WO2005124365B1 - Tapered cuvette and method of collecting magnetic particles - Google Patents
Tapered cuvette and method of collecting magnetic particlesInfo
- Publication number
- WO2005124365B1 WO2005124365B1 PCT/US2005/019997 US2005019997W WO2005124365B1 WO 2005124365 B1 WO2005124365 B1 WO 2005124365B1 US 2005019997 W US2005019997 W US 2005019997W WO 2005124365 B1 WO2005124365 B1 WO 2005124365B1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- vessel
- sides
- magnetic particles
- vessels
- fluid
- Prior art date
Links
- 239000006249 magnetic particle Substances 0.000 title claims abstract 13
- 238000000034 method Methods 0.000 title claims abstract 7
- 239000012530 fluid Substances 0.000 claims abstract 9
- 239000012780 transparent material Substances 0.000 claims 1
- 238000005406 washing Methods 0.000 claims 1
Abstract
A vessel for use in clinical analysis including an open top, a closed bottom, and at least four tapered sides. A method for collecting magnetic particles in a fluid comprising the steps of providing a magnet and a vessel containing magnetic particles in a fluid, attracting the magnetic particles to the magnet, and moving the magnetic particles with the magnet out of the fluid.
Claims
1. A vessel for use in clinical analysis, comprising: a) a vertical axis; b) an open top substantially perpendicular to said vertical axis; c) a closed bottom; d) at least four sides, each of the four sides extending from the open top to the closed bottom, at least two of the at least four sides are flat and opposite to each other, at least two of the at least four sides are wider at the top than at the bottom of the vessel, and at least two of the at least four sides further comprise a projection positioned on the exterior surface of the vessel adjacent said open top, said projection comprising a planar surface substantially parallel to the vertical axis of the vessel
2. The vessel of claim 1 wherein the closed bottom is convex,
3. The vessel of claim 1 wherein opposite sides are symmetrical.
4. The vessel of claim 1 wherein the combined surface area of a pair of opposite sides is greater than the combined surface area of the other sides.
5. The vessel of claim 1 wherein the ratio of the combined surface area of opposite sides to the combined surface area of non-opposite sides is in the range of about 4;1 to about 2:1.
6. The vessel of claim 5 wherein the ratio is about 3:1.
7. The vessel of claim 1 wherein at least one pair of opposite sides is composed of a substantially transparent material.
8. The vessel of claim 1 wherein the interior cross-sectional area of the vessel is greater at the top of the vessel than at the bottom of the vessel.
9. The vessel of claim 1 wherein at least two of the sides are tapered at an angle of 5.8 degrees relative to the vertical.
10. The vessel of claim 1 wherein the vessel further comprises a flange positioned at the top of the vessel,
11. The vessel of claim 10 wherein the vessel comprises two flanges that extend 1.33 mm outward from the top of the vessel on opposite sides of the vessel.
12. The vessel of claim 10 wherein the flange extends substantially the same distance from the sides of the vessel on all sides.
13. The vessel of claim 1 wherein the top of the vessel further comprises a pxoj ection on an exterior surface of one side.
14. The vessel of claim 1 wherein the vessel is stacked with like vessels.
15. The vessel of claim 14 wherein the exterior surface of a first vessel and the interior surface of a second vessel define a gap between the first and second vessels of at least 0.01 mm.
16. The stack of vessels of claim 14 wherein the gap between the vessels is substantially equivalent to the depth of the projection.
17. A vessel cartridge for loading vessels in an automated clinical diagnostic device, comprising a plurality of vessels, wherein the exterior surface of a first vessel and the interior surface of a second vessel define a space between the first and second vessels.
18. The vessel cartridge of claim 17 wherein the space between the first and second vessels is at least 4 mm.
19. The vessel cartridge of claim 17 wherein the space between the first and s econd vessels is further defined by a projection on the surface of the first vessel,
20. A method for collecting magnetic particles comprising the steps of; a) providing a magnet and a vessel containing magnetic particles in a fluid; b) attracting the magnetic particles to the magnet; c) moving the magnetic particles with the magnet out of the fluid.
