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WO2006066466A1 - A filling member for fixing and fusing together adjacent cervical vertebrae - Google Patents

A filling member for fixing and fusing together adjacent cervical vertebrae Download PDF

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Publication number
WO2006066466A1
WO2006066466A1 PCT/CN2005/000003 CN2005000003W WO2006066466A1 WO 2006066466 A1 WO2006066466 A1 WO 2006066466A1 CN 2005000003 W CN2005000003 W CN 2005000003W WO 2006066466 A1 WO2006066466 A1 WO 2006066466A1
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WO
WIPO (PCT)
Prior art keywords
filling member
fixing
fusion
cervical
cervical vertebrae
Prior art date
Application number
PCT/CN2005/000003
Other languages
French (fr)
Chinese (zh)
Inventor
Shouheng Yang
Tianjing Zhu
Original Assignee
Shouheng Yang
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Publication date
Application filed by Shouheng Yang filed Critical Shouheng Yang
Publication of WO2006066466A1 publication Critical patent/WO2006066466A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/4455—Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/30772—Apertures or holes, e.g. of circular cross section
    • A61F2002/30784—Plurality of holes
    • A61F2002/30789—Plurality of holes perpendicular with respect to each other
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/30904—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves serrated profile, i.e. saw-toothed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00359—Bone or bony tissue

Definitions

  • the invention belongs to the technical field of medical bone tools.
  • Orthopedic medical practice after experiencing cervical disc removal of spinal instability, degenerative cervical disc disease or spinal instability, or ⁇ 0 ⁇ ⁇ spondylolisthesis and other symptoms, often taken placed between vertebral bodies made of metal material
  • the internal fixation bracket - Cage for treatment For example, internal fixation products such as TFC and BAK have been replaced by the recently popular SynCage C and Solis Cervical Cage because of the small bearing surface and the complications such as sinking and slippage after filling the bone.
  • these internal fixations are foreign bodies of a metal frame structure, and it is not necessary to fill the bone graft in the frame.
  • the polymer Solis although degradable, is still considered to be less than ideal.
  • the technical solution of the present invention is a cervical interbody fusion fusion pad, see FIG. 1-2, having a columnar body 4 with a central hole 2, which is made of fresh and healthy mammalian bones, and is freshly drawn.
  • the body 4 of the healthy mammal bone has a circular cross section, and the upper and lower bottom surfaces of the cylindrical body 4 are convexly convex and distributed with convex teeth 1 respectively, and the cylindrical surface of the body 4 has a through hole 3 radially.
  • the cervical interbody fusion fusion pad of the present invention is obtained by processing fresh and healthy mammalian bone into a cylindrical body having a cylindrical shape and a bottom and bottom body as described above.
  • the faces are convexly curved and distributed with convex teeth 1 (see Fig. 1).
  • more than one of the necessary mechanical processing in the car, clamp, planing and milling can obtain the above-mentioned cervical interbody fusion fusion pad products.
  • the finished product is sterilized and used.
  • the cervical interbody fusion fusion pad has greater mechanical strength and can be used for support fixation and fusion between the anterior cervical vertebrae.
  • the fusion pad made of bone material has the characteristics of non-toxic, non-carcinogenic and non-allergic reaction, and has good compatibility with human tissues, and can slowly absorb and fuse. It is very convenient to install with special tools. It is an ideal C3 ⁇ C7 interbody fusion cage.
  • the finished product of the present invention When the finished product of the present invention is put into medical use, the following manner can be followed. After the disc is removed, the vertebral body cartilage surface is cleaned, and a special pusher is inserted into the cervical vertebrae interbody fusion pad with a through hole 3 and a central hole 2, and the pad is fixed by screws to feed the pad into the vertebral body space, pay attention to the position. Properly placed, the upper and lower arcuate faces and convex teeth of the pad can make the pad and the vertebral body end plate in close contact, and then unscrew the screw to exit the pusher, so that the autogenous bone grows into the through hole 3 on the pad later. Center hole 2 to facilitate bone fusion.
  • a cervical interbody fusion fusion pad comprising the same and heterogeneous bones should fall within the scope of the present invention.
  • the invention adopts bone tissue as a material, has no immunogenicity, has high compressive strength, and can fully bear the weight of the head, and is particularly suitable for the support fixation and fusion between the anterior cervical vertebrae.
  • the invention is convenient to take materials, safe and reliable in quality, and easy to install and apply.
  • the replacement of metallic materials with biological materials is in line with the physiological needs of human body.
  • the above-mentioned body 4 of the present invention may also have a hexagonal cross section as shown in FIG.
  • the shape of the triangle, as shown in Fig. 4, or the shape of an ellipse as shown in Fig. 5, has the same effect.
  • the present invention is based on fresh and healthy mammalian bones, including bovine bone, pig bone, and other mammalian bones, i.e., xenogeneic and homogenous bones.
  • FIG. 1 is a schematic view showing the structure of a cervical intervertebral fusion device.
  • Figure 2 is a cross-sectional view taken along line A-A of Figure 1.
  • Example 1 This example uses bovine bone tissue as a material, and is made of ⁇ 2 ( ⁇ 6 ⁇ cylindrical body 4, central hole diameter ⁇ 6 ⁇ . The upper and lower bottom surfaces are respectively milled into a convex curved surface, A convex tooth 1 is uniformly arranged on the convex arc surface, and a through hole 3 is opened radially on the cylindrical surface of the body 4, and the aperture is ⁇ 1 ⁇ .
  • Example 2 In this example, a porcine bone skeleton was used as a material, and a cylindrical body 4 of 18 mm ⁇ 5 mm size was fabricated by a car, and the central hole diameter was ⁇ 4 ⁇ .
  • the upper and lower bottom surfaces are respectively milled into a convex curved surface, and the convex teeth 1 are uniformly arranged on the convex curved surface, and then a through hole 3 is radially opened on the cylindrical surface of the body 4, and the aperture is ⁇ 1.4 , and the body 4 is made into a hexagonal cylinder.
  • the cervical vertebra interbody fusion fusion pad of the present invention thus constituted has been proved to have a good overall effect, reliable quality, safety and practicability, and remarkable curative effect.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)

