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WO2006047977A1 - Stent destine a etre implante a l'interieur ou autour d'un organe creux, comportant des elements marqueurs constitues d'un materiau opaque aux rayons x - Google Patents

Stent destine a etre implante a l'interieur ou autour d'un organe creux, comportant des elements marqueurs constitues d'un materiau opaque aux rayons x Download PDF

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Publication number
WO2006047977A1
WO2006047977A1 PCT/DE2005/001661 DE2005001661W WO2006047977A1 WO 2006047977 A1 WO2006047977 A1 WO 2006047977A1 DE 2005001661 W DE2005001661 W DE 2005001661W WO 2006047977 A1 WO2006047977 A1 WO 2006047977A1
Authority
WO
WIPO (PCT)
Prior art keywords
stent
elements
stent according
marker
receiving elements
Prior art date
Application number
PCT/DE2005/001661
Other languages
German (de)
English (en)
Inventor
Johannes Jung
Original Assignee
Campus Gmbh & Co. Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Campus Gmbh & Co. Kg filed Critical Campus Gmbh & Co. Kg
Priority to DE112005002918T priority Critical patent/DE112005002918A5/de
Publication of WO2006047977A1 publication Critical patent/WO2006047977A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/91533—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other characterised by the phase between adjacent bands
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/9155—Adjacent bands being connected to each other
    • A61F2002/91558—Adjacent bands being connected to each other connected peak to peak
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0096—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers
    • A61F2250/0098—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers radio-opaque, e.g. radio-opaque markers

