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WO2004011345A1 - Discharge member and container provided with the same - Google Patents

Discharge member and container provided with the same Download PDF

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Publication number
WO2004011345A1
WO2004011345A1 PCT/JP2003/009572 JP0309572W WO2004011345A1 WO 2004011345 A1 WO2004011345 A1 WO 2004011345A1 JP 0309572 W JP0309572 W JP 0309572W WO 2004011345 A1 WO2004011345 A1 WO 2004011345A1
Authority
WO
WIPO (PCT)
Prior art keywords
discharge
valve body
discharge hole
flow path
hole
Prior art date
Application number
PCT/JP2003/009572
Other languages
French (fr)
Japanese (ja)
Inventor
Yasushi Kawashiro
Yuji Sugahara
Original Assignee
Otsuka Pharmaceutical Co., Ltd.
Otsuka Techno Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co., Ltd., Otsuka Techno Corporation filed Critical Otsuka Pharmaceutical Co., Ltd.
Priority to EP03771397A priority Critical patent/EP1541487A1/en
Priority to CA002493365A priority patent/CA2493365A1/en
Priority to MXPA05001236A priority patent/MXPA05001236A/en
Priority to JP2005505577A priority patent/JPWO2004011345A1/en
Priority to BR0313111-4A priority patent/BR0313111A/en
Priority to US10/522,800 priority patent/US20060043116A1/en
Priority to AU2003248136A priority patent/AU2003248136A1/en
Publication of WO2004011345A1 publication Critical patent/WO2004011345A1/en
Priority to HK06100075.2A priority patent/HK1083210B/en

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D47/00Closures with filling and discharging, or with discharging, devices
    • B65D47/04Closures with discharging devices other than pumps
    • B65D47/06Closures with discharging devices other than pumps with pouring spouts or tubes; with discharge nozzles or passages
    • B65D47/18Closures with discharging devices other than pumps with pouring spouts or tubes; with discharge nozzles or passages for discharging drops; Droppers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00Closures not otherwise provided for
    • B65D51/16Closures not otherwise provided for with means for venting air or gas
    • B65D51/1605Closures not otherwise provided for with means for venting air or gas whereby the interior of the container is maintained in permanent gaseous communication with the exterior
    • B65D51/1616Closures not otherwise provided for with means for venting air or gas whereby the interior of the container is maintained in permanent gaseous communication with the exterior by means of a filter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D47/00Closures with filling and discharging, or with discharging, devices
    • B65D47/04Closures with discharging devices other than pumps
    • B65D47/20Closures with discharging devices other than pumps comprising hand-operated members for controlling discharge
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D47/00Closures with filling and discharging, or with discharging, devices
    • B65D47/04Closures with discharging devices other than pumps
    • B65D47/20Closures with discharging devices other than pumps comprising hand-operated members for controlling discharge
    • B65D47/2018Closures with discharging devices other than pumps comprising hand-operated members for controlling discharge comprising a valve or like element which is opened or closed by deformation of the container or closure
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D47/00Closures with filling and discharging, or with discharging, devices
    • B65D47/04Closures with discharging devices other than pumps
    • B65D47/20Closures with discharging devices other than pumps comprising hand-operated members for controlling discharge
    • B65D47/2018Closures with discharging devices other than pumps comprising hand-operated members for controlling discharge comprising a valve or like element which is opened or closed by deformation of the container or closure
    • B65D47/2056Closures with discharging devices other than pumps comprising hand-operated members for controlling discharge comprising a valve or like element which is opened or closed by deformation of the container or closure lift valve type
    • B65D47/2062Closures with discharging devices other than pumps comprising hand-operated members for controlling discharge comprising a valve or like element which is opened or closed by deformation of the container or closure lift valve type in which the deformation raises or lowers the valve stem
    • B65D47/2068Closures with discharging devices other than pumps comprising hand-operated members for controlling discharge comprising a valve or like element which is opened or closed by deformation of the container or closure lift valve type in which the deformation raises or lowers the valve stem in which the stem is lowered by the pressure of the contents and thereby opening the valve
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D47/00Closures with filling and discharging, or with discharging, devices
    • B65D47/04Closures with discharging devices other than pumps
    • B65D47/20Closures with discharging devices other than pumps comprising hand-operated members for controlling discharge
    • B65D47/2018Closures with discharging devices other than pumps comprising hand-operated members for controlling discharge comprising a valve or like element which is opened or closed by deformation of the container or closure
    • B65D47/2056Closures with discharging devices other than pumps comprising hand-operated members for controlling discharge comprising a valve or like element which is opened or closed by deformation of the container or closure lift valve type
    • B65D47/2062Closures with discharging devices other than pumps comprising hand-operated members for controlling discharge comprising a valve or like element which is opened or closed by deformation of the container or closure lift valve type in which the deformation raises or lowers the valve stem
    • B65D47/2075Closures with discharging devices other than pumps comprising hand-operated members for controlling discharge comprising a valve or like element which is opened or closed by deformation of the container or closure lift valve type in which the deformation raises or lowers the valve stem in which the stem is raised by the pressure of the contents and thereby opening the valve
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00Closures not otherwise provided for
    • B65D51/16Closures not otherwise provided for with means for venting air or gas

Definitions

  • the present invention relates to a discharge member for discharging a liquid content filled in a flexible container by pressing the container, and a container provided with the discharge member.
  • a discharge member 150 shown in FIGS. 41A and 41B is used in a container such as an eye drop container that is used by dripping the content liquid.
  • This discharge member 150 is attached to the mouth part 152 a of the container body 152, and the inner diameter of the discharge hole 151 is formed by discharging the content liquid by pressing the container body 152. It is set so that the content liquid is not discharged when the container body 15 2 is not pressed, and the diameter of the discharge port 15 3 It is set to a size that can be held in the state.
  • FIGS. 42 (a) and (b) As shown in, there is a risk that microorganisms, dust, etc. attached to the discharge port 1553 may flow back into the container body 152 together with the content liquid (ophthalmic solution) 1555 remaining at the discharge port 1553.
  • reference numeral 156 indicates a bubble in the content liquid (ophthalmic solution) 155.
  • microorganisms, dust, etc. enter the inside of the container body, it may cause decay or deterioration of the liquid content.
  • benzalkonium chloride, parabens, etc. as preservatives, are incorporated in the ophthalmic solution contained in the ophthalmic container. Have been.
  • Japanese Patent Application Laid-Open No. 2002-80055 describes a discharge container with a filter that employs a so-called delaminated bottle that includes an outer layer and an inner layer that is provided on the inner surface so as to be peelable. Have been.
  • this discharge container even after the discharge of the content liquid, it is possible to prevent outside air from flowing into the container from the discharge port, so that it is possible to prevent bacteria from being mixed into the content liquid.
  • it in order to cope with a change in the internal pressure of the container due to the discharge of the content liquid, it is necessary to provide an easily deformable inner container composed of the above-mentioned inner layer, and there is a problem that the manufacturing cost of the container increases.
  • Japanese Patent Application Laid-Open No. 2000-017-1709 Japan
  • Japanese Patent Application Laid-Open No. 201001-2064 It describes an antibacterial container in which a porous filter, which is not capable of passing dust and the like, is disposed at a discharge port.
  • the porous filter is dried in a state in which the chemical solution or the like is impregnated, the filter may be clogged by a solute in the chemical solution.
  • the ophthalmic solution may be a suspension depending on the application, and in such a case, the problem of clogging is more likely to occur.
  • a metal filter is used as a porous filter.
  • a sintered body or a resin sintered body is used, but in this case, there is a possibility that the fine particles of the sintered body are mixed with the chemical solution and discharged from the container. Disclosure of the invention
  • an object of the present invention is to provide a member at the mouth of a container for discharging the liquid content as droplets, to prevent backflow of the internal solution, and to allow air to flow into the container after the discharging operation.
  • Another object of the present invention is to eliminate or suppress the compounding of a chemical for preventing decay or deterioration of the content liquid, and to discharge the liquid even if the content liquid is a suspension.
  • An object of the present invention is to provide a container capable of realizing a smooth discharge without causing clogging at an outlet.
  • a discharge member according to the present invention for solving the above-mentioned problems has a bottomed substantially cylindrical or bowl-shaped discharge portion having a discharge hole at a bottom portion, and the discharge hole side is defined as a downstream side. Closes the discharge hole and Z or the flow path in the discharge part connected to the discharge hole without receiving the hydraulic pressure, and deforms when receiving the hydraulic pressure from the upstream to deform the discharge hole and / or the flow path.
  • a valve body made of an elastic body, and a ventilation hole connected to a flow path on the upstream side of the valve body via a ventilation filter. And the opening of the discharge hole and / or the flow path is not achieved by an external ventilation pressure to the ventilation filter.
  • the valve body that controls the closing and opening of the discharge hole and the flow path is made of an elastic body, and is configured to receive the discharge hole and / or the flow while receiving no hydraulic pressure from the upstream side.
  • the passage is closed, and when receiving hydraulic pressure from the upstream side, it deforms and opens the discharge hole and / or the flow passage.
  • the discharge holes and Z or the flow path are opened, the discharge hole and the upstream side of the discharge portion (specifically, a container body such as an eye drop container connected to the discharge member of the present invention) are formed. By communicating with each other, discharge of a chemical solution or the like from the discharge hole can be realized.
  • pressure may be applied to a container body such as an eye drop container connected to the discharge member.
  • the liquid pressure of the content liquid (chemical solution, etc.) is applied to the valve body of the discharge member from the upstream side, whereby the valve body is deformed and the discharge hole and / or the flow path is formed. Be released.
  • the deformed container body tries to flow outside air from the ventilation holes in order to restore its shape.
  • the vent hole communicating with the flow path of the content liquid is provided. Since the ventilation filter is provided, inflow of air into the container after the discharging operation can be aseptically achieved.
  • the negative pressure generated inside the container body connected to the discharge member for allowing the outside air to flow has an effect of accelerating the restoration operation of the deformed valve element. Therefore, the gap (flow path) formed between the valve element and the discharge part by performing the discharge operation is immediately closed by removing the pressurization to the container body, and the present invention
  • the valve element in the discharge member acts as a check valve.
  • Embodiments of the ejection member according to the present invention include, for example, first to fifth embodiments described below.
  • the first discharge member includes a bottomed substantially cylindrical or bowl-shaped discharge portion having a discharge hole at a bottom portion, and a discharge portion disposed in the discharge portion, wherein the discharge hole side is a downstream side.
  • a valve body made of an elastic body, which closes the discharge hole in a state where the discharge pressure is not received from the upstream side, and is compressed and deformed to open the discharge hole when receiving the hydraulic pressure from the upstream side;
  • a locking section disposed inside the section and defining a flow path between the inner surface of the discharge section and fixing the valve element on the upstream side; and a flow path on the upstream side of the valve element via a ventilation filter.
  • a connecting vent wherein the compression deformation of the valve body is achieved by a fluid pressure lower than the fluid pressure of the vent filter, and the opening of the discharge port and / or the flow path is provided to the vent filter. It cannot be achieved by external ventilation pressure. I do.
  • the valve body made of an elastic body disposed inside the discharge section controls closing and opening of the flow path using the discharge hole as a valve seat.
  • This valve element closes the discharge hole in a state where it is not receiving the hydraulic pressure from the upstream side, and when it receives the hydraulic pressure from the upstream side, it compressively deforms to open the discharge hole.
  • the discharge hole communicates with the flow path defined between the inner surface of the discharge portion and the locking portion, thereby realizing discharge of a chemical solution or the like from the discharge portion. can do.
  • pressure may be applied to the container body connected to the discharge member in the same manner as described above.
  • the discharge process and the discharge process can be performed while preventing the liquid discharged from the discharge hole from flowing backward and the microorganisms and dust accompanying the discharge from entering the upstream side to a high degree. Restoration of the container after operation can be performed smoothly.
  • valve body and the locking portion are integrally formed.
  • the production process of the discharge member can be made more efficient.
  • a method of integrally molding the valve body and the locking portion for example, multicolor molding insert molding is used.
  • the second discharge member includes a bottomed substantially cylindrical or bowl-shaped discharge portion having a discharge hole at a bottom portion, a valve seat fixed in the discharge portion, and an inner surface of the discharge portion.
  • a valve body made of an elastic body disposed inside the discharge part is paired with a valve seat part also disposed inside the discharge part to close and open the flow passage. Control. The valve body abuts on the valve seat without receiving the hydraulic pressure from the upstream side, and closes a flow path connecting the discharge hole and the upstream side of the discharge portion.
  • the second discharge member in order to discharge a chemical solution or the like from the discharge holes, pressure may be applied to the container body connected to the discharge member, as described above.
  • the air can be aseptically introduced from the ventilation filter, and the restoration operation of the valve that has been deformed by the negative pressure that tries to allow the outside air to be accelerated ( Therefore, the fact that the valve body can act as a check valve) is the same as in the case described above.
  • the second discharge member since the compression deformation of the valve body is achieved by a liquid pressure lower than the liquid pressure of the ventilation filter, liquid leakage does not occur in the ventilation hole during the discharge operation.
  • the discharge hole is used instead of the ventilation hole when the container body is restored. There is no possibility that outside air flows in from the outlet or the contents liquid leaks out of the discharge holes.
  • the discharge process and discharge can be performed while preventing the liquid discharged from the discharge holes from flowing backward and invading microorganisms and dust to the upstream side. Restoration of the container after operation can be performed smoothly.
  • the valve body is fixed to the inner surface of the discharge part from the viewpoint of strictly closing and opening the flow path. Therefore, although not limited thereto, it is preferable that the valve body and the discharge portion are formed by integral molding. By integrally molding the valve body and the locking part, both are securely fixed and
  • valve body and discharge section are integrated 3 009572
  • multicolor molding insert molding can be mentioned.
  • a third discharge member includes a bottomed substantially cylindrical or bowl-shaped discharge portion having a discharge hole at a bottom portion, and a discharge portion disposed in the discharge portion, wherein the discharge hole side is a downstream side. Elasticity that closes the discharge hole or the flow path leading to the discharge hole without receiving the hydraulic pressure from the upstream side, and expands and deforms to open the discharge hole or the flow path when receiving the hydraulic pressure from the upstream side.
  • a valve body comprising: a valve body; and a ventilation hole connected to a flow path upstream of the valve body via a ventilation filter, wherein the expansion deformation of the valve body is smaller than the hydraulic pressure of the ventilation filter. Pressure, and the opening of the discharge hole or the flow path is not achieved by an external ventilation pressure to the ventilation filter.
  • an elastic body disposed inside the discharge portion controls the closing and opening of the discharge hole or the flow path.
  • This valve element closes the discharge hole or the flow path leading to the discharge hole without receiving the hydraulic pressure from the upstream side, and when receiving the hydraulic pressure from the upstream side, it expands and deforms, and the discharge hole or the flow path is closed. Open. As a result of the opening of the discharge hole or the flow path, the flow path between the upstream side of the valve body and the discharge hole is communicated, so that the discharge of the chemical solution or the like from the discharge hole can be realized.
  • the third discharge member in order to realize the discharge of the chemical solution or the like from the discharge holes, pressure may be applied to the container body connected to the discharge member, as described above.
  • the valve When the valve is restored after the discharge operation, the air can be aseptically introduced from the ventilation filter, and the restoration operation of the valve that has been deformed by the negative pressure that tries to allow the outside air to be accelerated ( Therefore, the fact that the valve body can act as a check valve) is the same as in the case described above.
  • the expansion deformation of the valve body is achieved by a liquid pressure lower than the liquid pressure of the ventilation filter, liquid leakage does not occur in the ventilation hole during the discharge operation.
  • such extension deformation is not caused by external pressure (thus, even if a pressure equivalent to the ventilation pressure of the ventilation filter is applied from the outside, the extension deformation is not achieved).
  • the discharge processing is performed while preventing the liquid discharged from the discharge holes from flowing backward and invading microorganisms, dust and the like to the upstream side at a high level. And the restoration of the container after the discharge operation can be performed smoothly.
  • the valve body has a valve body fixed in the flow path and a protrusion at the discharge hole side end, and the protrusion at the valve body end is It engages with a ridge provided on the inner wall of the flow path connected to the discharge hole from the downstream side to close the flow path, and
  • the valve body extends and deforms from the upstream side to the downstream side by hydraulic pressure to form a gap between the projection at the tip of the valve body and the ridge on the inner wall of the flow passage.
  • the projection at the tip of the valve body portion of the valve body is engaged with the ridge provided on the inner wall of the flow path from the downstream side without receiving the hydraulic pressure, and the flow path is closed.
  • the valve element receives the hydraulic pressure, it expands and deforms downstream from the engagement position, so that the flow path is opened between the projection at the end of the valve main body and the projection on the inner wall of the flow path. Is done.
  • the projection at the tip of the valve body returns to the upstream side due to the restoration of the valve body, so it re-engages with the ridge on the inner wall of the flow passage Then, the flow path is closed.
  • the restoration operation of the valve body is accelerated by the negative pressure for introducing outside air, which is generated when the container body deformed by the discharge operation is restored.
  • the fourth discharge member according to the present invention is configured such that the fourth discharge member abuts from the outer surface side of the bottom substantially cylindrical or bowl-shaped discharge portion having a discharge hole at the bottom, and flows down the discharge hole side.
  • a valve body made of an elastic body that closes the discharge hole in a state where it is not receiving the hydraulic pressure from the upstream side when receiving the hydraulic pressure from the upstream side, and expands and deforms to open the discharge hole when receiving the hydraulic pressure from the upstream side.
  • a ventilation hole connected to the discharge hole via a ventilation filter, wherein a hydraulic pressure in which the expansion deformation of the valve body is smaller than the hydraulic pressure of the ventilation filter And the opening of the discharge hole is not achieved by an external ventilation pressure to the ventilation filter.
  • a valve body made of an elastic body that comes into contact with the discharge hole from the outer surface side of the discharge part controls closing and opening of the discharge hole.
  • This valve body closes the discharge hole in a state where it is not receiving the hydraulic pressure from the upstream side, and when it receives the hydraulic pressure from the upstream side, it expands and deforms outside the discharge part (downstream side) (as a result, the valve body Radiate to the outside of the discharge section) to open the discharge hole.
  • the opening of the discharge hole the flow path between the upstream side of the valve body and the discharge hole communicates, and the discharge of the chemical solution or the like from the discharge hole can be realized.
  • the fourth discharge member in order to realize the discharge of the chemical solution or the like from the discharge holes, similarly as described above, pressure may be applied to the container body connected to the discharge member.
  • the valve When the valve is restored after the end of the discharge operation, the air can be aseptically introduced from the ventilation filter, and the restoration operation of the valve that has been deformed by the negative pressure that tries to let in the outside air is accelerated.
  • the valve element can be made to act as a check valve
  • the expansion deformation of the valve body since the expansion deformation of the valve body is achieved by the liquid pressure lower than the liquid pressure of the ventilation filter, the liquid may leak to the ventilation hole during the discharge operation. There is no. Moreover, such an expansion deformation does not occur due to an external pressure due to the structure of the valve body (thus, even if a pressure equivalent to the ventilation pressure of the ventilation filter is applied from the outside, the expansion deformation is not achieved). When the container body is restored, no outside air flows through the discharge hole instead of the vent hole, and accordingly, the content liquid does not leak from the discharge hole.
  • the discharge process and the discharge process can be performed while preventing the backflow of the liquid discharged from the discharge hole and the accompanying invasion of microorganisms and dust to the upstream side. Restoration of the container after operation can be performed smoothly.
  • the discharge hole is defined by a substantially disk-shaped valve seat fixed in the discharge portion and a discharge portion inner wall surface that holds the valve seat.
  • the valve element has a substantially annular thin portion and The thin portion is brought into contact with the valve seat from the outer surface side of the discharge portion to close the discharge hole, and the thin portion of the valve body is driven by hydraulic pressure when the discharge hole side is downstream. Then, it is preferable that the discharge hole is expanded and deformed downstream to open the discharge hole. In this case, the discharge hole of the valve body is closed by contacting a thin portion of the valve body with a substantially disk-shaped valve seat in a state where the valve body is not subjected to hydraulic pressure.
  • the valve element expands and deforms downstream when receiving the hydraulic pressure (radiates outward from the discharge portion), and is partitioned between the substantially disc-shaped valve seat and the inner wall surface of the discharge portion holding the valve seat. Discharge holes are opened. After the discharge operation is completed and the hydraulic pressure is no longer applied to the valve element, the flow path is closed because the thin portion of the valve element again contacts the substantially disk-shaped valve seat. As described above, the restoration operation of the valve body is accelerated by the negative pressure for introducing outside air, which is generated when the container body deformed by the discharge operation is restored.
  • the valve body is formed integrally with the outside of the discharge part. In this case, the production of the discharge member can be performed efficiently.
  • the method of integrally molding the valve body and the discharge portion is not particularly limited, and various methods such as multicolor molding and insert molding can be adopted.
  • a fifth discharge member includes a substantially cylindrical bottomed or substantially bowl-shaped discharge portion having a hole at the bottom, a substantially annular valve body, and a substantially annular thin portion provided at the tip thereof.
  • a valve body made of an elastic body, wherein the valve body portion is fixed in the discharge portion while the thin portion is exposed to the outside of the discharge portion from the hole, and the valve is disposed in the discharge portion, and the valve is disposed in the discharge portion.
  • a cylindrical valve body support portion that defines a discharge hole together with a body, and a flow passage that is connected to a flow path upstream of the valve body through a ventilation filter when the discharge hole side is a downstream side.
  • the valve body is closed to the outer peripheral surface of the valve body supporting portion while the night time pressure is not received from the upstream side, and the discharge hole is closed.
  • the thin portion is stretched and deformed to open the discharge hole. And the opening of the discharge hole is not achieved by an external ventilation pressure to the ventilation filter.
  • the valve body made of an elastic body disposed inside the discharge part is fixed in a state where its thin portion is exposed to the outside of the discharge part from a hole provided at the bottom of the discharge part, A discharge hole is defined between the valve body support member and the valve body support member.
  • the thin-walled portion controls closing and opening of the discharge hole by using the cylindrical valve body support portion of the valve body support member as a valve seat. That is, the thin-walled portion of the valve body contacts the outer peripheral surface of the valve body support portion without receiving the hydraulic pressure from the upstream side, thereby closing the discharge hole.
  • the thin portion undergoes extension deformation outside the discharge portion (downstream side) (as a result, the valve element radially extends to the outer peripheral side of the valve element support portion), As a result, the discharge hole is opened. As a result of the opening of the discharge hole, the flow path between the upstream side of the valve body and the discharge hole communicates, and the discharge of a chemical solution or the like from the discharge hole can be realized.
  • the fifth discharge member in order to discharge a chemical solution or the like from the discharge holes, pressure may be applied to the container body connected to the discharge member in the same manner as described above.
  • the valve When the valve is restored after the discharge operation, the air can be aseptically introduced from the ventilation filter, and the restoration operation of the valve that has been deformed by the negative pressure that tries to allow the outside air to be accelerated ( Therefore, the fact that the valve body can act as a check valve) is the same as in the case described above.
  • the expansion deformation of the valve body is achieved by a liquid pressure lower than the liquid pressure of the ventilation filter, liquid leakage does not occur in the ventilation hole during the discharge operation. Moreover, such an expansion deformation does not occur due to an external pressure due to the structure of the valve body (thus, even if a pressure equivalent to the ventilation pressure of the ventilation filter is applied from the outside, the expansion deformation is not achieved).
  • the container body is restored, no outside air flows through the discharge hole instead of the vent hole, and accordingly, the content liquid does not leak from the discharge hole.
  • the discharge processing and the discharge are performed while preventing the liquid discharged from the discharge hole from flowing backward and the microorganisms and dust accompanying the discharge from entering the upstream side to a high degree. Restoration of the container after the operation can be performed smoothly.
  • the valve body supporting portion has a flange on the upstream side of the cylindrical portion, and the valve body of the valve body is not subjected to the hydraulic pressure. It is preferable that the flow path is closed by abutting on the above-mentioned flange portion, and that the flow path is opened between the valve body support portion and a compressive deformation when subjected to hydraulic pressure. .
  • valve body in a state where the valve body is not receiving the hydraulic pressure from the upstream side, not only is the thin portion abutted on the outer peripheral surface of the valve body support portion to close the discharge hole, but also the valve body portion is closed.
  • the channel is closed by making contact with the flange of the valve body support. Therefore, the discharge hole can be more reliably closed.
  • the valve element receives hydraulic pressure from the upstream side, not only does the thin wall portion expand and deform outside the discharge section (downstream side), but also the valve body section is compressed and deformed, and the valve element is compressed and deformed. A flow path is formed (opened) with the flange of the support.
  • the discharge hole and the flow path are opened, so that the flow path between the upstream side of the valve body and the discharge hole communicates with each other, so that the discharge of the chemical solution or the like from the discharge hole can be realized.
  • the restoring operation after the discharge operation is completed and the liquid pressure is not applied to the valve body restores the container body deformed by the discharge operation as described above. It is accelerated by the negative pressure that is introduced when introducing outside air.
  • the valve body of the valve body is formed so as to be integrated with the inner surface of the discharge part. In this case, the production of the discharge member can be performed efficiently.
  • the method of integrally molding the valve body and the discharge portion is not particularly limited, and various methods such as multicolor molding insert molding can be employed.
  • the valve body and / or the discharge hole have been subjected to antibacterial treatment.
  • antibacterial treatment is applied to the valve body and / or the discharge port, it exerts an effect of preventing the growth of bacteria and the like against the content liquid (residual liquid) staying near the discharge port after the end of the discharge operation. be able to.
  • the target of the antibacterial treatment may be appropriately selected according to the configuration of the discharge member.
  • Various types such as the whole, valve seat, container body, the surface of the cap that covers the discharge part (particularly the inner surface that comes into contact with the discharge part), and the water-absorbing material (sponge, cloth, paper, hydrogel, etc.) placed inside the cap
  • the site is not particularly limited.
  • the antibacterial treatment includes, for example, an elastic material such as a thermoplastic elastomer that forms a valve body; a resin material for forming a discharge portion, a discharge hole, a valve seat, and the like; a preservative, A drug such as an antibacterial agent is blended, the above-mentioned drug is adhered to the surface of a preformed valve body or a discharge portion by coating or the like, or is absorbed in a valve body, a discharge portion, a cap, or a cap.
  • This can be achieved by subjecting a material such as a material to a surface treatment such as silane coupling / selenium coating.
  • Antimicrobial treatment can be applied to the hydrogel, which is a combination of a polymer such as (meth) acrylamide and a water-swellable clay mineral, by coating the surface with selenium.
  • the discharge member according to the present invention is preferably provided with a liquid passage filter upstream of the discharge hole or upstream of the opening / closing position of the flow path by the valve element. Even if a situation in which microorganisms, dust and the like enter the liquid remaining in the vicinity of the discharge port of the discharge part due to the provision of the liquid passage filter occurs, the residual liquid is connected to the discharge member. In the event of intrusion (backflow) into the main body, this can be suppressed or prevented. That is, providing a liquid passage filter is preferable from the viewpoint of suppressing or preventing intrusion of contaminants into a container or the like connected to the discharge member.
  • the liquid passage filter has a pore diameter of, for example, about 0.2 to 0.45 / m (small pore diameter), it is difficult to apply the discharge member of the present invention to a container containing a suspension. become. On the other hand, even in the event that a residual liquid containing microorganisms, dust, and the like flows back from the discharge hole, the residual liquid enters the container body connected to the discharge member of the present invention (backflow). ) Can be reliably prevented or suppressed.
  • the filter has a pore size of, for example, about 10 to 20 ⁇ (with a relatively large pore size) 3 009572
  • the discharge member of the present invention can be applied to a container for storing the suspension.
  • a new effect of suppressing the components of the suspension from settling near the discharge port can be obtained.
  • the passage of microorganisms and the like can be suppressed to some extent, so that a residual liquid containing microorganisms and the like may flow backward from the discharge hole. Even if this is the case, a certain effect can be obtained in suppressing the situation where the residual liquid enters (backflows) into the container body.
  • a container of the present invention for solving the above-mentioned problems is provided with a discharge member according to the present invention at an opening of a container body.
  • the container of the present invention is suitable, for example, as an ophthalmic container for storing an ophthalmic solution.
  • the first discharge member 10 includes a bottomed substantially cylindrical (or substantially bowl-shaped) discharge portion 11 having a discharge hole 12 at the bottom, and a discharge portion.
  • a valve element that is disposed inside 1 and closes the discharge port 12 when it is not receiving hydraulic pressure from the upstream side U, and compresses and deforms when it receives hydraulic pressure from the upstream side U to open the discharge port 12.
