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WO2006051333A3 - Proteines contenant des motifs repetes riches en leucine (lrr) - Google Patents

Proteines contenant des motifs repetes riches en leucine (lrr) Download PDF

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Publication number
WO2006051333A3
WO2006051333A3 PCT/GB2005/004390 GB2005004390W WO2006051333A3 WO 2006051333 A3 WO2006051333 A3 WO 2006051333A3 GB 2005004390 W GB2005004390 W GB 2005004390W WO 2006051333 A3 WO2006051333 A3 WO 2006051333A3
Authority
WO
WIPO (PCT)
Prior art keywords
lrr
leucine
rich repeat
containing proteins
motif containing
Prior art date
Application number
PCT/GB2005/004390
Other languages
English (en)
Other versions
WO2006051333A2 (fr
Inventor
David Michalovich
Simon John White
Melanie Yorke
Kinsey Maundrell
Original Assignee
Ares Trading Sa
David Michalovich
Simon John White
Melanie Yorke
Kinsey Maundrell
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ares Trading Sa, David Michalovich, Simon John White, Melanie Yorke, Kinsey Maundrell filed Critical Ares Trading Sa
Priority to EP05803576A priority Critical patent/EP1814903A2/fr
Priority to CA002586486A priority patent/CA2586486A1/fr
Priority to AU2005303536A priority patent/AU2005303536A1/en
Priority to JP2007540722A priority patent/JP2008519593A/ja
Publication of WO2006051333A2 publication Critical patent/WO2006051333A2/fr
Publication of WO2006051333A3 publication Critical patent/WO2006051333A3/fr
Priority to IL182960A priority patent/IL182960A0/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cell Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

L'invention concerne des protéines, à savoir INSP168, INSP168-SV1, INSP149 et INSP169, identifiées en tant que protéines contenant des motifs répétés riches en leucine (LRR), et leur utilisation ainsi que des séquences d'acides nucléiques du gène de codage lors du diagnostic, de la prévention et du traitement d'une maladie.
PCT/GB2005/004390 2004-11-15 2005-11-15 Proteines contenant des motifs repetes riches en leucine (lrr) WO2006051333A2 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
EP05803576A EP1814903A2 (fr) 2004-11-15 2005-11-15 Proteines contenant des motifs repetes riches en leucine (lrr)
CA002586486A CA2586486A1 (fr) 2004-11-15 2005-11-15 Proteines contenant des motifs repetes riches en leucine (lrr)
AU2005303536A AU2005303536A1 (en) 2004-11-15 2005-11-15 Leucine-rich repeat (LRR) motif containing proteins
JP2007540722A JP2008519593A (ja) 2004-11-15 2005-11-15 ロイシンリッチリピート（ｌｒｒ）モチーフ含有タンパク質
IL182960A IL182960A0 (en) 2004-11-15 2007-05-03 Leucine-rich repeat (lrr) motif containing proteins

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0425197A GB0425197D0 (en) 2004-11-15 2004-11-15 Leucine-rich repeat (LRR) motif containing proteins
GB0425197.1 2004-11-15

Publications (2)

Publication Number Publication Date
WO2006051333A2 WO2006051333A2 (fr) 2006-05-18
WO2006051333A3 true WO2006051333A3 (fr) 2006-07-20

Family

ID=33523767

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2005/004390 WO2006051333A2 (fr) 2004-11-15 2005-11-15 Proteines contenant des motifs repetes riches en leucine (lrr)

Country Status (7)

Country Link
EP (1) EP1814903A2 (fr)
JP (1) JP2008519593A (fr)
AU (1) AU2005303536A1 (fr)
CA (1) CA2586486A1 (fr)
GB (1) GB0425197D0 (fr)
IL (1) IL182960A0 (fr)
WO (1) WO2006051333A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116036239B (zh) * 2023-03-28 2023-06-23 中国人民解放军军事科学院军事医学研究院 Nep1-40在制备特异性抑制幻觉作用的药物中的应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001128686A (ja) * 1999-11-09 2001-05-15 Tanabe Seiyaku Co Ltd 新規な蛋白質及びその遺伝子
WO2003054166A2 (fr) * 2001-12-20 2003-07-03 Incyte Genomics, Inc. Polymorphisme nucleotidiques associes a l'osteoarthrite
EP1447413A2 (fr) * 2003-02-14 2004-08-18 Research Association for Biotechnology ADN complementaire humaine de pleine longueur

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001128686A (ja) * 1999-11-09 2001-05-15 Tanabe Seiyaku Co Ltd 新規な蛋白質及びその遺伝子
WO2003054166A2 (fr) * 2001-12-20 2003-07-03 Incyte Genomics, Inc. Polymorphisme nucleotidiques associes a l'osteoarthrite
EP1447413A2 (fr) * 2003-02-14 2004-08-18 Research Association for Biotechnology ADN complementaire humaine de pleine longueur

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 19 May 2005 (2005-05-19), "TC102061 Human adult whole brain, large insert, pCMV expression library Homo sapiens cDNA clone TC102061 5' similar to Homo sapiens similar to retina specific protein PAL (LOC132703), mRNA sequence.", XP002378210, retrieved from EBI accession no. EM_PRO:DN994055 Database accession no. DN994055 *
DATABASE EMBL [online] 9 September 2003 (2003-09-09), "Homo sapiens cDNA FLJ44691 fis, clone BRACE3013874.", XP002378211, retrieved from EBI accession no. EM_PRO:AK126648 Database accession no. AK126648 *
GOMI F ET AL: "Molecular cloning of a novel membrane glycoprotein, Pal, specifically expressed in photoreceptor cells of the retina and containing leucine-rich repeat", JOURNAL OF NEUROSCIENCE, NEW YORK, NY, US, vol. 20, no. 9, 1 May 2000 (2000-05-01), pages 3206 - 3213, XP002229022, ISSN: 0270-6474 *
MUNFUS DELICIA L ET AL: "Identification of novel transmembrane molecules with leucine rich repeat, immunoglobulin and fibronectin domains.", FASEB JOURNAL, vol. 17, no. 4-5, March 2003 (2003-03-01), & FASEB MEETING ON EXPERIMENTAL BIOLOGY: TRANSLATING THE GENOME; SAN DIEGO, CA, USA; APRIL 11-15, 2003, pages Abstract No. 366.7 URL - http://ww, XP002378187, ISSN: 0892-6638 *
PATENT ABSTRACTS OF JAPAN vol. 2000, no. 22 9 March 2001 (2001-03-09) *

Also Published As

Publication number Publication date
CA2586486A1 (fr) 2006-05-18
GB0425197D0 (en) 2004-12-15
WO2006051333A2 (fr) 2006-05-18
EP1814903A2 (fr) 2007-08-08
AU2005303536A1 (en) 2006-05-18
IL182960A0 (en) 2007-08-19
JP2008519593A (ja) 2008-06-12

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