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WO2006050032A3 - Systeme et procede d'echantillonnage d'un analyte et analyse avec un hydrogel - Google Patents

Systeme et procede d'echantillonnage d'un analyte et analyse avec un hydrogel Download PDF

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Publication number
WO2006050032A3
WO2006050032A3 PCT/US2005/038785 US2005038785W WO2006050032A3 WO 2006050032 A3 WO2006050032 A3 WO 2006050032A3 US 2005038785 W US2005038785 W US 2005038785W WO 2006050032 A3 WO2006050032 A3 WO 2006050032A3
Authority
WO
WIPO (PCT)
Prior art keywords
analyte
biological membrane
electrode assembly
medium
based hydrogel
Prior art date
Application number
PCT/US2005/038785
Other languages
English (en)
Other versions
WO2006050032A2 (fr
WO2006050032A9 (fr
Inventor
Han Chuang
Shikha P Barman
Original Assignee
Sontra Medical Corp
Han Chuang
Shikha P Barman
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/223,971 external-priority patent/US8224414B2/en
Application filed by Sontra Medical Corp, Han Chuang, Shikha P Barman filed Critical Sontra Medical Corp
Priority to AU2005302584A priority Critical patent/AU2005302584B2/en
Priority to BRPI0517255-1A priority patent/BRPI0517255A/pt
Priority to JP2007539116A priority patent/JP5502279B2/ja
Priority to NZ554624A priority patent/NZ554624A/en
Priority to EP05824881A priority patent/EP1819283A4/fr
Priority to CA2584699A priority patent/CA2584699C/fr
Publication of WO2006050032A2 publication Critical patent/WO2006050032A2/fr
Publication of WO2006050032A3 publication Critical patent/WO2006050032A3/fr
Publication of WO2006050032A9 publication Critical patent/WO2006050032A9/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6802—Sensor mounted on worn items
    • A61B5/681—Wristwatch-type devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A61B5/1451—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
    • A61B5/14514—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150015—Source of blood
    • A61B5/150022—Source of blood for capillary blood or interstitial fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150053—Details for enhanced collection of blood or interstitial fluid at the sample site, e.g. by applying compression, heat, vibration, ultrasound, suction or vacuum to tissue; for reduction of pain or discomfort; Skin piercing elements, e.g. blades, needles, lancets or canulas, with adjustable piercing speed
    • A61B5/150061—Means for enhancing collection
    • A61B5/150083—Means for enhancing collection by vibration, e.g. ultrasound
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150358—Strips for collecting blood, e.g. absorbent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150969—Low-profile devices which resemble patches or plasters, e.g. also allowing collection of blood samples for testing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15134—Bladeless capillary blood sampling devices, i.e. devices for perforating the skin in order to obtain a blood sample but not using a blade, needle, canula, or lancet, e.g. by laser perforation, suction or pressurized fluids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/157—Devices characterised by integrated means for measuring characteristics of blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B2010/0003—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements including means for analysis by an unskilled person

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Optics & Photonics (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

L'invention porte sur un système de surveillance transdermique d'un analyste comprenant un support adapté pour s'interfacer avec une membrane biologique et pour accueillir un analyte provenant de la membrane biologique, et un ensemble électrode comprenant une pluralité d'électrodes. Le support est adapté pour réagir en continu avec l'analyte, un signal électrique est détecté par l'ensemble électrode et le signal électrique effectue une corrélation avec une valeur de l'analyte. La valeur de l'analyte peut être le flux de l'analyte dans la membrane biologique ou la concentration de l'analyte dans un flux biologique d'un sujet. Le support peut comprendre un hydrogène à base d'acétate vinylique, un hydrogène à base d'agarose ou un hydrogène à base de polyéthylène glycol diacrylate (PEG-DA), par exemple. La région superficielle de électrode peut comprendre un platine pur. Le système peut comprendre un filtre d'interférence placé entre la membrane biologique et l'ensemble électrode de façon à réduire les interférences dans le système. Le système peut comprendre un processeur programmé pour mettre en oeuvre un procédé de correction d'erreurs qui corrige la dérive du capteur.
PCT/US2005/038785 2004-10-28 2005-10-27 Systeme et procede d'echantillonnage d'un analyte et analyse avec un hydrogel WO2006050032A2 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
AU2005302584A AU2005302584B2 (en) 2004-10-28 2005-10-27 System and method for analyte sampling and analysis with hydrogel
BRPI0517255-1A BRPI0517255A (pt) 2004-10-28 2005-10-27 sistema e método para amostragem e análise de analito com hidrogel
JP2007539116A JP5502279B2 (ja) 2004-10-28 2005-10-27 ヒドロゲルを使用した検体のサンプリングおよび分析のためのシステムおよび方法
NZ554624A NZ554624A (en) 2004-10-28 2005-10-27 System and method for analyte sampling and analysis with hydrogel
EP05824881A EP1819283A4 (fr) 2004-10-28 2005-10-27 Systeme et procede d'echantillonnage d'un analyte et analyse avec un hydrogel
CA2584699A CA2584699C (fr) 2004-10-28 2005-10-27 Systeme et procede d'echantillonnage d'un analyte et analyse avec un hydrogel

