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WO2005065650A3 - Formulations - Google Patents

Formulations Download PDF

Info

Publication number
WO2005065650A3
WO2005065650A3 PCT/GB2004/004241 GB2004004241W WO2005065650A3 WO 2005065650 A3 WO2005065650 A3 WO 2005065650A3 GB 2004004241 W GB2004004241 W GB 2004004241W WO 2005065650 A3 WO2005065650 A3 WO 2005065650A3
Authority
WO
WIPO (PCT)
Prior art keywords
carboxylic acid
acid surfactant
aerosol formulations
surfactant
pharmaceutical formulations
Prior art date
Application number
PCT/GB2004/004241
Other languages
English (en)
Other versions
WO2005065650A2 (fr
Inventor
Craig Davies-Cutting
Tristan Fairbrother
Alexander J M Munro
Trevor Riley
Renata Zofia Williams
Original Assignee
Glaxo Group Ltd
Craig Davies-Cutting
Tristan Fairbrother
Alexander J M Munro
Trevor Riley
Renata Zofia Williams
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd, Craig Davies-Cutting, Tristan Fairbrother, Alexander J M Munro, Trevor Riley, Renata Zofia Williams filed Critical Glaxo Group Ltd
Priority to EP04820961A priority Critical patent/EP1684721A2/fr
Priority to JP2006530593A priority patent/JP2007508283A/ja
Publication of WO2005065650A2 publication Critical patent/WO2005065650A2/fr
Publication of WO2005065650A3 publication Critical patent/WO2005065650A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

L'invention concerne de nouvelles formulations pharmaceutiques de médicaments se présentant sous forme de particules, tels que des agonistes bêta et/ou des stéroïdes anti-inflammatoires dans des agents propulseurs d'hydrofluoroalcane comprenant un tensioactif d'acide carboxylique.
PCT/GB2004/004241 2003-10-09 2004-10-06 Formulations WO2005065650A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP04820961A EP1684721A2 (fr) 2003-10-09 2004-10-06 Formulations d'aerosol comprenant un tensio actif d'un acide carboxylique
JP2006530593A JP2007508283A (ja) 2003-10-09 2004-10-06 カルボン酸界面活性剤を含むエアロゾル製剤

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0323701.3 2003-10-09
GBGB0323701.3A GB0323701D0 (en) 2003-10-09 2003-10-09 Formulations

Publications (2)

Publication Number Publication Date
WO2005065650A2 WO2005065650A2 (fr) 2005-07-21
WO2005065650A3 true WO2005065650A3 (fr) 2006-04-27

Family

ID=29433610

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2004/004241 WO2005065650A2 (fr) 2003-10-09 2004-10-06 Formulations

Country Status (4)

Country Link
EP (1) EP1684721A2 (fr)
JP (1) JP2007508283A (fr)
GB (1) GB0323701D0 (fr)
WO (1) WO2005065650A2 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GT200500281A (es) 2004-10-22 2006-04-24 Novartis Ag Compuestos organicos.
GB0424284D0 (en) 2004-11-02 2004-12-01 Novartis Ag Organic compounds
GB0516313D0 (en) 2005-08-08 2005-09-14 Argenta Discovery Ltd Azole derivatives and their uses
US7994211B2 (en) 2005-08-08 2011-08-09 Argenta Discovery Limited Bicyclo[2.2.1]hept-7-ylamine derivatives and their uses
GB0601951D0 (en) 2006-01-31 2006-03-15 Novartis Ag Organic compounds
EP2013211B1 (fr) 2006-04-21 2012-03-14 Novartis AG Derives de purine utilises en tant que recepteurs agonist d'adenosin a2a
CA2711637A1 (fr) 2008-01-11 2009-07-16 Novartis Ag Pyrimidines utilises en tant qu'inhibiteurs de kinase
US8236786B2 (en) 2008-08-07 2012-08-07 Pulmagen Therapeutics (Inflammation) Limited Respiratory disease treatment
EA019441B1 (ru) 2008-12-30 2014-03-31 Палмаджен Терепьютикс (Инфлеммейшн) Лимитед Сульфонамиды, предназначенные для лечения респираторных нарушений
WO2010150014A1 (fr) 2009-06-24 2010-12-29 Pulmagen Therapeutics (Inflammation) Limited Glitazones 5r-5–deutérés pour le traitement de maladies respiratoires
GB0918923D0 (en) 2009-10-28 2009-12-16 Vantia Ltd Aminothiazole derivatives
GB0918924D0 (en) 2009-10-28 2009-12-16 Vantia Ltd Azaindole derivatives
GB0918922D0 (en) 2009-10-28 2009-12-16 Vantia Ltd Aminopyridine derivatives
WO2011098746A1 (fr) 2010-02-09 2011-08-18 Pulmagen Therapeutics (Inflammation) Limited Sels d'addition acide cristallins de l'énantiomère (5r) de la pioglitazone
GB201002224D0 (en) 2010-02-10 2010-03-31 Argenta Therapeutics Ltd Respiratory disease treatment
GB201002243D0 (en) 2010-02-10 2010-03-31 Argenta Therapeutics Ltd Respiratory disease treatment
WO2012034095A1 (fr) 2010-09-09 2012-03-15 Irm Llc Composés et compositions comme inhibiteurs de trk
UY33597A (es) 2010-09-09 2012-04-30 Irm Llc Compuestos y composiciones como inhibidores de la trk
GEP20156285B (en) 2011-02-25 2015-05-11 Aierem Elelsi Compounds and compositions as trk inhibitors

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002012265A1 (fr) * 2000-08-05 2002-02-14 Glaxo Group Limited 6.ALPHA., 9.ALPHA.-DIFLUORO-17.ALPHA.-`(2-FURANYLCARBOXYLE) OXY!-11.BETA.-HYDROXY-16.ALPHA.-METHYLE-3-OXO-ANDROST-1,4,-DIENE-17-ACIDE CARBOTHIOIQUE S-FLUOROMETHYLE ESTER UTILISE COMME AGENT ANTI INFLAMMATOIRE
WO2002066422A1 (fr) * 2001-02-14 2002-08-29 Glaxo Group Limited Derives de phenethanolamine pour le traitement de maladies respiratoires
WO2003013610A2 (fr) * 2001-08-03 2003-02-20 Glaxo Group Limited Composes d'agents de surface et leurs utilisations

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002012265A1 (fr) * 2000-08-05 2002-02-14 Glaxo Group Limited 6.ALPHA., 9.ALPHA.-DIFLUORO-17.ALPHA.-`(2-FURANYLCARBOXYLE) OXY!-11.BETA.-HYDROXY-16.ALPHA.-METHYLE-3-OXO-ANDROST-1,4,-DIENE-17-ACIDE CARBOTHIOIQUE S-FLUOROMETHYLE ESTER UTILISE COMME AGENT ANTI INFLAMMATOIRE
WO2002066422A1 (fr) * 2001-02-14 2002-08-29 Glaxo Group Limited Derives de phenethanolamine pour le traitement de maladies respiratoires
WO2003013610A2 (fr) * 2001-08-03 2003-02-20 Glaxo Group Limited Composes d'agents de surface et leurs utilisations

Also Published As

Publication number Publication date
EP1684721A2 (fr) 2006-08-02
WO2005065650A2 (fr) 2005-07-21
JP2007508283A (ja) 2007-04-05
GB0323701D0 (en) 2003-11-12

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