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WO2006004577A3 - Lubricant for the ocular surface - Google Patents

Lubricant for the ocular surface Download PDF

Info

Publication number
WO2006004577A3
WO2006004577A3 PCT/US2005/006737 US2005006737W WO2006004577A3 WO 2006004577 A3 WO2006004577 A3 WO 2006004577A3 US 2005006737 W US2005006737 W US 2005006737W WO 2006004577 A3 WO2006004577 A3 WO 2006004577A3
Authority
WO
WIPO (PCT)
Prior art keywords
eyedrop
well
lubricant
ocular surface
jojoba wax
Prior art date
Application number
PCT/US2005/006737
Other languages
French (fr)
Other versions
WO2006004577A2 (en
Inventor
Steven Maskin
Original Assignee
Melbj Holdings Llc
Steven Maskin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Melbj Holdings Llc, Steven Maskin filed Critical Melbj Holdings Llc
Priority to EP05794290A priority Critical patent/EP1727565A2/en
Priority to JP2007502857A priority patent/JP2007528897A/en
Priority to CA002559503A priority patent/CA2559503A1/en
Priority to AU2005260090A priority patent/AU2005260090B2/en
Publication of WO2006004577A2 publication Critical patent/WO2006004577A2/en
Publication of WO2006004577A3 publication Critical patent/WO2006004577A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Reproductive Health (AREA)
  • Oncology (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
  • Botany (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pulmonology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Preparation (AREA)
  • Eyeglasses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

A formulation has been developed for treatment of the symptoms of dry eye which incorporates the natural product jojoba wax, or components thereof, to enhance the spreading of the artificial tear and eyedrop as well as stabilize the eyedrop. The improved performance of the jojoba wax supplemented tear relieves irritation and discomfort as well as sharpens the blurred vision.
PCT/US2005/006737 2004-03-12 2005-03-01 Lubricant for the ocular surface WO2006004577A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP05794290A EP1727565A2 (en) 2004-03-12 2005-03-01 Lubricant for the ocular surface
JP2007502857A JP2007528897A (en) 2004-03-12 2005-03-01 Lubricant for ocular surface
CA002559503A CA2559503A1 (en) 2004-03-12 2005-03-01 Lubricant for the ocular surface
AU2005260090A AU2005260090B2 (en) 2004-03-12 2005-03-01 Lubricant for the ocular surface

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US55247704P 2004-03-12 2004-03-12
US60/552,477 2004-03-12
US56268304P 2004-04-15 2004-04-15
US60/562,683 2004-04-15

Publications (2)

Publication Number Publication Date
WO2006004577A2 WO2006004577A2 (en) 2006-01-12
WO2006004577A3 true WO2006004577A3 (en) 2006-07-20

Family

ID=35311617

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/006737 WO2006004577A2 (en) 2004-03-12 2005-03-01 Lubricant for the ocular surface

Country Status (5)

