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WO2006065755A3 - Sels d'ammonium quaternaire d'amines heteroaromatiques fusionnees utilises comme nouveaux antagonistes du recepteur de l'acetylcholine muscarinique - Google Patents

Sels d'ammonium quaternaire d'amines heteroaromatiques fusionnees utilises comme nouveaux antagonistes du recepteur de l'acetylcholine muscarinique Download PDF

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Publication number
WO2006065755A3
WO2006065755A3 PCT/US2005/044951 US2005044951W WO2006065755A3 WO 2006065755 A3 WO2006065755 A3 WO 2006065755A3 US 2005044951 W US2005044951 W US 2005044951W WO 2006065755 A3 WO2006065755 A3 WO 2006065755A3
Authority
WO
WIPO (PCT)
Prior art keywords
amines
hetearomatic
fused
acetylcholine receptor
quaternary ammonium
Prior art date
Application number
PCT/US2005/044951
Other languages
English (en)
Other versions
WO2006065755A2 (fr
Inventor
Jakob Busch-Petersen
Roderick S Davis
Wei Fu
Jian Jin
Dramane I Laine
Michael R Palovich
Original Assignee
Glaxo Group Ltd
Jakob Busch-Petersen
Roderick S Davis
Wei Fu
Jian Jin
Dramane I Laine
Michael R Palovich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd, Jakob Busch-Petersen, Roderick S Davis, Wei Fu, Jian Jin, Dramane I Laine, Michael R Palovich filed Critical Glaxo Group Ltd
Publication of WO2006065755A2 publication Critical patent/WO2006065755A2/fr
Publication of WO2006065755A3 publication Critical patent/WO2006065755A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

L'invention concerne de nouveaux dérivés d'amines cycliques, des compositions pharmaceutiques, des procédés pour leur préparation ainsi que leur utilisation dans le traitement de maladies médiées par le récepteur de l'acétylcholine muscarinique.
PCT/US2005/044951 2004-12-13 2005-12-13 Sels d'ammonium quaternaire d'amines heteroaromatiques fusionnees utilises comme nouveaux antagonistes du recepteur de l'acetylcholine muscarinique WO2006065755A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63566404P 2004-12-13 2004-12-13
US60/635,664 2004-12-13

Publications (2)

Publication Number Publication Date
WO2006065755A2 WO2006065755A2 (fr) 2006-06-22
WO2006065755A3 true WO2006065755A3 (fr) 2006-10-12

Family

ID=36588443

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/044951 WO2006065755A2 (fr) 2004-12-13 2005-12-13 Sels d'ammonium quaternaire d'amines heteroaromatiques fusionnees utilises comme nouveaux antagonistes du recepteur de l'acetylcholine muscarinique

Country Status (1)

Country Link
WO (1) WO2006065755A2 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR045914A1 (es) 2003-07-17 2005-11-16 Glaxo Group Ltd Compuesto alcoholico terciario del 8-azoniabiciclo [3.2.1] octano, composicion farmaceutica que lo comprende y su uso para preparar esta ultima
ATE494285T1 (de) 2003-10-14 2011-01-15 Glaxo Group Ltd Muscarinische acetylcholin-rezeptor-antagonisten
EA200600787A1 (ru) 2003-10-17 2006-08-25 Глэксо Груп Лимитед Антагонисты мускариновых ацетилхолиновых рецепторов
AR046225A1 (es) 2003-11-04 2005-11-30 Glaxo Group Ltd Compuesto de 8-azoniabiciclo(3.2.1)octano, composicion farmaceutica para el tratamiento de enfermedades mediadas por receptores de acetilcolina muscarinicos que lo comprende y uso del compuesto para preparar dicha composicion
EP1725564A4 (fr) 2004-03-17 2007-09-12 Glaxo Group Ltd Antagonistes du recepteur d'acetylcholine muscarinique m3
PE20060259A1 (es) 2004-04-27 2006-03-25 Glaxo Group Ltd Compuestos de quinuclidina como antagonistas del receptor de acetilcolina muscarinico
EP1747219A4 (fr) 2004-05-13 2010-05-26 Glaxo Group Ltd Domaine de l'invention antagonistes récepteurs d'acétyle choline muscarinique
JP2008520579A (ja) 2004-11-15 2008-06-19 グラクソ グループ リミテッド 新規ｍ３ムスカリン性アセチルコリン受容体アンタゴニスト
EP1937068A4 (fr) 2005-08-18 2010-08-04 Glaxo Group Ltd Antagonistes de recepteurs d'acetylcholine muscarinique
WO2008116064A2 (fr) 2007-03-21 2008-09-25 Bristol-Myers Squibb Company Composés hétérocycliques fusionnés utiles en tant que modulateurs de kinases
UY31635A1 (es) 2008-02-06 2009-08-31 Farmacóforos duales-antagonistas muscarínicos de pde4
AR070562A1 (es) 2008-02-06 2010-04-21 Glaxo Group Ltd Farmacoforos duales - antagonistas muscarinicos de pde4
PE20091563A1 (es) 2008-02-06 2009-11-05 Glaxo Group Ltd Farmacoforos duales - antagonistas muscarinicos de pde4
WO2010094643A1 (fr) 2009-02-17 2010-08-26 Glaxo Group Limited Dérivés de quinoline et applications associées dans la rhinite et l'urticaire
BR122019025505B1 (pt) 2011-10-26 2022-02-22 Allergan, Inc Composição farmacêutica e uso da mesma
EP2838887B1 (fr) * 2012-04-16 2018-11-21 Allergan, Inc. Dérivés de (2-ureidoacétamido)alkyle utilisés en tant que modulateurs du récepteur à peptide formylé 2
TW201414737A (zh) 2012-07-13 2014-04-16 必治妥美雅史谷比公司 作爲激酶抑制劑之咪唑并三□甲腈
EP3795148A1 (fr) 2013-03-06 2021-03-24 Allergan, Inc. Utilisation d'agonistes du récepteur 2 de peptide formyle pour le traitement de maladies inflammatoires oculaires
JP6196328B2 (ja) 2013-03-06 2017-09-13 アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ 皮膚疾患を治療するためのホルミルペプチド受容体２アゴニストの使用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006065788A2 (fr) * 2004-12-13 2006-06-22 Glaxo Group Limited Nouveaux antagonistes du recepteur muscarinique de l'acetylcholine

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006065788A2 (fr) * 2004-12-13 2006-06-22 Glaxo Group Limited Nouveaux antagonistes du recepteur muscarinique de l'acetylcholine

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE CAS [online] accession no. STN Database accession no. (2006:605213) *

Also Published As

Publication number Publication date
WO2006065755A2 (fr) 2006-06-22

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