  • a locking portion 1 4 that defines a flow path 15 between 13 and an inner surface 1 1 d of the discharging portion that is disposed inside the discharging portion 11 and that fixes the valve element 13 on the upstream side U.
  • a ventilation hole 16 connected to a flow path on the upstream side of the valve body 13 via the ventilation filter 17.
  • the discharge hole 12 is normally closed by the valve 13, but when hydraulic pressure is applied to the valve 13 from the upstream side U through the flow path 15, the valve 13 is compressed and deformed. As a result, a gap is generated between the discharge hole 12 of the discharge portion 11 and the valve body 13. This allows the content liquid to be discharged through the gap.
  • the valve body 13 is fixed in the discharge member 10 by a locking portion 14, and between the locking portion 14 and the inner surface 11 d of the discharge portion, a flow path 15 of a chemical solution or the like is formed. Has become. Since the discharge section 11 needs to be provided with the ventilation filter 17 in the ventilation hole 16, the discharge section main body 11 a having the discharge hole 12 and the upstream section U are provided at the mouth of a chemical solution container or the like. It is made up of two members, the connecting part 1 1b to be connected. The discharge portion main body 11a and the connecting portion 11b are integrated by a joining means such as ultrasonic bonding with the ventilation filter 17 sandwiched between the connecting portions 11c.
  • the first discharge member 10 is used by being attached to the mouth of the container body 21 as shown in FIG. 2, for example.
  • the discharge member 10 is attached to the neck 22 of the container 20 via the inner plug 23.
  • the inner plug 23 is slidably inserted into the neck 22 of the container 20 as shown in FIGS. 2 and 3, and
  • FIG. 2 is a cross-sectional view of the container 20 in use.
  • FIG. 3 shows a sectional view of the container 20 in an unopened state.
  • the discharge member 10 is in a state of being shallowly fitted to the container body 21. Further, in this state, the distal end portion 23 a of the inner plug 23 is in contact with the flange 19 provided on the inner surface of the discharge member 10. As a result, the flow path 15 of the discharge member 10 is divided by the flange 19 and the distal end portion 23 a of the inner plug 23, and there is no empty liquid contained in the container body 21. It can maintain the bacterial state at a higher level and prevent the deterioration of the content liquid (air oxidation, etc.).
  • FIGS. 4 and 5 show a series of steps of the discharging operation using the first discharging member according to the present invention and the container provided with the first discharging member.
  • FIG. 4 (a) shows a state in which no pressure is applied to the container body 21. In this state, the valve 13 of the discharge member closes the discharge hole 12. Therefore, the content liquid 24 stored in the container body 21 is not discharged from the discharge part 11 and stays in the container body 21 and the discharge member.
  • FIG. 4B shows a state where pressure is applied to the container body 21. In this state, the liquid pressure of the content liquid 24 is applied to the valve body 13 of the discharge member from the upstream side U. Thus, since the valve element 13 is compressed and deformed, the discharge hole 12 is opened, and the content liquid 24 is discharged as a droplet 25.
  • FIG. 5 (a) is a continuation of the state shown in FIG. 4 (b), and shows a state in which pressurization of the container body 21 is stopped.
  • the valve body 13 of the discharge member is no longer subjected to the liquid pressure due to the content liquid 24, and the valve body 13 is restored to the shape before pressurization, and the discharge hole 12 is closed again. Is done.
  • FIG. 5 (b) is a continuation of the state shown in FIG. 5 (a).
  • the container main body 21 tries to restore the shape before pressurization. Is shown.
  • the valve member 13 of the discharge member closes the discharge hole 12, so that the outside air flows into the container body 21 exclusively through the vent hole 16.
  • a liquid filter 18 is provided on a flow path 15 connected to the discharge hole 12. Is provided. Therefore, as described above, even in the event that a residual liquid containing microorganisms, dust, and the like flows back from the discharge port 12, the residual liquid is connected to the discharge member 10 ′. It is possible to suppress or prevent intrusion (backflow) up to 1.
  • the valve bodies 13a and 13b may have a cross-sectional shape as shown in FIG. 7 and FIG. That is, as in the discharge member 10a shown in FIG. 7, the tip of the valve body 13a exposed at the discharge hole 12 may be flat, and the discharge member 10b shown in FIG. As shown in the above, the valve body 13b may have a depression 13c at its tip.
  • the valve element 13 b having the shape shown in FIG. 8 is not provided with the depression a 3 c when receiving the hydraulic pressure from the upstream U side (the valve elements 13 and 13 shown in FIGS. 1 and 7).
  • the second discharge member 30 has, as shown in, for example, FIG. 9 (cross-sectional view) and FIG. Part 31, a ring-shaped valve element 33 disposed inside the discharge part 31, and an opening end 31 d of the discharge part 31 1.
  • the valve seat 34 that contacts the upstream side U of the valve body 33 when it is set to the side D, and the vent hole that connects to the flow path 35 on the upstream side U of the valve body 33 via the ventilation filter 37 3 and 6.
  • the discharge section 31 needs to be provided with the ventilation filter 37 in the ventilation hole 36, the discharge section main body 31a provided with the discharge hole 32 and the discharge section 31 disposed at the upstream side U and at the mouth of a chemical solution container or the like. It is composed of two members, a connecting portion 31b to be connected.
  • the discharge unit main body 3 1a and the connecting part 3 1b are integrated by a bonding means such as ultrasonic bonding with the ventilation filter 37 sandwiched between the flanges 31 f (connection part 31 c). .
  • the integrally molded product of the discharge portion main body 31 a and the valve body 33 is a ring-shaped valve body as shown in a plan view in FIG. 11. 33 is brought into close contact with at least a part of the inner surface 31e of the discharge portion main body 31a.
  • a portion indicated by a dotted line with reference numeral 36 indicates a ventilation hole covered with a ventilation filter 37.
  • FIG. 11 (b) is a bottom view showing an integrally formed product of the discharge portion main body 31a and the valve body 33.
  • Holes (injection holes) 31 g are provided in the discharge portion main body 31a shown in FIG.
  • the discharge unit main body 31 a can be molded by, for example, injecting a resin for forming the discharge unit main body 31 a into a mold. After the injection, the opening end 31 d side of the discharge unit 31 is formed.
  • the mold movable mold
  • the protrusion main body 31a and the valve body 33 can be manufactured by integral molding. In the case where the valve element 33 is injected from the opening end 31 d side of the discharge part to be integrally molded, the injection hole 31 g is not necessary.
  • valve seat portion 34 fitted into the discharge portion main body 31a from the upstream side U is shown in FIG.
  • a cylinder 34c having a flange 34d and a flange of the cylinder 34c are provided.
  • a valve seat 34a arranged so as to close the opening on the side opposite to the flange 34d side.
  • the portion indicated by the reference numeral 34b is a portion that partitions the flow path 35 for the chemical solution or the like together with the hollow portion of the ring-shaped valve body 33.
  • the portion indicated by the reference numeral 34 e is a connecting portion between the cylinder 34 c and the valve seat 34 a.
  • the valve body 33 has a ring shape.
  • the valve body is not limited to the one that is continuous (ring-shaped) in the circumferential direction X of the discharge part main body 31a.
  • the valve seat (not shown) and the discharge unit body 3 la ' are connected with the compression deformation of the valve body 33'.
  • the area of the flow path (not shown) generated between them becomes narrower than when the valve element 33 is ring-shaped (FIG. 11). Therefore, the shape of the valve element may be appropriately set according to the width of the flow path region required for the discharge member.
  • reference numeral 3 1 e 5 shows the inner surface of the ejection detecting portion main body 3 1 a
  • FIG. 13 (b) shows a valve seat 34 used for a discharge member provided with a valve element 33 ′ having the shape shown in FIG. 13 (a).
  • the flow path 35 of the valve seat 3 4 ′ may be provided in accordance with the shape of the valve element 3 3 ′ of the discharge member shown in FIG. 13A.
  • reference numeral 34a denotes a valve seat.
  • the second discharge member 30 is used by being attached to the mouth of the container body 41, for example, as shown in FIG.
  • FIG. 15 and FIG. 16 show a series of steps of the discharging operation using the second discharging member and the container having the same according to the present invention.
  • FIG. 15A shows a state in which no pressure is applied to the container body 41. In this state, the valve element 33 is closed between the flow path 35 on the discharge section main body 3 1a side and the flow path 35 on the connection section 3 1b side, and the discharge hole 32 and the container body 4 are closed. Communication with 1 has been interrupted. Therefore, the content liquid 44 stored in the container body 41 is not discharged from the discharge part 31 and stays in the container body 41 and the discharge member 30.
  • FIG. 15 (b) shows a state in which pressure is applied to the container body 41.
  • valve element 33 receives the hydraulic pressure from the upstream side U through the flow path 35, and the hydraulic pressure causes compression deformation. Therefore, valve element 3 There is a gap between the valve body 3 and the valve seat 3 4a (the valve body 33 is opened), and the flow path 35 on the discharge body 3 1a side and the flow path 3 on the connection part 3 1b side 3 Communication with 5 is established. As a result, the content liquid 44 stored in the container body 41 is discharged from the discharge unit 31 as a droplet 45.
  • FIG. 16 (a) is a continuation of the state shown in FIG. 15 (b), and shows a state in which pressurization of the container body 41 is stopped.
  • the valve element 33 is restored to the shape before pressurization, and the valve element 33 and the valve are again formed.
  • the seat between the seats 3 4a is closed.
  • Fig. 16 (b) is a continuation of the state shown in Fig. 16 (a).
  • FIGS. 14 and 17 the inner plug 43 is fitted into the neck 42 of the container 40.
  • FIG. 14 shows a cross section of the container 40 in a use state
  • FIG. 17 shows a cross section of the container 40 in an unopened state.
  • the discharge member 30 is in a state where it is shallowly fitted to the container body 41.
  • the distal end 43 a of the inner plug 43 is in contact with the flange 39 provided on the inner surface of the discharge portion 31.
  • the flow path 34 of the discharge member 30 is divided by the flange 39 and the distal end 43 a of the inner plug 43, and the aseptic state of the liquid contained in the container body 21 is reduced. It can be maintained at a higher level and can prevent the deterioration of the content liquid (air oxidation, etc.).
  • a cap 46 is screwed on the screw portion 31 h of the discharge portion main body 31a, and further, on the inner surface of the cap 46, a discharge member is provided.
  • a sponge 47 is arranged at a position in contact with the discharge hole 32 of 31. The sponge 47 holds the residual liquid 3 5 ′ remaining in the discharge hole 32 after the end of the discharge operation.
  • Reference numeral 46 a is a cap 46 2 shows a threaded portion provided on the inner surface of a.
  • the opening end 46 b of the cap closes the ventilation hole 36 of the discharge member 30.
  • the second ejection member is not limited to the one described above, and may have a shape as shown in FIG. 18 for example.
  • the discharge member 30 ′ shown in FIG. 18 has a substantially cylindrical bottomed discharge part 31 having a discharge hole 32 at the bottom, and a discharge part 31. And a V-shaped valve element 3 3 ′, which is disposed inside of the valve element 3, when the discharge port 3 2 is mounted on the downstream end side of the discharge port 3 1 when the discharge port 3 2 is set to the downstream side D. And a vent hole 36 communicating with the flow path 35 via a ventilation filter 37, and further upstream from the valve seat portion 34. There is provided a liquid passage filter 38 arranged in the U and covering the flow path 35.
  • the discharge member 30 has a shape different from the shape of the valve body 31 and a shape in the vicinity of the discharge hole 32 of the discharge part 31 for accommodating the valve body 31, and includes a liquid passage filter 38 in the flow path 35. Except for this, it is the same as the discharge member 10 shown in FIG. 9 and the like.
  • the third discharge member 50 has, as shown in FIG. 19 (cross-sectional view) and FIG. 20 (exploded cross-sectional view), a bottomed substantially cylindrical discharge member having a discharge hole 52 at the bottom.
  • the discharge port 51 is disposed in the discharge section 51 and the discharge section 51 (the flow path 55 connected to the discharge port 52), and closes the discharge port 52 without receiving the hydraulic pressure from the upstream side U and closes the upstream side.
  • the elastic valve element 53 that expands and deforms when receiving the hydraulic pressure from U to open the discharge hole 52, and is connected to the flow path 55 upstream of the valve element 53 via the ventilation filter 57 via the ventilation filter 57. Vent holes 5 and 6 are provided.
  • the discharge section 51 needs to be provided with a ventilation filter 57 in the ventilation hole 56
  • the discharge section main body 51a having the discharge hole 52 and the upstream section U are provided at the mouth of a chemical solution container or the like. It is composed of two members, a connecting portion 5 1 b to be connected.
  • the discharge part body 51a and the connecting part 51b are ventilated to the flange 51f (connection part 51c). With the filter 57 sandwiched therebetween, they are integrated by joining means such as ultrasonic bonding.
  • FIG. 21 is a plan view (viewed from the upstream side U) of the discharge unit main body 5la.
  • a convex portion (valve seat) 52 b for connecting with a projection of the valve body 53 a is provided at the bottom of the substantially cylindrical discharge portion body 51 a.
  • ventilation holes 56 are provided at predetermined intervals in the flange 51 f (connection portion 51 c) for attaching the connecting portion 51 b that is paired with the discharge portion main body 51 a.
  • the ventilation hole 56 is provided with a ventilation filter 57 for realizing aseptic air inflow.
  • FIG. 22 shows a combined body of the valve body 53 and the valve body supporting member 54 for connecting the valve body 53
  • FIG. 22A is a plan view thereof (a view from the upstream side U).
  • Figure (b) is a bottom view (view from downstream D).
  • a valve element supporting member 54 for disposing the valve element 53 in the discharge part main body 51a is formed by a cylinder 54a and a valve element 53 at the bottom thereof. It has a locking portion 54b for realizing the connection, and a flange portion 54c at the opening end on the opposite side to fit with the discharge portion main body 51a.
  • valve body 53 is fitted to the inner surface 51 e of the discharge portion main body 51 a after being fixed to the valve body support member 54.
  • valve body 53 and the valve body support member 54 may be formed by insert molding or multiple molding. It can be integrally molded by color molding. Thereby, both members can be easily manufactured.
  • the molding material such as injection molding cannot be used because the elastic material forming the valve body 53 does not have thermoplasticity, for example, the valve body supporting member 5 is attached to a casting mold. By inserting the valve body 53 into the mold after insert 4, the valve body and the valve body support member 54 can be integrally formed.
  • the valve element 53 includes a valve body 53 a as a valve shaft, a projection 53 b at the tip of the valve body 53 a that forms a valve head, and a valve body 53. And a flange 53c for connecting the portion 53a to the valve body support member.
  • the elastic member shown in FIGS. 19 and 20 is configured such that the valve body 53 is connected to the opening end (see reference numeral 51 d in FIG. 20) of the discharge portion main body 51 a.
  • the first discharge member 50 is used by being attached to the mouth of a container body 61 as shown in FIG. 24, for example.
  • an inner stopper 63 is provided at the neck 62 of the container body 61.
  • FIG. 25 (a) shows a state in which no pressure is applied to the container body 61. In this state, the space between the flow path 55 in the discharge hole 52 and the flow path 55 upstream of the valve 53 is closed by the valve 53, and the discharge hole 52 and the container body are closed. 6 Communication with 1 is blocked. Therefore, the content liquid 64 stored in the container body 61 is not discharged from the discharge part 51 and stays in the container body 61 and the discharge member 50.
  • FIG. 25 (b) shows a state in which pressure is applied to the container body 61.
  • FIG. 26 (a) is a continuation of the state shown in FIG. 25 (b), and shows a state in which pressurization of the container body 61 is stopped.
  • FIG. 26 (b) is a continuation of the state shown in FIG. 26 (a), and shows a state in which the container body 61 is trying to restore the shape before pressurization.
  • the valve member 53 of the discharge member closes the flow path 55 at the convex portion 52 b of the discharge portion, and thus moves to the container body 61.
  • FIGS. 24 and 27 the inner plug 63 is inserted into the neck 62 of the container 60.
  • the function of the inner plug 63 is the same as that of the container 40 including the second discharge member 30 described above.
  • FIG. 24 shows a cross section of the container 60 in the used state
  • FIG. 27 shows a cross-sectional view of the container 60 in an unopened state.
  • reference numeral 63 a indicates a distal end portion of the inner plug 63
  • reference numeral 59 indicates a flange provided on the inner surface of the discharge portion 51.
  • a cap 66 is further screwed on the screw portion 51 h of the discharge portion main body 51a, and further, on the inner surface of the cap 66, A sponge 67 is disposed at a position in contact with the discharge hole 52 of the discharge member 51.
  • the open end 66 b of the cap closes the ventilation hole 56.
  • the functions of the sponge 67 and the opening end 66 b of the cap are the same as those in the case of the container 40 including the second discharge member 30.
  • reference numeral 66 a denotes a screw portion provided on the inner surface of the cap 66.
  • the fourth discharge member 70 includes a bottomed substantially cylindrical discharge portion 71 having a discharge hole 72 at the bottom, and an outer surface side of the discharge portion 71. From the valve seat 74, closes the discharge hole 72 when not receiving the hydraulic pressure from the upstream side U, and expands and deforms when receiving the hydraulic pressure from the upstream side U to open the discharge hole 72.
  • An elastic valve element 73 and a ventilation hole 76 connected to a flow path upstream of the valve element 73 via a ventilation filter 77 are provided.
  • the discharge section main body 71 a having the discharge hole 72 and the upstream thereof is composed of two members, a connecting portion 71b which is arranged on the side U and connected to the mouth of the drug solution container or the like.
  • the discharge unit main body 71a and the connecting part 71b are integrated by a bonding means such as ultrasonic bonding with the ventilation filter 77 sandwiched between the flange 71f (connection part 71c). Be transformed into
  • FIG. 29 (a) is a bottom view of the discharge unit main body 7la (a view as viewed from the downstream side D), and FIG. 29 (b) is a sectional view taken along line AA of FIG.
  • the discharge section body 7 la has this
  • connection part 71 c for attaching the connecting part 71 b that is to be paired with the same, close the multiple ventilation holes 76 and these ventilation holes as shown in Fig. 21
  • a ventilation filter 77 is provided.
  • the functions of the vent hole 76 and the vent filter 77 are the same as in the case of the container 60 including the third discharge member 50 described above.
  • the valve element 73 is provided on the outer surface of the bottom of the discharge unit body 71a, which is a substantially cylindrical member with a bottom, and on the bottom of the discharge unit body 71a.
  • the flow path 75 is partitioned so as to be in contact with both the bottom surface (outer surface) of the valve seat 74 for closing the discharge portion.
  • the valve body 73 is preferably formed integrally with the discharge section body 71a on the outer surface side of the resin discharge section body 71a using, for example, an elastic material having thermoplasticity. By integral molding, the production of the discharge member 70 can be simplified.
  • the fourth discharge member 70 is used by being attached to the mouth of the container body 81, for example, as shown in FIG.
  • an inner stopper 83 is provided on a neck portion 82 of the container body 81.
  • the function of the inner plug 83 is the same as that of the container 40 having the second discharge member 30 and the container 60 having the third discharge member 50.
  • FIG. 30 and FIG. 31 show a series of steps of a discharging operation using the discharging member of the present invention and a container provided with the discharging member.
  • FIG. 30 (a) shows a state in which no pressure is applied to the container body 81. In this state, the flow path 75 in the discharge hole 72 is closed by the valve body 73, and the communication between the outside of the discharge hole 72 and the container body 81 is blocked. Therefore, the content liquid 84 stored in the container body 81 remains in the container body 81 and the discharge member 70 without being discharged from the discharge part 71.
  • FIG. 30 (b) shows a state where pressure is applied to the container body 81.
  • valve body 73 receives the hydraulic pressure from the upstream side U through the flow path 75, and the hydraulic pressure causes the expansion deformation toward the discharge hole 72 side. Therefore, a flow path is formed between the valve body 73 and the valve seat portion 74, and the content liquid 84 accommodated in the container body 81 becomes a droplet 85 as the discharge portion 71. Is discharged from.
  • FIG. 31 (a) is a continuation of the state shown in FIG. This shows a state in which the pressurization is stopped. In this state, since the liquid pressure due to the content liquid 84 is not applied to the valve element 73 of the discharge member, the shape is restored to the state before pressurization, and the valve element 73 and the valve seat 74 are returned again. Is closed.
  • FIG. 31 (b) is a continuation of the state shown in FIG. 31 (a), and shows a state where the container body 81 is trying to restore the shape before pressurization. In this state, since the valve body 73 of the discharge member closes the flow path 75 between the valve seat 74 of the discharge portion 71a and the outside air flowing into the container body 81, the valve body 73 has a rounded shape. This is realized through the ventilation holes 76.
  • a discharge member 70 ′ shown in FIG. 32 is another embodiment of the fourth discharge member.
  • the valve body 73 and the discharge portion main body 71a are integrally formed as shown in a discharge member 70 shown in FIG. Can be.
  • the valve body 73 is made of an elastic body other than the thermoplastic elastomer, that is, a rubber having no thermoplasticity, as long as it is sufficiently flexible and easily bends and deforms by hydraulic pressure. You may.
  • the elastic material forming the valve body cannot be molded by injection molding or the like because it does not have thermoplasticity, for example, as shown in the embodiment shown in FIG. May be disposed in the discharge portion 71 by being sandwiched between the discharge portion main body 7 la 'and the valve seat 74 (and the cylindrical body 74 a).
  • the discharge member 70 shown in FIG. 32 is the same as the discharge member 70 shown in FIG. 28 except that the discharge part main body 71 a and the valve element 73 ′ are different.
  • the fifth discharge member 90 includes, as shown in FIG. 33, for example, a substantially cylindrical bottomed discharge portion 91 having a hole 91 d at the bottom, and a substantially annular valve body portion 93. b and a substantially annular thin portion 93a connected thereto, and discharges the valve body 93b with the thin portion 93a exposed through the hole 91d to the outside of the discharge portion 91.
  • the discharge hole 92 is normally closed by a thin portion 93a of the valve body 93. 9572
  • the valve body 93 has a thin portion 93 a exposed to a hole 91 d of the discharge portion 91 (discharge portion main body 9 la), and the discharge portion main body 91 It is fixed to the inner surface of a.
  • reference numeral 94 c denotes a valve body supporting member 94 that holds the valve body supporting portion 94 a and the flange portion 94 b and moves the valve body supporting member 94 into the discharging portion 91 (the discharging portion body 9 la).
  • 3 shows a tubular portion to be fixed. It is sufficient that the valve body 93 b has a sufficient thickness to be integrated with the inner surface of the discharge body 91 a.
  • the discharge section main body 91a having the discharge hole 92 and the upstream section U and the opening of the chemical solution container are provided. It is composed of two members, a connecting part 9 1b to be connected.
  • the discharge unit main body 91a and the connecting part 91b are integrated by a joining means such as ultrasonic bonding with the ventilation filter 97 sandwiched between the connecting parts 91c.
  • the fifth discharge member 90 is used by being attached to the mouth of the container body 101, for example, as shown in FIG.
  • FIGS. 36 and 37 show a series of steps of a discharging operation using the fifth discharging member 90 and the container 100 including the same according to the present invention.
  • FIG. 36 (a) shows a state in which no pressure is applied to the container body 101, and in this state, the valve member 93 of the discharge member closes the discharge hole 92. Therefore, the liquid solution 104 accommodated in the container body 101 is not discharged from the discharge part 91 and stays in the container body 101 and the discharge member.
  • FIG. 36 (b) shows a state in which pressure is applied to the container body 101. In this state, a fluid pressure due to the content liquid 104 is applied to the valve element 93 of the discharge member from the upstream side U, and the valve element 95 expands and deforms.
  • FIG. 38 is an enlarged view of the state of the discharge section 91 shown in FIG. 36 (b).
  • FIG. 37 (a) is a continuation of the state shown in FIG. 36 (b). This shows a state in which pressurization of the container body 101 is stopped. In this state, the valve of the discharge member 9 3 Since the liquid pressure by the content liquid 104 is not applied to the valve, the valve body 93 is restored to the shape before pressurization, and the discharge hole 92 is closed again.
  • FIG. 37 (b) is a continuation of the state shown in FIG. 37 (a). By stopping the pressurization of the container main body 101, the container main body 101 becomes the shape before pressurization. Shows the state that is about to be restored. In this state, since the valve member 93 of the discharge member closes the discharge hole 92, the inflow of the outside air into the container body 101 is realized exclusively through the vent hole 96.
  • FIG. 34 shows a cross section of the container 100 in a use state.
  • Figure 3 and Figure 17 show the state in which the tip 103a of the inner plug 103 is engaged with the flange 99 (that is, the unplugged state) and the effect of the engagement of both. This is the same as in the other embodiments shown in FIGS.
  • a cap 106 is screwed on the outer surface of the discharge portion main body 91a.
  • the cap 106 is provided with a recessed portion 108 at a position facing the discharge hole 92 in a state of being screwed with the discharge portion main body 9 la, and the cap 10 is formed in the recessed portion 108.
  • the inner surface of 6 and the discharge hole 92 are in contact with each other.
  • a sponge 107 is provided around the recess 108, and the residual liquid 105 ′ (see FIG. 37 (b)) remaining in the discharge hole 92 is formed in the recess 108. Is displaced by the cap inner surface and absorbed by the sponge 107.
  • the open end 106a of the cap closes the ventilation hole 96 of the discharge member 90.
  • the solvent (water) of the chemical solution contained in the container body 101 evaporates gradually from the ventilation filter 97 and the pH of the contained solution fluctuates.
  • Valve body 9 3 b ′ Force The flow path 95 is also closed by contact with the flange portion 94 b of the valve body support member 94.
  • FIG. 40 shows an enlarged view of the state of the discharge section 91 of the discharge member 90 ′ shown in FIG. 38.
  • the open / close position of the flow passage 95 (the contact position between the thin film portion 93 a and the valve body support portion 94 a, the valve body portion 9 3 b ′)
  • a liquid passage filter (not shown) may be provided upstream of the flange portion 94b (contact position with the flange portion 94b). The effect of providing the liquid passage filter is the same as in the other embodiments shown in FIGS. 6, 18 and the like.
  • the outer diameter of the valve body support portion 94a is set in the range of 0.6 to 2.0 mm, preferably 1.0 to 1.2 mm.
  • the thickness of the valve body 93 at the thin film portion 93a is set in the range of 0.8 to 2.5 mm, preferably 0.8 to 1.5 mm.
  • the thin film portion 93a of the valve body is slightly expanded by the valve body support portion 94a. Therefore, it is preferable to set the inner diameter of the thin film portion 93a in a state where the valve body support portion 94a is not passed through so as to be smaller than the outer diameter of the valve body support portion 94a. .
  • the inner diameter of the thin film portion 93a is 50 to 99%, preferably 50 to 90%, more preferably 60 to 90% with respect to the outer diameter of the valve body support portion 94a. It should be set so as to be 80%. As shown in FIG.
  • valve element of the discharge member according to the present invention is easily compressed or expanded by the liquid pressure from the container body side and by the liquid pressure lower than the liquid pressure of the gas filter, and furthermore, the gas pressure from the outside of the gas filter is low. It must be one that does not cause compression or extension deformation.
  • materials usable for the valve body include low-hardness thermoplastic elastomers; gel-like substances; and rubbers such as natural rubber, silicone rubber, isoprene rubber, butyl rubber, butadiene rubber, and fluorine rubber. .
  • the hardness of the force valve body is determined by the JISA hardness (JIS 6301-5. 2
  • the spring hardness Hs (A type) measured by the method described in “Spring hardness test” is required to be in the range of 0 to 40.
  • the hardness (JISA) of the valve body is particularly preferably 30 or less, more preferably 20 or less, and still more preferably 10 or less in the above range.
  • the lower limit of the hardness of the valve body (JISA) is not further limited than the above range, but from the viewpoint of material availability, strength of the valve body, etc., it may be 2 or more according to JISA. .
  • thermoplastic elastomers include styrene-ethylene / butylene-styrene block copolymer (SEB S), styrene-butadiene-styrene block copolymer (SB S), and styrene-isoprene-styrene block copolymer (SIS) , Maleic acid modified SEBS, styrene-ethylene / propylene-styrene block copolymer (SEPS), styrene-ethylene / butylene block copolymer (SEB), styrene-ethylene / propylene block copolymer (SEB) Styrene-based elastomers such as SEP); olefin-based elastomers such as ethylene-propylene block copolymer; polyurethane-based elastomers; and mixtures thereof.
