WO2005065050A3 - 2環化合物 - Google Patents
2環化合物 Download PDFInfo
- Publication number
- WO2005065050A3 WO2005065050A3 PCT/JP2004/019187 JP2004019187W WO2005065050A3 WO 2005065050 A3 WO2005065050 A3 WO 2005065050A3 JP 2004019187 W JP2004019187 W JP 2004019187W WO 2005065050 A3 WO2005065050 A3 WO 2005065050A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- salt
- compound
- hydroxy
- heterocyclic group
- bicyclic compound
- Prior art date
Links
- -1 Bicyclic compound Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000006615 aromatic heterocyclic group Chemical group 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 230000000849 parathyroid Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- C07C211/29—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/335—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/58—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2003429123 | 2003-12-25 | ||
JP2003-429123 | 2003-12-25 | ||
JP2004326560 | 2004-11-10 | ||
JP2004-326560 | 2004-11-10 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2005065050A2 WO2005065050A2 (ja) | 2005-07-21 |
WO2005065050A3 true WO2005065050A3 (ja) | 2005-09-15 |
Family
ID=34752056
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2004/019187 WO2005065050A2 (ja) | 2003-12-25 | 2004-12-22 | 2環化合物 |
Country Status (2)
Country | Link |
---|---|
US (1) | US7582658B2 (ja) |
WO (1) | WO2005065050A2 (ja) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008088594A2 (en) * | 2007-01-12 | 2008-07-24 | Anaptysbio, Inc. | Isolation of antibodies that cross-react and neutralize rankl orginating from multiple species |
US8648069B2 (en) | 2007-06-08 | 2014-02-11 | Abbvie Inc. | 5-substituted indazoles as kinase inhibitors |
DE102008022221A1 (de) | 2008-05-06 | 2009-11-12 | Universität des Saarlandes | Inhibitoren der humanen Aldosteronsynthase CYP11B2 |
US8674137B2 (en) | 2008-10-22 | 2014-03-18 | Acucela Inc. | Compounds for treating ophthalmic diseases and disorders |
WO2010136037A1 (en) | 2009-05-27 | 2010-12-02 | Leo Pharma A/S | Novel calcium sensing receptor modulating compounds and pharmaceutical use thereof |
WO2010136035A2 (en) | 2009-05-27 | 2010-12-02 | Leo Pharma A/S | Novel calcium sensing receptor modulating compounds and pharmaceutical use thereof |
US8541404B2 (en) * | 2009-11-09 | 2013-09-24 | Elexopharm Gmbh | Inhibitors of the human aldosterone synthase CYP11B2 |
EP2588445A1 (en) | 2010-06-30 | 2013-05-08 | Leo Pharma A/S | New polymorphic form of a calcimimetic compound |
RU2599788C2 (ru) | 2010-06-30 | 2016-10-20 | Лео Фарма А/С | Новая полиморфная форма кальцимиметического соединения |
RU2013128968A (ru) | 2010-11-26 | 2015-01-10 | Лео Фарма А/С | Соединения, активные в отношении кальций-чувствительного рецептора |
RU2013128981A (ru) | 2010-11-26 | 2015-01-10 | Лео Фарма А/С | Соединения, активные в отношении чувствительных к кальцию рецепторов |
JP2014507375A (ja) | 2010-11-26 | 2014-03-27 | レオ ファーマ アクティーゼルスカブ | カルシウム感知受容体活性化合物 |