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US97496304A 2004-10-28 2004-10-28
US10/974,963 2004-10-28
US20133405A 2005-08-11 2005-08-11
US11/201,334 2005-08-11
US11/223,971 US8224414B2 (en) 2004-10-28 2005-09-13 System and method for analyte sampling and analysis with hydrogel
US11/223,971 2005-09-13
US11/223,957 US20060094944A1 (en) 2004-10-28 2005-09-13 System and method for analyte sampling and analysis with error correction
US11/223,960 US20060094945A1 (en) 2004-10-28 2005-09-13 System and method for analyte sampling and analysis

Publications (3)

Publication Number Publication Date
WO2006050032A2 WO2006050032A2 (fr) 2006-05-11
WO2006050032A3 true WO2006050032A3 (fr) 2006-09-08
WO2006050032A9 WO2006050032A9 (fr) 2006-11-02

Family

ID=38441686

Family Applications (3)

Application Number Title Priority Date Filing Date
PCT/US2005/038786 WO2006050033A2 (fr) 2004-10-28 2005-10-27 Systeme et procede d'echantillonnage d'un analyte et analyse
PCT/US2005/038784 WO2006050031A2 (fr) 2004-10-28 2005-10-27 Systeme et procede d'echantillonnage et d'analyse d'analyte a correction d'erreur
PCT/US2005/038785 WO2006050032A2 (fr) 2004-10-28 2005-10-27 Systeme et procede d'echantillonnage d'un analyte et analyse avec un hydrogel

Family Applications Before (2)

Application Number Title Priority Date Filing Date
PCT/US2005/038786 WO2006050033A2 (fr) 2004-10-28 2005-10-27 Systeme et procede d'echantillonnage d'un analyte et analyse
PCT/US2005/038784 WO2006050031A2 (fr) 2004-10-28 2005-10-27 Systeme et procede d'echantillonnage et d'analyse d'analyte a correction d'erreur

Country Status (4)

Country Link
EP (1) EP1819283A4 (fr)
AU (1) AU2005302584B2 (fr)
CA (1) CA2584699C (fr)
WO (3) WO2006050033A2 (fr)

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EP1991113B1 (fr) 2006-02-27 2014-08-20 Edwards Lifesciences Corporation Membrane de limitation de flux pour biocapteur ampérométrique intraveineux
KR101433550B1 (ko) * 2007-03-07 2014-08-27 에코 테라퓨틱스, 인크. 경피 피분석물 모니터링 시스템 및 피분석물 검출 방법
WO2010013808A1 (fr) * 2008-07-31 2010-02-04 シスメックス株式会社 Procédé de dosage d'un composant in vivo, procédé de traitement de données pour le dosage d'un composant in vivo et appareil et élément de collecte pour le dosage d'un composant in vivo
US9216188B2 (en) 2008-09-04 2015-12-22 The General Hospital Corporation Hydrogels for vocal cord and soft tissue augmentation and repair
WO2010061386A2 (fr) * 2008-11-25 2010-06-03 B.G. Negev Technologies And Applications Ltd. Composition pharmaceutique et système pour la perméabilisation de membranes foetales
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EP3566649B1 (fr) 2009-03-02 2023-06-07 YourBio Health, Inc. Dispositifs de prélèvement de sang
US9198568B2 (en) 2010-03-04 2015-12-01 The General Hospital Corporation Methods and systems of matching voice deficits with a tunable mucosal implant to restore and enhance individualized human sound and voice production
US20120006100A1 (en) 2010-07-06 2012-01-12 Medtronic Minimed, Inc. Method and/or system for determining blood glucose reference sample times
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CA2833275C (fr) 2011-04-29 2021-06-15 Seventh Sense Biosystems, Inc. Distribution ou reception de fluides corporels
US20130158468A1 (en) 2011-12-19 2013-06-20 Seventh Sense Biosystems, Inc. Delivering and/or receiving material with respect to a subject surface
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US10898116B2 (en) 2013-03-15 2021-01-26 Cambridge Medical Technologies LLC Methods of manufacture to optimize performance of transdermal sampling and analysis device
KR102478639B1 (ko) 2016-02-23 2022-12-19 노을 주식회사 표지 물질을 저장하는 패치, 이를 이용하는 조직 진단 방법 및 장치
KR20170099737A (ko) 2016-02-23 2017-09-01 노을 주식회사 접촉식 염색 패치 및 이를 이용하는 염색 방법
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US6212416B1 (en) * 1995-11-22 2001-04-03 Good Samaritan Hospital And Medical Center Device for monitoring changes in analyte concentration
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Also Published As

Publication number Publication date
AU2005302584A1 (en) 2006-05-11
CA2584699C (fr) 2015-12-08
CA2584699A1 (fr) 2006-05-11
EP1819283A2 (fr) 2007-08-22
WO2006050031A9 (fr) 2006-06-15
EP1819283A4 (fr) 2011-08-10
WO2006050033A9 (fr) 2007-02-01
WO2006050032A2 (fr) 2006-05-11
WO2006050033B1 (fr) 2006-12-14
AU2005302584B2 (en) 2011-08-11
WO2006050032A9 (fr) 2006-11-02
WO2006050031A2 (fr) 2006-05-11
WO2006050033A3 (fr) 2006-11-02
WO2006050031A3 (fr) 2007-05-18
WO2006050033A2 (fr) 2006-05-11

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