  • SEB S styrene-ethylene / butylene-styren
  • the gel-like substance examples include a gel composed of a linear hydrocarbon polymer (olefin elastomer) [such as “Cosmogel” manufactured by Cosmo Keiki Co., Ltd.); Name "Chemitec Gel”.
  • a gel composed of a linear hydrocarbon polymer (olefin elastomer) such as “Cosmogel” manufactured by Cosmo Keiki Co., Ltd.); Name "Chemitec Gel”.
  • the elastic body forming the valve body may be a foamed body (provided that the pores are discontinuous and do not allow liquid to pass through), and even if the hardness is set to the above range by an additive.
  • Indices indicating the degree of deformation of the valve element due to hydraulic pressure include, for example, tensile stress and compression elastic modulus of the elastic body in addition to the above hardness.
  • the elastic body used for the valve body has its compression set CS (JISK 7301, measurement condition: 70 ° C x 22 hours) so that it will not be damaged by repeated application and removal of hydraulic pressure. Is preferably 50 or less.
  • the discharge member is the discharge part of the eye drop container, considering that the dropping speed of the eye drop in a general eye drop operation is about 0.05 mL Z seconds, the valve body is compressed or expanded and deformed.
  • the pressure required for this is preferably about 0.01 to 0.2 MPa.
  • valve bodies 33, 33 ' are fixed to the inner surface (31e) of the discharge portion 31 as in the discharge members 30, 30' shown in FIGS.
  • a material having thermoplasticity may be selected, and the valve bodies 33, 33 'and the discharge portion main body 31a may be integrally formed.
  • a material having thermoplasticity is selected from the above-described elastic materials, and a valve body 73, What is necessary is just to integrally mold the discharge part main body 71a.
  • the discharge portion 70 is sandwiched between a discharge portion main body 71 a ′ and a cylindrical body 74 a connected to the valve seat 74, so that the discharge portion 70
  • the elastic material for forming the valve body is not limited to a material having thermoplasticity.
  • the ventilation filter used in the present invention has a liquid passing pressure exceeding a pressure that causes two forms of compression and expansion in the deformation of the valve body of the discharge member, and a flow from the outside. It is required that the pressure be lower than the pressure at which the discharge port is opened.
  • the drop rate of the eye drop in a general eye drop operation is about 0.05 mLZ second, and in that case, the shape of the valve body deformation
  • the liquid pressure of the ventilation filter is at least 0.0 IMPa, and is preferable. If the pressure exceeds 0.2 MPa, it is possible to prevent the ophthalmic solution from leaking from the vent during the eye dropping operation.
  • the rate at which air flows into the eyedropper (inhalation speed) after dropping eyedrops in a general eyedropping operation is about 1 to 1 OmL / sec.
  • the ventilation pressure of the ventilation filter is at least lower than 0.005 MPa, preferably lower than 0.005 IMPa, smooth introduction of outside air from the ventilation hole can be achieved.
  • the pore size of the ventilation filter is set so that the liquid (content liquid such as a chemical solution contained in the container of the present invention) discharged by the discharge member of the present invention, microorganisms such as bacteria, dust in the air, dust and the like do not pass. It is set to a range that allows only air to pass through, and is usually set to about 0.1 to 0.45 ⁇ , preferably to about 0.1 ⁇ .
  • aeration filter examples include, but are not limited to, hydrophobic polytetrafluoroethylene (PTFE) membrane of Japan Gore-Tex Co., Ltd., and Sure Vent of Japan Millipore Co., Ltd.
  • Dyurapore (R) Made of polyvinylidene fluoride (PVDF)].
  • the liquid passing filter used in the present invention is a filter that allows liquid permeation by applying a certain or more liquid pressure.
  • a liquid passage filter is provided on the upstream side of the discharge hole, as described above, even in the event that the residual liquid in the discharge hole flows backward, the residual liquid is applied to the discharge member.
  • the filter can prevent entry into the connected container body.
  • liquid passage filter usable in the present invention examples include, but are not limited to, hydrophilic PTFE membrane of Japan Gore-Tex Co., Ltd., hydrophilic Durapore (R) (manufactured by Nippon Millipore) (PVDF), The company's hydrophilic polyethersulfone (PES) membrane is an example.
  • the antibacterial treatment may be performed on the cap placed on the outer surface of the discharge part together with or instead of the antibacterial treatment on the discharge holes.
  • the part of the cap to be subjected to the antibacterial treatment is not limited to this, but may be a part of the inner surface that is in contact with the discharge hole, a sponge disposed inside the cap, or the like.
  • the discharge member of the present invention does not cause a backflow from the discharge hole side to the upstream side, the residual liquid after the discharge operation does not flow into the discharge part but remains around the discharge hole. Will do. Therefore, for example, using a cap with an absorbing material inside, the content liquid (residual liquid) that stays in the vicinity of the discharge hole after the discharging operation is sucked up by the absorbing material, so that when the dropping operation is performed again, The residual liquid can be prevented from being discharged (see Figs. 17 and 27).
  • the sponge is designed so that the sponge does not come into direct contact with the spout, and the residual liquid in the spout, which has been pushed away on the inner surface of the cap, is absorbed by the absorbent material provided around the inner surface of the cap. (See Figure 35).
  • the absorbent include, for example, urethane and foamed polyethylene. Sponge; cloth made of non-woven fabric, absorbent cotton, gauze; etc .; paper, hydrogel and the like.
  • Various known materials such as urethane and foamed polyethylene may be used for forming the sponge.
  • the agent is attached to the surface of the sponge by means such as coating, or a drug such as an antibacterial agent is mixed in urethane or polyethylene in advance. Is preferred.
  • a material having antibacterial properties may be used in advance as the material of the absorbent.
  • Examples of the antibacterial treatment on the cloth, paper, hydrogel, and the like include a method of subjecting them to treatment such as silane coupling and selenium coating.
  • Specific examples of the hydrogel include, for example, those obtained by combining a high molecule such as (meth) acrylamide and a water-swellable clay mineral (Japanese Patent Application Laid-Open No. 2002-53036, Japanese Patent Application Laid-Open No. 200-200). 2-5 3 7 6 2).
  • Examples of the resin forming the ejection member, the cap, and the container body include polyethylene (PE) and polypropylene (PP).
  • PE and PP are pharmaceutically safe materials, they are particularly suitable when the container of the present invention contains a drug solution such as an ophthalmic container.
  • the resin that forms the discharge member, cap and container body prevents liquid remaining in the vicinity of the discharge hole after the discharge operation and decay of the content liquid contained in the container body.
  • a preservative or the like may be previously kneaded.
  • Specific examples of preservatives include quaternary ammonium salts [for example, “Dimmer 38 (R)” manufactured by Iny Corporation, and “Dimmer 13 36 (R)” manufactured by the company).
  • quaternary ammonium salts for example, “Dimmer 38 (R)” manufactured by Iny Corporation, and “Dimmer 13 36 (R)” manufactured by the company).
  • a preservative is applied to the inner surface and the like by applying a means such as coating, or a surface treatment such as silane coupling is performed when forming the discharge member, cap and container body. You may put it.
  • a material having antibacterial activity may be used as a resin material itself for forming the ejection portion and the like.
  • FIG. 1 is a cross-sectional view showing one embodiment of the first ejection member.
  • FIG. 2 is a cross-sectional view illustrating an embodiment of the container including the first discharge member.
  • FIG. 3 is a cross-sectional view showing an unopened state of the container shown in FIG.
  • FIG. 4 is a cross-sectional view showing a use state of the container shown in FIG.
  • FIG. 5 is a sectional view showing a continuation of FIG.
  • FIG. 6 is a cross-sectional view illustrating another embodiment of the container including the first discharge member.
  • FIG. 7 is a cross-sectional view illustrating another embodiment of the first discharge member.
  • FIG. 8 is a sectional view showing still another embodiment of the first discharge member.
  • FIG. 9 is a sectional view showing an embodiment of the second ejection member.
  • FIG. 10 is a cross-sectional view showing a state where the ejection member 30 shown in FIG. 9 is disassembled.
  • FIG. 11 (a) is a plan view showing an example of an integrally formed product of the discharge portion main body 31a and the valve body 33, and
  • FIG. 11 (b) is a bottom view thereof.
  • FIG. 12 (a) is a plan view of the valve seat portion 34, and FIG. 12 (b) is a bottom view thereof.
  • Fig. 13 (a) is a plan view showing another example of an integrally molded product of the discharge part main body and the valve body,
  • valve seat 13 (b) is a plan view showing another example of the valve seat.
  • FIG. 14 is a cross-sectional view showing an embodiment of the container provided with the second discharge member.
  • FIG. 15 is a cross-sectional view showing a use state of the container shown in FIG.
  • FIG. 16 is a cross-sectional view showing a continuation of FIG.
  • FIG. 17 is a cross-sectional view showing an unopened state of the container 40 shown in FIG.
  • FIG. 18 is a cross-sectional view showing another embodiment of the second ejection member.
  • FIG. 19 is a sectional view showing an embodiment of the third ejection member.
  • FIG. 20 is an exploded sectional view of the discharge member 50 shown in FIG.
  • FIG. 21 is a plan view of the discharge unit main body 51 a shown in FIG.
  • FIG. 22 (a) is a plan view of the valve element supporting member 54 shown in FIG. 20, and FIG. 22 (b) is a bottom view thereof.
  • FIG. 23 is an explanatory view showing a method of assembling the discharge member 50 shown in FIG.
  • FIG. 24 is a cross-sectional view illustrating an example of a container including the discharge member 50 of FIG. 19.
  • FIG. 25 is a cross-sectional view illustrating a use state of the container 60 illustrated in FIG.
  • FIG. 26 is a cross-sectional view showing a continuation of FIG.
  • FIG. 27 is a cross-sectional view showing the container 60 shown in FIG. 24 in an unopened state.
  • FIG. 28 is a cross-sectional view illustrating an embodiment of the fourth ejection member.
  • FIG. 29 (a) is a bottom view of the discharge member 70 shown in FIG. 28, and FIG. 29 (b) is a sectional view taken along the line AA.
  • FIG. 30 (a) is a cross-sectional view showing an example of a container provided with a fourth discharge member 70
  • FIG. 30 (b) is a cross-sectional view showing the state of use.
  • FIG. 31 is a cross-sectional view showing a continuation of FIG. 30 (b).
  • FIG. 32 is a sectional view showing another embodiment of the fourth ejection member according to the present invention.
  • FIG. 33 is a cross-sectional view illustrating an embodiment of the fifth ejection member.
  • FIG. 34 is a cross-sectional view showing an embodiment of a container provided with a fifth discharge member.
  • FIG. 35 (a) is a cross-sectional view showing a state where a cap is attached to the container 100 shown in FIG.
  • FIG. 35 (b) is a sectional view showing the cap.
  • FIG. 36 is a cross-sectional view showing a use state of the container shown in FIG.
  • FIG. 37 is a cross-sectional view showing a continuation of FIG.
  • FIG. 38 is an enlarged cross-sectional view showing the discharge section of the container 100 shown in FIG. 36 (b).
  • FIG. 39 is a cross-sectional view showing another embodiment of the fifth discharge member.
  • FIG. 40 is an enlarged cross-sectional view of the discharge section in the use state of the container 100 ′ shown in FIG.
  • FIG. 41 (a) is a front view showing an example of a conventional eye drop container
  • FIG. 41 (b) is an enlarged sectional view of the discharge member.
  • FIG. 42 is an explanatory view showing a problem in a conventional eye drop container. Explanation of reference numerals
  • the deformation of the valve body is achieved by a liquid pressure lower than the liquid pressure of the ventilation filter, no liquid leakage occurs in the ventilation hole during the discharge operation, Discharge from the discharge hole can be reliably realized.
  • the opening of the discharge port and / or the flow path leading to the discharge port cannot be achieved by the external ventilation pressure to the ventilation filter, when outside air flows in through the discharge port instead of the ventilation port when the container body is restored. This does not cause the problem that the liquid content leaks from the discharge hole.
  • the container after the ejection process and the ejection operation can be highly prevented while the backflow of the liquid ejected from the ejection hole and the accompanying invasion of microorganisms and dust to the upstream side are highly prevented. Restoration can be performed smoothly.
  • the discharge member of the present invention is described in JP-A-201-17990 (Japan) ⁇ JP-A 201-204654 (Japan) described above.
  • a porous filter is not provided at the discharge section, so there is a very low risk of clogging of the discharge holes even when the liquid content is a suspension, for example. Low.
  • clogging does not usually occur in the discharge port if the particle size of the suspended particles is up to about 50 m.
  • the container of the present invention is provided with the discharge member of the present invention at the mouth thereof, the liquid once discharged flows back into the container body, and accordingly, microorganisms such as bacteria, dust, dust, etc. Can be prevented from penetrating into the body of the container, and therefore, the use of chemicals (for example, preservatives) to prevent spoilage or deterioration of the content liquid is eliminated, or the use of such chemicals is not required. Can be reduced as much as possible . Further, the container of the present invention does not use a porous filter in the discharge portion, and therefore does not cause clogging in the discharge hole. However, even if the content liquid is a suspension, smooth discharge can be realized.
  • the container of the present invention further includes an inner plug slidably held in the flow path of the discharge member or in the container body, and the inner plug comes into contact with the inner wall of the flow path of the discharge member when the container is not used.
  • the flow path is closed.
  • the sterile condition of the content liquid can be guaranteed airtight until the container is started to be used, and the content liquid can be prevented from contacting the valve element and the ventilation filter when not in use. Quality can be stabilized over a long period of time.
  • the container of the present invention is suitable, for example, as an ophthalmic container for storing an ophthalmic solution.

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Abstract

A discharge member from which liquid filled in a flexible container is discharged by pressing the container and a container provided with the discharge member on a mouth portion of the container are disclosed. The discharge member comprises a discharge portion with a substantially cylinder-like or substantially bowl-like form provided with a discharge hole in the bottom; a valve body formed of an elastic body which valve body closes the discharge hole and/or a flow passage in the discharge portion connected to the discharge hole when the valve body is not subjected to liquid pressure and opens the discharge hole and/or the passage when the valve body is deformed by liquid pressure; and an air vent connected to the discharge hole and the flow passage through an air-vent filter. The valve body can be deformed by liquid pressure that is lower than liquid passing pressure of the air-vent filter, and the discharge hole and/or the flow passage cannot be opened by passing pressure of air from outside to the air vent filter.

Description

ø月 、 e言  ø month, e word
吐出部材ぉよびそれを備える容器 技術分野  Discharge member and container with it
本発明は、 可撓性を有する容器に充填された内容液を当該容器の押圧によ つて吐出させるための吐出部材と、 当該吐出部材を備える容器とに関する。 背景技術  The present invention relates to a discharge member for discharging a liquid content filled in a flexible container by pressing the container, and a container provided with the discharge member. Background art
点眼容器のように内容液を滴下させて使用する容器においては、 例えば図 4 1 (a), (b) に示すような吐出部材 1 5 0が用いられる。 この吐出部材 1 5 0は容器本体 1 5 2の口部 1 5 2 aに取り付けられるものであって、 吐出孔 1 5 1の内径は、 容器本体 1 5 2を押圧することによって内容液を吐出させ ることができ、 かつ容器本体 1 5 2を押圧しないときに内容液が吐出されな いような大きさに設定され、 吐出口 1 5 3の径は、 内容液を液滴 1 5 4の状 態で保持し得る大きさに設定される。  In a container such as an eye drop container that is used by dripping the content liquid, for example, a discharge member 150 shown in FIGS. 41A and 41B is used. This discharge member 150 is attached to the mouth part 152 a of the container body 152, and the inner diameter of the discharge hole 151 is formed by discharging the content liquid by pressing the container body 152. It is set so that the content liquid is not discharged when the container body 15 2 is not pressed, and the diameter of the discharge port 15 3 It is set to a size that can be held in the state.
図 4 1に示すような容器においては、 吐出口 1 5 3に細菌等の微生物や埃 、 塵等が付着するおそれが高く、 とりわけ点眼容器の場合には、 角膜や瞼と の接触によって吐出口 1 5 3に微生物が付着するおそれが極めて高い。 また 、 容器から内容液を吐出させた後には、 押圧により変形した容器本体 1 5 2 を復元するために吐出口 1 5 3から外気を取り入れることから、 例えば図 4 2 (a) , (b) に示すように、 吐出口 1 5 3に付着した微生物、 埃等が吐出口 1 5 3に残留した内容液 (点眼液) 1 5 5とともに、 容器本体 1 5 2内に逆流 するおそれがある。 なお、 図 4 2 (b) 中、 符号 1 5 6は内容液 (点眼液) 1 5 5中の気泡を示す。  In the container shown in Fig. 41, there is a high possibility that microorganisms such as bacteria, dust, and dust adhere to the discharge port 153. Particularly in the case of eye drops, the discharge port is formed by contact with the cornea and eyelids. Microorganisms are extremely likely to adhere to 153. In addition, after the content liquid is discharged from the container, outside air is taken in from the discharge port 153 in order to restore the container main body 152 deformed by pressing, so that, for example, FIGS. 42 (a) and (b) As shown in, there is a risk that microorganisms, dust, etc. attached to the discharge port 1553 may flow back into the container body 152 together with the content liquid (ophthalmic solution) 1555 remaining at the discharge port 1553. In FIG. 42 (b), reference numeral 156 indicates a bubble in the content liquid (ophthalmic solution) 155.
容器本体の内部に微生物、 埃等が侵入すると、 内容液の腐敗、 劣化等を招 くことから、 例えば点眼容器に収容される点眼液には、 防腐剤としての塩化 ベンザルコニゥム、 パラベン類等が配合されている。 しかしながら、 点眼液 の種類によっては防腐剤を含む処方が困難であったり、 防腐剤を配合させる ことで点眼液の使用者にァレルギ一等の副作用が生じたりするおそれがある 。 それゆえ、 防腐剤を使用しないようにすること、 あるいはその使用量を極 カ少なくすることが検討されている。 If microorganisms, dust, etc. enter the inside of the container body, it may cause decay or deterioration of the liquid content.For example, benzalkonium chloride, parabens, etc., as preservatives, are incorporated in the ophthalmic solution contained in the ophthalmic container. Have been. However, depending on the type of the ophthalmic solution, it may be difficult to formulate a preservative containing the preservative, or the preservative may cause side effects such as allergic effects on the user of the ophthalmic solution. Therefore, avoid using preservatives, or limit their use. Reduction of power is being considered.
例えば近年、 防腐剤を使用せずに、 容器内に極めて少量の点眼液のみを密 封してなる、 いわゆる使い切りの点眼容器が提供されている。 この点眼容器 によれば防腐剤の不使用を実現できるものの、 コスト面の問題があること力、 ら、 特定の用途に限定されることとなり、 汎用されるものではない。  For example, in recent years, so-called single-use ophthalmic containers in which only a very small amount of ophthalmic solution is hermetically sealed without using a preservative have been provided. Although this ophthalmic container makes it possible to use no preservatives, it is limited to specific applications due to the cost problem and is not widely used.
特開 2 0 0 2— 8 0 0 5 5号公報 (日本) には、 外層と、 その内面に剥離 可能に設けられた内層とを備える、 いわゆるデラミネートボトルを採用した フィルタ付き吐出容器が記載されている。 この吐出容器によれば、 内容液の 吐出後においても吐出口から容器内部へと外気が流入するのを阻止されるこ とから、 内容液中への細菌類の混入を防止することができる。 しかしながら 、 内容液の吐出に伴う容器内圧の変化に対応させるベく、 上記内層により構 成される容易に変形可能な内容器を設ける必要があり、 容器の製造コストが 高くなるという問題がある。  Japanese Patent Application Laid-Open No. 2002-80055 (Japan) describes a discharge container with a filter that employs a so-called delaminated bottle that includes an outer layer and an inner layer that is provided on the inner surface so as to be peelable. Have been. According to this discharge container, even after the discharge of the content liquid, it is possible to prevent outside air from flowing into the container from the discharge port, so that it is possible to prevent bacteria from being mixed into the content liquid. However, in order to cope with a change in the internal pressure of the container due to the discharge of the content liquid, it is necessary to provide an easily deformable inner container composed of the above-mentioned inner layer, and there is a problem that the manufacturing cost of the container increases.
—方、 特開 2 0 0 1— 1 7 9 0 1 7号公報 (日本) ゃ特開 2 0 0 1— 2 0 6 4 5 4号公報 (日本) には、 流孔径の大きさを微生物や埃等が通過できな い程度とした多孔性フィルタを吐出口に配置してなる抗菌性容器が記載され ている。 しかしながら、 薬液等が染み込んだ状態で多孔性フィルタが乾燥し てしまうと、 薬液中の溶質によってフィルタに目詰まりを生じるおそれがあ る。 特に、 用途によっては点眼液が懸濁液である場合があり、 このような場 合には目詰まりの問題がより一層生じ易くなる。 さらに、 特開 2 0 0 1— 1 7 9 0 1 7号公報 (日本) および特開 2 0 0 1 - 2 0 6 4 5 4号公報 (日本 ) に記載の容器では、 多孔質フィルタとして金属焼結体や樹脂焼結体等を用 いているが、 この場合、 焼結体の微粒子が薬液中に混じって容器から吐出さ れるおそれもある。 発明の開示  —On the other hand, Japanese Patent Application Laid-Open No. 2000-017-1709 (Japan) ゃ Japanese Patent Application Laid-Open No. 201001-2064 It describes an antibacterial container in which a porous filter, which is not capable of passing dust and the like, is disposed at a discharge port. However, if the porous filter is dried in a state in which the chemical solution or the like is impregnated, the filter may be clogged by a solute in the chemical solution. In particular, the ophthalmic solution may be a suspension depending on the application, and in such a case, the problem of clogging is more likely to occur. Further, in the containers described in Japanese Patent Application Laid-Open No. 2001-179907 (Japan) and Japanese Patent Application Laid-Open No. 2001-204654 (Japan), a metal filter is used as a porous filter. A sintered body or a resin sintered body is used, but in this case, there is a possibility that the fine particles of the sintered body are mixed with the chemical solution and discharged from the container. Disclosure of the invention
そこで本発明の目的は、 容器の口部にあって内容液を液滴として吐出させ るための部材であって、 内溶液の逆流を防止し、 かつ吐出操作後の容器内へ の空気の流入を無菌的に実現させることのできる吐出部材を提供することで め 。 Therefore, an object of the present invention is to provide a member at the mouth of a container for discharging the liquid content as droplets, to prevent backflow of the internal solution, and to allow air to flow into the container after the discharging operation. By providing a discharge member that can aseptically realize M
また、 本発明の他の目的は、 内容液の腐敗または劣化を防止するための薬 剤の配合をなくしまたはその配合を抑制することができ、 しかも当該内容液 が懸濁液であっても吐出口での目詰まりを生じさせることなく、 スムーズな 吐出を実現することのできる容器を提供することである。  Another object of the present invention is to eliminate or suppress the compounding of a chemical for preventing decay or deterioration of the content liquid, and to discharge the liquid even if the content liquid is a suspension. An object of the present invention is to provide a container capable of realizing a smooth discharge without causing clogging at an outlet.
〔吐出部材〕  (Discharge member)
上記課題を解決するための本発明の吐出部材は、 底部に吐出孔を備える有 底略筒状または略椀状の吐出部と、 上記吐出孔側を下流側としたときに、 上 流側から液圧を受けていない状態で上記吐出孔ぉよび Zまたは当該吐出孔に つながる吐出部内の流路を閉鎖し、 かつ上流側から液圧を受けると変形して 当該吐出孔ぉよび/または流路を開放する、 弾性体からなる弁体と、 通気フ ィルタを介して上記弁体よりも上流側の流路につながる通気孔とを備え、 上 記弁体の変形が上記通気フィルタの通液圧よりも小さい液圧によって達成さ れかつ上記吐出孔および/または上記流路の開放が、 上記通気フィルタへの 外部からの通気圧では達成されないものであることを特徴とする。  A discharge member according to the present invention for solving the above-mentioned problems has a bottomed substantially cylindrical or bowl-shaped discharge portion having a discharge hole at a bottom portion, and the discharge hole side is defined as a downstream side. Closes the discharge hole and Z or the flow path in the discharge part connected to the discharge hole without receiving the hydraulic pressure, and deforms when receiving the hydraulic pressure from the upstream to deform the discharge hole and / or the flow path. A valve body made of an elastic body, and a ventilation hole connected to a flow path on the upstream side of the valve body via a ventilation filter. And the opening of the discharge hole and / or the flow path is not achieved by an external ventilation pressure to the ventilation filter.
本発明の吐出部材において、 吐出孔および流路の閉鎖と開放とを制御する 弁体は、 弾性体からなるものであって、 上流側から液圧を受けていない状態 で吐出孔および/または流路を閉鎖し、 上流側から液圧を受けると変形を生 じて吐出孔ぉよび /または流路を開放する。 吐出孔ぉよび Zまたは流路が開 放されると、 当該吐出孔と、 吐出部の上流側 (具体的には、 本発明の吐出部 材に連結される点眼容器等の容器本体) とが連通することとなって、 吐出孔 からの薬液等の吐出を実現することができる。  In the discharge member of the present invention, the valve body that controls the closing and opening of the discharge hole and the flow path is made of an elastic body, and is configured to receive the discharge hole and / or the flow while receiving no hydraulic pressure from the upstream side. The passage is closed, and when receiving hydraulic pressure from the upstream side, it deforms and opens the discharge hole and / or the flow passage. When the discharge holes and Z or the flow path are opened, the discharge hole and the upstream side of the discharge portion (specifically, a container body such as an eye drop container connected to the discharge member of the present invention) are formed. By communicating with each other, discharge of a chemical solution or the like from the discharge hole can be realized.
本発明の吐出部材において吐出孔からの薬液等の吐出を実現するには、 例 えば当該吐出部材に連結される点眼容器等の容器本体に圧を加えればよい。 かかる加圧に伴って、 吐出部材の弁体に上流側から内容液 (薬液等) の液圧 がかかることとなり、 これによつて弁体が変形して上記吐出孔および/また は流路が開放される。 一方、 上記の吐出操作を終えた後では、 変形を受けた 容器本体がその形状を復元させるために通気孔から外気を流入させようとす る。 ここで、 本発明の吐出部材によれば、 内容液の流路と連通する通気孔に 通気フィルタが備えられていることから、 吐出操作後における容器内への空 気の流入を無菌的に達成することができる。 In order to achieve the discharge of a drug solution or the like from the discharge hole in the discharge member of the present invention, for example, pressure may be applied to a container body such as an eye drop container connected to the discharge member. With this pressurization, the liquid pressure of the content liquid (chemical solution, etc.) is applied to the valve body of the discharge member from the upstream side, whereby the valve body is deformed and the discharge hole and / or the flow path is formed. Be released. On the other hand, after the above-described discharge operation is completed, the deformed container body tries to flow outside air from the ventilation holes in order to restore its shape. Here, according to the discharge member of the present invention, the vent hole communicating with the flow path of the content liquid is provided. Since the ventilation filter is provided, inflow of air into the container after the discharging operation can be aseptically achieved.
吐出操作を終えた後に、 吐出部材に連結された容器本体の内部で生じる、 外気を流入させようとする陰圧は、 変形を受けた弁体の復元動作を加速する 作用を示す。 それゆえ、 吐出操作を行うことによって弁体と吐出部との間に 形成された隙間 (流路) は、 容器本体への加圧を取り除くことによって直ち に塞がれることとなり、 本発明の吐出部材における弁体は逆止弁として作用 する。  After the discharge operation is completed, the negative pressure generated inside the container body connected to the discharge member for allowing the outside air to flow has an effect of accelerating the restoration operation of the deformed valve element. Therefore, the gap (flow path) formed between the valve element and the discharge part by performing the discharge operation is immediately closed by removing the pressurization to the container body, and the present invention The valve element in the discharge member acts as a check valve.
本発明に係る吐出部材の実施態様としては、 例えば以下に示す第 1〜第 5 の実施形態が挙げられる。  Embodiments of the ejection member according to the present invention include, for example, first to fifth embodiments described below.