WO2012069402A1 (en) | 2010-11-26 | 2012-05-31 | Leo Pharma A/S | Substituted cyclopentyl - azines as casr- active compounds |
CN103265543A (zh) | 2011-08-09 | 2013-08-28 | 丘比斯特药物股份有限公司 | 抑制瞬时受体电位离子通道trpa1 |
US9353081B2 (en) * | 2011-09-23 | 2016-05-31 | Hoffmann-La Roche Inc. | Bicyclic dihydroquinoline-2-one derivatives |
EP2945947B1 (en) * | 2013-01-18 | 2019-12-04 | Merck Sharp & Dohme Corp. | Inhibiting the transient receptor potential a1 ion channel |
US9394308B2 (en) | 2013-01-18 | 2016-07-19 | Merck Sharp & Dohme Corp. | Inhibiting the transient receptor potential A1 ion channel |
WO2016074696A1 (en) * | 2014-11-10 | 2016-05-19 | Givaudan Ag | Perfume ingredients and perfume preparations containing same |
WO2020007856A1 (en) * | 2018-07-02 | 2020-01-09 | Dsm Ip Assets B.V. | Process for the selective acylation of primary hydroxy groups in the presence of secondary hydroxy groups and catalyst therefor |
CN110938114B (zh) * | 2018-09-21 | 2023-04-28 | 中国科学院上海药物研究所 | 一类万古霉素硫鎓衍生物、其制备方法、药物组合物和用途 |
CN113272471B (zh) * | 2019-01-10 | 2023-07-18 | 中央硝子株式会社 | 基板、选择性膜沉积方法、有机物的沉积膜及有机物 |
CN112326820A (zh) * | 2020-10-22 | 2021-02-05 | 大连美创药业有限公司 | 一种艾地骨化醇血药浓度的高效液相色谱-质谱联用检测方法 |
CN113143936B (zh) * | 2021-02-10 | 2022-03-25 | 北京蕴汇医药科技有限公司 | 鹅去氧胆酸或其衍生物在制备egfr和/或stat3的抑制剂中的用途 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH04501722A (ja) * | 1988-11-14 | 1992-03-26 | ジ・アップジョン・カンパニー | 抗―糖尿病、抗―肥満症および抗―アテローム性動脈硬化症薬として有用なα―アミノ―インドール―3―酢酸 |
JPH07506380A (ja) * | 1993-02-23 | 1995-07-13 | ブリガム・アンド・ウイミンズ・ホスピタル・インコーポレイテッド | カルシウム受容体活性化分子およびその関連物 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0724561B1 (en) | 1991-08-23 | 2004-04-14 | Nps Pharmaceuticals, Inc. | Calcium receptor-active arylalkyl amines |
US6011068A (en) | 1991-08-23 | 2000-01-04 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
RU2147574C1 (ru) | 1991-08-23 | 2000-04-20 | Эн-Пи-Эс Фармасьютикалз, Инк. | Арилалкиламины, композиции, способы лечения и диагностики, способы идентификации соединения |
US5648541A (en) | 1995-09-28 | 1997-07-15 | Nps Pharmaceuticals, Inc. | Chiral reductions of imines leading to the syntheses of optically active amines |
CN1254465C (zh) | 1996-04-09 | 2006-05-03 | Nps医药公司 | 钙代谢化合物 |
JP4117506B2 (ja) | 1996-05-01 | 2008-07-16 | エヌピーエス ファーマシューティカルズ インコーポレイテッド | 無機イオン活性化合物 |
KR100860655B1 (ko) | 1996-07-08 | 2008-09-26 | 기린 파마 가부시끼가이샤 | 칼슘 수용체 활성 화합물 |
JP2002527414A (ja) | 1998-10-14 | 2002-08-27 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | 1,2−ジ置換シクロプロパン |
FR2809396B1 (fr) | 2000-05-24 | 2005-10-14 | Centre Nat Rech Scient | Nouvelles molecules possedant une activite calcimimetique et leur mode de preparation |
US7176322B2 (en) | 2002-05-23 | 2007-02-13 | Amgen Inc. | Calcium receptor modulating agents |
US6908935B2 (en) | 2002-05-23 | 2005-06-21 | Amgen Inc. | Calcium receptor modulating agents |
-
2004
- 2004-12-22 WO PCT/JP2004/019187 patent/WO2005065050A2/ja active Application Filing
- 2004-12-23 US US11/019,632 patent/US7582658B2/en not_active Expired - Fee Related
