+

WO2005098030A3 - Procede pour identifier des composes a action fongicide sur la base de thioredoxine reductases - Google Patents

Procede pour identifier des composes a action fongicide sur la base de thioredoxine reductases Download PDF

Info

Publication number
WO2005098030A3
WO2005098030A3 PCT/EP2005/002951 EP2005002951W WO2005098030A3 WO 2005098030 A3 WO2005098030 A3 WO 2005098030A3 EP 2005002951 W EP2005002951 W EP 2005002951W WO 2005098030 A3 WO2005098030 A3 WO 2005098030A3
Authority
WO
WIPO (PCT)
Prior art keywords
identification
fungicidally
compounds based
effective compounds
thioredoxin reductases
Prior art date
Application number
PCT/EP2005/002951
Other languages
German (de)
English (en)
Other versions
WO2005098030A2 (fr
Inventor
Edda Koopmann
Ruediger Suelmann
Peter Schreier
Birgitta Leuthner
Thorsten Leicher
Original Assignee
Bayer Cropscience Ag
Edda Koopmann
Ruediger Suelmann
Peter Schreier
Birgitta Leuthner
Thorsten Leicher
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Cropscience Ag, Edda Koopmann, Ruediger Suelmann, Peter Schreier, Birgitta Leuthner, Thorsten Leicher filed Critical Bayer Cropscience Ag
Publication of WO2005098030A2 publication Critical patent/WO2005098030A2/fr
Publication of WO2005098030A3 publication Critical patent/WO2005098030A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0036—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/37—Assays involving biological materials from specific organisms or of a specific nature from fungi

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La présente invention concerne un procédé pour identifier des fongicides, l'utilisation de thiorédoxine réductase fongique pour identifier des fongicides, et l'utilisation d'inhibiteurs de la thiorédoxine réductase comme fongicides.
PCT/EP2005/002951 2004-04-02 2005-03-19 Procede pour identifier des composes a action fongicide sur la base de thioredoxine reductases WO2005098030A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE200410016252 DE102004016252A1 (de) 2004-04-02 2004-04-02 Verfahren zum Indentifizieren von fungizid wirksamen Verbindungen basierend auf Thioredoxin Reduktasen
DE102004016252.2 2004-04-02

Publications (2)

Publication Number Publication Date
WO2005098030A2 WO2005098030A2 (fr) 2005-10-20
WO2005098030A3 true WO2005098030A3 (fr) 2006-04-20

Family

ID=34961813

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2005/002951 WO2005098030A2 (fr) 2004-04-02 2005-03-19 Procede pour identifier des composes a action fongicide sur la base de thioredoxine reductases

Country Status (2)

Country Link
DE (1) DE102004016252A1 (fr)
WO (1) WO2005098030A2 (fr)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003004479A1 (fr) * 2001-07-06 2003-01-16 Cancer Research Technology Limited 4-aryl quinols et leurs analogues utilises en tant qu'agents therapeutiques
WO2004006866A2 (fr) * 2002-07-12 2004-01-22 K.K. Gni Cibles therapeutiques antifongiques

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003004479A1 (fr) * 2001-07-06 2003-01-16 Cancer Research Technology Limited 4-aryl quinols et leurs analogues utilises en tant qu'agents therapeutiques
WO2004006866A2 (fr) * 2002-07-12 2004-01-22 K.K. Gni Cibles therapeutiques antifongiques

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ANKRI SERGE ET AL: "Antimicrobial properties of allicin from garlic", MICROBES AND INFECTION, ELSEVIER, PARIS, FR, vol. 1, no. 2, February 1999 (1999-02-01), pages 125 - 129, XP002289130, ISSN: 1286-4579 *
KUTTY G ET AL: "Characterization of thioredoxin reductase genes (trr1) from Pneumocystis carinii and Pneumocystis jiroveci", GENE: AN INTERNATIONAL JOURNAL ON GENES AND GENOMES, ELSEVIER SCIENCE PUBLISHERS, BARKING, GB, vol. 310, 22 May 2003 (2003-05-22), pages 175 - 183, XP004430579, ISSN: 0378-1119 *
MISSALL TRICIA A ET AL: "Thioredoxin reductase is essential for viability in the fungal pathogen Cryptococcus neoformans", EUKARYOTIC CELL, vol. 4, no. 2, February 2005 (2005-02-01), pages 487 - 489, XP002340315, ISSN: 1535-9778 *
PEDRAJAS JOSE R ET AL: "Identification and functional characterization of a novel mitochondrial thioredoxin system in Saccharomyces cerevisiae", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 274, no. 10, 5 March 1999 (1999-03-05), pages 6366 - 6373, XP002340316, ISSN: 0021-9258 *

Also Published As

Publication number Publication date
DE102004016252A1 (de) 2005-10-13
WO2005098030A2 (fr) 2005-10-20

Similar Documents

Publication Publication Date Title
WO2007024263A3 (fr) Foret d'electroconcassage portable
WO2008005375A3 (fr) Biomarqueurs de la néphrotoxicité
WO2006033720A3 (fr) Procede d'expansion
WO2007067923A3 (fr) Compositions et procedes de detection d'un phosphomonoester
WO2006053225A3 (fr) Nanoparticules metalliques riches en proteines
EP1917376A4 (fr) Acier fabrique a l'aide de la metallurgie des poudres, outil comprenant cet acier et procede de fabrication de cet outil
WO2008142795A1 (fr) Fluide fonctionnel
WO2006071762A3 (fr) Inhibiteurs de dipeptidyl-peptidase iv a base de pyrimidine et methodes associees
WO2009048101A1 (fr) Composé amide
WO2008055236A3 (fr) Inhibiteurs de kinase mapk/erk
WO2003102066A3 (fr) Dispersions aqueuses d'adhesif
WO2008063794A3 (fr) Composés d'oxazolidinium et utilisation en tant qu'inhibiteurs d'hydrate
WO2006127287A3 (fr) Inhibiteurs a base de pyrrolopyridine, pour inhiber la dipeptidyl peptidase iv, et procedes correspondants
WO2009075554A3 (fr) Procédé et système permettant de fournir des informations sur les brevets
WO2007050348A3 (fr) Inhibiteurs du canal potassique
WO2007062308A3 (fr) Inhibiteurs de cetp heterocycliques
WO2007062314A3 (fr) Inhibiteurs de cetp heterocycliques
WO2006056340A3 (fr) Methode de determination de la genotoxicite
WO2005114452A3 (fr) Architecture orientee services
WO2006039250A3 (fr) Sels de compose heterocyclique se liant aux chimiokines et procedes d'utilisation correspondants
EP1914065A4 (fr) Feuille d'acier stratifiée pour boîte en deux parties, procédé de fabrication de boîte en deux parties, et boîte stratifiée en deux parties
WO2010015635A3 (fr) Mélanges fongicides
WO2005085423A8 (fr) Expression d'oct-4 et de gjic en tant que marqueurs de cellules souches humaines adultes et precurseur de cellules cancereuses
WO2006004642A3 (fr) Composition d'enrobage de l'aluminium
WO2005002525A3 (fr) Inhibiteurs de cox -2 et de faah

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SM SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
NENP Non-entry into the national phase

Ref country code: DE

WWW Wipo information: withdrawn in national office

Country of ref document: DE

122 Ep: pct application non-entry in european phase
点击 这是indexloc提供的php浏览器服务，不要输入任何密码和下载