(第 1の実施形態)  (First Embodiment)
本発明に係る第 1の吐出部材は、 底部に吐出孔を備える有底略筒状または 略椀状の吐出部と、 当該吐出部内に配置されて、 上記吐出孔側を下流側とし たときに上流側から液圧を受けていない状態で上記吐出孔を閉鎖し、 かつ上 流側から液圧を受けると圧縮変形して当該吐出孔を開放する、 弾性体からな る弁体と、 上記吐出部の内部に配置されて吐出部内表面との間に流路を区画 しかつ上流側において上記弁体を固定する繋止部と、 通気フィルタを介して 上記弁体よりも上流側の流路とつながる通気孔と、 を備え、 上記弁体の圧縮 変形が上記通気フィルタの通液圧よりも小さい液圧によって達成されかつ上 記吐出孔および/または上記流路の開放が、 上記通気フィルタへの外部から の通気圧では達成されないものであることを特徴とする。  The first discharge member according to the present invention includes a bottomed substantially cylindrical or bowl-shaped discharge portion having a discharge hole at a bottom portion, and a discharge portion disposed in the discharge portion, wherein the discharge hole side is a downstream side. A valve body made of an elastic body, which closes the discharge hole in a state where the discharge pressure is not received from the upstream side, and is compressed and deformed to open the discharge hole when receiving the hydraulic pressure from the upstream side; A locking section disposed inside the section and defining a flow path between the inner surface of the discharge section and fixing the valve element on the upstream side; and a flow path on the upstream side of the valve element via a ventilation filter. And a connecting vent, wherein the compression deformation of the valve body is achieved by a fluid pressure lower than the fluid pressure of the vent filter, and the opening of the discharge port and / or the flow path is provided to the vent filter. It cannot be achieved by external ventilation pressure. I do.
第 1の吐出部材において、 吐出部の内部に配置される弾性体からなる弁体 は、 吐出孔を弁座として流路の閉鎖と開放とを制御するものである。 この弁 体は、 上流側から液圧を受けていない状態で吐出孔を閉鎖し、 上流側から液 圧を受けると圧縮変形を生じて吐出孔を開放する。 吐出孔が開放される結果 、 当該吐出孔と、 吐出部の内表面と繋止部との間に区画される流路とが連通 することとなって、 吐出部からの薬液等の吐出を実現することができる。 第 1の吐出部材において、 吐出孔からの薬液等の吐出を実現するには、 前 述したのと同様に、 当該吐出部材に連結される容器本体に圧を加えればよい 。 吐出操作終了後の弁体の復元に際して、 通気フィルタから無菌的に空気を 流入させ得ることや、 外気を流入させようとする陰圧によって変形を受けた 弁体の復元動作が加速されること (それゆえ弁体を逆止弁として作用させ得 ること) については、 前述の場合と同様である。 In the first discharge member, the valve body made of an elastic body disposed inside the discharge section controls closing and opening of the flow path using the discharge hole as a valve seat. This valve element closes the discharge hole in a state where it is not receiving the hydraulic pressure from the upstream side, and when it receives the hydraulic pressure from the upstream side, it compressively deforms to open the discharge hole. As a result of the opening of the discharge hole, the discharge hole communicates with the flow path defined between the inner surface of the discharge portion and the locking portion, thereby realizing discharge of a chemical solution or the like from the discharge portion. can do. In the first discharge member, in order to realize the discharge of the chemical solution or the like from the discharge holes, pressure may be applied to the container body connected to the discharge member in the same manner as described above. . When the valve is restored after the discharge operation, the air can be aseptically introduced from the ventilation filter, and the restoration operation of the valve that has been deformed by the negative pressure that tries to allow the outside air to be accelerated ( Therefore, the fact that the valve body can act as a check valve) is the same as in the case described above.
第 1の吐出部材において、 弁体の圧縮変形は通気フィルタの通液圧よりも 低い液圧によつて達成されることから、 吐出操作の際に通気孔において液漏 れを生じることがない。 しかも、 吐出孔および/または当該吐出孔につなが る吐出部内の流路の開放は、 通気フィルタへの外部からの通気圧では達成さ れないことから、 容器本体の復元時に通気孔ではなく吐出孔から外気が流入 したり、 これに伴って吐出孔から内容液が漏れ出したりすることがない。 従って、 本発明に係る第 1の吐出部材によれば、 吐出孔から吐出された液 体の逆流およびそれに伴う微生物や埃等の上流側への侵入を高度に防止しつ つ、 吐出処理と吐出操作後における容器の復元とをスムーズに行うことがで さる。  In the first discharge member, since the compression deformation of the valve body is achieved by a liquid pressure lower than the liquid pressure of the ventilation filter, liquid leakage does not occur in the ventilation hole during the discharge operation. In addition, since the opening of the discharge hole and / or the flow path in the discharge portion connected to the discharge hole cannot be achieved by the external ventilation pressure to the ventilation filter, the discharge hole is used instead of the ventilation hole when the container body is restored. There is no possibility that outside air flows in from the outlet or the contents liquid leaks out of the discharge holes. Therefore, according to the first discharge member of the present invention, the discharge process and the discharge process can be performed while preventing the liquid discharged from the discharge hole from flowing backward and the microorganisms and dust accompanying the discharge from entering the upstream side to a high degree. Restoration of the container after operation can be performed smoothly.
第 1の吐出部材において、 弁体と繋止部とは一体成形してなるものである のが好ましい。 弁体と繋止部とを一体成形することによって、 吐出部材の生 産工程を効率化することができる。 弁体と繋止部とを一体成形する方法とし ては、 例えば多色成形ゃィンサート成形が挙げられる。  In the first discharge member, it is preferable that the valve body and the locking portion are integrally formed. By integrally molding the valve body and the locking portion, the production process of the discharge member can be made more efficient. As a method of integrally molding the valve body and the locking portion, for example, multicolor molding insert molding is used.
(第 2の実施形態)  (Second embodiment)
本発明に係る第 2の吐出部材は、 底部に吐出孔を備える有底略筒状または 略椀状の吐出部と、 当該吐出部内に固定されてなる弁座と、 上記吐出部の内 表面に固定されて、 上記吐出孔を下流側としたときに上流側から液圧を受け ていない状態で上記弁座に下流側から当接して当該吐出孔につながる流路を 閉鎖し、 力、つ上流側から液圧を受けると圧縮変形して当該弁座との間に流路 を開放する、 弾性体からなる略筒状の弁体と、 通気フィルタを介して上記弁 体よりも上流側の流路とつながる通気孔と、 を備え、 上記弁体の圧縮変形が 上記通気フィルタの通液圧よりも小さい液圧によって達成されかつ上記吐出 孔および/または上記流路の開放が、 上記通気フィルタへの外部からの通気 圧では達成されないものであることを特徴とする。 第 2の吐出部材において、 吐出部の内部に配置される弾性体からなる弁体 は、 同じく吐出部の内部に配置される弁座部と対になって、 流路の閉鎖と開 放とを制御する。 この弁体は、 上流側から液圧を受けていない状態で弁座に 当接して、 吐出孔と吐出部の上流側とをつなぐ流路を閉鎖する。 一方、 上流 側から液圧を受けると圧縮変形を生じて、 弁座との間に空隙を形成する (弁 座との間隙を開放する) 。 弁座との間に空隙が形成される結果、 弁体の上流 側と吐出孔との流路が連通することとなって、 吐出孔からの薬液等の吐出を 実現することができる。 The second discharge member according to the present invention includes a bottomed substantially cylindrical or bowl-shaped discharge portion having a discharge hole at a bottom portion, a valve seat fixed in the discharge portion, and an inner surface of the discharge portion. When the discharge port is fixed to the downstream side, the flow path connected to the discharge port by contacting the valve seat from the downstream side in a state where the fluid pressure is not received from the upstream side is closed. When receiving fluid pressure from the side, it compresses and deforms to open a flow path between the valve and the valve seat. A substantially cylindrical valve body made of an elastic body, and a flow upstream from the valve body via a ventilation filter And a vent hole connected to a passage, wherein the compression deformation of the valve body is achieved by a fluid pressure smaller than the fluid pressure of the vent filter, and the opening of the discharge hole and / or the flow path is transmitted to the vent filter. Not achieved by external ventilation pressure . In the second discharge member, a valve body made of an elastic body disposed inside the discharge part is paired with a valve seat part also disposed inside the discharge part to close and open the flow passage. Control. The valve body abuts on the valve seat without receiving the hydraulic pressure from the upstream side, and closes a flow path connecting the discharge hole and the upstream side of the discharge portion. On the other hand, when it receives hydraulic pressure from the upstream side, it undergoes compressive deformation and forms a gap with the valve seat (opens the gap with the valve seat). As a result of the formation of the gap between the valve seat and the valve seat, the flow path between the upstream side of the valve body and the discharge hole communicates with each other, so that the discharge of a chemical solution or the like from the discharge hole can be realized.
第 2の吐出部材において、 吐出孔からの薬液等の吐出を実現するには、 前 述したのと同様に、 当該吐出部材に連結される容器本体に圧を加えればよい 。 吐出操作終了後の弁体の復元に際して、 通気フィルタから無菌的に空気を 流入させ得ることや、 外気を流入させようとする陰圧によって変形を受けた 弁体の復元動作が加速されること (それゆえ弁体を逆止弁として作用させ得 ること) については、 前述の場合と同様である。 . 第 2の吐出部材において、 弁体の圧縮変形は通気フィルタの通液圧よりも 低い液圧によって達成されることから、 吐出操作の際に通気孔において液漏 れを生じることがない。 しかも、 吐出孔および Zまたは当該吐出孔につなが る吐出部内の流路の開放は、 通気フィルタへの外部からの通気圧では達成さ れないことから、 容器本体の復元時に通気孔ではなく吐出孔から外気が流入 したり、 これに伴って吐出孔から内容液が漏れ出したりすることがない。  In the second discharge member, in order to discharge a chemical solution or the like from the discharge holes, pressure may be applied to the container body connected to the discharge member, as described above. When the valve is restored after the discharge operation, the air can be aseptically introduced from the ventilation filter, and the restoration operation of the valve that has been deformed by the negative pressure that tries to allow the outside air to be accelerated ( Therefore, the fact that the valve body can act as a check valve) is the same as in the case described above. In the second discharge member, since the compression deformation of the valve body is achieved by a liquid pressure lower than the liquid pressure of the ventilation filter, liquid leakage does not occur in the ventilation hole during the discharge operation. In addition, since the opening of the discharge hole and Z or the flow passage in the discharge portion connected to the discharge hole cannot be achieved by the external ventilation pressure to the ventilation filter, the discharge hole is used instead of the ventilation hole when the container body is restored. There is no possibility that outside air flows in from the outlet or the contents liquid leaks out of the discharge holes.
従って、 本発明に係る第 2の吐出部材によれば、 吐出孔から吐出された液 体の逆流およびそれに伴う微生物や埃等の上流側への侵入を高度に防止しつ つ、 吐出処理と吐出操作後における容器の復元とをスムーズに行うことがで さる。  Therefore, according to the second discharge member of the present invention, the discharge process and discharge can be performed while preventing the liquid discharged from the discharge holes from flowing backward and invading microorganisms and dust to the upstream side. Restoration of the container after operation can be performed smoothly.
第 2の吐出部材において、 弁体は、 流路の閉鎖と開放とを厳密に行うとい う観点から、 吐出部の内表面に固定される。 そこで、 これに限定されるもの ではないが、 弁体と吐出部とは一体成形によって形成するのが好ましい。 弁 体と繋止部とを一体成形することによって、 両者を確実に固定するとともに In the second discharge member, the valve body is fixed to the inner surface of the discharge part from the viewpoint of strictly closing and opening the flow path. Therefore, although not limited thereto, it is preferable that the valve body and the discharge portion are formed by integral molding. By integrally molding the valve body and the locking part, both are securely fixed and
、 吐出部材の生産工程を効率化することができる。 弁体と吐出部とを一体成 3 009572 Thus, the production process of the discharge member can be made more efficient. The valve body and discharge section are integrated 3 009572
7 形する方法としては、 例えば多色成形ゃィンサート成形が挙げられる。  As a method of shaping, for example, multicolor molding insert molding can be mentioned.
(第 3の実施形態)  (Third embodiment)
本発明に係る第 3の吐出部材は、 底部に吐出孔を備える有底略筒状または 略椀状の吐出部と、 当該吐出部内に配置されて、 上記吐出孔側を下流側とし たときに上流側から液圧を受けていない状態で上記吐出孔または当該吐出孔 につながる流路を閉鎖し、 かつ上流側から液圧を受けると伸張変形して当該 吐出孔または流路を開放する、 弾性体からなる弁体と、 通気フィルタを介し て上記弁体よりも上流側の流路とつながる通気孔と、 を備え、 上記弁体の伸 張変形が上記通気フィルタの通液圧よりも小さい液圧によって達成されかつ 上記吐出孔または上記流路の開放が、 上記通気フィルタへの外部からの通気 圧では達成されないものであることを特徴とする。  A third discharge member according to the present invention includes a bottomed substantially cylindrical or bowl-shaped discharge portion having a discharge hole at a bottom portion, and a discharge portion disposed in the discharge portion, wherein the discharge hole side is a downstream side. Elasticity that closes the discharge hole or the flow path leading to the discharge hole without receiving the hydraulic pressure from the upstream side, and expands and deforms to open the discharge hole or the flow path when receiving the hydraulic pressure from the upstream side. A valve body comprising: a valve body; and a ventilation hole connected to a flow path upstream of the valve body via a ventilation filter, wherein the expansion deformation of the valve body is smaller than the hydraulic pressure of the ventilation filter. Pressure, and the opening of the discharge hole or the flow path is not achieved by an external ventilation pressure to the ventilation filter.
第 3の吐出部材において、 吐出部の内部に配置される弾性体からなる弁体 は、 吐出孔または流路の閉鎖と開放とを制御するものである。 この弁体は、 上流側から液圧を受けていない状態で吐出孔または吐出孔につながる流路を 閉鎖し、 上流側から液圧を受けると伸張変形を生じて、 当該吐出孔または流 路を開放する。 吐出孔または流路が開放される結果、 弁体の上流側と吐出孔 との流路が連通することとなって、 吐出孔からの薬液等の吐出を実現するこ とができる。  In the third discharge member, an elastic body disposed inside the discharge portion controls the closing and opening of the discharge hole or the flow path. This valve element closes the discharge hole or the flow path leading to the discharge hole without receiving the hydraulic pressure from the upstream side, and when receiving the hydraulic pressure from the upstream side, it expands and deforms, and the discharge hole or the flow path is closed. Open. As a result of the opening of the discharge hole or the flow path, the flow path between the upstream side of the valve body and the discharge hole is communicated, so that the discharge of the chemical solution or the like from the discharge hole can be realized.
第 3の吐出部材において、 吐出孔からの薬液等の吐出を実現するには、 前 述したのと同様に、 当該吐出部材に連結される容器本体に圧を加えればよい 。 吐出操作終了後の弁体の復元に際して、 通気フィルタから無菌的に空気を 流入させ得ることや、 外気を流入させようとする陰圧によって変形を受けた 弁体の復元動作が加速されること (それゆえ弁体を逆止弁として作用させ得 ること) については、 前述の場合と同様である。  In the third discharge member, in order to realize the discharge of the chemical solution or the like from the discharge holes, pressure may be applied to the container body connected to the discharge member, as described above. When the valve is restored after the discharge operation, the air can be aseptically introduced from the ventilation filter, and the restoration operation of the valve that has been deformed by the negative pressure that tries to allow the outside air to be accelerated ( Therefore, the fact that the valve body can act as a check valve) is the same as in the case described above.
第 3の吐出部材において、 弁体の伸張変形は通気フィルタの通液圧よりも 低い液圧によって達成されることから、 吐出操作の際に通気孔において液漏 れを生じることがない。 しかも、 かかる伸張変形は弁体の構造上、 外部から の圧によっては生じない (それゆえ、 通気フィルタの通気圧と同等の圧が外 部からかかっても、 伸張変形は達成されない) こと力ゝら、 容器本体の復元時 2 In the third discharge member, since the expansion deformation of the valve body is achieved by a liquid pressure lower than the liquid pressure of the ventilation filter, liquid leakage does not occur in the ventilation hole during the discharge operation. In addition, due to the structure of the valve body, such extension deformation is not caused by external pressure (thus, even if a pressure equivalent to the ventilation pressure of the ventilation filter is applied from the outside, the extension deformation is not achieved). When the container body is restored Two
8 に通気孔ではなく吐出孔から外気が流入したり、 これに伴って吐出孔から内 容液が漏れ出したりすることがない。  In Fig. 8, there is no outside air flowing through the discharge hole instead of the vent hole, and consequently, the content liquid does not leak out of the discharge hole.
従って、 本発明に係る第 3の吐出部材によれば、 吐出孔から吐出された液 体の逆流おょぴそれに伴う微生物や埃等の上流側への侵入を高度に防止しつ つ、 吐出処理と吐出操作後における容器の復元とをスムーズに行うことがで さる。  Therefore, according to the third discharge member of the present invention, the discharge processing is performed while preventing the liquid discharged from the discharge holes from flowing backward and invading microorganisms, dust and the like to the upstream side at a high level. And the restoration of the container after the discharge operation can be performed smoothly.
本発明に係る第 3の吐出部材において、 弁体は、 上記流路内に固定される 弁本体部と、 その吐出孔側先端における突起とを有するものであり、 弁本体 部先端の突起は、 吐出孔につながる流路の内壁に設けられた凸条にその下流 側から係合して、 当該流路を閉鎖するものであり、 かつ、  In the third discharge member according to the present invention, the valve body has a valve body fixed in the flow path and a protrusion at the discharge hole side end, and the protrusion at the valve body end is It engages with a ridge provided on the inner wall of the flow path connected to the discharge hole from the downstream side to close the flow path, and
弁本体部は、 上流側から液圧によって下流側に伸張変形して、 当該弁本体 部先端の突起と上記流路内壁における凸条との間に間隙を形成するものであ るのが好ましい。  Preferably, the valve body extends and deforms from the upstream side to the downstream side by hydraulic pressure to form a gap between the projection at the tip of the valve body and the ridge on the inner wall of the flow passage.
この場合、 弁体の弁本体部先端における突起は、 液圧を受けていない状態 で流路の内壁に設けられた凸条にその下流側から係合しており、 当該流路を 閉鎖している。 一方、 弁体は、 液圧を受けると当該係合位置よりも下流側に 伸張変形することから、 弁本体部先端の突起と、 流路内壁の凸条との間にお いて流路が開放される。 吐出操作を終えて弁体に液圧がかからなくなった後 においては、 弁体の復元によって弁本体部先端の突起が上流側に復帰するこ とから、 流路内壁の凸条と再び係合して、 流路が閉鎖される。 この弁体の復 元動作は、 前述のように、 吐出操作により変形した容器本体を復元させる際 に生じる、 外気を導入するための陰圧によって加速される。  In this case, the projection at the tip of the valve body portion of the valve body is engaged with the ridge provided on the inner wall of the flow path from the downstream side without receiving the hydraulic pressure, and the flow path is closed. I have. On the other hand, when the valve element receives the hydraulic pressure, it expands and deforms downstream from the engagement position, so that the flow path is opened between the projection at the end of the valve main body and the projection on the inner wall of the flow path. Is done. After the discharge operation is completed and the fluid pressure is no longer applied to the valve body, the projection at the tip of the valve body returns to the upstream side due to the restoration of the valve body, so it re-engages with the ridge on the inner wall of the flow passage Then, the flow path is closed. As described above, the restoration operation of the valve body is accelerated by the negative pressure for introducing outside air, which is generated when the container body deformed by the discharge operation is restored.
(第 4の実施形態)  (Fourth embodiment)
本発明に係る第 4の吐出部材は、 底部に吐出孔を備える有底略筒状または 略椀状の吐出部と、 当該吐出部の外表面側から当接して、 上記吐出孔側を下 流側としたときに上流側から液圧を受けていない状態で上記吐出孔を閉鎖し 、 かつ上流側から液圧を受けると伸張変形して当該吐出孔を開放する、 弾性 体からなる弁体と、 通気フィルタを介して上記吐出孔とつながる通気孔と、 を備え、 当該弁体の伸張変形が上記通気フィルタの通液圧よりも小さい液圧 によつて達成されかつ上記吐出孔の開放が、 上記通気フィルタへの外部から の通気圧では達成されないものであることを特徴とする。 The fourth discharge member according to the present invention is configured such that the fourth discharge member abuts from the outer surface side of the bottom substantially cylindrical or bowl-shaped discharge portion having a discharge hole at the bottom, and flows down the discharge hole side. A valve body made of an elastic body that closes the discharge hole in a state where it is not receiving the hydraulic pressure from the upstream side when receiving the hydraulic pressure from the upstream side, and expands and deforms to open the discharge hole when receiving the hydraulic pressure from the upstream side. And a ventilation hole connected to the discharge hole via a ventilation filter, wherein a hydraulic pressure in which the expansion deformation of the valve body is smaller than the hydraulic pressure of the ventilation filter And the opening of the discharge hole is not achieved by an external ventilation pressure to the ventilation filter.
第 4の吐出部材において、 吐出部の外表面側から吐出孔に当接する弾性体 からなる弁体は、 吐出孔の閉鎖と開放とを制御するものである。 この弁体は 、 上流側から液圧を受けていない状態で吐出孔を閉鎖し、 上流側から液圧を 受けると吐出部の外側 (下流側) に伸張変形を生じて (その結果、 弁体が吐 出部の外側に橈んで) 、 当該吐出孔を開放する。 吐出孔が開放される結果、 弁体の上流側と吐出孔との流路が連通することとなって、 吐出孔からの薬液 等の吐出を実現することができる。  In the fourth discharge member, a valve body made of an elastic body that comes into contact with the discharge hole from the outer surface side of the discharge part controls closing and opening of the discharge hole. This valve body closes the discharge hole in a state where it is not receiving the hydraulic pressure from the upstream side, and when it receives the hydraulic pressure from the upstream side, it expands and deforms outside the discharge part (downstream side) (as a result, the valve body Radiate to the outside of the discharge section) to open the discharge hole. As a result of the opening of the discharge hole, the flow path between the upstream side of the valve body and the discharge hole communicates, and the discharge of the chemical solution or the like from the discharge hole can be realized.
第 4の吐出部材において、 吐出孔からの薬液等の吐出を実現するには、 前 述したのと同様に、 当該吐出部材に連結される容器本体に圧を加えればよレ.、 。 吐出操作終了後の弁体の復元に際して、 通気フィルタから無菌的に空気を 流入させ得ることや、 外気を流入させようとする陰圧によつて変形を受けた 弁体の復元動作が加速されること (それゆえ弁体を逆止弁として作用させ得 ること) については、 前述の場合と同様である。  In the fourth discharge member, in order to realize the discharge of the chemical solution or the like from the discharge holes, similarly as described above, pressure may be applied to the container body connected to the discharge member. When the valve is restored after the end of the discharge operation, the air can be aseptically introduced from the ventilation filter, and the restoration operation of the valve that has been deformed by the negative pressure that tries to let in the outside air is accelerated. (Thus, the valve element can be made to act as a check valve) is the same as the case described above.
第 4の吐出部材において、 弁体の伸張変形は通気フィルタの通液圧よりも 低 ヽ液圧によって達成されることから、 吐出操作の際に通気孔におレ、て液漏 れを生じることがない。 しかも、 かかる伸張変形は弁体の構造上、 外部から の圧によっては生じない (それゆえ、 通気フィルタの通気圧と同等の圧が外 部からかかっても、 伸張変形は達成されない) ことから、 容器本体の復元時 に通気孔ではなく吐出孔から外気が流入したり、 これに伴って吐出孔から内 容液が漏れ出したりすることがない。  In the fourth discharge member, since the expansion deformation of the valve body is achieved by the liquid pressure lower than the liquid pressure of the ventilation filter, the liquid may leak to the ventilation hole during the discharge operation. There is no. Moreover, such an expansion deformation does not occur due to an external pressure due to the structure of the valve body (thus, even if a pressure equivalent to the ventilation pressure of the ventilation filter is applied from the outside, the expansion deformation is not achieved). When the container body is restored, no outside air flows through the discharge hole instead of the vent hole, and accordingly, the content liquid does not leak from the discharge hole.
従って、 本発明に係る第 4の吐出部材によれば、 吐出孔から吐出された液 体の逆流およびそれに伴う微生物や埃等の上流側への侵入を高度に防止しつ つ、 吐出処理と吐出操作後における容器の復元とをスムーズに行うことがで さる。  Therefore, according to the fourth discharge member of the present invention, the discharge process and the discharge process can be performed while preventing the backflow of the liquid discharged from the discharge hole and the accompanying invasion of microorganisms and dust to the upstream side. Restoration of the container after operation can be performed smoothly.
本発明に係る第 4の吐出部材において、 吐出孔は、 上記吐出部内に固定さ れる略円盤状の弁座と、 当該弁座を保持する吐出部内壁面とによって区画さ れてなるものであり、 弁体は、 略環状の薄肉部を有するものでありかつ当該 薄肉部を上記吐出部の外表面側から上記弁座に当接させて吐出孔を閉鎖する ものであり、 弁体の薄肉部は、 吐出孔側を下流側としたときに、 液圧によつ て下流側に伸張変形して、 当該吐出孔を開放するものであるのが好ましい。 この場合、 弁体は、 液圧を受けていない状態で、 その薄肉部を略円盤状の 弁座に当接させることによって、 吐出孔を閉鎖させている。 弁体は、 液圧を 受けると下流側に伸張変形する (吐出部の外側に橈む) ことから、 略円盤状 の弁座と、 当該弁座を保持する吐出部内壁面との間に区画される吐出孔が開 放される。 吐出操作を終えて弁体に液圧がかからなくなった後においては、 再び弁体の薄肉部が略円盤状の弁座に当接することから、 流路が閉鎖される 。 この弁体の復元動作は、 前述のように、 吐出操作により変形した容器本体 を復元させる際に生じる、 外気を導入するための陰圧によって加速される。 本発明に係る第 4の吐出部材において、 弁体は、 吐出部の外側に一体成形 されてなるものであるのが好ましい。 この場合、 吐出部材の生産を効率よく 行うことができる。 弁体と吐出部との一体成形の方法は特に限定されるもの ではなく、 多色成形やインサート成形等の種々の方法を採用することができ る。 In the fourth discharge member according to the present invention, the discharge hole is defined by a substantially disk-shaped valve seat fixed in the discharge portion and a discharge portion inner wall surface that holds the valve seat. The valve element has a substantially annular thin portion and The thin portion is brought into contact with the valve seat from the outer surface side of the discharge portion to close the discharge hole, and the thin portion of the valve body is driven by hydraulic pressure when the discharge hole side is downstream. Then, it is preferable that the discharge hole is expanded and deformed downstream to open the discharge hole. In this case, the discharge hole of the valve body is closed by contacting a thin portion of the valve body with a substantially disk-shaped valve seat in a state where the valve body is not subjected to hydraulic pressure. The valve element expands and deforms downstream when receiving the hydraulic pressure (radiates outward from the discharge portion), and is partitioned between the substantially disc-shaped valve seat and the inner wall surface of the discharge portion holding the valve seat. Discharge holes are opened. After the discharge operation is completed and the hydraulic pressure is no longer applied to the valve element, the flow path is closed because the thin portion of the valve element again contacts the substantially disk-shaped valve seat. As described above, the restoration operation of the valve body is accelerated by the negative pressure for introducing outside air, which is generated when the container body deformed by the discharge operation is restored. In the fourth discharge member according to the present invention, it is preferable that the valve body is formed integrally with the outside of the discharge part. In this case, the production of the discharge member can be performed efficiently. The method of integrally molding the valve body and the discharge portion is not particularly limited, and various methods such as multicolor molding and insert molding can be adopted.
