007-04-30 2013-12-03 Medtronic Minimed, Inc. Systems and methods allowing for reservoir air bubble management
US8613725B2 (en) 2007-04-30 2013-12-24 Medtronic Minimed, Inc. Reservoir systems and methods
US8840586B2 (en) 2006-08-23 2014-09-23 Medtronic Minimed, Inc. Systems and methods allowing for reservoir filling and infusion medium delivery
US8909314B2 (en) 2003-07-25 2014-12-09 Dexcom, Inc. Oxygen enhancing membrane systems for implantable devices
US8954128B2 (en) 2008-03-28 2015-02-10 Dexcom, Inc. Polymer membranes for continuous analyte sensors
US8968198B2 (en) 2006-02-22 2015-03-03 Dexcom, Inc. Analyte sensor
US8989833B2 (en) 2004-07-13 2015-03-24 Dexcom, Inc. Transcutaneous analyte sensor
US9131885B2 (en) 2009-07-02 2015-09-15 Dexcom, Inc. Analyte sensors and methods of manufacturing same
US9173606B2 (en) 2008-03-28 2015-11-03 Dexcom, Inc. Polymer membranes for continuous analyte sensors
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
US9328371B2 (en) 2001-07-27 2016-05-03 Dexcom, Inc. Sensor head for use with implantable devices
US9339223B2 (en) 1997-03-04 2016-05-17 Dexcom, Inc. Device and method for determining analyte levels
US9339222B2 (en) 2008-09-19 2016-05-17 Dexcom, Inc. Particle-containing membrane and particulate electrode for analyte sensors
US9351677B2 (en) 2009-07-02 2016-05-31 Dexcom, Inc. Analyte sensor with increased reference capacity
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US9439589B2 (en) 1997-03-04 2016-09-13 Dexcom, Inc. Device and method for determining analyte levels

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US9763609B2 (en) 2003-07-25 2017-09-19 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
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US8744546B2 (en) 2005-05-05 2014-06-03 Dexcom, Inc. Cellulosic-based resistance domain for an analyte sensor
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US11364335B2 (en) 2006-02-09 2022-06-21 Deka Products Limited Partnership Apparatus, system and method for fluid delivery
US11497846B2 (en) 2006-02-09 2022-11-15 Deka Products Limited Partnership Patch-sized fluid delivery systems and methods
US12274857B2 (en) 2006-02-09 2025-04-15 Deka Products Limited Partnership Method and system for shape-memory alloy wire control
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US8323250B2 (en) 2007-04-30 2012-12-04 Medtronic Minimed, Inc. Adhesive patch systems and methods
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US8900188B2 (en) 2007-12-31 2014-12-02 Deka Products Limited Partnership Split ring resonator antenna adapted for use in wirelessly controlled medical device
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US9339223B2 (en) 1997-03-04 2016-05-17 Dexcom, Inc. Device and method for determining analyte levels
US9439589B2 (en) 1997-03-04 2016-09-13 Dexcom, Inc. Device and method for determining analyte levels
US9328371B2 (en) 2001-07-27 2016-05-03 Dexcom, Inc. Sensor head for use with implantable devices
US9549693B2 (en) 2002-05-22 2017-01-24 Dexcom, Inc. Silicone based membranes for use in implantable glucose sensors
US7613491B2 (en) 2002-05-22 2009-11-03 Dexcom, Inc. Silicone based membranes for use in implantable glucose sensors
US9597027B2 (en) 2003-07-25 2017-03-21 Dexcom, Inc. Oxygen enhancing membrane systems for implantable devices
US8909314B2 (en) 2003-07-25 2014-12-09 Dexcom, Inc. Oxygen enhancing membrane systems for implantable devices
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
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US7569050B2 (en) 2005-05-06 2009-08-04 Medtronic Minimed, Inc. Infusion device and method with drive device in infusion device and method with drive device in separable durable housing portion
US9233203B2 (en) 2005-05-06 2016-01-12 Medtronic Minimed, Inc. Medical needles for damping motion
US9180248B2 (en) 2005-05-06 2015-11-10 Medtronic Minimed, Inc. Infusion device with base portion and durable portion