Abstract

A filling member for fixing and fusing together adjacent cervical vertebrae is disclosed. The filling member has a cylinder-shaped body (4) with a central aperture (2) . The upper and lower surfaces of the cylinder-shaped body (4) are arced and are provided with a plurality of teeth (1) . The lateral side of the cylinder-shaped body (4) has a radial throughhole (3) . The cylinder­shaped body (4) is made of mammal bones.

Description

颈椎椎体间固定融合垫具  Cervical interbody fusion fusion pad
技术领域 Technical field
本发明属于医疗用接骨器具技术领域。  The invention belongs to the technical field of medical bone tools.
背景技术 Background technique
骨科医疗实践中， 遇到摘除颈椎间盘突出后出现的脊柱不稳定， 或退行性颈椎间盘病变脊柱不稳定， 或 Ι0·^脊柱滑脱等症状， 往往 采取在椎体间放置用金属材料制成的内固定支架 -Cage 进行治疗处 理。 而如 TFC、 BAK等内固定物， 因承载面小， 填充接骨后会引起 下沉与滑脱等并发症，故己被最近流行的 SynCage C和 Solis Cervical Cage 所代替。 然而， 不论前者还是后者， 这些内固定物均为金属框 架结构的异物，不可不在框架内进行填充植骨。而高分子聚合物 Solis 虽然能降解， 但是仍然被认为不够理想。 Orthopedic medical practice, after experiencing cervical disc removal of spinal instability, degenerative cervical disc disease or spinal instability, or Ι 0 · ^ spondylolisthesis and other symptoms, often taken placed between vertebral bodies made of metal material The internal fixation bracket - Cage for treatment. For example, internal fixation products such as TFC and BAK have been replaced by the recently popular SynCage C and Solis Cervical Cage because of the small bearing surface and the complications such as sinking and slippage after filling the bone. However, regardless of the former or the latter, these internal fixations are foreign bodies of a metal frame structure, and it is not necessary to fill the bone graft in the frame. The polymer Solis, although degradable, is still considered to be less than ideal.
发明内容 Summary of the invention
本发明的目的，就是要提供一种既可作为颈椎椎体间的支撑固定 物， 又可作为椎体间植骨的填充物的固定融合器。  SUMMARY OF THE INVENTION It is an object of the present invention to provide a fixation cage that acts both as a support for the cervical vertebral body and as a filler for interbody fusion.
本发明的技术解决方案是， 一种颈椎椎体间固定融合垫具， 参见 图 1-2， 具有带中心孔 2的柱状本体 4， 所述本体 4取材新鲜健康的 哺乳动物骨骼制作，取材新鲜健康的哺乳动物骨骼制作的本体 4截面 呈圆形，圆柱形的本体 4上、下底面分别呈弧面外凸并分布有凸齿 1， 本体 4之柱面上径向开有通孔 3。  The technical solution of the present invention is a cervical interbody fusion fusion pad, see FIG. 1-2, having a columnar body 4 with a central hole 2, which is made of fresh and healthy mammalian bones, and is freshly drawn. The body 4 of the healthy mammal bone has a circular cross section, and the upper and lower bottom surfaces of the cylindrical body 4 are convexly convex and distributed with convex teeth 1 respectively, and the cylindrical surface of the body 4 has a through hole 3 radially.
本发明的这种颈椎椎体间固定融合垫具取材新鲜健康的哺乳动 物骨骼机械加工成如上述其本体呈圆柱形， 圆柱形的本体 4上、下底 面分别呈弧面外凸并分布有凸齿 1， （见图 1 )。 按图 1-2所示规格进 行车、钳、 刨、 铣中一种以上必要的机械加工即可获得上述颈椎椎体 间固定融合垫具成品。成品经灭菌处理后备用。本颈椎椎体间固定融 合垫具具有较大的机械强度，可用于颈椎前路椎体间的支撑固定和融 合。用骨骼材料制成的本融合垫具接骨器具有无毒、无致癌性与无过 敏反应的特点， 与人体组织相容性良好， 可缓慢地吸收融合。 如使用 专用工具进行安装将十分方便， 是一种理想的 C3〜C7椎体间固定融 合器 The cervical interbody fusion fusion pad of the present invention is obtained by processing fresh and healthy mammalian bone into a cylindrical body having a cylindrical shape and a bottom and bottom body as described above. The faces are convexly curved and distributed with convex teeth 1 (see Fig. 1). According to the specifications shown in Figure 1-2, more than one of the necessary mechanical processing in the car, clamp, planing and milling can obtain the above-mentioned cervical interbody fusion fusion pad products. The finished product is sterilized and used. The cervical interbody fusion fusion pad has greater mechanical strength and can be used for support fixation and fusion between the anterior cervical vertebrae. The fusion pad made of bone material has the characteristics of non-toxic, non-carcinogenic and non-allergic reaction, and has good compatibility with human tissues, and can slowly absorb and fuse. It is very convenient to install with special tools. It is an ideal C3~C7 interbody fusion cage.