(第 5の実施形態)  (Fifth embodiment)
本発明に係る第 5の吐出部材は、 底部に孔を備える有底略筒状または略椀 状の吐出部と、 略環状の弁本体部とその先端に設けられた略環状の薄肉部と を有しかつ当該薄肉部を上記孔から吐出部外に露出した状態で、 当該弁本体 部を吐出部内に固定してなる、 弾性体からなる弁体と、 当該吐出部内に配置 されて、 上記弁体とともに吐出孔を区画してなる円柱状の弁体支持部と、 上 記吐出孔側を下流側としたときに、 通気フィルタを介して上記弁体よりも上 流側の流路につながる通気孔と、 を備え、 上記弁体が、 上流側から ί夜圧を受 けていない状態で、 その薄肉部を弁体支持部の外周面に当接させて上記吐出 孔を閉鎖し、 かつ上流側から液圧を受けると当該薄肉部を伸張変形させて当 該吐出孔を開放するものであり、 上記薄肉部の伸張変形が上記通気フィルタ の通液圧よりも小さい液圧によって達成されかつ上記吐出孔の開放が、 上記 通気フィルタへの外部からの通気圧では達成されないものであることを特徴 とする。 A fifth discharge member according to the present invention includes a substantially cylindrical bottomed or substantially bowl-shaped discharge portion having a hole at the bottom, a substantially annular valve body, and a substantially annular thin portion provided at the tip thereof. A valve body made of an elastic body, wherein the valve body portion is fixed in the discharge portion while the thin portion is exposed to the outside of the discharge portion from the hole, and the valve is disposed in the discharge portion, and the valve is disposed in the discharge portion. A cylindrical valve body support portion that defines a discharge hole together with a body, and a flow passage that is connected to a flow path upstream of the valve body through a ventilation filter when the discharge hole side is a downstream side. The valve body is closed to the outer peripheral surface of the valve body supporting portion while the night time pressure is not received from the upstream side, and the discharge hole is closed. When receiving the liquid pressure from the side, the thin portion is stretched and deformed to open the discharge hole. And the opening of the discharge hole is not achieved by an external ventilation pressure to the ventilation filter. And
第 5の吐出部材において、 吐出部の内部に配置される弾性体からなる弁体 は、 その薄肉部を、 吐出部の底部に設けられた孔から吐出部外に露出した状 態で固定され、 上記弁体支持部材との間に吐出孔を区画している。 この薄肉 部は、 弁体支持部材における円柱状の弁体支持部を弁座として、 吐出孔の閉 鎖と開放とを制御するものである。 すなわち、 弁体の薄肉部は、 上流側から 液圧を受けていない状態で弁体支持部の外周面に当接し、 これによつて吐出 孔を閉鎖する。 一方、 上流側から液圧を受けると、 その薄肉部において、 吐 出部の外側 (下流側) に伸張変形を生じて (その結果、 弁体が弁体支持部の 外周側に橈んで) 、 これによつて吐出孔を開放する。 吐出孔が開放される結 果、 弁体の上流側と吐出孔との流路が連通することとなって、 吐出孔からの 薬液等の吐出を実現することができる。  In the fifth discharge member, the valve body made of an elastic body disposed inside the discharge part is fixed in a state where its thin portion is exposed to the outside of the discharge part from a hole provided at the bottom of the discharge part, A discharge hole is defined between the valve body support member and the valve body support member. The thin-walled portion controls closing and opening of the discharge hole by using the cylindrical valve body support portion of the valve body support member as a valve seat. That is, the thin-walled portion of the valve body contacts the outer peripheral surface of the valve body support portion without receiving the hydraulic pressure from the upstream side, thereby closing the discharge hole. On the other hand, when receiving the hydraulic pressure from the upstream side, the thin portion undergoes extension deformation outside the discharge portion (downstream side) (as a result, the valve element radially extends to the outer peripheral side of the valve element support portion), As a result, the discharge hole is opened. As a result of the opening of the discharge hole, the flow path between the upstream side of the valve body and the discharge hole communicates, and the discharge of a chemical solution or the like from the discharge hole can be realized.
第 5の吐出部材において、 吐出孔からの薬液等の吐出を実現するには、 前 述したのと同様に、 当該吐出部材に連結される容器本体に圧を加えればよ 、 。 吐出操作終了後の弁体の復元に際して、 通気フィルタから無菌的に空気を 流入させ得ることや、 外気を流入させようとする陰圧によって変形を受けた 弁体の復元動作が加速されること (それゆえ弁体を逆止弁として作用させ得 ること) については、 前述の場合と同様である。  In the fifth discharge member, in order to discharge a chemical solution or the like from the discharge holes, pressure may be applied to the container body connected to the discharge member in the same manner as described above. When the valve is restored after the discharge operation, the air can be aseptically introduced from the ventilation filter, and the restoration operation of the valve that has been deformed by the negative pressure that tries to allow the outside air to be accelerated ( Therefore, the fact that the valve body can act as a check valve) is the same as in the case described above.
第 5の吐出部材において、 弁体の伸張変形は通気フィルタの通液圧よりも 低い液圧によって達成されることから、 吐出操作の際に通気孔において液漏 れを生じることがない。 しかも、 かかる伸張変形は弁体の構造上、 外部から の圧によっては生じない (それゆえ、 通気フィルタの通気圧と同等の圧が外 部からかかっても、 伸張変形は達成されない) ことから、 容器本体の復元時 に通気孔ではなく吐出孔から外気が流入したり、 これに伴って吐出孔から内 容液が漏れ出したりすることがない。  In the fifth discharge member, since the expansion deformation of the valve body is achieved by a liquid pressure lower than the liquid pressure of the ventilation filter, liquid leakage does not occur in the ventilation hole during the discharge operation. Moreover, such an expansion deformation does not occur due to an external pressure due to the structure of the valve body (thus, even if a pressure equivalent to the ventilation pressure of the ventilation filter is applied from the outside, the expansion deformation is not achieved). When the container body is restored, no outside air flows through the discharge hole instead of the vent hole, and accordingly, the content liquid does not leak from the discharge hole.
従って、 本発明に係る第 5の吐出部材によれば、 吐出孔から吐出された液 体の逆流およびそれに伴う微生物や埃等の上流側への侵入を高度に防止しつ つ、 吐出処理と吐出操作後における容器の復元とをスムーズに行うことがで きる。 9572 Therefore, according to the fifth discharge member of the present invention, the discharge processing and the discharge are performed while preventing the liquid discharged from the discharge hole from flowing backward and the microorganisms and dust accompanying the discharge from entering the upstream side to a high degree. Restoration of the container after the operation can be performed smoothly. 9572
12 本発明に係る第 5の吐出部材においては、 弁体支持部がその円柱部分の上 流側にフランジ部を有しており、 弁体の弁本体部が、 液圧を受けていない状 態で上記フランジ部に当接して流路を閉鎖するものであり、 かつ液圧を受け ると圧縮変形して弁体支持部との間に流路を開放するものであるのが好まし レ、。  12 In the fifth discharge member according to the present invention, the valve body supporting portion has a flange on the upstream side of the cylindrical portion, and the valve body of the valve body is not subjected to the hydraulic pressure. It is preferable that the flow path is closed by abutting on the above-mentioned flange portion, and that the flow path is opened between the valve body support portion and a compressive deformation when subjected to hydraulic pressure. .
この場合、 弁体は、 上流側から液圧を受けていない状態で、 その薄肉部を 弁体支持部の外周面に当接させて吐出孔を閉鎖させるだけではなく、 さらに 、 弁本体部を弁体支持部のフランジ部に当接させることによって流路を閉鎖 させている。 従って、 吐出孔の閉鎖をより一層確実に行なうことができる。 一方、 弁体が上流側から液圧を受けると、 その薄肉部において吐出部の外側 (下流側) に伸張変形を生じさせるだけでなく、 さらに、 弁本体部を圧縮変 形させて、 弁体支持部のフランジ部とのに流路を形成 (開放) する。 こうし て吐出孔および流路が開放される結果、 弁体の上流側と吐出孔との流路が連 通することとなって、 吐出孔からの薬液等の吐出を実現することができる。 上記第 5の吐出部材およびその好適態様において、 吐出操作を終えて弁体 に液圧がかからなくなった後でのその復元動作は、 前述のように、 吐出操作 により変形した容器本体を復元させる際に生じる、 外気を導入するための陰 圧によって加速される。  In this case, in a state where the valve body is not receiving the hydraulic pressure from the upstream side, not only is the thin portion abutted on the outer peripheral surface of the valve body support portion to close the discharge hole, but also the valve body portion is closed. The channel is closed by making contact with the flange of the valve body support. Therefore, the discharge hole can be more reliably closed. On the other hand, when the valve element receives hydraulic pressure from the upstream side, not only does the thin wall portion expand and deform outside the discharge section (downstream side), but also the valve body section is compressed and deformed, and the valve element is compressed and deformed. A flow path is formed (opened) with the flange of the support. As a result, the discharge hole and the flow path are opened, so that the flow path between the upstream side of the valve body and the discharge hole communicates with each other, so that the discharge of the chemical solution or the like from the discharge hole can be realized. In the fifth discharge member and the preferred embodiment thereof, the restoring operation after the discharge operation is completed and the liquid pressure is not applied to the valve body restores the container body deformed by the discharge operation as described above. It is accelerated by the negative pressure that is introduced when introducing outside air.
本発明に係る第 5の吐出部材において、 弁体の弁本体部は、 吐出部の内表 面とが一体化するように成形したものであるのが好ましい。 この場合、 吐出 部材の生産を効率よく行うことができる。 弁体と吐出部との一体成形の方法 は特に限定されるものではなく、 多色成形ゃィンサート成形等の種々の方法 を採用することができる。  In the fifth discharge member according to the present invention, it is preferable that the valve body of the valve body is formed so as to be integrated with the inner surface of the discharge part. In this case, the production of the discharge member can be performed efficiently. The method of integrally molding the valve body and the discharge portion is not particularly limited, and various methods such as multicolor molding insert molding can be employed.
〔抗菌処理〕  (Antibacterial treatment)
本発明に係る吐出部材において、 弁体および/または吐出孔は抗菌処理を 施したものであるのが好ましい。 弁体および/または吐出孔に抗菌処理を施 した場合には、 吐出操作の終了後に吐出孔の近傍で滞留する内容液 (残留液 ) に対して、 細菌の繁殖等を防止する作用を発揮させることができる。  In the discharge member according to the present invention, it is preferable that the valve body and / or the discharge hole have been subjected to antibacterial treatment. When antibacterial treatment is applied to the valve body and / or the discharge port, it exerts an effect of preventing the growth of bacteria and the like against the content liquid (residual liquid) staying near the discharge port after the end of the discharge operation. be able to.
抗菌処理の対象は、 吐出部材の構成に応じて適宜選定すればよく、 吐出部 全体、 弁座、 容器本体、 吐出部を覆うキャップの表面 (特に、 吐出部と接触 する内表面) 、 当該キャップの内部に配置される吸水材 (スポンジ、 布、 紙 、 ヒドロゲル等) などの種々の部位を挙げることができるが、 特に限定され るものではない。 The target of the antibacterial treatment may be appropriately selected according to the configuration of the discharge member. Various types such as the whole, valve seat, container body, the surface of the cap that covers the discharge part (particularly the inner surface that comes into contact with the discharge part), and the water-absorbing material (sponge, cloth, paper, hydrogel, etc.) placed inside the cap However, the site is not particularly limited.
抗菌処理は、 例えば弁体等を形成する熱可塑性エラストマ一等の弾性材料 ;吐出部、 吐出孔、 弁座等を形成するための樹脂材料;上記吸収材の形成材 料などにあらかじめ防腐剤、 抗菌剤等の薬剤を配合したり、 あらかじめ成形 された弁体や吐出部等の表面に上記薬剤を塗付等の手段によって付着させた り、 あるいは弁体、 吐出部、 キャップ、 キャップ内の吸収材等の形成材料に シランカツプリングゃセレニウムコーティング等の表面処理を施したりする ことにより、 達成される。 (メタ) アクリルアミ ド系等の高分子と水膨潤性 粘土鉱物とを組み合わせてなるヒ ドロゲルに対しては、 その表面にセレユウ ムをコーティングすることで抗菌処理を施すことができる。  The antibacterial treatment includes, for example, an elastic material such as a thermoplastic elastomer that forms a valve body; a resin material for forming a discharge portion, a discharge hole, a valve seat, and the like; a preservative, A drug such as an antibacterial agent is blended, the above-mentioned drug is adhered to the surface of a preformed valve body or a discharge portion by coating or the like, or is absorbed in a valve body, a discharge portion, a cap, or a cap. This can be achieved by subjecting a material such as a material to a surface treatment such as silane coupling / selenium coating. Antimicrobial treatment can be applied to the hydrogel, which is a combination of a polymer such as (meth) acrylamide and a water-swellable clay mineral, by coating the surface with selenium.
〔通液フィルタ〕  [Liquid filter]
本発明に係る吐出部材は、 吐出孔よりも上流側、 または弁体による流路の 開閉位置よりも上流側に通液フィルタを備えるのが好ましい。 通液フィルタ を設けることによって、 万一、 吐出部の吐出孔近傍に残留する液中に微生物 、 埃等が浸入するという事態が生じたとしても、 当該残留液が吐出部材に連 結される容器本体にまで侵入 (逆流) するという事態については、 これを抑 制または防止することができる。 すなわち、 通液フィルタを設けることは、 吐出部材に接続された容器等への汚染物質の侵入を抑制または防止するとい う観点から好適である。  The discharge member according to the present invention is preferably provided with a liquid passage filter upstream of the discharge hole or upstream of the opening / closing position of the flow path by the valve element. Even if a situation in which microorganisms, dust and the like enter the liquid remaining in the vicinity of the discharge port of the discharge part due to the provision of the liquid passage filter occurs, the residual liquid is connected to the discharge member. In the event of intrusion (backflow) into the main body, this can be suppressed or prevented. That is, providing a liquid passage filter is preferable from the viewpoint of suppressing or preventing intrusion of contaminants into a container or the like connected to the discharge member.
通液フィルタが、 例えば孔径 0 . 2〜0 . 4 5 / m程度の (小孔径の) も のである場合には、 懸濁液を収容する容器に本発明の吐出部材を適用するの が困難になる。 その一方で、 万一、 微生物、 埃等を含む残留液が吐出孔から 逆流するという事態が生じたとしても、 当該残留液が本発明の吐出部材に連 結される容器本体にまで侵入 (逆流) する事態を確実に防止または抑制する ことができる。  When the liquid passage filter has a pore diameter of, for example, about 0.2 to 0.45 / m (small pore diameter), it is difficult to apply the discharge member of the present invention to a container containing a suspension. become. On the other hand, even in the event that a residual liquid containing microorganisms, dust, and the like flows back from the discharge hole, the residual liquid enters the container body connected to the discharge member of the present invention (backflow). ) Can be reliably prevented or suppressed.
通液フィルタが、 例えば孔径 1 0 ~ 2 0 πι程度の (比較的大孔径の) も 3 009572 If the filter has a pore size of, for example, about 10 to 20 πι (with a relatively large pore size) 3 009572
14 のである場合には、 懸濁液を収容する容器にも本発明の吐出部材を適用する ことができる。 この場合において、 懸濁液による通液フィルタの目詰まりを 考慮する必要はなく、 むしろ懸濁液の成分が吐出孔の近傍で沈殿するのを抑 制するという新たな効果を得ることができる。 また、 かかる孔径の大きな通 液フィルタであっても、 微生物等の通過をある程度抑制することが可能であ ることから、 万一、 微生物等を含む残留液が吐出孔から逆流するという事態 が生じたとしても、 当該残留液が容器本体にまで侵入 (逆流) するという事 態を抑止することについて一定の効果を得ることができる。  In the case of 14, the discharge member of the present invention can be applied to a container for storing the suspension. In this case, it is not necessary to consider clogging of the liquid passage filter due to the suspension, but rather, a new effect of suppressing the components of the suspension from settling near the discharge port can be obtained. In addition, even with such a liquid filter having a large pore diameter, the passage of microorganisms and the like can be suppressed to some extent, so that a residual liquid containing microorganisms and the like may flow backward from the discharge hole. Even if this is the case, a certain effect can be obtained in suppressing the situation where the residual liquid enters (backflows) into the container body.
〔容器〕  (Container)
上記課題を解決するための本発明の容器は、 本発明に係る吐出部材を容器 本体の口部に備えるものである。 本発明の容器は、 例えば点眼液を収容する 点眼容器として好適である。 発明を実施するための最良の形態  A container of the present invention for solving the above-mentioned problems is provided with a discharge member according to the present invention at an opening of a container body. The container of the present invention is suitable, for example, as an ophthalmic container for storing an ophthalmic solution. BEST MODE FOR CARRYING OUT THE INVENTION
次に、 本発明の吐出部材およびそれを備える容器について、 図面を参照し つつ詳細に説明する。  Next, the discharge member of the present invention and a container including the same will be described in detail with reference to the drawings.
〔第 1の吐出部材および容器〕  [First discharge member and container]
本発明に係る第 1の吐出部材 1 0は、 例えば図 1に示すように、 底部に吐 出孔 1 2を備える有底略筒状 (または略椀状) の吐出部 1 1と、 吐出部 1 1 の内部に配置されて、 上流側 Uから液圧を受けていない状態で吐出孔 1 2を 閉鎖し上流側 Uから液圧を受けると圧縮変形して吐出孔 1 2を開放する弁体 1 3と、 吐出部 1 1の内部に配置されて吐出部の内表面 1 1 dとの間に流路 1 5を区画しかつ上流側 Uにおいて弁体 1 3を固定する繋止部 1 4と、 通気 フィルタ 1 7を介して弁体 1 3よりも上流側の流路につながる通気孔 1 6と 、 を備えている。  For example, as shown in FIG. 1, the first discharge member 10 according to the present invention includes a bottomed substantially cylindrical (or substantially bowl-shaped) discharge portion 11 having a discharge hole 12 at the bottom, and a discharge portion. 11 A valve element that is disposed inside 1 and closes the discharge port 12 when it is not receiving hydraulic pressure from the upstream side U, and compresses and deforms when it receives hydraulic pressure from the upstream side U to open the discharge port 12. A locking portion 1 4 that defines a flow path 15 between 13 and an inner surface 1 1 d of the discharging portion that is disposed inside the discharging portion 11 and that fixes the valve element 13 on the upstream side U. And a ventilation hole 16 connected to a flow path on the upstream side of the valve body 13 via the ventilation filter 17.
吐出孔 1 2は、 通常、 弁体 1 3によって閉鎖されているが、 流路 1 5を通 じて上流側 Uから弁体 1 3に液圧がかかると、 当該弁体 1 3に圧縮変形が生 じて、 吐出部 1 1の吐出孔 1 2と弁体 1 3との間に空隙が生じる。 これによ り、 当該空隙を通じて内容液を吐出することができる。 弁体 1 3は、 繋止部 1 4によって吐出部材 1 0中に固定されており、 繋止 部 1 4と吐出部の内表面 1 1 dとの間は、 薬液等の流路 1 5となっている。 吐出部 1 1は、 通気孔 1 6に通気フィルタ 1 7を配置する必要上、 吐出孔 1 2を備える吐出部本体 1 1 aと、 その上流側 Uに配置されて薬液容器等の 口部に接続される連結部 1 1 bとの 2つの部材からなつている。 吐出部本体 1 1 aと連結部 1 1 bとは、 接続部分 1 1 cに通気フィルタ 1 7を挟んだ状 態で、 超音波接着等の接合手段によって一体化される。 The discharge hole 12 is normally closed by the valve 13, but when hydraulic pressure is applied to the valve 13 from the upstream side U through the flow path 15, the valve 13 is compressed and deformed. As a result, a gap is generated between the discharge hole 12 of the discharge portion 11 and the valve body 13. This allows the content liquid to be discharged through the gap. The valve body 13 is fixed in the discharge member 10 by a locking portion 14, and between the locking portion 14 and the inner surface 11 d of the discharge portion, a flow path 15 of a chemical solution or the like is formed. Has become. Since the discharge section 11 needs to be provided with the ventilation filter 17 in the ventilation hole 16, the discharge section main body 11 a having the discharge hole 12 and the upstream section U are provided at the mouth of a chemical solution container or the like. It is made up of two members, the connecting part 1 1b to be connected. The discharge portion main body 11a and the connecting portion 11b are integrated by a joining means such as ultrasonic bonding with the ventilation filter 17 sandwiched between the connecting portions 11c.
第 1の吐出部材 1 0は、 例えば図 2に示すように、 容器本体 2 1の口部に 取り付けることによって用いられる。 図 2に示す容器 2 0では、 吐出部材 1 0は、 内栓 2 3を介して容器 2 0の首部 2 2に取り付けられている。 内栓 2 3は、 図 2および図 3に示すように、 容器 2 0の首部 2 2に摺動自在に挿嵌 されるものであって、 図 2は、 容器 2 0の使用状態における断面を示してお り、 図 3は、 容器 2 0の未開栓状態における断面図を示している。  The first discharge member 10 is used by being attached to the mouth of the container body 21 as shown in FIG. 2, for example. In the container 20 shown in FIG. 2, the discharge member 10 is attached to the neck 22 of the container 20 via the inner plug 23. The inner plug 23 is slidably inserted into the neck 22 of the container 20 as shown in FIGS. 2 and 3, and FIG. 2 is a cross-sectional view of the container 20 in use. FIG. 3 shows a sectional view of the container 20 in an unopened state.
図 3に示す未開栓状態では、 吐出部 1 1にキャップ 2 6が取り付けられて いるだけでなく、 吐出部材 1 0と容器本体 2 1との間にストッパー 2 7が冠 着されている。 これにより、 吐出部材 1 0は、 容器本体 2 1に対して浅く揷 嵌された状態となっている。 さらに、 この状態で内栓 2 3の先端部 2 3 aは 、 吐出部材 1 0の内表面に設けられたフランジ 1 9に当接している。 その結 果、 当該フランジ 1 9と内栓 2 3の先端部 2 3 aとによって吐出部材 1 0の 流路 1 5が分断されることとなり、 容器本体 2 1内に収容される内容液の無 菌状態をより高度に維持したり、 内容液の劣化 (空気酸化等) の進行を防止 したりすることができる。  In the unopened state shown in FIG. 3, not only the cap 26 is attached to the discharge portion 11 but also a stopper 27 is mounted between the discharge member 10 and the container body 21. Thus, the discharge member 10 is in a state of being shallowly fitted to the container body 21. Further, in this state, the distal end portion 23 a of the inner plug 23 is in contact with the flange 19 provided on the inner surface of the discharge member 10. As a result, the flow path 15 of the discharge member 10 is divided by the flange 19 and the distal end portion 23 a of the inner plug 23, and there is no empty liquid contained in the container body 21. It can maintain the bacterial state at a higher level and prevent the deterioration of the content liquid (air oxidation, etc.).
本発明に係る第 1の吐出部材およびそれを備える容器による吐出操作の一 連の工程を図 4および図 5に示す。 図 4 (a) は容器本体 2 1に圧を加えてい ない状態を示しており、 この状態で、 吐出部材の弁体 1 3は吐出孔 1 2を閉 鎖している。 それゆえ、 容器本体 2 1に収容された内容液 2 4は吐出部 1 1 から吐出されることなく、 容器本体 2 1および吐出部材内に留まる。 図 4 (b ) は容器本体 2 1に圧を加えた状態を示している。 この状態では、 吐出部材 の弁体 1 3に上流側 Uから内容液 2 4による液圧がかかっており、 これによ つて弁体 1 3が圧縮変形することから、 吐出孔 1 2が開放されて、 内容液 2 4が液滴 2 5として吐出される。 FIGS. 4 and 5 show a series of steps of the discharging operation using the first discharging member according to the present invention and the container provided with the first discharging member. FIG. 4 (a) shows a state in which no pressure is applied to the container body 21. In this state, the valve 13 of the discharge member closes the discharge hole 12. Therefore, the content liquid 24 stored in the container body 21 is not discharged from the discharge part 11 and stays in the container body 21 and the discharge member. FIG. 4B shows a state where pressure is applied to the container body 21. In this state, the liquid pressure of the content liquid 24 is applied to the valve body 13 of the discharge member from the upstream side U. Thus, since the valve element 13 is compressed and deformed, the discharge hole 12 is opened, and the content liquid 24 is discharged as a droplet 25.
図 5 (a) は、 図 4 (b) に示す状態の続きであって、 容器本体 2 1に対する 加圧を停止した状態を示している。 この状態で、 吐出部材の弁体 1 3には内 容液 2 4による液圧がかからなくなることから、 弁体 1 3が加圧前の形状に 復元して、 再び吐出孔 1 2が閉鎖される。 さらに、 図 5 (b) は、 図 5 (a) に 示す状態の続きであって、 容器本体 2 1に対する加圧を停止することで、 容 器本体 2 1が加圧前の形状に復元しようとしている状態を示している。 この 状態で吐出部材の弁体 1 3は吐出孔 1 2を閉鎖していることから、 容器本体 2 1への外気の流入は、 もっぱら通気孔 1 6を介して実現される。  FIG. 5 (a) is a continuation of the state shown in FIG. 4 (b), and shows a state in which pressurization of the container body 21 is stopped. In this state, the valve body 13 of the discharge member is no longer subjected to the liquid pressure due to the content liquid 24, and the valve body 13 is restored to the shape before pressurization, and the discharge hole 12 is closed again. Is done. Further, FIG. 5 (b) is a continuation of the state shown in FIG. 5 (a). By stopping the pressurization of the container main body 21, the container main body 21 tries to restore the shape before pressurization. Is shown. In this state, the valve member 13 of the discharge member closes the discharge hole 12, so that the outside air flows into the container body 21 exclusively through the vent hole 16.
図 6に示す、 第 1の吐出部材 1 0, およびそれを備える容器 2 0 ' につい ての他の実施形態においては、 吐出孔 1 2へとつながる流路 1 5上に通液フ ィルタ 1 8が設けられている。 従って、 前述のように、 万一、 微生物、 埃等 を含む残留液が吐出孔 1 2から逆流するという事態が生じたとしても、 当該 残留液が吐出部材 1 0 ' に連結される容器本体 2 1にまで侵入 (逆流) する 事態を抑制または防止することができる。  In another embodiment of the first discharge member 10 and the container 20 ′ including the first discharge member 10 shown in FIG. 6, a liquid filter 18 is provided on a flow path 15 connected to the discharge hole 12. Is provided. Therefore, as described above, even in the event that a residual liquid containing microorganisms, dust, and the like flows back from the discharge port 12, the residual liquid is connected to the discharge member 10 ′. It is possible to suppress or prevent intrusion (backflow) up to 1.
本発明に係る第 1の吐出部材は、 例えばその弁体 1 3 a, 1 3 bが、 図 7 および図 8に示すような断面形状を備えるものであってもよい。 すなわち、 図 7に示す吐出部材 1 0 aのように、 吐出孔 1 2にて露出している弁体 1 3 aの先端部分が平坦であってもよく、 図 8に示す吐出部材 1 0 bのように、 弁体 1 3 bがその先端に窪み 1 3 cを備えていてもよい。 特に、 図 8に示す 形状の弁体 1 3 bは、 上流 U側から液圧を受けた場合に、 窪み a 3 cを備え ていない弁体 (図 1や図 7に示す弁体 1 3, 1 3 a ) に比べて圧縮変形が生 じ易く (すなわち吐出孔 1 2を開放させ易く) 、 しかも吐出部 1 1の外部か らの圧によって吐出孔 1 2が開放するという問題が生じにくいことから、 吐 出操作をスムーズなものとし、 かつ逆流を防止するという点で好ましい。  In the first discharge member according to the present invention, for example, the valve bodies 13a and 13b may have a cross-sectional shape as shown in FIG. 7 and FIG. That is, as in the discharge member 10a shown in FIG. 7, the tip of the valve body 13a exposed at the discharge hole 12 may be flat, and the discharge member 10b shown in FIG. As shown in the above, the valve body 13b may have a depression 13c at its tip. In particular, the valve element 13 b having the shape shown in FIG. 8 is not provided with the depression a 3 c when receiving the hydraulic pressure from the upstream U side (the valve elements 13 and 13 shown in FIGS. 1 and 7). Compared to 13 a), compression deformation is more likely to occur (that is, the discharge hole 12 is easily opened), and the problem that the discharge hole 12 is opened by pressure from the outside of the discharge portion 11 is less likely to occur. Therefore, it is preferable in that the discharge operation is made smooth and the backflow is prevented.
〔第 2の吐出部材および容器〕  [Second discharge member and container]
本発明に係る第 2の吐出部材 3 0は、 例えば図 9 (断面図) および図 1 0 (分解断面図) に示すように、 底部に吐出孔 3 2を備える有底略筒状の吐出 部 3 1と、 吐出部 3 1の内部に配置されてなる、 リング状の弁体 3 3と、 吐 出部 3 1の開口端 3 1 d側から冠着されて、 吐出孔 3 2を下流側 Dとしたと きに弁体 3 3の上流側 Uに当接する弁座部 3 4と、 通気フィルタ 3 7を介し て弁体 3 3よりも上流側 Uの流路 3 5につながる通気孔 3 6と、 を備えてい る。 The second discharge member 30 according to the present invention has, as shown in, for example, FIG. 9 (cross-sectional view) and FIG. Part 31, a ring-shaped valve element 33 disposed inside the discharge part 31, and an opening end 31 d of the discharge part 31 1. The valve seat 34 that contacts the upstream side U of the valve body 33 when it is set to the side D, and the vent hole that connects to the flow path 35 on the upstream side U of the valve body 33 via the ventilation filter 37 3 and 6.
