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WO2005057244A3 - Systeme de delivrance et de collecte de fibres optiques destine a des applications biologiques telles que le processus multiphotonique, spectroscopie et endoscopie - Google Patents

Systeme de delivrance et de collecte de fibres optiques destine a des applications biologiques telles que le processus multiphotonique, spectroscopie et endoscopie Download PDF

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Publication number
WO2005057244A3
WO2005057244A3 PCT/US2004/026521 US2004026521W WO2005057244A3 WO 2005057244 A3 WO2005057244 A3 WO 2005057244A3 US 2004026521 W US2004026521 W US 2004026521W WO 2005057244 A3 WO2005057244 A3 WO 2005057244A3
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WO
WIPO (PCT)
Prior art keywords
tissue
radiation
optical fiber
animal
plant
Prior art date
Application number
PCT/US2004/026521
Other languages
English (en)
Other versions
WO2005057244A2 (fr
Inventor
Alexander L Gaeta
Dimitre G Ouzounov
Watt W Webb
Rebecca M Williams
Warren R Zipfel
Original Assignee
Cornell Res Foundation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cornell Res Foundation Inc filed Critical Cornell Res Foundation Inc
Priority to EP04817749.7A priority Critical patent/EP1664854B1/fr
Priority to AU2004297876A priority patent/AU2004297876A1/en
Priority to JP2006523960A priority patent/JP4823906B2/ja
Priority to CA002535843A priority patent/CA2535843A1/fr
Publication of WO2005057244A2 publication Critical patent/WO2005057244A2/fr
Publication of WO2005057244A3 publication Critical patent/WO2005057244A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00163—Optical arrangements
    • A61B1/00165—Optical arrangements with light-conductive means, e.g. fibre optics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062—Arrangements for scanning

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Optics & Photonics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Endoscopes (AREA)

Abstract

La présente invention concerne un procédé permettant d'appliquer un rayonnement dans une fibre optique pour la détection d'une maladie dans une plante ou chez un animal ou autre tissu pénétrable, ou pour l'imagerie d'un tissu particulier d'une plante ou d'un animal. Une telle application de rayonnement dans une fibre optique permet également de détecter et de localiser des signaux de diffusion non linéaire et de fluorescence chez un sujet. Le rayonnement favorise efficacement une excitation multiphotonique simultanée. Les fibres optiques sont utilisées seules afin d'examiner des zones internes de tissus ; elles sont utilisées avec une aiguille de biopsie optique afin d'évaluer un tissu sub-superficiel ou avec un endoscope afin d'évaluer le tissu dans les cavités de l'organisme. La présente invention concerne également un dispositif permettant de coupler un rayonnement d'un laser verrouillé en mode ultracourt dans la voie du faisceau d'un microscope.
PCT/US2004/026521 2003-08-19 2004-08-16 Systeme de delivrance et de collecte de fibres optiques destine a des applications biologiques telles que le processus multiphotonique, spectroscopie et endoscopie WO2005057244A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP04817749.7A EP1664854B1 (fr) 2003-08-19 2004-08-16 Systeme de delivrance et de collecte de fibres optiques destine a des applications biologiques
AU2004297876A AU2004297876A1 (en) 2003-08-19 2004-08-16 Optical fiber delivery and collection system for biological applications such as multiphoton microscopy, spectroscopy, and endoscopy
JP2006523960A JP4823906B2 (ja) 2003-08-19 2004-08-16 多光子顕微鏡観察、分光法、および内視鏡観察などの生物学的用途のための光ファイバー送集光システム
CA002535843A CA2535843A1 (fr) 2003-08-19 2004-08-16 Systeme de delivrance et de collecte de fibres optiques destine a des applications biologiques telles que le processus multiphotonique, spectroscopie et endoscopie

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49624103P 2003-08-19 2003-08-19
US60/496,241 2003-08-19

Publications (2)

Publication Number Publication Date
WO2005057244A2 WO2005057244A2 (fr) 2005-06-23
WO2005057244A3 true WO2005057244A3 (fr) 2006-05-11

Family

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Family Applications (1)

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PCT/US2004/026521 WO2005057244A2 (fr) 2003-08-19 2004-08-16 Systeme de delivrance et de collecte de fibres optiques destine a des applications biologiques telles que le processus multiphotonique, spectroscopie et endoscopie

Country Status (6)

Country Link
US (1) US7702381B2 (fr)
EP (1) EP1664854B1 (fr)
JP (1) JP4823906B2 (fr)
AU (1) AU2004297876A1 (fr)
CA (1) CA2535843A1 (fr)
WO (1) WO2005057244A2 (fr)

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Also Published As

Publication number Publication date
CA2535843A1 (fr) 2005-06-23
EP1664854A2 (fr) 2006-06-07
WO2005057244A2 (fr) 2005-06-23
EP1664854A4 (fr) 2009-09-02
JP2007503851A (ja) 2007-03-01
US20050043636A1 (en) 2005-02-24
AU2004297876A1 (en) 2005-06-23
EP1664854B1 (fr) 2015-07-22
JP4823906B2 (ja) 2011-11-24
US7702381B2 (en) 2010-04-20

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