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WO2005011593A3 - Improved binding of pantoprazole to the acid pump - Google Patents

Improved binding of pantoprazole to the acid pump Download PDF

Info

Publication number
WO2005011593A3
WO2005011593A3 PCT/US2004/024678 US2004024678W WO2005011593A3 WO 2005011593 A3 WO2005011593 A3 WO 2005011593A3 US 2004024678 W US2004024678 W US 2004024678W WO 2005011593 A3 WO2005011593 A3 WO 2005011593A3
Authority
WO
WIPO (PCT)
Prior art keywords
pantoprazole
improved binding
acid pump
acid
pump
Prior art date
Application number
PCT/US2004/024678
Other languages
French (fr)
Other versions
WO2005011593A2 (en
Inventor
Richard J Heaslip
Original Assignee
Altana Pharma Ag
Richard J Heaslip
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag, Richard J Heaslip filed Critical Altana Pharma Ag
Publication of WO2005011593A2 publication Critical patent/WO2005011593A2/en
Publication of WO2005011593A3 publication Critical patent/WO2005011593A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to a certain form of pantoprazole, which selectively binds to the proton pump, thus improving the degree and the duration of acid inhibition.
PCT/US2004/024678 2003-07-31 2004-07-30 Improved binding of pantoprazole to the acid pump WO2005011593A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49127303P 2003-07-31 2003-07-31
US60/491,273 2003-07-31

Publications (2)

Publication Number Publication Date
WO2005011593A2 WO2005011593A2 (en) 2005-02-10
WO2005011593A3 true WO2005011593A3 (en) 2005-09-01

Family

ID=34115485

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/024678 WO2005011593A2 (en) 2003-07-31 2004-07-30 Improved binding of pantoprazole to the acid pump

Country Status (1)

Country Link
WO (1) WO2005011593A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102786483B (en) * 2011-05-19 2016-03-30 复旦大学 4-(4-Phenylpiperazinyl) pharmaceutical usage of quinazoline derivative

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994025028A1 (en) * 1993-04-27 1994-11-10 Sepracor, Inc. Methods and compositions for treating gastric disorders using optically pure (+) pantoprazole

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994025028A1 (en) * 1993-04-27 1994-11-10 Sepracor, Inc. Methods and compositions for treating gastric disorders using optically pure (+) pantoprazole

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CURRENT OPINION IN GASTEROENTEROLOGY, vol. 19, no. 6, 2003, pages 519 - 525 *
DATABASE BIOBASE [online] SCHUBERT M.K. ET AL: "Gastric Secretion", accession no. STN Database accession no. (2003267791) *

Also Published As

Publication number Publication date
WO2005011593A2 (en) 2005-02-10

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