吐出部 3 1は、 通気孔 3 6に通気フィルタ 3 7を配置する必要上、 吐出孔 3 2を備える吐出部本体 3 1 aと、 その上流側 Uに配置されて薬液容器等の 口部に接続される連結部 3 1 bとの 2つの部材からなつている。 吐出部本体 3 1 aと連結部 3 1 bとは、 そのフランジ 3 1 f (接続部分 3 1 c ) に通気 フィルタ 3 7を挟んだ状態で、 超音波接着等の接合手段によって一体化され る。  Since the discharge section 31 needs to be provided with the ventilation filter 37 in the ventilation hole 36, the discharge section main body 31a provided with the discharge hole 32 and the discharge section 31 disposed at the upstream side U and at the mouth of a chemical solution container or the like. It is composed of two members, a connecting portion 31b to be connected. The discharge unit main body 3 1a and the connecting part 3 1b are integrated by a bonding means such as ultrasonic bonding with the ventilation filter 37 sandwiched between the flanges 31 f (connection part 31 c). .
図 9および図 1 0に示す吐出部材 3 0のうち、 吐出部本体 3 1 aと弁体 3 3との一体成形物は、 図 1 1にその平面図を示すように、 リング状の弁体 3 3を吐出部本体 3 1 aの内表面 3 1 eの少なくとも一部に密着させたもので ある。 なお、 図 1 1 (a) 中、 符号 3 6を付した点線で示される箇所は、 通気 フィルタ 3 7で覆われた通気孔を示している。  Among the discharge members 30 shown in FIGS. 9 and 10, the integrally molded product of the discharge portion main body 31 a and the valve body 33 is a ring-shaped valve body as shown in a plan view in FIG. 11. 33 is brought into close contact with at least a part of the inner surface 31e of the discharge portion main body 31a. In FIG. 11A, a portion indicated by a dotted line with reference numeral 36 indicates a ventilation hole covered with a ventilation filter 37.
図 1 1 (b) は吐出部本体 3 1 aと弁体 3 3との一体成形物を示す底面図で あって、 同図に示す吐出部本体 3 1 aでは、 その底部に、 当該底部を貫通す る孔 (射出孔) 3 1 gが設けられている。 吐出部本体 3 1 aは、 例えば吐出 部本体 3 1 a形成用の樹脂を金型内に射出することによって成形することが できるが、 その射出後に、 吐出部 3 1の開口端 3 1 d側 (図 1 0参照) の金 型 (可動金型) を取り替えて (あるいは移動して) 、 さらに吐出部本体 3 1 aの底部における射出孔 3 1 gから熱可塑性エラストマ一を射出すれば、 吐 出部本体 3 1 aと弁体 3 3とを一体成形によって製造することができる。 な お、 弁体 3 3を吐出部の開口端 3 1 d側から射出して一体成形する場合には 、 上記射出孔 3 1 gは不要である。  FIG. 11 (b) is a bottom view showing an integrally formed product of the discharge portion main body 31a and the valve body 33. In the discharge portion main body 31a shown in FIG. Holes (injection holes) 31 g are provided. The discharge unit main body 31 a can be molded by, for example, injecting a resin for forming the discharge unit main body 31 a into a mold. After the injection, the opening end 31 d side of the discharge unit 31 is formed. The mold (movable mold) (see FIG. 10) is replaced (or moved), and the thermoplastic elastomer is injected from the injection hole 31 g at the bottom of the discharge unit body 31 a. The protrusion main body 31a and the valve body 33 can be manufactured by integral molding. In the case where the valve element 33 is injected from the opening end 31 d side of the discharge part to be integrally molded, the injection hole 31 g is not necessary.
図 9および図 1 0に示す吐出部材 3 0のうち、 吐出部本体 3 1 a内に上流 側 Uから嵌着される弁座部 3 4は、 図 1 2にその平面図(a) と底面図(b) を 示すように、 フランジ 3 4 dを備える筒体 3 4 cと、 当該筒体 3 4 cのフラ ンジ 3 4 d側とは逆側の開口部を塞ぐようにして配置される弁座 3 4 aとを 備えている。 符号 3 4 bで示される部分は、 リング状の弁体 3 3の空洞部と ともに薬液等の流路 3 5を区画する部位である。 符号 3 4 eで示される部分 は、 筒体 3 4 cと弁座 3 4 aとの連結部である。 Of the discharge member 30 shown in FIG. 9 and FIG. 10, the valve seat portion 34 fitted into the discharge portion main body 31a from the upstream side U is shown in FIG. As shown in Fig. (B), a cylinder 34c having a flange 34d and a flange of the cylinder 34c are provided. And a valve seat 34a arranged so as to close the opening on the side opposite to the flange 34d side. The portion indicated by the reference numeral 34b is a portion that partitions the flow path 35 for the chemical solution or the like together with the hollow portion of the ring-shaped valve body 33. The portion indicated by the reference numeral 34 e is a connecting portion between the cylinder 34 c and the valve seat 34 a.
図 1 1 (a) に示す一体成形物において、 弁体 3 3はリング状である。 しか し、 弁体は吐出部本体 3 1 aの円周方向 Xに連続した (リング状の) ものに 限定されるものではなく、 例えば図 1 3 (a) に示すような形状であってもよ い。 なお、 弁体の形状が図 1 3 (a) に示すようなものである場合には、 弁体 3 3 ' の圧縮変形に伴って弁座 (図示せず) と吐出部本体 3 l a ' との間に 生じる流路 (図示せず) の領域が、 弁体 3 3がリング状である場合 (図 1 1 ) に比べて狭くなる。 従って、 弁体の形状は、 吐出部材に要求される流路の 領域の広狭に応じて適宜設定すればよい。 図 1 3 (a) 中、 符号 3 1 e 5 は吐 出部本体 3 1 aの内表面を示し、 符号 3 1 f ' は吐出部本体 3 1 aのフラン ジを示す。 In the integrally molded article shown in FIG. 11 (a), the valve body 33 has a ring shape. However, the valve body is not limited to the one that is continuous (ring-shaped) in the circumferential direction X of the discharge part main body 31a. For example, even if the shape is as shown in FIG. Good. When the shape of the valve body is as shown in Fig. 13 (a), the valve seat (not shown) and the discharge unit body 3 la 'are connected with the compression deformation of the valve body 33'. The area of the flow path (not shown) generated between them becomes narrower than when the valve element 33 is ring-shaped (FIG. 11). Therefore, the shape of the valve element may be appropriately set according to the width of the flow path region required for the discharge member. 1 in 3 (a), reference numeral 3 1 e 5 shows the inner surface of the ejection detecting portion main body 3 1 a, reference numeral 3 1 f 'denotes a flange of the discharge body 3 1 a.
図 1 3 (b) は、 図 1 3 (a) に示す 状の弁体 3 3 ' を備える吐出部材に用 いられる弁座部 3 4, を示す。 弁座部 3 4 ' の流路 3 5は、 図 1 3 (a) に示 す吐出部材の弁体 3 3 ' の形状に応じて設ければよい。 なお、 図 1 3 (b) 中 、 符号 3 4 a, は弁座を示す。  FIG. 13 (b) shows a valve seat 34 used for a discharge member provided with a valve element 33 ′ having the shape shown in FIG. 13 (a). The flow path 35 of the valve seat 3 4 ′ may be provided in accordance with the shape of the valve element 3 3 ′ of the discharge member shown in FIG. 13A. In FIG. 13 (b), reference numeral 34a denotes a valve seat.
第 2の吐出部材 3 0は、 例えば図 1 4に示すように、 容器本体 4 1の口部 に取り付けることによって用いられる。  The second discharge member 30 is used by being attached to the mouth of the container body 41, for example, as shown in FIG.
本発明に係る第 2の吐出部材およびそれを備える容器による吐出操作の一 連の工程を図 1 5および図 1 6に示す。 図 1 5 (a) は容器本体 4 1に圧を加 えていない状態を示している。 この状態では、 吐出部本体 3 1 a側の流路 3 5と連結部 3 1 b側の流路 3 5との間を弁体 3 3が閉鎖しており、 吐出孔 3 2と容器本体 4 1との連通が遮断されている。 それゆえ、 容器本体 4 1に収 容された内容液 4 4は吐出部 3 1から吐出されることなく、 容器本体 4 1お よび吐出部材 3 0内に留まる。 図 1 5 (b) は容器本体 4 1に圧を加えた状態 を示している。 この状態で弁体 3 3は、 流路 3 5を通じて上流側 Uから液圧 を受けており、 この液圧によって圧縮変形が生じている。 それゆえ、 弁体 3 3と弁座 3 4 aとの間に空隙が生じて (弁体 3 3が開放されて) 、 吐出部本 体 3 1 a側の流路 3 5と連結部 3 1 b側の流路 3 5との間が連通することと なる。 その結果、 容器本体 4 1に収容された内容液 4 4は液滴 4 5として吐 出部 3 1から吐出される。 FIG. 15 and FIG. 16 show a series of steps of the discharging operation using the second discharging member and the container having the same according to the present invention. FIG. 15A shows a state in which no pressure is applied to the container body 41. In this state, the valve element 33 is closed between the flow path 35 on the discharge section main body 3 1a side and the flow path 35 on the connection section 3 1b side, and the discharge hole 32 and the container body 4 are closed. Communication with 1 has been interrupted. Therefore, the content liquid 44 stored in the container body 41 is not discharged from the discharge part 31 and stays in the container body 41 and the discharge member 30. FIG. 15 (b) shows a state in which pressure is applied to the container body 41. In this state, the valve element 33 receives the hydraulic pressure from the upstream side U through the flow path 35, and the hydraulic pressure causes compression deformation. Therefore, valve element 3 There is a gap between the valve body 3 and the valve seat 3 4a (the valve body 33 is opened), and the flow path 35 on the discharge body 3 1a side and the flow path 3 on the connection part 3 1b side 3 Communication with 5 is established. As a result, the content liquid 44 stored in the container body 41 is discharged from the discharge unit 31 as a droplet 45.
図 1 6 (a) は、 図 1 5 (b) に示す状態の続きであって、 容器本体 4 1に対 する加圧を停止した状態を示している。 この状態で、 吐出部材の弁体 3 3に は内容液 4 3による液圧がかからなくなることから、 弁体 3 3が加圧前の形 状に復元して、 再び弁体 3 3と弁座 3 4 aとの間が閉鎖される。 図 1 6 (b) は、 図 1 6 (a) に示す状態の続きであって、 容器本体 4 1に対する加圧を停 止することで、 容器本体 4 1が加圧前の形状に復元しょうとしている状態を 示している。 この状態で吐出部材の弁体 3 3は流路 3 5を閉鎖していること から、 容器本体 4 1への外気の流入はもっぱら通気孔 3 6を介して実現され る。  FIG. 16 (a) is a continuation of the state shown in FIG. 15 (b), and shows a state in which pressurization of the container body 41 is stopped. In this state, since the liquid pressure due to the content liquid 43 is not applied to the valve element 33 of the discharge member, the valve element 33 is restored to the shape before pressurization, and the valve element 33 and the valve are again formed. The seat between the seats 3 4a is closed. Fig. 16 (b) is a continuation of the state shown in Fig. 16 (a). By stopping the pressurization of the container body 41, let the container body 41 restore its shape before pressurization. It shows the state that it is. In this state, the valve element 33 of the discharge member closes the flow path 35, so that the outside air flows into the container body 41 only through the ventilation hole 36.
図 1 4およぴ図 1 7に示すように、 内栓 4 3は、 容器 4 0の首部 4 2に揷 嵌されている。 図 1 4は、 容器 4 0の使用状態における断面を示すのに対し 、 図 1 7は、 容器 4 0の未開栓状態における断面図を示している。 図 1 7に 示す未開栓状態では、 吐出部材 3 0が容器本体 4 1に対して浅く揷嵌された 状態となっている。 この状態で、 内栓 4 3の先端部 4 3 aは、 吐出部 3 1の 内表面に設けられたフランジ 3 9に当接している。 その結果、 フランジ 3 9 と内栓 4 3の先端部 4 3 aとによって吐出部材 3 0の流路 3 4が分断される こととなり、 容器本体 2 1内に収容される内容液の無菌状態をより高度に維 持したり、 内容液の劣化 (空気酸化等) の進行を防止したりすることができ る。  As shown in FIGS. 14 and 17, the inner plug 43 is fitted into the neck 42 of the container 40. FIG. 14 shows a cross section of the container 40 in a use state, while FIG. 17 shows a cross section of the container 40 in an unopened state. In the unopened state shown in FIG. 17, the discharge member 30 is in a state where it is shallowly fitted to the container body 41. In this state, the distal end 43 a of the inner plug 43 is in contact with the flange 39 provided on the inner surface of the discharge portion 31. As a result, the flow path 34 of the discharge member 30 is divided by the flange 39 and the distal end 43 a of the inner plug 43, and the aseptic state of the liquid contained in the container body 21 is reduced. It can be maintained at a higher level and can prevent the deterioration of the content liquid (air oxidation, etc.).
図 1 7に示す吐出部材 3 0には、 その吐出部本体 3 1 aのネジ部 3 1 hに キャップ 4 6が螺設されており、 さらにこのキャップ 4 6の内表面には、 吐 出部材 3 1の吐出孔 3 2と接する部位にスポンジ 4 7が配置されている。 こ のスポンジ 4 7は、 吐出操作の終了後に吐出孔 3 2に残存する残留液 3 5 ' In the discharge member 30 shown in FIG. 17, a cap 46 is screwed on the screw portion 31 h of the discharge portion main body 31a, and further, on the inner surface of the cap 46, a discharge member is provided. A sponge 47 is arranged at a position in contact with the discharge hole 32 of 31. The sponge 47 holds the residual liquid 3 5 ′ remaining in the discharge hole 32 after the end of the discharge operation.
(図 1 6 (b) 参照) を吸い取ることから、 再度の滴下操作の際に当該残留液 を吐出しないようにすることができる。 なお、 符号 4 6 aは、 キャップ 4 6 の内表面に設けられたネジ部を示す。 (See Fig. 16 (b)), so that it is possible to prevent the residual liquid from being discharged at the time of another dropping operation. Reference numeral 46 a is a cap 46 2 shows a threaded portion provided on the inner surface of a.
図 1 7に示す吐出部材 3 0において、 キャップの開口端 4 6 bは吐出部材 3 0の通気孔 3 6を塞いでいる。 この結果、 容器本体 4 1内に収容された薬 液の溶媒 (水) 等が通気フィルタ 3 7から徐々に蒸散して、 収容液の p Hが 変動してしまう、 といった問題が生じるのを防止することができる。  In the discharge member 30 shown in FIG. 17, the opening end 46 b of the cap closes the ventilation hole 36 of the discharge member 30. As a result, it is possible to prevent the problem that the solvent (water) of the chemical solution contained in the container body 41 gradually evaporates from the ventilation filter 37 and the pH of the contained solution fluctuates. can do.
第 2の吐出部材は前述のものに限定されるものではなく、 例えば図 1 8に 示すような形状のものであってもよい。  The second ejection member is not limited to the one described above, and may have a shape as shown in FIG. 18 for example.
図 1 8に示す吐出部材 3 0 ' は、 図 9に示す吐出部材 3 0の場合と同様に 、 底部に吐出孔 3 2を備える有底略筒状の吐出部 3 1と、 吐出部 3 1の内部 に配置されてなる、 Vング状の弁体 3 3 ' と、 吐出部 3 1の開口端側から冠 着されて、 吐出孔 3 2を下流側 Dとしたときに弁体 3 3 ' の上流側 Uに当接 する弁座部 3 4と、 通気フィルタ 3 7を介して流路 3 5と連通する通気孔 3 6と、 を備えており、 さらに弁座部 3 4よりも上流側 Uに配置されて流路 3 5を覆う通液フィルタ 3 8を備えている。 この吐出部材 3 0は、 弁体 3 1の 形状およびそれを収容する吐出部 3 1の吐出孔 3 2付近での形状が異なるこ とと、 流路 3 5中に通液フィルタ 3 8を備えていることのほかは、 図 9等に 示す吐出部材 1 0と同様である。  As in the case of the discharge member 30 shown in FIG. 9, the discharge member 30 ′ shown in FIG. 18 has a substantially cylindrical bottomed discharge part 31 having a discharge hole 32 at the bottom, and a discharge part 31. And a V-shaped valve element 3 3 ′, which is disposed inside of the valve element 3, when the discharge port 3 2 is mounted on the downstream end side of the discharge port 3 1 when the discharge port 3 2 is set to the downstream side D. And a vent hole 36 communicating with the flow path 35 via a ventilation filter 37, and further upstream from the valve seat portion 34. There is provided a liquid passage filter 38 arranged in the U and covering the flow path 35. The discharge member 30 has a shape different from the shape of the valve body 31 and a shape in the vicinity of the discharge hole 32 of the discharge part 31 for accommodating the valve body 31, and includes a liquid passage filter 38 in the flow path 35. Except for this, it is the same as the discharge member 10 shown in FIG. 9 and the like.
〔第 3の吐出部材ぉよび容器〕  [Third discharge member and container]
本発明に係る第 3の吐出部材 5 0は、 例えば図 1 9 (断面図) および図 2 0 (分解断面図) に示すように、 底部に吐出孔 5 2を備える有底略筒状の吐 出部 5 1と、 吐出部 5 1内 (吐出孔 5 2につながる流路 5 5 ) に配置されて 、 上流側 Uから液圧を受けていない状態で吐出孔 5 2を閉鎖しかつ上流側 U から液圧を受けると伸張変形して吐出孔 5 2を開放する弾性体の弁体 5 3と 、 通気フィルタ 5 7を介して弁体 5 3よりも上流側 Uの流路 5 5につながる 通気孔 5 6と、 を備えている。  The third discharge member 50 according to the present invention has, as shown in FIG. 19 (cross-sectional view) and FIG. 20 (exploded cross-sectional view), a bottomed substantially cylindrical discharge member having a discharge hole 52 at the bottom. The discharge port 51 is disposed in the discharge section 51 and the discharge section 51 (the flow path 55 connected to the discharge port 52), and closes the discharge port 52 without receiving the hydraulic pressure from the upstream side U and closes the upstream side. The elastic valve element 53 that expands and deforms when receiving the hydraulic pressure from U to open the discharge hole 52, and is connected to the flow path 55 upstream of the valve element 53 via the ventilation filter 57 via the ventilation filter 57. Vent holes 5 and 6 are provided.
吐出部 5 1は、 通気孔 5 6に通気フィルタ 5 7を配置する必要上、 吐出孔 5 2を備える吐出部本体 5 1 aと、 その上流側 Uに配置されて薬液容器等の 口部に接続される連結部 5 1 bとの 2つの部材からなつている。 吐出部本体 5 1 aと連結部 5 1 bとは、 そのフランジ 5 1 f (接続部分 5 1 c ) に通気 フィルタ 5 7を挟んだ状態で、 超音波接着等の接合手段によって一体化され る。 Since the discharge section 51 needs to be provided with a ventilation filter 57 in the ventilation hole 56, the discharge section main body 51a having the discharge hole 52 and the upstream section U are provided at the mouth of a chemical solution container or the like. It is composed of two members, a connecting portion 5 1 b to be connected. The discharge part body 51a and the connecting part 51b are ventilated to the flange 51f (connection part 51c). With the filter 57 sandwiched therebetween, they are integrated by joining means such as ultrasonic bonding.
図 2 1は、 吐出部本体 5 l aの平面図 (上流側 Uから見た図) である。 こ の図に示すように、 略筒状である吐出部本体 5 1 aの底部には、 弁本体部 5 3 aの突起と繋合させるための凸条 (弁座) 5 2 bが設けられている。 また 、 吐出部本体 5 1 aと対になる連結部 5 1 bを取り付けるためのフランジ 5 1 f (接続部分 5 1 c ) 部分には、 所定の間隔で通気孔 5 6が設けられてお り、 当該通気孔 5 6には無菌的な空気の流入を実現するための通気フィルタ 5 7が配置されている。  FIG. 21 is a plan view (viewed from the upstream side U) of the discharge unit main body 5la. As shown in this figure, a convex portion (valve seat) 52 b for connecting with a projection of the valve body 53 a is provided at the bottom of the substantially cylindrical discharge portion body 51 a. ing. In addition, ventilation holes 56 are provided at predetermined intervals in the flange 51 f (connection portion 51 c) for attaching the connecting portion 51 b that is paired with the discharge portion main body 51 a. The ventilation hole 56 is provided with a ventilation filter 57 for realizing aseptic air inflow.
図 2 2は、 弁体 5 3と、 これを繋止する弁体支持部材 5 4との結合体を示 しており、 同図(a) はその平面図 (上流側 Uから見た図) であって、 同図(b ) はその底面図 (下流側 Dから見た図) である。 この図に示すように、 弁体 5 3を吐出部本体 5 1 a内に配置するための弁体支持部材 5 4は、 筒体 5 4 aと、 その底部にあって弁体 5 3との繋合を実現する繋止部 5 4 bと、 これ と逆側の開口端にあって吐出部本体 5 1 aと嵌合させるためのフランジ部 5 4 cとを備えている。  FIG. 22 shows a combined body of the valve body 53 and the valve body supporting member 54 for connecting the valve body 53, and FIG. 22A is a plan view thereof (a view from the upstream side U). Figure (b) is a bottom view (view from downstream D). As shown in this figure, a valve element supporting member 54 for disposing the valve element 53 in the discharge part main body 51a is formed by a cylinder 54a and a valve element 53 at the bottom thereof. It has a locking portion 54b for realizing the connection, and a flange portion 54c at the opening end on the opposite side to fit with the discharge portion main body 51a.
図 1 9〜図 2 2に示すように、 弁体 5 3は、 弁体支持部材 5 4に繋止させ た上で、 吐出部本体 5 1 aの内表面 5 1 eに嵌着される。  As shown in FIGS. 19 to 22, the valve body 53 is fitted to the inner surface 51 e of the discharge portion main body 51 a after being fixed to the valve body support member 54.
弁体 5 3が熱可塑性を有する弾性体材料 (熱可塑性エラストマ一など) を 用いて形成されたものである場合には、 弁体 5 3と弁体支持部材 5 4とをィ ンサート成形や多色成形によつて一体成形することができる。 これにより、 両部材の製造を簡易に行うことができる。 弁体 5 3を形成する弾性体材料が 熱可塑性を有しないために、 射出成形等の成形技術を使用し得ないものであ る場合には、 例えば注型用の型に弁体支持部材 5 4をィンサートしてから弁 体 5 3を注型成形することにより、 弁体と弁体支持部材 5 4とを一体的に成 形することができる。  When the valve body 53 is formed using an elastic material having thermoplasticity (such as thermoplastic elastomer), the valve body 53 and the valve body support member 54 may be formed by insert molding or multiple molding. It can be integrally molded by color molding. Thereby, both members can be easily manufactured. In the case where the molding material such as injection molding cannot be used because the elastic material forming the valve body 53 does not have thermoplasticity, for example, the valve body supporting member 5 is attached to a casting mold. By inserting the valve body 53 into the mold after insert 4, the valve body and the valve body support member 54 can be integrally formed.
図 1 9に示す実施形態において、 弁体 5 3は、 弁軸としての弁本体部 5 3 aと、 弁本体部 5 3 aの先端にあって弁頭をなす突起 5 3 bと、 弁本体部 5 3 aを弁体支持部材と繋合させるためのフランジ部 5 3 cとからなっている 図 1 9および図 2 0に示す弾性部材は、 例えば図 2 3に示すように、 吐出 部本体 5 1 aの開口端 (図 2 0の符号 5 1 d参照) 側から、 弁体 5 3を備え る弁体支持部材 5 4を揷入し、 弁本体部 5 3 aの突起 5 3 bを吐出部 5 2の 流路内壁 5 2 aに設けられた凸条 5 2 bに配置した後、 上流側 Uから強い液 圧や空気圧を負荷して、 弁本体の突起 5 3 bを吐出孔 5 2側へ摺動させるこ とによって得られる。 In the embodiment shown in FIG. 19, the valve element 53 includes a valve body 53 a as a valve shaft, a projection 53 b at the tip of the valve body 53 a that forms a valve head, and a valve body 53. And a flange 53c for connecting the portion 53a to the valve body support member. As shown in FIG. 23, for example, the elastic member shown in FIGS. 19 and 20 is configured such that the valve body 53 is connected to the opening end (see reference numeral 51 d in FIG. 20) of the discharge portion main body 51 a. After inserting the valve body support member 54 provided, and arranging the projection 53b of the valve body 53a on the convex ridge 52b provided on the flow path inner wall 52a of the discharge part 52, It can be obtained by applying a strong hydraulic pressure or air pressure from the upstream side U and sliding the projection 53 b of the valve body toward the discharge hole 52.
上記第 1の吐出部材 5 0は、 例えば図 2 4に示すように、 容器本体 6 1の 口部に取り付けることによって用いられる。 なお、 図 2 4に示す容器 6 0に おいて、 容器本体 6 1の首部 6 2には内栓 6 3が設けられている。  The first discharge member 50 is used by being attached to the mouth of a container body 61 as shown in FIG. 24, for example. In the container 60 shown in FIG. 24, an inner stopper 63 is provided at the neck 62 of the container body 61.
本発明の吐出部材およびそれを備える容器を用!/、た吐出操作の一連の工程 を図 2 5および図 2 6に示す。 図 2 5 (a) は容器本体 6 1に圧を加えていな い状態を示している。 この状態では、 吐出孔 5 2における流路 5 5と、 弁体 5 3よりも上流側にある流路 5 5との間が弁体 5 3によって閉鎖されており 、 吐出孔 5 2と容器本体 6 1との連通が遮断されている。 それゆえ、 容器本 体 6 1に収容された内容液 6 4は吐出部 5 1から吐出されることなく、 容器 本体 6 1および吐出部材 5 0内に留まる。 図 2 5 (b) は容器本体 6 1に圧を 加えた状態を示している。 この状態で弁体 5 3は、 流路 5 5を通じて上流側 Uから液圧を受けており、 この液圧によって吐出孔 5 2側への伸張変形が生 じている。 それゆえ、 弁本体部 5 3 aの突起 5 3 bと、 吐出部 5 2の流路内 壁 5 2 aに設けられた ώ条 5 2 bとの間が連通することとなって、 容器本体 6 1に収容された内容液 6 4は液滴 6 5として吐出部 5 1から吐出される。 図 2 6 (a) は、 図 2 5 (b) に示す状態の続きであって、 容器本体 6 1に対 する加圧を停止した状態を示している。 この状態で、 吐出部材の弁体 5 3に は内容液 6 4による液圧がかからなくなることから、 加圧前の形状に復元し て、 再び弁体 5 3と凸条 5 2 bとの間が閉鎖される。 図 2 6 (b) は、 図 2 6 (a) に示す状態の続きであって、 容器本体 6 1が加圧前の形状に復元しょう としている状態を示している。 この状態で吐出部材の弁体 5 3は、 吐出部の 凸条 5 2 b部分において流路 5 5を閉鎖していることから、 容器本体 6 1 へ JP2003/009572 For use with the discharge member of the present invention and a container having the same! Fig. 25 and Fig. 26 show a series of steps of the discharge operation. FIG. 25 (a) shows a state in which no pressure is applied to the container body 61. In this state, the space between the flow path 55 in the discharge hole 52 and the flow path 55 upstream of the valve 53 is closed by the valve 53, and the discharge hole 52 and the container body are closed. 6 Communication with 1 is blocked. Therefore, the content liquid 64 stored in the container body 61 is not discharged from the discharge part 51 and stays in the container body 61 and the discharge member 50. FIG. 25 (b) shows a state in which pressure is applied to the container body 61. In this state, the valve 53 receives the hydraulic pressure from the upstream side U through the flow path 55, and the hydraulic pressure causes the expansion deformation toward the discharge hole 52 side. Therefore, the projection 5 3 b of the valve body 53 a communicates with the a 52 b provided on the inner wall 52 a of the discharge part 52, and the container body The content liquid 64 stored in 61 is discharged from the discharge unit 51 as droplets 65. FIG. 26 (a) is a continuation of the state shown in FIG. 25 (b), and shows a state in which pressurization of the container body 61 is stopped. In this state, since the liquid pressure due to the content liquid 64 is not applied to the valve element 53 of the discharge member, the valve element 53 is restored to the shape before pressurization, and the valve element 53 and the ridge 52 b are again formed. The space is closed. FIG. 26 (b) is a continuation of the state shown in FIG. 26 (a), and shows a state in which the container body 61 is trying to restore the shape before pressurization. In this state, the valve member 53 of the discharge member closes the flow path 55 at the convex portion 52 b of the discharge portion, and thus moves to the container body 61. JP2003 / 009572
23 の外気の流入はもっぱら通気孔 5 6を介して実現される。  The inflow of outside air at 23 is realized exclusively through vents 56.