US7935085B2 (en) 2005-05-06 2011-05-03 Medtronic Minimed, Inc. Infusion device and method with disposable portion
US7955305B2 (en) 2005-05-06 2011-06-07 Medtronic Minimed, Inc. Needle inserter and method for infusion device
US8529553B2 (en) 2005-08-23 2013-09-10 Medtronic Minimed, Inc. Infusion medium delivery device and method with drive device for driving plunger in reservoir
US8545445B2 (en) 2006-02-09 2013-10-01 Deka Products Limited Partnership Patch-sized fluid delivery systems and methods
US8303574B2 (en) 2006-02-09 2012-11-06 Deka Products Limited Partnership Adhesive and peripheral systems and methods for medical devices
US12036387B2 (en) 2006-02-09 2024-07-16 Deka Products Limited Partnership Device to determine volume of fluid dispensed
US8998850B2 (en) 2006-02-09 2015-04-07 Deka Products Limited Partnership Adhesive and peripheral systems and methods for medical devices
US9259531B2 (en) 2006-02-09 2016-02-16 Deka Products Limited Partnership Adhesive and peripheral systems and methods for medical devices
US8585377B2 (en) 2006-02-09 2013-11-19 Deka Products Limited Partnership Pumping fluid delivery systems and methods using force application assembly
US8414522B2 (en) 2006-02-09 2013-04-09 Deka Products Limited Partnership Fluid delivery systems and methods
US8968198B2 (en) 2006-02-22 2015-03-03 Dexcom, Inc. Analyte sensor
US7744589B2 (en) 2006-08-23 2010-06-29 Medtronic Minimed, Inc. Infusion medium delivery device and method with drive device for driving plunger in reservoir
US7455663B2 (en) 2006-08-23 2008-11-25 Medtronic Minimed, Inc. Infusion medium delivery system, device and method with needle inserter and needle inserter device and method
US8226615B2 (en) 2006-08-23 2012-07-24 Medtronic Minimed, Inc. Infusion medium delivery system, device and method with needle inserter and needle inserter device and method
US8202250B2 (en) 2006-08-23 2012-06-19 Medtronic Minimed, Inc. Infusion pumps and methods and delivery devices and methods with same
US7736338B2 (en) 2006-08-23 2010-06-15 Medtronic Minimed, Inc. Infusion medium delivery system, device and method with needle inserter and needle inserter device and method
US7736344B2 (en) 2006-08-23 2010-06-15 Medtronic Minimed, Inc. Infusion medium delivery device and method with drive device for driving plunger in reservoir
US8444607B2 (en) 2006-08-23 2013-05-21 Medtronic Minimed, Inc. Infusion medium delivery device and method with drive device for driving plunger in reservoir
US7905868B2 (en) 2006-08-23 2011-03-15 Medtronic Minimed, Inc. Infusion medium delivery device and method with drive device for driving plunger in reservoir
US8137314B2 (en) 2006-08-23 2012-03-20 Medtronic Minimed, Inc. Infusion medium delivery device and method with compressible or curved reservoir or conduit
US8512288B2 (en) 2006-08-23 2013-08-20 Medtronic Minimed, Inc. Infusion medium delivery device and method with drive device for driving plunger in reservoir
US7789857B2 (en) 2006-08-23 2010-09-07 Medtronic Minimed, Inc. Infusion medium delivery system, device and method with needle inserter and needle inserter device and method
US8277415B2 (en) 2006-08-23 2012-10-02 Medtronic Minimed, Inc. Infusion medium delivery device and method with drive device for driving plunger in reservoir
US8187228B2 (en) 2006-08-23 2012-05-29 Medtronic Minimed, Inc. Infusion pumps and methods and delivery devices and methods with same
US8172804B2 (en) 2006-08-23 2012-05-08 Medtronic Minimed, Inc. Infusion medium delivery system, device and method with needle inserter and needle inserter device and method
US7794434B2 (en) 2006-08-23 2010-09-14 Medtronic Minimed, Inc. Systems and methods allowing for reservoir filling and infusion medium delivery
US7811262B2 (en) 2006-08-23 2010-10-12 Medtronic Minimed, Inc. Systems and methods allowing for reservoir filling and infusion medium delivery
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