21. The method of claim 20 wherein the method further comprises the step of removing the fluid from the vessel after the magnetic particles have been moved out of the fluid.
22. The method of claim 20 wherein the magnet is moved to move the magnetic particles out of the fluid.
23. The method of claim 20 wherein the vessel is moved to move the magnetic particles out of the fluid.
24. A device for washing magnetic particles in a vessel, comprising: a holder comprising a lumen for receiving the vessel in a tilted position, the holder comprising a straight side and a sloped side opposite to the straight side, the sloped side comprising a lever arm wherein said lever arm is reciprocally moveable from a position within said holder lumen to a position outside said holder lumen, and said lever aπn is biased toward said holder lumen to retain said vessel in said holder lumen in said titled position.
25. The device of claim 24 wherein said lever arm comprises a spring.
26. The device of claim 24 further comprising a magnet.
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2005255403A AU2005255403B2 (en) | 2004-06-08 | 2005-06-07 | Tapered cuvette and method of collecting magnetic particles |
| JP2007527655A JP4987713B2 (en) | 2004-06-08 | 2005-06-07 | Tapered cuvette and method for collecting magnetic particles |
| CA2570133A CA2570133C (en) | 2004-06-08 | 2005-06-07 | Tapered cuvette and method of collecting magnetic particles |
| EP05758474.0A EP1754065B1 (en) | 2004-06-08 | 2005-06-07 | Tapered cuvette and method of collecting magnetic particles |
| ES05758474.0T ES2554921T3 (en) | 2004-06-08 | 2005-06-07 | Tapered cuvette and magnetic particle collection method |
| AU2010221789A AU2010221789B2 (en) | 2004-06-08 | 2010-09-15 | A vessel and method for collecting magnetic particles |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/863,881 US8211386B2 (en) | 2004-06-08 | 2004-06-08 | Tapered cuvette and method of collecting magnetic particles |
| US10/863,881 | 2004-06-08 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| WO2005124365A2 WO2005124365A2 (en) | 2005-12-29 |
| WO2005124365A3 WO2005124365A3 (en) | 2006-02-16 |
| WO2005124365B1 true WO2005124365B1 (en) | 2006-04-06 |
Family
ID=34972154
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/US2005/019997 WO2005124365A2 (en) | 2004-06-08 | 2005-06-07 | Tapered cuvette and method of collecting magnetic particles |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US8211386B2 (en) |
| EP (2) | EP2634585A3 (en) |
| JP (3) | JP4987713B2 (en) |
| AU (2) | AU2005255403B2 (en) |
| CA (2) | CA2901298A1 (en) |
| ES (1) | ES2554921T3 (en) |
| WO (1) | WO2005124365A2 (en) |
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2004
- 2004-06-08 US US10/863,881 patent/US8211386B2/en active Active
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2005
- 2005-06-07 WO PCT/US2005/019997 patent/WO2005124365A2/en not_active Application Discontinuation
- 2005-06-07 EP EP13169928.2A patent/EP2634585A3/en not_active Withdrawn
- 2005-06-07 CA CA2901298A patent/CA2901298A1/en not_active Abandoned
- 2005-06-07 ES ES05758474.0T patent/ES2554921T3/en active Active
- 2005-06-07 CA CA2570133A patent/CA2570133C/en active Active
- 2005-06-07 AU AU2005255403A patent/AU2005255403B2/en not_active Ceased
- 2005-06-07 JP JP2007527655A patent/JP4987713B2/en not_active Expired - Fee Related
- 2005-06-07 EP EP05758474.0A patent/EP1754065B1/en active Active
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2010
- 2010-09-15 AU AU2010221789A patent/AU2010221789B2/en not_active Ceased
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2012
- 2012-03-08 US US13/415,476 patent/US8476080B2/en not_active Expired - Lifetime
- 2012-03-12 JP JP2012054478A patent/JP5795973B2/en not_active Expired - Fee Related
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2013
- 2013-06-20 US US13/922,370 patent/US20130287651A1/en not_active Abandoned
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2014
- 2014-01-10 JP JP2014003045A patent/JP2014089210A/en active Pending
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