図 2 4および図 2 7に示すように、 内栓 6 3は、 容器 6 0の首部 6 2に挿 嵌されている。 この内栓 6 3の作用については、 上記第 2の吐出部材 3 0を 備える容器 4 0の場合と同様である。 なお、 図 2 4は、 容器 6 0の使用状態 における断面を示すのに対し、 図 2 7は、 容器 6 0の未開栓状態における断 面図を示している。 図 2 7中、 符号 6 3 aは内栓 6 3の先端部を示し、 符号 5 9は、 吐出部 5 1の内表面に設けられたフランジを示す。  As shown in FIGS. 24 and 27, the inner plug 63 is inserted into the neck 62 of the container 60. The function of the inner plug 63 is the same as that of the container 40 including the second discharge member 30 described above. FIG. 24 shows a cross section of the container 60 in the used state, while FIG. 27 shows a cross-sectional view of the container 60 in an unopened state. In FIG. 27, reference numeral 63 a indicates a distal end portion of the inner plug 63, and reference numeral 59 indicates a flange provided on the inner surface of the discharge portion 51.
図 2 7に示す吐出部材 5 1には、 さらに、 その吐出部本体 5 1 aのネジ部 分 5 1 hにキャップ 6 6が螺設されており、 さらにこのキャップ 6 6の内表 面には、 吐出部材 5 1の吐出孔 5 2と接する部位にスポンジ 6 7が配置され ている。 また、 キャップの開口端 6 6 bは通気孔 5 6を塞いでいる。 このス ポンジ 6 7やキャップの開口端 6 6 bの作用については、 上記第 2の吐出部 材 3 0を備える容器 4 0の場合と同様である。 なお、 図 2 7中、 符号 6 6 a は、 キャップ 6 6の内表面に設けられたネジ部を示す。  In the discharge member 51 shown in FIG. 27, a cap 66 is further screwed on the screw portion 51 h of the discharge portion main body 51a, and further, on the inner surface of the cap 66, A sponge 67 is disposed at a position in contact with the discharge hole 52 of the discharge member 51. The open end 66 b of the cap closes the ventilation hole 56. The functions of the sponge 67 and the opening end 66 b of the cap are the same as those in the case of the container 40 including the second discharge member 30. In FIG. 27, reference numeral 66 a denotes a screw portion provided on the inner surface of the cap 66.
〔第 4の吐出部材ぉよび容器〕  [Fourth discharging member and container]
本発明に係る第 4の吐出部材 7 0は、 例えば図 2 8に示すように、 底部に 吐出孔 7 2を備える有底略筒状の吐出部 7 1と、 吐出部 7 1の外表面側から 弁座 7 4に当接して、 上流側 Uから液圧を受けていない状態で吐出孔 7 2を 閉鎖しかつ上流側 Uから液圧を受けると伸張変形して吐出孔 7 2を開放する 弾性体の弁体 7 3と、 通気フィルタ 7 7を介して弁体 7 3よりも上流側の流 路につながる通気孔 7 6と、 を備えている。  For example, as shown in FIG. 28, the fourth discharge member 70 according to the present invention includes a bottomed substantially cylindrical discharge portion 71 having a discharge hole 72 at the bottom, and an outer surface side of the discharge portion 71. From the valve seat 74, closes the discharge hole 72 when not receiving the hydraulic pressure from the upstream side U, and expands and deforms when receiving the hydraulic pressure from the upstream side U to open the discharge hole 72. An elastic valve element 73 and a ventilation hole 76 connected to a flow path upstream of the valve element 73 via a ventilation filter 77 are provided.
吐出部 7 1は、 通気孔 7 6に通気フィルタ 7 7を配置する必要上、 上記第 1の吐出部材の場合と同様に、 吐出孔 7 2を備える吐出部本体 7 1 aと、 そ の上流側 Uに配置されて薬液容器等の口部に接続される連結部 7 1 bとの 2 つの部材からなつている。 吐出部本体 7 1 aと連結部 7 1 bとは、 そのフラ ンジ 7 1 f (接続部分 7 1 c ) に通気フィルタ 7 7を挟んだ状態で、 超音波 接着等の接合手段によつて一体化される。  Since the discharge section 71 needs to be provided with the ventilation filter 77 in the ventilation hole 76, similarly to the case of the first discharge member, the discharge section main body 71 a having the discharge hole 72 and the upstream thereof It is composed of two members, a connecting portion 71b which is arranged on the side U and connected to the mouth of the drug solution container or the like. The discharge unit main body 71a and the connecting part 71b are integrated by a bonding means such as ultrasonic bonding with the ventilation filter 77 sandwiched between the flange 71f (connection part 71c). Be transformed into
図 2 9 (a) は、 吐出部本体 7 l aの底面図 (下流側 Dから見た図) であつ て、 同図(b) は図 2 8の A— A断面図である。 吐出部本体 7 l aには、 これ と対になる連結部 7 1 bを取り付けるためのフランジ 7 1 f (接続部分 7 1 c ) 部分において、 図 2 1に示す場合と同様の、 複数の通気孔 7 6およびこ の通気孔を塞ぐ通気フィルタ 7 7が設けられている。 通気孔 7 6および通気 フィルタ 7 7の作用については、 上記第 3の吐出部材 5 0を備える容器 6 0 の場合と同様である。 FIG. 29 (a) is a bottom view of the discharge unit main body 7la (a view as viewed from the downstream side D), and FIG. 29 (b) is a sectional view taken along line AA of FIG. The discharge section body 7 la has this At the flange 71 f (connection part 71 c) for attaching the connecting part 71 b that is to be paired with the same, close the multiple ventilation holes 76 and these ventilation holes as shown in Fig. 21 A ventilation filter 77 is provided. The functions of the vent hole 76 and the vent filter 77 are the same as in the case of the container 60 including the third discharge member 50 described above.
図 2 8〜図 2 9に示すように、 弁体 7 3は、 有底略筒状の部材である吐出 部本体 7 1 aの底部外表面と、 当該吐出部本体 7 1 aの底部にあって流路 7 5を区画しかつ吐出部を閉鎖するための弁座 7 4における底面 (外表面) と 、 の双方に接した状態で配置される。 この弁体 7 3は、 例えば熱可塑性を有 する弾性体材料を用いて、 樹脂製の吐出部本体 7 1 aにおける外表面側に、 当該吐出部本体 7 1 aと一体成形するのが好ましい。 一体成形によって、 吐 出部材 7 0の製造を簡易なものとすることができる。  As shown in FIGS. 28 to 29, the valve element 73 is provided on the outer surface of the bottom of the discharge unit body 71a, which is a substantially cylindrical member with a bottom, and on the bottom of the discharge unit body 71a. The flow path 75 is partitioned so as to be in contact with both the bottom surface (outer surface) of the valve seat 74 for closing the discharge portion. The valve body 73 is preferably formed integrally with the discharge section body 71a on the outer surface side of the resin discharge section body 71a using, for example, an elastic material having thermoplasticity. By integral molding, the production of the discharge member 70 can be simplified.
上記第 4の吐出部材 7 0は、 例えば図 3 0 (a) に示すように、 容器本体 8 1の口部に取り付けることによって用いられる。 なお、 図 3 0 (a) に示す容 器 8 0において、 容器本体 8 1の首部 8 2には内栓 8 3が設けられている。 この内栓 8 3の作用については、 上記第 2の吐出部材 3 0を備える容器 4 0 や上記第 3の吐出部材 5 0を備える容器 6 0の場合と同様である。  The fourth discharge member 70 is used by being attached to the mouth of the container body 81, for example, as shown in FIG. In the container 80 shown in FIG. 30 (a), an inner stopper 83 is provided on a neck portion 82 of the container body 81. The function of the inner plug 83 is the same as that of the container 40 having the second discharge member 30 and the container 60 having the third discharge member 50.
本発明の吐出部材およびそれを備える容器を用いた吐出操作の一連の工程 を図 3 0および図 3 1に示す。 図 3 0 (a) は容器本体 8 1に圧を加えていな い状態を示している。 この状態では、 吐出孔 7 2における流路 7 5が弁体 7 3によって閉鎖されており、 吐出孔 7 2の外部と容器本体 8 1との連通が遮 断されている。 それゆえ、 容器本体 8 1に収容された内容液 8 4は吐出部 7 1から吐出されることなく、 容器本体 8 1および吐出部材 7 0内に留まる。 図 3 0 (b) は容器本体 8 1に圧を加えた状態を示している。 この状態で弁体 7 3は、 流路 7 5を通じて上流側 Uから液圧を受けており、 この液圧によつ て吐出孔 7 2側への伸張変形が生じている。 それゆえ、 弁体 7 3と弁座部 7 4との間に流路が形成されることとなって、 容器本体 8 1に収容された内容 液 8 4は液滴 8 5として吐出部 7 1から吐出される。  FIG. 30 and FIG. 31 show a series of steps of a discharging operation using the discharging member of the present invention and a container provided with the discharging member. FIG. 30 (a) shows a state in which no pressure is applied to the container body 81. In this state, the flow path 75 in the discharge hole 72 is closed by the valve body 73, and the communication between the outside of the discharge hole 72 and the container body 81 is blocked. Therefore, the content liquid 84 stored in the container body 81 remains in the container body 81 and the discharge member 70 without being discharged from the discharge part 71. FIG. 30 (b) shows a state where pressure is applied to the container body 81. In this state, the valve body 73 receives the hydraulic pressure from the upstream side U through the flow path 75, and the hydraulic pressure causes the expansion deformation toward the discharge hole 72 side. Therefore, a flow path is formed between the valve body 73 and the valve seat portion 74, and the content liquid 84 accommodated in the container body 81 becomes a droplet 85 as the discharge portion 71. Is discharged from.
図 3 1 (a) は、 図 3 0 (b) に示す状態の続きであって、 容器本体 8 1に対 する加圧を停止した状態を示している。 この状態で、 吐出部材の弁体 7 3に は内容液 8 4による液圧がかからなくなることから、 加圧前の形状に復元し て、 再び弁体 7 3と弁座 7 4との間が閉鎖される。 図 3 1 (b) は、 図 3 1 (a ) に示す状態の続きであって、 容器本体 8 1が加圧前の形状に復元しようと している状態を示している。 この状態で吐出部材の弁体 7 3は、 吐出部 7 1 aの弁座 7 4との間において流路 7 5を閉鎖していることから、 容器本体 8 1への外気の流入はもつばら通気孔 7 6を介して実現される。 FIG. 31 (a) is a continuation of the state shown in FIG. This shows a state in which the pressurization is stopped. In this state, since the liquid pressure due to the content liquid 84 is not applied to the valve element 73 of the discharge member, the shape is restored to the state before pressurization, and the valve element 73 and the valve seat 74 are returned again. Is closed. FIG. 31 (b) is a continuation of the state shown in FIG. 31 (a), and shows a state where the container body 81 is trying to restore the shape before pressurization. In this state, since the valve body 73 of the discharge member closes the flow path 75 between the valve seat 74 of the discharge portion 71a and the outside air flowing into the container body 81, the valve body 73 has a rounded shape. This is realized through the ventilation holes 76.
図 3 2に示す吐出部材 7 0 ' は、 第 4の吐出部材の他の実施形態である。 弁体の材質に熱可塑性を有する弾性体材料を使用した場合には、 図 2 8に示 す吐出部材 7 0のように、 弁体 7 3と吐出部本体 7 1 aとを一体成形するこ とができる。 一方、 弁体 7 3は十分に柔軟で、 液圧によって容易に撓曲変形 をなすものであれば、 熱可塑性エラストマ一以外の弾性体、 すなわち熱可塑 性を有しないゴム等からなるものであってもよい。 弁体を形成する弾性体材 料が熱可塑性を有しないために、 射出成形等によって成形し得ないものであ る場合には、 例えば図 3 2に示す実施形態のように、 弁体 7 3 ' を吐出部本 体 7 l a ' と弁座 7 4 (および筒体 7 4 a ) との間に挟持させることによつ て、 吐出部 7 1内に配置すればよい。  A discharge member 70 ′ shown in FIG. 32 is another embodiment of the fourth discharge member. When an elastic material having thermoplasticity is used as the material of the valve body, the valve body 73 and the discharge portion main body 71a are integrally formed as shown in a discharge member 70 shown in FIG. Can be. On the other hand, the valve body 73 is made of an elastic body other than the thermoplastic elastomer, that is, a rubber having no thermoplasticity, as long as it is sufficiently flexible and easily bends and deforms by hydraulic pressure. You may. When the elastic material forming the valve body cannot be molded by injection molding or the like because it does not have thermoplasticity, for example, as shown in the embodiment shown in FIG. May be disposed in the discharge portion 71 by being sandwiched between the discharge portion main body 7 la 'and the valve seat 74 (and the cylindrical body 74 a).
図 3 2に示す吐出部材 7 0, は、 吐出部本体 7 1 a, と弁体 7 3 ' が異な るほかは、 図 2 8に示す吐出部材 7 0と同様である。  The discharge member 70 shown in FIG. 32 is the same as the discharge member 70 shown in FIG. 28 except that the discharge part main body 71 a and the valve element 73 ′ are different.
〔第 5の吐出部材ぉよび容器〕  [Fifth discharging member and container]
本発明に係る第 5の吐出部材 9 0は、 例えば図 3 3に示すように、 底部に 孔 9 1 dを備える有底略筒状の吐出部 9 1と、 略環状の弁本体部 9 3 bとこ れに連設する略環状の薄肉部 9 3 aとを有し、 薄肉部 9 3 aを孔 9 1 dから 吐出部 9 1の外部に露出した状態で弁本体部 9 3 bを吐出部 9 1の内部に固 定してなる弁体 9 3と、 吐出部 9 1の内部に配置されて弁体 9 3とともに吐 出孔 9 2を区画してなる円柱状の弁体支持部 9 4 aと、 通気フィルタ 9 7を 介して弁体 9 3よりも上流側 Uの流路 9 5につながる通気孔 9 6と、 を備え ている。  The fifth discharge member 90 according to the present invention includes, as shown in FIG. 33, for example, a substantially cylindrical bottomed discharge portion 91 having a hole 91 d at the bottom, and a substantially annular valve body portion 93. b and a substantially annular thin portion 93a connected thereto, and discharges the valve body 93b with the thin portion 93a exposed through the hole 91d to the outside of the discharge portion 91. A valve body 93 fixed inside the portion 91, and a cylindrical valve body support portion 9 disposed inside the discharge portion 91 and defining the discharge hole 92 together with the valve body 93. 4a, and a ventilation hole 96 connected to a flow path 95 upstream of the valve element 93 via a ventilation filter 97.
吐出孔 9 2は、 通常、 弁体 9 3の薄肉部 9 3 aによって閉鎖されているが 9572 The discharge hole 92 is normally closed by a thin portion 93a of the valve body 93. 9572
26  26
、 流路 9 5を通じて上流側から弁体 9 3に液圧がかかると、 薄肉部 9 3 aに 伸張変形が生じて、 薄肉部 9 3 aと弁体支持部 9 4 aとの間に空隙が生じる 。 これにより、 当該空隙を通じて内容液を吐出することができる。 When hydraulic pressure is applied to the valve body 93 from the upstream side through the flow passage 95, the thin portion 93a is elongated and deformed, and a gap is formed between the thin portion 93a and the valve body support portion 94a. Occurs. Thereby, the content liquid can be discharged through the gap.
図 3 3に示す実施形態において、 弁体 9 3は、 その薄肉部 9 3 aを吐出部 9 1 (吐出部本体 9 l a ) の孔 9 1 dに露出させた状態で、 吐出部本体 9 1 aの内表面に固定されている。 図 3 3中、 符号 9 4 cは、 弁体支持部 9 4 a とフランジ部 9 4 bとを保持して、 弁体支持部材 9 4を吐出部 9 1 (吐出部 本体 9 l a ) 内に固定する筒部を示す。 弁本体部 9 3 bは、 吐出部本体 9 1 aの内表面と一体化するのに十分な厚みを有していればよい。  In the embodiment shown in FIG. 33, the valve body 93 has a thin portion 93 a exposed to a hole 91 d of the discharge portion 91 (discharge portion main body 9 la), and the discharge portion main body 91 It is fixed to the inner surface of a. In FIG. 33, reference numeral 94 c denotes a valve body supporting member 94 that holds the valve body supporting portion 94 a and the flange portion 94 b and moves the valve body supporting member 94 into the discharging portion 91 (the discharging portion body 9 la). 3 shows a tubular portion to be fixed. It is sufficient that the valve body 93 b has a sufficient thickness to be integrated with the inner surface of the discharge body 91 a.
吐出部 9 1は、 通気孔 9 6に通気フィルタ 9 7を配置する必要上、 吐出孔 9 2を備える吐出部本体 9 1 aと、 その上流側 Uに配置されて薬液容器等の 口部に接続される連結部 9 1 bとの 2つの部材からなつている。 吐出部本体 9 1 aと連結部 9 1 bとは、 接続部分 9 1 cに通気フィルタ 9 7を挟んだ状 態で、 超音波接着等の接合手段によって一体化される。  Since the discharge section 91 needs to be provided with the ventilation filter 97 in the ventilation hole 96, the discharge section main body 91a having the discharge hole 92 and the upstream section U and the opening of the chemical solution container are provided. It is composed of two members, a connecting part 9 1b to be connected. The discharge unit main body 91a and the connecting part 91b are integrated by a joining means such as ultrasonic bonding with the ventilation filter 97 sandwiched between the connecting parts 91c.
第 5の吐出部材 9 0は、 例えば図 3 4に示すように、 容器本体 1 0 1の口 部に取り付けることによって用いられる。  The fifth discharge member 90 is used by being attached to the mouth of the container body 101, for example, as shown in FIG.
本発明に係る第 5の吐出部材 9 0およびそれを備える容器 1 0 0による吐 出操作の一連の工程を図 3 6および図 3 7に示す。 図 3 6 (a) は容器本体 1 0 1に圧を加えていない状態を示しており、 この状態で、 吐出部材の弁体 9 3は吐出孔 9 2を閉鎖している。 それゆえ、 容器本体 1 0 1に収容された内 容液 1 0 4は吐出部 9 1から吐出されることなく、 容器本体 1 0 1および吐 出部材内に留まる。 図 3 6 (b) は容器本体 1 0 1に圧を加えた状態を示して いる。 この状態では、 吐出部材の弁体 9 3に上流側 Uから内容液 1 0 4によ る液圧がかかっており、 これによつて弁体 9 5が伸張変形することから、 吐 出孔 9 2が開放されて、 内容液 1 0 4が液滴 1 0 5として吐出される。 なお 、 図 3 8は、 図 3 6 (b) に示す吐出部 9 1の状態を拡大して示すものである 図 3 7 (a) は、 図 3 6 (b) に示す状態の続きであって、 容器本体 1 0 1に 対する加圧を停止した状態を示している。 この状態で、 吐出部材の弁体 9 3 には内容液 1 0 4による液圧がかからなくなることから、 弁体 9 3が加圧前 の形状に復元して、 再び吐出孔 9 2が閉鎖される。 さらに、 図 3 7 (b) は、 図 3 7 (a) に示す状態の続きであって、 容器本体 1 0 1に対する加圧を停止 することで、 容器本体 1 0 1が加圧前の形状に復元しょうとしている状態を 示している。 この状態で吐出部材の弁体 9 3は吐出孔 9 2を閉鎖しているこ とから、 容器本体 1 0 1への外気の流入は、 もっぱら通気孔 9 6を介して実 現さ 3^る。 FIGS. 36 and 37 show a series of steps of a discharging operation using the fifth discharging member 90 and the container 100 including the same according to the present invention. FIG. 36 (a) shows a state in which no pressure is applied to the container body 101, and in this state, the valve member 93 of the discharge member closes the discharge hole 92. Therefore, the liquid solution 104 accommodated in the container body 101 is not discharged from the discharge part 91 and stays in the container body 101 and the discharge member. FIG. 36 (b) shows a state in which pressure is applied to the container body 101. In this state, a fluid pressure due to the content liquid 104 is applied to the valve element 93 of the discharge member from the upstream side U, and the valve element 95 expands and deforms. 2 is released, and the content liquid 104 is discharged as a droplet 105. FIG. 38 is an enlarged view of the state of the discharge section 91 shown in FIG. 36 (b). FIG. 37 (a) is a continuation of the state shown in FIG. 36 (b). This shows a state in which pressurization of the container body 101 is stopped. In this state, the valve of the discharge member 9 3 Since the liquid pressure by the content liquid 104 is not applied to the valve, the valve body 93 is restored to the shape before pressurization, and the discharge hole 92 is closed again. Further, FIG. 37 (b) is a continuation of the state shown in FIG. 37 (a). By stopping the pressurization of the container main body 101, the container main body 101 becomes the shape before pressurization. Shows the state that is about to be restored. In this state, since the valve member 93 of the discharge member closes the discharge hole 92, the inflow of the outside air into the container body 101 is realized exclusively through the vent hole 96.
図 3 4に示す容器 1 0 0において、 吐出部材 9 0は、 内栓 1 0 3を介して 容器 1 0 0の首部 1 0 2に取り付けられている。 内栓 1 0 3は、 容器 1 0 0 の首部 1 0 2に摺動自在に揷嵌されるものであって、 図 3 4は、 容器 1 0 0 の使用状態における断面を示している。'内栓 1 0 3の先端部 1 0 3 aとフラ ンジ 9 9とが係合した状態 (すなわち、 未開栓状態) の態様と両者の係合に 伴う効果については、 図 3、 図 1 7、 図 2 7等に示す他の実施形態での場合 と同様である。  In the container 100 shown in FIG. 34, the discharge member 90 is attached to the neck 102 of the container 100 via the inner plug 103. The inner stopper 103 is slidably fitted to the neck portion 102 of the container 100, and FIG. 34 shows a cross section of the container 100 in a use state. Figure 3 and Figure 17 show the state in which the tip 103a of the inner plug 103 is engaged with the flange 99 (that is, the unplugged state) and the effect of the engagement of both. This is the same as in the other embodiments shown in FIGS.
図 3 5に示す吐出部材 9 0には、 その吐出部本体 9 1 aの外表面にキヤッ プ 1 0 6が螺設されている。 このキャップ 1 0 6は、 吐出部本体 9 l aと螺 合した状態でその吐出孔 9 2と相対する位置に凹陥部 1 0 8が設けられてお り、 当該凹陥部 1 0 8においてキャップ 1 0 6の内表面と吐出孔 9 2とが当 接している。 凹陥部 1 0 8の周囲にはスポンジ 1 0 7が設けられており、 吐 出孔 9 2に残存した残留液 1 0 5 ' (図 3 7 (b) 参照) は、 凹陥部 1 0 8に おけるキャップ内表面によって押しのけられて、 スポンジ 1 0 7にて吸収さ れる。  In the discharge member 90 shown in FIG. 35, a cap 106 is screwed on the outer surface of the discharge portion main body 91a. The cap 106 is provided with a recessed portion 108 at a position facing the discharge hole 92 in a state of being screwed with the discharge portion main body 9 la, and the cap 10 is formed in the recessed portion 108. The inner surface of 6 and the discharge hole 92 are in contact with each other. A sponge 107 is provided around the recess 108, and the residual liquid 105 ′ (see FIG. 37 (b)) remaining in the discharge hole 92 is formed in the recess 108. Is displaced by the cap inner surface and absorbed by the sponge 107.
図 3 5 (a) に示す吐出部材 9 0において、 キャップの開口端 1 0 6 aは吐 出部材 9 0の通気孔 9 6を塞いでいる。 この結果、 容器本体 1 0 1内に収容 された薬液の溶媒 (水) 等が通気フィルタ 9 7から徐々に蒸散して、 収容液 の p Hが変動してしまう、 といった問題が生じるのを防止することができる 図 3 9に示す、 第 5の吐出部材 9 0 ' についての他の実施形態では、 薄膜 部 9 3 aと弁体支持部 9 4 aとの当接だけでなく、 弁体 9 3, の弁本体部 9 3 b ' 力 弁体支持部材 9 4のフランジ部 9 4 bと当接することによつても 、 流路 9 5の閉鎖が実現されている。 従って、 弁体 9 3 ' によって流路 9 5 を閉鎖する作用を安定して発揮させることができ、 微生物、 埃等を含む残留 液が吐出孔 9 2から逆流するという事態が生じるのをより一層高度に防止す ることができる。 なお、 図 4 0は、 図 3 8に示す吐出部材 9 0 ' における吐 出部 9 1の状態を拡大して示すものである。 In the discharge member 90 shown in FIG. 35 (a), the open end 106a of the cap closes the ventilation hole 96 of the discharge member 90. As a result, it is possible to prevent a problem that the solvent (water) of the chemical solution contained in the container body 101 evaporates gradually from the ventilation filter 97 and the pH of the contained solution fluctuates. In another embodiment of the fifth discharge member 90 ′ shown in FIG. 39, not only the contact between the thin film portion 93a and the valve body support portion 94a but also the valve body 9 3, Valve body 9 3 b ′ Force The flow path 95 is also closed by contact with the flange portion 94 b of the valve body support member 94. Therefore, the action of closing the flow path 95 can be stably exhibited by the valve element 9 3 ′, and the situation in which the residual liquid containing microorganisms, dust, etc. flows backward from the discharge hole 92 further occurs. It can be highly prevented. FIG. 40 shows an enlarged view of the state of the discharge section 91 of the discharge member 90 ′ shown in FIG. 38.
上記第 5の吐出部材 9 0 , 9 0, においては、 流路 9 5の開閉位置 (薄膜 部 9 3 aと弁体支持部 9 4 aとの当接位置、 弁本体部 9 3 b ' とフランジ部 9 4 bとの当接位置) よりも上流側に、 通液フィルタ (図示せず) を設けて いてもよい。 通液フィルタを備えることに伴う効果については、 図 6、 図 1 8等に示す他の実施形態での場合と同様である。  In the fifth discharge members 90, 90, the open / close position of the flow passage 95 (the contact position between the thin film portion 93 a and the valve body support portion 94 a, the valve body portion 9 3 b ′) A liquid passage filter (not shown) may be provided upstream of the flange portion 94b (contact position with the flange portion 94b). The effect of providing the liquid passage filter is the same as in the other embodiments shown in FIGS. 6, 18 and the like.
第 5の吐出部材を備える容器 1 0 0において、 当該容器が点眼容器である 場合のように、 1回の吐出操作において 2 0〜4 0 μ L程度の液滴を吐出す ることが求められる用途に使用されるものである場合には、 弁体支持部 9 4 aの外径は 0 . 6〜2 . O mm、 好ましくは 1 . 0〜1 . 2 mmの範囲で設 定される。 また、 弁体 9 3の薄膜部 9 3 aにおける厚みは 0 . 8〜2 . 5 m m、 好ましくは 0 . 8〜1 . 5 mmの範囲で設定される。  In the case of the container 100 having the fifth ejection member, it is required that about 20 to 40 μL of droplets be ejected in one ejection operation, as in the case where the container is an eye drop container. When used for an application, the outer diameter of the valve body support portion 94a is set in the range of 0.6 to 2.0 mm, preferably 1.0 to 1.2 mm. The thickness of the valve body 93 at the thin film portion 93a is set in the range of 0.8 to 2.5 mm, preferably 0.8 to 1.5 mm.
吐出孔 9 2での液漏れを防止するという観点から、 弁体の薄膜部 9 3 aは 、 弁体支持部 9 4 aによって多少押し広げられた状態となっているのが好ま しい。 そこで、 弁体支持部 9 4 aを揷通させていない状態での薄膜部 9 3 a の内径は、 弁体支持部 9 4 aの外径よりも小さくなるように設定するのが好 ましい。 具体的には、 薄膜部 9 3 aの内径は、 弁体支持部 9 4 aの外径に対 して 5 0〜 9 9 %、 好ましくは 5 0〜 9 0 %、 より好ましくは 6 0〜 8 0 % となるように設定すればよい。 なお、 図 3 9に示すように、 弁体 9 3の薄膜 部 9 3 aと弁体支持部材 9 4の弁体支持部 9 4 aとの当接だけでなく、 弁体 9 3 ' の弁本体部 9 3 b, と弁体支持部材 9 4のフランジ部 9 4 bとの当接 によっても、 流路 9 5の閉鎖を実現している吐出部材 9 0 ' においては、 吐 出孔 9 2での液漏れの防止効果が高いことから、 薄膜部 9 3 aの内径を前述 した場合よりも緩やかに設計することができる。 次に、 本発明の吐出部材とそれを備える容器の各部について詳細に説明す る。 From the viewpoint of preventing the liquid from leaking at the discharge hole 92, it is preferable that the thin film portion 93a of the valve body is slightly expanded by the valve body support portion 94a. Therefore, it is preferable to set the inner diameter of the thin film portion 93a in a state where the valve body support portion 94a is not passed through so as to be smaller than the outer diameter of the valve body support portion 94a. . Specifically, the inner diameter of the thin film portion 93a is 50 to 99%, preferably 50 to 90%, more preferably 60 to 90% with respect to the outer diameter of the valve body support portion 94a. It should be set so as to be 80%. As shown in FIG. 39, not only the contact between the thin film portion 93a of the valve body 93 and the valve body support portion 94a of the valve body support member 94, but also the valve of the valve body 93 '. In the discharge member 90 ′ that realizes the closing of the flow passage 95 even by the contact between the main body portion 93 b and the flange portion 94 b of the valve body support member 94, the discharge hole 92 is formed. Therefore, the inner diameter of the thin film portion 93a can be designed more gently than in the case described above. Next, the discharge member of the present invention and each part of the container including the same will be described in detail.