Definitions

  • the invention relates to a stent for implantation in or around a hollow organ with marker elements from a radiopaque material of the kind mentioned in the preamble of claim 1, and to a method for its production.
  • Stents are usually used in tubular hollow organs in order to expand or keep them open. They form a tube-like structure, which in their tube interior, the flow of body fluids or other physiological substances such. As food allows, wherein the Röh ⁇ renäußere rests against the surrounding hollow organ and this supports. They usually have a latticed or spiral
  • Structure consisting of wall segments. Grid openings are formed between and within the wall segments which make it possible for this structure to grow into the tissue at its implantation site.
  • Such stents are known per se and described for example in DE-A 197 46 88 or in WO 03/063 733.
  • stents are mounted on a balloon catheter, which is then introduced into the hollow organ to be treated.
  • This may be, for example, a coronary artery affected by a stenosis.
  • the balloon catheter is then dilated in order, on the one hand, to open the plaques causing the stenosis to or through the vessel wall press and thereby eliminate the stenosis and on the other hand to place the unfolded by the dilatation of the balloon catheter stent, which then ensures that the hollow organ retains its clearance.
  • self-expanding stents are used, which are introduced into the hollow organ in a first state of small diameter and then expand on their own in place into a second state with a larger diameter by an intrinsic spring force or are actively expanded.
  • stents in question which are made of a shape memory material.
  • rivet-shaped marker elements made of X-ray opaque material, which are in eye-shaped receiving elements of the lattice-shaped wall structure of the stent be fit form fit.
  • This type of design entails the risk that the rivet loses its positive fit due to mechanical stress or corrosion, z. B. in the.
  • the rivet head breaks, and then dissolves, escapes into the lumen of the stent and enters the hollow organ where it can cause serious complications, such as the occlusion of a blood vessel.
  • the object of the present invention is to provide a stent with marker elements made of an X-ray opaque material, which ensures permanent localizability within the hollow organ, and whose elasticity is not impaired by the marker elements. In addition, it should be ensured that the marker elements under no circumstances escape into the lumen of the stent and can enter the hollow organ.
  • a stent of the generic type which has a tubular grid wall running around a longitudinal axis made of elastic, in particular radially elastic wall segments which are arranged circumferentially one behind the other along the longitudinal axis and interconnected via connecting elements.
  • the stent has tube ends located at opposite axis ends.
  • the wall segments have spring elements with an elastic structure and receiving elements that are connected to the spring elements.
  • the receiving elements have cavities or recesses in the form of cavities, gaps, holes and / or recesses in which marker elements are arranged from a radiopaque material.
  • the receiving elements may be formed widened area compared to the spring elements.
  • the recesses may be configured, for example, in the form of recesses.
  • the stent according to the invention is characterized in that the recesses in the direction of the longitudinal axis have tapered, in particular conically tapered, Quer4.000s ⁇ surfaces and the radiopaque marker elements are conical and are arranged radially to the longitudinal axis in the recesses of the receiving elements.
  • the marker elements are thus arranged in the receiving elements similar to the capstone of a Roman vault.
  • the marker elements can not move in the tapering direction of the cross-sectional areas of the recesses, even if they break or corrode, and therefore can under no circumstances escape into the lumen of the stent.
  • the marker elements can in any case come off against the direction of tapering of the cross-sectional areas of the recesses, ie in the direction of the wall of the hollow organ where they cause no damage.
  • the recesses and the marker elements have round cross sections, and the marker elements are formed radially conically in the form of truncated cones.
  • round cross sections is to be understood as meaning circular, oval and elliptoid cross sections.
  • the recesses and the marker elements have substantially rectangular cross-sections, and the marker elements are conical in the form of truncated pyramids.
  • substantially rectangular cross-section "cuts" should also fall such cross sections, which go back to rectangles whose corners were rounded.
  • the marker elements are welded on their side remote from the longitudinal axis with the receiving elements and locked in this way permanently in the recesses.
  • welding points are set in the transition region between the receiving elements and the marker elements, for which purpose a laser can be used, for example.
  • the receiving elements are arranged at the tube ends of the stent. In this way, it is ensured that the ends of the stent can be reliably addressed in the X-ray image during the catheter operation or during a follow-up examination and thus the correct position of the stent can be checked.
  • receiving elements are arranged in the region between the tube ends.
  • these can be arranged on a line running around the grid wall in a helical line. In this way it can be determined in the X-ray image, whether the stent has been unfolded in place evenly and correctly.
  • the receiving elements are arranged circumferentially at the tube ends of the stent, thus forming a terminal, lying on the inside or outside of the hollow organ garland radiopaque markers.
  • the receiving elements are curved in a circular arc around the longitudinal axis of the stent transversely to their longitudinal direction.
  • the support effect at the tube ends may be impaired, since less supporting material is available here than in the region between the tube ends.
  • the length of the effective supportive area of the stent is therefore usually less than the absolute length of the stent itself.
  • terminal spring elements are arranged circumferentially at the tube ends in addition to the receiving elements. These terminal spring elements may be wider than the previously described spring elements in the region between the tube ends.
  • the receiving elements and the terminal spring elements are arranged cir ⁇ cumferentially alternately with each other.
  • the advantage of these embodiments is that the tube ends of the stent in the deployed state exert a better support on the vessel wall, with the result that the length of the effect of the stent, ie the region in which e.g. a restenosis can be effectively prevented is significantly greater.
  • the terminal spring element and the receiving elements are designed and / or arranged such that the ends of the elements pointing in the direction of the tube or stent ends have a circular, transversely to the longitudinal axis Describe arranged circumferential line, so it is arranged flush as it were.
  • This arrangement has the particular advantage that when placing the stent, i. when pushing forward with the help of a catheter, the pressure is distributed more evenly over the entire end peripheral surface of the stent.
  • the risk that a sealed marker peels off or even breaks greatly reduced.
  • the risk is reduced that individual terminal elements bend and possibly cut into the vessel wall.
  • the terminal spring elements are preferably wider, in particular at least twice as wide, configured as the wall segments.
  • the connecting elements and the spring elements form at least one continuous longitudinal web which extends in the longitudinal direction of the stent and the at least one component in the axial direction for receiving a compressive or tensile stress in the longitudinal direction.
  • the wall segments are particularly effectively positioned to each other, at the same time a change in length of the stent is reliably prevented.
  • the longitudinal web or the longitudinal webs has a helical wall surrounding the lattice wall or have.
  • This type of configuration can be produced particularly easily from a hollow cylinder by means of cutting, in particular laser and / or water jet cutting.
  • length changes due to compressive or tensile stresses or by compression of the stent are avoided as part of the forces occurring in the intended use reliably.
  • Ver ⁇ connecting elements are formed widened area compared to the spring elements.
  • This type of configuration can be easily produced by means of laser cutting.
  • Zu ⁇ before the deployment of the stenthuisele ⁇ elements are then formed, for example, slightly S-shaped.