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH04501722A (ja) * | 1988-11-14 | 1992-03-26 | ジ・アップジョン・カンパニー | 抗―糖尿病、抗―肥満症および抗―アテローム性動脈硬化症薬として有用なα―アミノ―インドール―3―酢酸 |
JPH07506380A (ja) * | 1993-02-23 | 1995-07-13 | ブリガム・アンド・ウイミンズ・ホスピタル・インコーポレイテッド | カルシウム受容体活性化分子およびその関連物 |
Also Published As
Publication number | Publication date |
---|---|
US7582658B2 (en) | 2009-09-01 |
US20060069098A1 (en) | 2006-03-30 |
WO2005065050A2 (ja) | 2005-07-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2005065050A3 (ja) | 2環化合物 | |
EP1203768A4 (en) | ISOXAZOLINE DERIVATIVES AND HERBICIDES THAT CONTAIN IT AS AN ACTIVE INGREDIENT | |
CA2424600A1 (en) | Aliphatic nitrogenous five-membered ring compounds | |
MX9709951A (es) | Derivados de benzamida y su uso como antagonistas de vasopresina. | |
WO2003016286A1 (en) | 3-phenoxy-4-pyridazinol derivative and herbicide composition containing the same | |
HUP0300641A2 (hu) | Triazaspiro[5.5]undekán-származékok és hatóanyagként ezeket tartalmazó gyógyszerkészítmények | |
EP1702917A4 (en) | AMID DERIVATIVE AND MEDICINE | |
ES2187473T3 (es) | Triarylimidazoles. | |
EP1550662A4 (en) | NEW ADENINE COMPOUND AND ITS USE | |
CA2336412A1 (en) | Medicament for treatment of diabetes | |
WO2007033039A3 (en) | Proteasome inhibiting beta lactam compounds | |
EP1396493A4 (en) | HETEROCYCLIC COMPOUNDS | |
GEP20084284B (en) | Composition and antiviral activity of substituted azaindoleoxoacetic piperazine derivatives | |
HRP20070286T3 (en) | Substituted diketopiperazines and their use as oxytocyn antagonists | |
EP1243268A4 (en) | MEDICINAL COMPOSITION | |
EP1500652A4 (en) | DERIVATIVE AND MEDICINAL PRODUCT OF QUINAZOLINE | |
EP1314719A4 (en) | BENZOIC ACID DERIVATIVES AND MEDICAMENTS HAVING THE SAME AS ACTIVE INGREDIENT | |
WO2002024697A1 (fr) | Composes spiro et inhibiteurs de molecules d'adhesion contenant ces composes comme ingredient actif | |
EP1671957A4 (en) | THIADIAZOLINDERIVATE | |
EP1741714A4 (en) | HETEROCYLIC COMPOUND AND ANTI-MALIGNANT TUMOR AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT | |
YU44202A (sh) | Kvaternerne soli n-substituisanih cikiličnih ili ne- cikličnih amina kao farmaceutski preparati | |
WO2003031414A1 (fr) | Nouveau compose heterocyclique et agent anti-inflammatoire | |
EP1391452A4 (en) | 4-HYDROXPIPERIDIN DERIVATIVE ANALGETIC EFFECT | |
AR032230A1 (es) | Derivado sulfonamida conteniendo una composicion agricola y horticola | |
EP1593681A4 (en) | TRICYCLIC COMPOUND, PROCESS FOR THEIR PREPARATION AND USE |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A2 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
NENP | Non-entry into the national phase |
Ref country code: DE |
|
WWW | Wipo information: withdrawn in national office |
Country of ref document: DE |
|
NENP | Non-entry into the national phase |
Ref country code: JP |
|
WWW | Wipo information: withdrawn in national office |
Country of ref document: JP |
|
122 | Ep: pct application non-entry in european phase |