本发明的成品投入医疗使用时， 可遵循下述方式。将椎间盘摘除 后， 清净椎体软骨面， 用专用推进器伸入颈椎椎体间固定融合垫具通 孔 3和中心孔 2， 以螺杆固定垫具， 将垫具送入椎体间隙， 注意位置 摆放适当，垫具上、下的弧状面和凸齿可使垫具和椎体终板紧密接触， 然后旋开螺杆退出推进器，以让自体骨日后长入垫具上的通孔 3和中 心孔 2， 以利于骨的融合。  When the finished product of the present invention is put into medical use, the following manner can be followed. After the disc is removed, the vertebral body cartilage surface is cleaned, and a special pusher is inserted into the cervical vertebrae interbody fusion pad with a through hole 3 and a central hole 2, and the pad is fixed by screws to feed the pad into the vertebral body space, pay attention to the position. Properly placed, the upper and lower arcuate faces and convex teeth of the pad can make the pad and the vertebral body end plate in close contact, and then unscrew the screw to exit the pusher, so that the autogenous bone grows into the through hole 3 on the pad later. Center hole 2 to facilitate bone fusion.
应该指出的是，包括同种和异种骨骼加工成的颈椎椎体间固定融 合垫具都应落在本发明的保护范围之内。  It should be noted that a cervical interbody fusion fusion pad comprising the same and heterogeneous bones should fall within the scope of the present invention.
本发明采用骨骼组织作材料， 无免疫抗原性， 其抗压强度大， 完 全可承受头部重量，尤其适合于颈椎前路椎体间的支撑固定和融合需 要。  The invention adopts bone tissue as a material, has no immunogenicity, has high compressive strength, and can fully bear the weight of the head, and is particularly suitable for the support fixation and fusion between the anterior cervical vertebrae.
本发明取材方便， 质量安全可靠， 易于安装应用。 以生物材料取 代金属材料， 符合人体生理需要。  The invention is convenient to take materials, safe and reliable in quality, and easy to install and apply. The replacement of metallic materials with biological materials is in line with the physiological needs of human body.
本发明的上述本体 4其截面也可以如图 3所示呈六边形这样的多 边形， 或如图 4所示呈矩形亦或如图 5所示呈椭圆形， 效果一致。 本发明取材新鲜健康的哺乳动物骨骼， 包括牛骨、猪骨和其它哺 乳动物骨骼， 即异种和同种的骨骼制成。 The above-mentioned body 4 of the present invention may also have a hexagonal cross section as shown in FIG. The shape of the triangle, as shown in Fig. 4, or the shape of an ellipse as shown in Fig. 5, has the same effect. The present invention is based on fresh and healthy mammalian bones, including bovine bone, pig bone, and other mammalian bones, i.e., xenogeneic and homogenous bones.
附图说明 DRAWINGS
图 1为本发明颈椎椎体间固定融合垫具的结构示意图。  1 is a schematic view showing the structure of a cervical intervertebral fusion device.
图 2是图 1中 A-A向剖面图。  Figure 2 is a cross-sectional view taken along line A-A of Figure 1.
以上图 1-2中， 1一凸齿  In Figure 1-2 above, 1 convex tooth
2—中心孔  2—center hole
3—通孔  3—through hole
4一本体  4 ontology
具体实施方式 detailed description
实施例 1:本例采用牛骨骨骼组织作材料，经车制成 Φ2( πιΧ6匪 规格的圆柱形本体 4， 中心孔孔径 Φ6ίηιιι。 将上、 下底面分别铣制加 工成外凸的弧面， 外凸的弧面上铣制出排列均匀的凸齿 1， 再在本体 4之柱面上径向开一通孔 3， 孔径 Φ1πιπι。  Example 1: This example uses bovine bone tissue as a material, and is made of Φ2 (ππΧ6匪 cylindrical body 4, central hole diameter Φ6ίηιιι. The upper and lower bottom surfaces are respectively milled into a convex curved surface, A convex tooth 1 is uniformly arranged on the convex arc surface, and a through hole 3 is opened radially on the cylindrical surface of the body 4, and the aperture is Φ1πιπι.
实施例 2:本例采用猪骨骨骼组织作材料，经车制成 18mmX5mm 规格的圆柱形本体 4， 中心孔孔径 Φ4ΙΏΙΙΙ。 将上、 下底面分别铣成外 凸的弧面， 外凸的弧面上铣制出排列均匀的凸齿 1， 再在本体 4之柱 面上径向开一通孔 3， 孔径 Φ1.4酬， 并将本体 4刨制成六边形柱体。  Example 2: In this example, a porcine bone skeleton was used as a material, and a cylindrical body 4 of 18 mm×5 mm size was fabricated by a car, and the central hole diameter was Φ4ΙΏΙΙΙ. The upper and lower bottom surfaces are respectively milled into a convex curved surface, and the convex teeth 1 are uniformly arranged on the convex curved surface, and then a through hole 3 is radially opened on the cylindrical surface of the body 4, and the aperture is Φ1.4 , and the body 4 is made into a hexagonal cylinder.
由此构成的本发明的颈椎椎体间固定融合垫具经试制试用被证 明整体效果良好， 质量可靠， 安全实用， 疗效显著。  The cervical vertebra interbody fusion fusion pad of the present invention thus constituted has been proved to have a good overall effect, reliable quality, safety and practicability, and remarkable curative effect.