Country Link
EP (1) EP1727565A2 (en)
JP (1) JP2007528897A (en)
AU (1) AU2005260090B2 (en)
CA (1) CA2559503A1 (en)
WO (1) WO2006004577A2 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2451452A (en) * 2007-07-30 2009-02-04 Donald Henry Yates A lubricant formulation
US20130023575A1 (en) * 2011-07-22 2013-01-24 Kamran Hosseini Compositions and methods for the treatment of ocular surface allergies
ITFI20120044A1 (en) * 2012-03-01 2013-09-02 Biodue Spa FORMULATION FOR OPHTHALMIC USE INCLUDING JOJOBA OIL.
JP5989365B2 (en) * 2012-03-19 2016-09-07 ロート製薬株式会社 Contact lens ophthalmic composition
KR20150046300A (en) * 2012-08-31 2015-04-29 보오슈 앤드 롬 인코포레이팃드 Ophthalmic compositions with omega-3 fatty acids
JP6290929B2 (en) * 2013-01-24 2018-03-07 ボシュ・アンド・ロム・インコーポレイテッドBausch & Lomb Incorporated Ophthalmic composition having an alkoxylated natural wax
WO2014208709A1 (en) 2013-06-28 2014-12-31 学校法人 慶應義塾 Agent for treating meibomian gland dysfunction
EP3261620B1 (en) * 2015-02-24 2022-11-09 The Board of Trustees of the University of Illinois Methods and compositions for treating dry eye disease and other eye disorders
CN105749360B (en) * 2016-03-28 2019-06-18 赛克赛斯生物科技股份有限公司 A kind of composition and the preparation method and application thereof for protecting cornea
EP3500344A4 (en) * 2016-08-19 2020-08-05 Akrivista, LLC Methods of diagnosing and treating dry eye syndrome and compositions for treating a human eye
CN110996904A (en) 2017-05-19 2020-04-10 奥古根有限公司 Ophthalmic compositions and methods of use
KR20200037230A (en) * 2017-06-30 2020-04-08 제니비젼 인크. Formulations for hair growth
EP3668474A4 (en) 2017-08-18 2021-05-26 Akrivista, LLC METHODS OF DIAGNOSIS AND TREATMENT OF DRY EYE SYNDROME AND COMPOSITIONS FOR TREATMENT OF A HUMAN EYE
NO345574B1 (en) * 2018-06-19 2021-04-26 Epax Norway As Composition for treatment of dry eye disease and meibomianitis
EP3893842A1 (en) * 2018-12-10 2021-10-20 Eternatear, Inc. Ophthalmic formulations providing durable ocular lubrication
KR102221500B1 (en) * 2019-06-10 2021-03-04 인제대학교 산학협력단 Method for manufacturing contact lens comprising beta-carotene for blocking blue lights
CN115475248A (en) * 2021-06-16 2022-12-16 云南拜奥泰克生物技术有限责任公司 Novel medicinal triglyceride solvent and application thereof
US11679078B1 (en) 2022-03-08 2023-06-20 EternaTear, Inc. Ophthalmic formulations and related methods
US11471475B1 (en) 2022-03-08 2022-10-18 Ralph P. Stone Ophthalmic suspension vehicles and related methods for pharmaceutical ingredient delivery
CN119345085A (en) * 2024-10-28 2025-01-24 浙江睛姿化妆品有限公司 Natural plant eyeliner liquid containing eyelash growth ingredients and preparation method thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0535545A1 (en) * 1991-10-02 1993-04-07 Ocular Research Of Boston Inc. Artificial tears containing oil and wax
EP0875244A2 (en) * 1997-05-02 1998-11-04 Ciba SC Holding AG Cosmetically accceptable microstructured compositions
WO2002051379A2 (en) * 2000-12-23 2002-07-04 Impetus Ag Thixotropic nasal spray
US20030008022A1 (en) * 2001-07-07 2003-01-09 Mogy Nabil Sadek El Medical effect of jojoba oil
WO2003049674A2 (en) * 2001-11-07 2003-06-19 Purcell Jojoba International, Inc. Method for treatment of enveloped viruses using jojoba oil esters

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2495187A1 (en) * 1980-12-02 1982-06-04 Siderurgie Fse Inst Rech PROCESS FOR PRODUCING METALLURGICAL CONTAINER FUND

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0535545A1 (en) * 1991-10-02 1993-04-07 Ocular Research Of Boston Inc. Artificial tears containing oil and wax
EP0875244A2 (en) * 1997-05-02 1998-11-04 Ciba SC Holding AG Cosmetically accceptable microstructured compositions
WO2002051379A2 (en) * 2000-12-23 2002-07-04 Impetus Ag Thixotropic nasal spray
US20030008022A1 (en) * 2001-07-07 2003-01-09 Mogy Nabil Sadek El Medical effect of jojoba oil
WO2003049674A2 (en) * 2001-11-07 2003-06-19 Purcell Jojoba International, Inc. Method for treatment of enveloped viruses using jojoba oil esters

Also Published As

Publication number Publication date
JP2007528897A (en) 2007-10-18
WO2006004577A2 (en) 2006-01-12
CA2559503A1 (en) 2006-01-12
AU2005260090B2 (en) 2008-06-05
EP1727565A2 (en) 2006-12-06
AU2005260090A1 (en) 2006-01-12

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