  • the connecting elements In the unfolded state with a larger diameter, the connecting elements then have at least one component arranged parallel to the longitudinal web and support this in the effect described above.
  • the connecting elements have twice the width of the spring elements. This results in a particularly simple cutting pattern.
  • the connecting elements are shorter than the spring elements and expediently have a maximum length of 3/4, preferably a maximum 2/3 of the length of a spring element. Particularly preferred are lengths of 1/2 or less of the length of a spring element.
  • the radiopaque marker elements of the stent according to the invention preferably consist of a material which is selected from the group consisting of gold, platinum, silver, tantalum, plastic doped with barium sulfate and plastic doped with bismuth trioxide.
  • a material which is selected from the group consisting of gold, platinum, silver, tantalum, plastic doped with barium sulfate and plastic doped with bismuth trioxide may as well be used.
  • the spring, connecting and / or receiving elements of the stent according to the invention particularly preferably consist of a shape memory material.
  • the shape memory materials to be used are selected from the group consisting of nickel-titanium alloys and copper-zinc-aluminum alloys.
  • the nickel-titanium alloy nitinol has proven to be particularly suitable.
  • a hollow cylinder made of such material can, for example by means of a cutting technique, such. B. by means of laser or water jet, a substantially consisting of spring elements, connecting elements and receiving elements existing stent are cut out, the subsequently unfolded, the Harmon ⁇ diameter of the hollow organ to be treated corresponding shape can be impressed on known for Formge ⁇ memory materials. If the stent thus produced is subsequently compressed to the state of small diameter and, for example, introduced into a stenosed blood vessel with the aid of a catheter, the stent can be brought back into the previously impressed shape by heating to above the so-called conversion temperature. Optionally, this unfolding process can be assisted by use of a balloon catheter or completely replaced by it.
  • the spring, connecting and / or receiving elements can also consist of materials which are selected from the group consisting of stainless steel, plastic, or self-dissolving materials. Since these materials have no shape memory properties, the stents made from them have to be unfolded in situ with the aid of a balloon catheter. In particular, the self-dissolving materials are advantageous if a stent is not to be permanently applied.
  • the surface of the stent according to the invention is processed, in particular finished, smoothed, and / or polished. In this way, a smooth surface results, which in particular satisfies the requirements of the biocompatibility of the stent.
  • a method for producing a stent according to the invention in which the conical radiopaque marker elements are inserted from the side of the stent facing away from the longitudinal axis into the receiving elements and on this side by setting welding points on the receiving elements be attached.
  • a hollow cylinder consisting of a material which is selected from the group made of stainless steel, plastic, a self-dissolving Mate ⁇ material or a shape memory material, a tubular stent blank is cut out.
  • the spring, connecting and / or receiving elements of the wall segments by means of laser or Wasser ⁇ jet cutting are made from the stent blank.
  • FIG. 1 is a schematic representation of a stent 10 according to the invention in an unwound representation
  • FIG. 2 is an enlarged fragmentary view of the end portion of the stent shown in FIG. 1;
  • FIG. 3 is a plan view of a section along the line A - A in Fig. 2nd
  • FIG. 1 shows a schematic plan view of a stent 10 which is not yet expanded.
  • the stent 10 is cut out of a tube made of a suitable material, for example a shape memory material, by means of laser radiation.
  • the stent 10 has a longitudinal axis 11 and a grid wall 12, which is constructed from the individual wall segments 13.
  • the wall segments 13 consist of Fe ⁇ elements 16 arranged parallel to one another, which are connected via connecting elements 14 with spring elements 16 from the adjacent wall segment 13.
  • the stent 10 has receiving elements 17 arranged at the tube end 15, which are designed in the shape of an eye and have recesses 18 in which marker elements 19 of a radiopaque material, such as tantalum, are arranged.
  • the Recesses 18 and the marker elements 19 have an oval cross-section.
  • the stent also has terminal, preferably finger-like spring elements 20, wherein these and the receiving elements 17 are designed and arranged in such a way that the ends of the elements 20, 19 pointing in the direction of the tube ends 15 are flush and form a circular, Describe transverse to the longitudinal axis 11 of the stent 10 arranged circumferential line.
  • the advantage of this embodiment is that the tube ends 15 of the stent 10 in the deployed state exert a better support on the vessel wall, with the result that the effective length of the stent, ie the region in which e.g. a restenosis can be effectively prevented, is significantly greater.
  • this design has the advantage that when placing the stent 10, i. when pushing forward with the aid of a catheter, the pressure is distributed more uniformly over the entire end circumferential surface of the stent 10 and thus prevents individual terminal elements 17, 20 from cutting into the vessel wall.
  • Fig. 1 also reveals the approximately S-shaped configuration of the connecting elements 14. It is also clear in the figure that wall segments 13 arranged adjacent to one another are each arranged offset from one another, preferably by the width of two spring elements 16.
  • the connecting elements 14 and spring elements 16 thus form a continuous longitudinal web which has a component in the axial direction of the stent for absorbing compressive or tensile stresses in the longitudinal direction. Due to the described offset, the longitudinal web on a grid wall 12 of the stent 10 helically encircling shape.
  • the stent 10 produced in this way is expanded into a second state, which has a larger diameter than the first state. This second state is then impressed on the stent 10 in a known manner.
  • the stent 10 thus prepared is then compressed into a state having a small diameter. After the desired positioning, the stent 10 can then be expanded again by heating above the so-called conversion temperature into the imprinted form of the second state.
  • FIG. 2 shows an enlarged partial view of the end region of the stent 10 shown in FIG. 1 with the connecting elements 14, the spring elements 16, the recesses 18 of the receiving elements 17 and the marker elements 19 arranged therein, as well as the terminal spring elements 20.
  • the marker elements 19 are fastened in the receiving elements 17 by means of welding points 21 on the side of the stent facing away from the longitudinal axis.
  • FIG. 3 shows a plan view of a section through a stent 10 according to the invention along the line A-A in FIG. 2. Shown is a receiving element 17, a recess 18, a marker element 19 arranged in the recess 18, two terminal spring elements 20 as well as two welding points 21.
  • the receiving element 17 is curved arcuately around the longitudinal axis 11 of the stent 10 transversely to its longitudinal direction.
  • the recess 18 has tapered cross-sectional areas in the direction of the longitu ⁇ dinalen axis 11.
  • the radiopaque marker element 19 has a conical design and is arranged radially to the longitudinal axis 11 in the recess 18 of the receiving element 17. The marker element 19 is thus similar to the capstone of a Roman vault in the receiving element 17 Auf ⁇ arranged.
  • the marker element 19 can not move in the direction of tapering of the cross-sectional areas of the recess 18, even if it breaks or corrodes. At most, it can come off against the direction of the rejuvenation of the cross-sectional surfaces of the recess 18, that is to say in the direction of the wall of the hollow organ, where it causes no damage.
  • the recess 18 and the marker elements 19 can have round or substantially rectangular cross sections, and that the marker elements can be formed radially conically in the form of truncated cones or conically in the form of pyramidal stumps.
  • round cross-sections should be understood to mean circular, oval and elliptoid cross-sections.
  • substantially rectangular cross-sections should also include those cross-sections which can be traced back to corners with rounded corners.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Optics & Photonics (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Physics & Mathematics (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