Claims

权利 要 求 Rights request
1、 一种颈椎椎体间固定融合垫具， 具有带中心孔（2 ) 的柱状本 体 （4)， 其特征在于， 所述本体 （4) 取材新鲜健康的哺乳动物骨骼 制作， 取材新鲜健康的哺乳动物骨骼制作的本体 （4) 截面呈圆形， 圆柱形的本体 （4 ) 上、 下底面分别呈弧面外凸并分布有凸齿 （1 )， 本体 （4) 之柱面上径向开有通孔 （3 )。  A cervical interbody fusion pedestal having a columnar body (4) with a central hole (2), wherein the body (4) is made of fresh and healthy mammalian bones, and is fresh and healthy. The body made of mammalian bones (4) has a circular cross section, and the upper and lower bottom surfaces of the cylindrical body (4) are convexly convex and distributed with convex teeth (1), and the radial surface of the body (4) There is a through hole (3).
2、 根据权利要求 1所.述的颈椎椎体间固定融合垫具， 其特征还 在于， 所述本体 （4) 截面呈多边形或矩形或椭圆形。  The cervical interbody fusion pedestal according to claim 1, further characterized in that the body (4) has a polygonal or rectangular or elliptical cross section.
PCT/CN2005/000003 2004-12-23 2005-01-04 A filling member for fixing and fusing together adjacent cervical vertebrae WO2006066466A1 (en)

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CN 200410047087 CN1795833A (en) 2004-12-23 2004-12-23 Fixing fusion pad vertebral bodies of cervical vertebra
CN200410047087.4 2004-12-23

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