L'invention concerne un stent (10) destiné être implanté à l'intérieur ou autour d'un organe creux, comportant des éléments marqueurs (19) constitués d'un matériau opaque aux rayons X. Ce stent comporte des éléments de logement (17) qui sont raccordés à des éléments ressort (15) et présentent des évidements (18) dans lesquels sont placés les éléments marqueurs (19) constitués d'un matériau opaque aux rayons X. Ce stent est caractérisé en ce que: les éléments de logement (17) sont courbés en arc de cercle autour de l'axe longitudinal (11) du stent (10); les évidements (18) présentent un diamètre diminuant en direction de l'axe longitudinal (11); et les éléments marqueurs (19) opaques aux rayons X présentent une forme conique dans le sens radial et sont placés radialement par rapport à l'axe longitudinal (11) dans les évidements (18) des éléments de logement (17).
PCT/DE2005/001661 2004-09-22 2005-09-21 Stent destine a etre implante a l'interieur ou autour d'un organe creux, comportant des elements marqueurs constitues d'un materiau opaque aux rayons x WO2006047977A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE112005002918T DE112005002918A5 (de) 2004-09-22 2005-09-21 Stent zur Implantation in oder um ein Hohlorgan mit Markerelementen aus einem röntgenopaken Material

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102004045994.0 2004-09-22
DE200410045994 DE102004045994A1 (de) 2004-09-22 2004-09-22 Stent zur Implantation in oder um ein Hohlorgan mit Markerelementen aus einem röntgenopaken Material

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Publication Number Publication Date
WO2006047977A1 true WO2006047977A1 (fr) 2006-05-11

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Cited By (13)

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Publication number Priority date Publication date Assignee Title
WO2008119837A2 (fr) 2007-04-03 2008-10-09 Angiomed Gmbh & Co. Medizintechnik Kg Endoprothèse pliable
US8152842B2 (en) 2006-08-21 2012-04-10 C. R. Bard, Inc. Self-expanding stent
US8322593B2 (en) 2006-08-23 2012-12-04 C. R. Bard, Inc. Method of welding a component to a shape memory alloy workpiece with provision of an extra cut for compensating the variations of dimension of workpiece and component
US8403978B2 (en) 2006-05-17 2013-03-26 C. R. Bard, Inc. Bend-capable tubular prosthesis
US8475520B2 (en) 2006-12-06 2013-07-02 C. R. Bard, Inc. Stenting ring with marker
US8500793B2 (en) 2006-09-07 2013-08-06 C. R. Bard, Inc. Helical implant having different ends
USRE44463E1 (en) 2000-08-18 2013-08-27 Angiomed Gmbh & Co. Medizintechnik Kg Implant with attached element and method of making such an implant
US8551156B2 (en) 2006-11-10 2013-10-08 C. R. Bard, Inc. Stent
US8574286B2 (en) 2006-05-18 2013-11-05 C. R. Bard, Inc. Bend-capable stent prosthesis
US8721709B2 (en) 2007-09-07 2014-05-13 C. R. Bard, Inc. Self-expansible stent with radiopaque markers and method of making such a stent
WO2015141399A1 (fr) * 2014-03-17 2015-09-24 テルモ株式会社 Système de pose d'objets à demeure
US9254207B2 (en) 2006-08-29 2016-02-09 C.R. Bard, Inc. Annular mesh
CN110420074A (zh) * 2019-06-27 2019-11-08 深圳市先健畅通医疗有限公司 覆膜支架

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