(弁体)  (Valve)
本発明の吐出部材における弁体は、 容器本体側からの液圧によってかつ通 気フィルタの通液圧よりも低い液圧によって容易に圧縮または伸張変形し、 しかも通気フィルタの外部からの通気圧では圧縮または伸張変形を生じない ものであることが必要となる。 具体的に、 弁体に使用可能な材質としては、 低硬度の、 熱可塑性エラストマ一;ゲル状物質;天然ゴム、 シリコーンゴム 、 イソプレンゴム、 ブチルゴム、 ブタジエンゴム、 フッ素ゴム等のゴム類が 挙げられる。  The valve element of the discharge member according to the present invention is easily compressed or expanded by the liquid pressure from the container body side and by the liquid pressure lower than the liquid pressure of the gas filter, and furthermore, the gas pressure from the outside of the gas filter is low. It must be one that does not cause compression or extension deformation. Specifically, examples of materials usable for the valve body include low-hardness thermoplastic elastomers; gel-like substances; and rubbers such as natural rubber, silicone rubber, isoprene rubber, butyl rubber, butadiene rubber, and fluorine rubber. .
これらの材質のより具体的な種類については特に限定されるものではない 力 弁体の硬さは、 その伸張または圧縮変形についての上記特性を実現する ためにも、 J I S A硬度 〔J I S 6301 - 5. 2 「スプリング式 硬さ試験」 に記載の方法で測定したスプリング硬さ Hs (A型) 〕 で 0〜4 0の範囲にあることが求められる。 弁体の硬さ (J I S A) は、 上記範囲 の中でも特に J I S A30以下であるのが好ましく、 より好ましくは 20 以下、 さらに好ましくは 10以下である。 一方、 弁体の硬さ (J I S A) の下限は上記範囲よりもさらに限定されるものではないが、 材料の入手可能 性、 弁体の強度等の観点から、 J I S Aで 2以上であってもよい。  There is no particular limitation on the more specific types of these materials.The hardness of the force valve body is determined by the JISA hardness (JIS 6301-5. 2 The spring hardness Hs (A type) measured by the method described in “Spring hardness test” is required to be in the range of 0 to 40. The hardness (JISA) of the valve body is particularly preferably 30 or less, more preferably 20 or less, and still more preferably 10 or less in the above range. On the other hand, the lower limit of the hardness of the valve body (JISA) is not further limited than the above range, but from the viewpoint of material availability, strength of the valve body, etc., it may be 2 or more according to JISA. .
上記弁体の形成材料の具体例は次のとおりである。 熱可塑性エラストマ一 としては、 例えばスチレン一エチレン/ブチレン一スチレンブロック共重合 体 (SEB S) 、 スチレン一ブタジエン一スチレンブロック共重合体 (SB S) 、 スチレン一イソプレン一スチレンブロック共重合体 (S I S) 、 マレ ィン酸変性等の変性 S E B S、 スチレン一エチレン/プロピレン一スチレン プロック共重合体 (SEP S) 、 スチレン一エチレン/ブチレンブロック共 重合体 (SEB) 、 スチレン一エチレン/プロピレンプロック共重合体 (S E P) 等のスチレン系エラス トマ一;エチレン一プロピレンプロック共重合 体等のォレフィン系エラストマ一;ポリゥレタン系エラストマ一;およぴこ れらの混合物が挙げられる。 スチレン系の熱可塑性エラストマ一の中では、 例えばクラレプラスチックス (株) 製の 「セプトン (R) コンパウンド」 等が 好適である。 Specific examples of the material for forming the valve body are as follows. Examples of thermoplastic elastomers include styrene-ethylene / butylene-styrene block copolymer (SEB S), styrene-butadiene-styrene block copolymer (SB S), and styrene-isoprene-styrene block copolymer (SIS) , Maleic acid modified SEBS, styrene-ethylene / propylene-styrene block copolymer (SEPS), styrene-ethylene / butylene block copolymer (SEB), styrene-ethylene / propylene block copolymer (SEB) Styrene-based elastomers such as SEP); olefin-based elastomers such as ethylene-propylene block copolymer; polyurethane-based elastomers; and mixtures thereof. Among styrene-based thermoplastic elastomers, For example, "Septon (R) Compound" manufactured by Kuraray Plastics Co., Ltd. is suitable.
ゲル状物質としては、 例えば直鎖の炭化水素系高分子 (ォレフイン系エラ ストマー) からなるゲル 〔コスモ計器 (株) 製の 「コスモゲル」 など〕 ;シ リコーン一ウレタン系ゲノレ 〔ケミテック社製の商品名 「ケミテックゲル」 な ど〕 が挙げられる。  Examples of the gel-like substance include a gel composed of a linear hydrocarbon polymer (olefin elastomer) [such as “Cosmogel” manufactured by Cosmo Keiki Co., Ltd.); Name "Chemitec Gel".
弁体を形成する弾性体は、 発泡体 (但し、 孔が不連続であって、 液を通過 させないもの) であってもよく、 添加物によってその硬度を上記範囲に設定 したものであってもよレ、。  The elastic body forming the valve body may be a foamed body (provided that the pores are discontinuous and do not allow liquid to pass through), and even if the hardness is set to the above range by an additive. Yeah.
弁体の液圧による変形の程度を示す指標としては、 上記の硬さの他に、 例 えば弾性体の引張応力や圧縮弾性率等が挙げられる。 弁体に用いられる弾性 体は、 液圧の負荷、 除圧を繰り返し行っても破損することがないように、 そ の圧縮永久歪み率 C S ( J I S K 7301、 測定条件: 70°CX 22時 間) が 50以下であるのが好ましい。 また、 吐出部材が点眼容器の吐出部で ある場合において、 一般的な点眼動作での点眼液の滴下速度は 0. 05mL Z秒程度であることを考慮すれば、 弁体を圧縮または伸張変形させるのに要 する圧が、 0. 01〜0. 2MP a程度であるのが好ましい。  Indices indicating the degree of deformation of the valve element due to hydraulic pressure include, for example, tensile stress and compression elastic modulus of the elastic body in addition to the above hardness. The elastic body used for the valve body has its compression set CS (JISK 7301, measurement condition: 70 ° C x 22 hours) so that it will not be damaged by repeated application and removal of hydraulic pressure. Is preferably 50 or less. Also, in the case where the discharge member is the discharge part of the eye drop container, considering that the dropping speed of the eye drop in a general eye drop operation is about 0.05 mL Z seconds, the valve body is compressed or expanded and deformed. The pressure required for this is preferably about 0.01 to 0.2 MPa.
図 9および図 18に示す吐出部材 30, 30' のように、 弁体 33, 33 ' を吐出部 31の内表面 (31 e) に固定させる場合には、 上記例示の弾性 体材料の中から熱可塑性を有する材料を選択して、 弁体 33, 33' と吐出 部本体 31 aとを一体成形すればよい。  When the valve bodies 33, 33 'are fixed to the inner surface (31e) of the discharge portion 31 as in the discharge members 30, 30' shown in FIGS. A material having thermoplasticity may be selected, and the valve bodies 33, 33 'and the discharge portion main body 31a may be integrally formed.
図 28に示す吐出部材 70のように、 吐出部本体 71 aの吐出孔 72部分 に取り付ける場合には、 上記例示の弾性体材料中から熱可塑性を有する材料 を選択して、 弁体 73と、 吐出部本体 71 aとを一体成形すればよい。  When the discharge member 70 is attached to the discharge hole 72 of the discharge portion main body 71a as shown in FIG. 28, a material having thermoplasticity is selected from the above-described elastic materials, and a valve body 73, What is necessary is just to integrally mold the discharge part main body 71a.
一方、 弁体を、 図 32に示す吐出部材 70' のように、 吐出部本体 71 a ' と弁座 74に連設する筒体 74 aとの間に挟持させるなどして、 吐出部 7 0' に配置する場合には、 弁体形成用の弾性体材料は、 熱可塑性を有する材 料に限定されるものではない。  On the other hand, as shown in a discharge member 70 ′ shown in FIG. 32, the discharge portion 70 is sandwiched between a discharge portion main body 71 a ′ and a cylindrical body 74 a connected to the valve seat 74, so that the discharge portion 70 In the case where the elastic body material is formed at the position ′, the elastic material for forming the valve body is not limited to a material having thermoplasticity.
(通気フィルタ) 本発明に用いられる通気フィルタは、 前述のように、 その通液圧が、 吐出 部材の弁体変形の態様は圧縮と伸張の 2通りを生じる圧を超えるものであり 、 かつその外部からの通気圧が、 吐出孔を開放する圧を下回るものであるこ とが求められる。 (Ventilation filter) As described above, the ventilation filter used in the present invention has a liquid passing pressure exceeding a pressure that causes two forms of compression and expansion in the deformation of the valve body of the discharge member, and a flow from the outside. It is required that the pressure be lower than the pressure at which the discharge port is opened.
吐出部材の弁体変形の態様は圧縮と伸張の 2通りを生じさせて内容液等を 吐出させるのに必要な液圧は、 吐出動作の速度 (吐出される液滴の滴下速度 ) に応じて変動するものであることから、 通気フィルタに求められる通液圧 や通気圧も、 吐出部材の用途や一般に想定される吐出動作の速度等に応じて 設定する必要がある。  There are two modes of deformation of the valve body of the discharge member, compression and expansion, and the fluid pressure required to discharge the content liquid, etc., depends on the speed of the discharge operation (the dripping speed of the discharged droplets). Since it fluctuates, it is necessary to set the liquid pressure and the air pressure required for the ventilation filter according to the use of the discharge member, the generally assumed speed of the discharge operation, and the like.
具体的に、 吐出部材が点眼容器の吐出部である場合において、 一般的な点 眼動作での点眼液の滴下速度は 0. 05 m LZ秒程度であって、 その場合に 弁体変形の態様は圧縮または Zおよび伸張を生じさせて点眼液を滴下させる のに要する圧は 0. 01〜0. 2 MP a程度であることから、 通気フィルタ の通液圧が少なくとも 0. 0 IMP a、 好ましくは 0. 2MP aを超えるも のであれば、 点眼動作の際に通気孔から点眼液が漏れ出すのを防止すること ができる。  Specifically, when the discharge member is the discharge part of the eye drop container, the drop rate of the eye drop in a general eye drop operation is about 0.05 mLZ second, and in that case, the shape of the valve body deformation Since the pressure required to cause the ophthalmic solution to drip by causing compression or Z and expansion is about 0.01 to 0.2 MPa, the liquid pressure of the ventilation filter is at least 0.0 IMPa, and is preferable. If the pressure exceeds 0.2 MPa, it is possible to prevent the ophthalmic solution from leaking from the vent during the eye dropping operation.
また、 一般的な点眼動作で点眼液を滴下した後に、 点眼容器内へと空気を 流入させる速度 (吸気速度) は 1〜1 OmL/秒程度となる。 ここで、 通気 フィルタの通気圧が少なくとも 0. 005MP aを下回るもの、 好ましくは 0. 00 IMP aを下回るものであれば、 通気孔からのスムーズな外気導入 を達成することができる。  In addition, the rate at which air flows into the eyedropper (inhalation speed) after dropping eyedrops in a general eyedropping operation is about 1 to 1 OmL / sec. Here, if the ventilation pressure of the ventilation filter is at least lower than 0.005 MPa, preferably lower than 0.005 IMPa, smooth introduction of outside air from the ventilation hole can be achieved.
通気フィルタの孔径は、 本発明の吐出部材によって吐出される液体 (本発 明の容器に収容される薬液等の内容液) や、 細菌等の微生物や空気中の埃、 塵等を通過させず、 空気のみを通過させることのできる範囲に設定されるも のであって、 通常、 0. 1〜0. 45 μιη、 好ましくは 0. Ι μπι程度に設 定される。  The pore size of the ventilation filter is set so that the liquid (content liquid such as a chemical solution contained in the container of the present invention) discharged by the discharge member of the present invention, microorganisms such as bacteria, dust in the air, dust and the like do not pass. It is set to a range that allows only air to pass through, and is usually set to about 0.1 to 0.45 μιη, preferably to about 0.1 μμπι.
本発明に使用可能な通気フィルタとしては、 これに限定されるものではな いが、 例えばジャパンゴァテックス社の疎水性ポリテトラフルォロエチレン (PTFE) 膜、 日本ミリポア社の S u r e Ve n t デユラポア(R) 〔 ポリフッ化ビニリデン (P V D F ) 製〕 等が挙げられる。 Examples of the aeration filter usable in the present invention include, but are not limited to, hydrophobic polytetrafluoroethylene (PTFE) membrane of Japan Gore-Tex Co., Ltd., and Sure Vent of Japan Millipore Co., Ltd. Dyurapore (R) [ Made of polyvinylidene fluoride (PVDF)].
(通液フィルタ)  (Liquid flow filter)
本発明に用いられる通液フィルタは、 一定以上の液圧を付加することによ つて液体の透過が許容されるフィルタである。 かかる通液フィルタを吐出孔 の上流側に設けた場合には、 前述のように、 万一、 吐出孔の残留液が逆流す るような事態が生じたとしても、 当該残留液が吐出部材に連結される容器本 体にまで侵入するのを当該フィルタによって阻止することができる。  The liquid passing filter used in the present invention is a filter that allows liquid permeation by applying a certain or more liquid pressure. In the case where such a liquid passage filter is provided on the upstream side of the discharge hole, as described above, even in the event that the residual liquid in the discharge hole flows backward, the residual liquid is applied to the discharge member. The filter can prevent entry into the connected container body.
本発明に使用可能な通液フィルタとしては、 これに限定されるものではな いが、 例えばジャパンゴァテックス社の親水性 P T F E膜、 日本ミリポア社 の親水性デユラポア(R) ( P V D F製) 、 同社の親水性ポリエーテルスルホ ン (P E S ) 膜等が挙げられる。  Examples of the liquid passage filter usable in the present invention include, but are not limited to, hydrophilic PTFE membrane of Japan Gore-Tex Co., Ltd., hydrophilic Durapore (R) (manufactured by Nippon Millipore) (PVDF), The company's hydrophilic polyethersulfone (PES) membrane is an example.
〔キャップ〕  [Cap]
本発明の吐出部材においては、 吐出孔への抗菌処理と併せて、 またはこれ に代えて、 吐出部の外表面に被せるキャップに抗菌処理を施してもよい。 抗 菌処理の対象となるキャップの部位は、 これに限定されるものではないが、 その内表面のうち吐出孔と接する部位、 またはキヤップの内部に配置される スポンジ等が挙げられる。  In the discharge member of the present invention, the antibacterial treatment may be performed on the cap placed on the outer surface of the discharge part together with or instead of the antibacterial treatment on the discharge holes. The part of the cap to be subjected to the antibacterial treatment is not limited to this, but may be a part of the inner surface that is in contact with the discharge hole, a sponge disposed inside the cap, or the like.
本発明の吐出部材は、 吐出孔側から上流側への逆流を生じないものである ことから、 吐出操作を終えた後の残留液は、 吐出部内に流入せずに、 吐出孔 の周りに残存することになる。 そこで、 例えば内部に吸収材を備えるキヤッ プを使用して、 吐出操作を終えた後に吐出孔近傍に滞留する内容液 (残留液 ) を吸収材で吸い取らせることによって、 再度の滴下操作の際に当該残留液 が吐出されないようにすることができる (図 1 7および図 2 7参照) 。  Since the discharge member of the present invention does not cause a backflow from the discharge hole side to the upstream side, the residual liquid after the discharge operation does not flow into the discharge part but remains around the discharge hole. Will do. Therefore, for example, using a cap with an absorbing material inside, the content liquid (residual liquid) that stays in the vicinity of the discharge hole after the discharging operation is sucked up by the absorbing material, so that when the dropping operation is performed again, The residual liquid can be prevented from being discharged (see Figs. 17 and 27).
スポンジに抗菌処理を施して、 これを吐出孔に直接接触させた場合には、 経時的にスポンジから抗菌剤が滲出して、 吐出孔に付着するおそれがある。 そこで、 スポンジと吐出孔とを直接に接触させずに、 キャップの内表面で押 しのけられた吐出孔の残留液がキヤップ内表面の周囲に設けられた吸収材に 吸収されるように設計してもよい (図 3 5参照) 。  If an antibacterial treatment is applied to the sponge and the sponge is brought into direct contact with the discharge port, the antibacterial agent may ooze out of the sponge with time and adhere to the discharge port. Therefore, the sponge is designed so that the sponge does not come into direct contact with the spout, and the residual liquid in the spout, which has been pushed away on the inner surface of the cap, is absorbed by the absorbent material provided around the inner surface of the cap. (See Figure 35).
吸収材の具体例としては、 例えばウレタンや発泡ポリエチレン等からなる スポンジ;不織布、 脱脂綿、 ガーゼ等からなる布地;紙、 ヒドロゲル等が挙 げられる。 スポンジの形成には、 例えばウレタンや発泡ポリエチレン等の、 従来公知の種々の材料を用いればよい。 スポンジに抗菌処理を施すには、 例 えばスポンジ作製後に当該薬剤を塗布等の手段によってスポンジの表面に付 着させたり、 ウレタンやポリエチレンに抗菌剤等の薬剤をあらかじめ練り込 んだりしておくのが好ましい。 また、 吸収材の素材自体にあらかじめ抗菌性 を有するものを用いてもよい。 Specific examples of the absorbent include, for example, urethane and foamed polyethylene. Sponge; cloth made of non-woven fabric, absorbent cotton, gauze; etc .; paper, hydrogel and the like. Various known materials such as urethane and foamed polyethylene may be used for forming the sponge. To apply an antibacterial treatment to a sponge, for example, after the sponge is prepared, the agent is attached to the surface of the sponge by means such as coating, or a drug such as an antibacterial agent is mixed in urethane or polyethylene in advance. Is preferred. Also, a material having antibacterial properties may be used in advance as the material of the absorbent.
上記布、 紙、 ヒドロゲル等に対する抗菌処理としては、 例えばこれらにシ ラン力ップリングゃセレニウムコーティング等の処理を施す方法が挙げられ る。 ヒドロゲルの具体例としては、 例えば (メタ) アクリルアミド系等の高 分子と水膨潤性粘土鉱物とを組み合わせてなるもの (特開 2 0 0 2 - 5 3 6 2 9号公報、 特開 2 0 0 2 - 5 3 7 6 2号公報) が挙げられる。  Examples of the antibacterial treatment on the cloth, paper, hydrogel, and the like include a method of subjecting them to treatment such as silane coupling and selenium coating. Specific examples of the hydrogel include, for example, those obtained by combining a high molecule such as (meth) acrylamide and a water-swellable clay mineral (Japanese Patent Application Laid-Open No. 2002-53036, Japanese Patent Application Laid-Open No. 200-200). 2-5 3 7 6 2).
(吐出部材、 キヤップぉよび容器本体の形成材料)  (Discharge member, material for forming cap and container body)
吐出部材、 キャップおよび容器本体を形成する樹脂としては、 例えばポリ エチレン (P E ) 、 ポリプロピレン (P P ) 等が挙げられる。 特に P Eや P Pは医薬的に安全な素材であることから、 本発明の容器が点眼容器のような 薬液を収容するものである場合に特に好適である。  Examples of the resin forming the ejection member, the cap, and the container body include polyethylene (PE) and polypropylene (PP). In particular, since PE and PP are pharmaceutically safe materials, they are particularly suitable when the container of the present invention contains a drug solution such as an ophthalmic container.
吐出部材、 キャップおよび容器本体を形成する樹脂には、 吐出操作後にお Vヽて吐出孔の近傍などに残存する液や、 容器本体内に収容される内容液につ いての腐敗等を防止する効果をより一層高めるという観点から、 あらかじめ 防腐剤等を練り込んでおいてもよい。 防腐剤の具体例としては、 第 4級アン モニゥム塩 〔例えば、 ィヌィ (株) 製の商品名 「ダイマー 3 8 (R) 」 、 同社 製の 「ダイマー 1 3 6 (R) 」 〕 等が挙げられる。  The resin that forms the discharge member, cap and container body prevents liquid remaining in the vicinity of the discharge hole after the discharge operation and decay of the content liquid contained in the container body. From the viewpoint of further enhancing the effect, a preservative or the like may be previously kneaded. Specific examples of preservatives include quaternary ammonium salts [for example, “Dimmer 38 (R)” manufactured by Iny Corporation, and “Dimmer 13 36 (R)” manufactured by the company). Can be
また、 吐出部材、 キャップおよび容器本体の形成後に、 その内表面等に防 腐剤を塗布等の手段によって付着させたり、 吐出部材、 キャップおよび容器 本体の形成時にシランカップリングなどによる表面処理を施しておいたりし てもよい。 吐出部等を形成する樹脂の素材自体に抗菌活性を有するものを用 いてもよい。 図面の簡単な説明 After the discharge member, cap and container body are formed, a preservative is applied to the inner surface and the like by applying a means such as coating, or a surface treatment such as silane coupling is performed when forming the discharge member, cap and container body. You may put it. A material having antibacterial activity may be used as a resin material itself for forming the ejection portion and the like. BRIEF DESCRIPTION OF THE FIGURES
図 1は、 第 1の吐出部材の一実施形態を示す断面図である。  FIG. 1 is a cross-sectional view showing one embodiment of the first ejection member.
図 2は、 第 1の吐出部材を備える容器の一実施形態を示す断面図である。 図 3は、 図 2に示す容器の未開栓状態を示す断面図である。  FIG. 2 is a cross-sectional view illustrating an embodiment of the container including the first discharge member. FIG. 3 is a cross-sectional view showing an unopened state of the container shown in FIG.
図 4は、 図 2に示す容器の使用状態を示す断面図である。  FIG. 4 is a cross-sectional view showing a use state of the container shown in FIG.
図 5は、 図 4の続きを示す断面図である。  FIG. 5 is a sectional view showing a continuation of FIG.
図 6は、 第 1の吐出部材を備える容器の他の実施形態を示す断面図である 図 7は、 第 1の吐出部材の他の実施形態を示す断面図である。  FIG. 6 is a cross-sectional view illustrating another embodiment of the container including the first discharge member. FIG. 7 is a cross-sectional view illustrating another embodiment of the first discharge member.
図 8は、 第 1の吐出部材のさらに他の実施形態を示す断面図である。  FIG. 8 is a sectional view showing still another embodiment of the first discharge member.
図 9は、 第 2の吐出部材の一実施形態を示す断面図である。  FIG. 9 is a sectional view showing an embodiment of the second ejection member.
図 1 0は、 図 9に示す吐出部材 3 0を分解した状態を示す断面図である。 図 1 1 (a) は吐出部本体 3 1 aと弁体 3 3との一体成形物の一例を示す平 面図、 図 1 1 (b) はその底面図である。  FIG. 10 is a cross-sectional view showing a state where the ejection member 30 shown in FIG. 9 is disassembled. FIG. 11 (a) is a plan view showing an example of an integrally formed product of the discharge portion main body 31a and the valve body 33, and FIG. 11 (b) is a bottom view thereof.
図 1 2 (a) は弁座部 3 4の平面図、 図 1 2 (b) はその底面図である。  FIG. 12 (a) is a plan view of the valve seat portion 34, and FIG. 12 (b) is a bottom view thereof.
図 1 3 (a) は吐出部本体と弁体との一体成形物の他の例を示す平面図、 図 Fig. 13 (a) is a plan view showing another example of an integrally molded product of the discharge part main body and the valve body,
1 3 (b) は弁座部の他の例を示す平面図である。 13 (b) is a plan view showing another example of the valve seat.
図 1 4は、 第 2の吐出部材を備える容器の一実施形態を示す断面図である 図 1 5は、 図 1 4に示す容器の使用状態を示す断面図である。  FIG. 14 is a cross-sectional view showing an embodiment of the container provided with the second discharge member. FIG. 15 is a cross-sectional view showing a use state of the container shown in FIG.
図 1 6は、 図 1 5の続きを示す断面図である。  FIG. 16 is a cross-sectional view showing a continuation of FIG.
図 1 7は、 図 1 4に示す容器 4 0の未開栓状態を示す断面図である。  FIG. 17 is a cross-sectional view showing an unopened state of the container 40 shown in FIG.
図 1 8は、 第 2の吐出部材の他の実施形態を示す断面図である。  FIG. 18 is a cross-sectional view showing another embodiment of the second ejection member.
図 1 9は、 第 3の吐出部材の一実施形態を示す断面図である。  FIG. 19 is a sectional view showing an embodiment of the third ejection member.
図 2 0は、 図 1 9に示す吐出部材 5 0の分解断面図である。  FIG. 20 is an exploded sectional view of the discharge member 50 shown in FIG.
図 2 1は、 図 2 0に示す吐出部本体 5 1 aの平面図である。  FIG. 21 is a plan view of the discharge unit main body 51 a shown in FIG.
図 2 2は(a) は、 図 2 0に示す弁体支持部材 5 4の平面図、 図 2 2 (b) は その底面図である。  22 (a) is a plan view of the valve element supporting member 54 shown in FIG. 20, and FIG. 22 (b) is a bottom view thereof.
図 2 3は、 図 1 9に示す吐出部材 5 0の組み立て方法を示す説明図である 図 2 4は、 図 1 9の吐出部材 5 0を備える容器の一例を示す断面図である 図 2 5は、 図 2 4に示す容器 6 0の使用状態を示す断面図である。 FIG. 23 is an explanatory view showing a method of assembling the discharge member 50 shown in FIG. FIG. 24 is a cross-sectional view illustrating an example of a container including the discharge member 50 of FIG. 19. FIG. 25 is a cross-sectional view illustrating a use state of the container 60 illustrated in FIG.
図 2 6は、 図 2 5の続きを示す断面図である。  FIG. 26 is a cross-sectional view showing a continuation of FIG.
図 2 7は、 図 2 4に示す容器 6 0の未開栓状態を示す断面図である。  FIG. 27 is a cross-sectional view showing the container 60 shown in FIG. 24 in an unopened state.
図 2 8は、 第 4の吐出部材の一実施形態を示す断面図である。  FIG. 28 is a cross-sectional view illustrating an embodiment of the fourth ejection member.
図 2 9 (a) は図 2 8に示す吐出部材 7 0の底面図、 図 2 9 (b) は A— A断 面図である。  FIG. 29 (a) is a bottom view of the discharge member 70 shown in FIG. 28, and FIG. 29 (b) is a sectional view taken along the line AA.
図 3 0 (a) は第 4の吐出部材 7 0を備える容器の一例を示す断面図、 図 3 0 (b) はその使用状態を示す断面図である。  FIG. 30 (a) is a cross-sectional view showing an example of a container provided with a fourth discharge member 70, and FIG. 30 (b) is a cross-sectional view showing the state of use.
図 3 1は、 図 3 0 (b) の続きを示す断面図である。  FIG. 31 is a cross-sectional view showing a continuation of FIG. 30 (b).
図 3 2は、 本発明に係る第 4の吐出部材の他の実施形態を示す断面図であ る。  FIG. 32 is a sectional view showing another embodiment of the fourth ejection member according to the present invention.
図 3 3は、 第 5の吐出部材の一実施形態を示す断面図である。  FIG. 33 is a cross-sectional view illustrating an embodiment of the fifth ejection member.
図 3 4は、 第 5の吐出部材を備える容器の一実施形態を示す断面図である 図 3 5 (a) は図 3 4に示す容器 1 0 0にキヤップを取り付けた状態を示す 断面図であって、 図 3 5 (b) は当該キャップを示す断面図である。  FIG. 34 is a cross-sectional view showing an embodiment of a container provided with a fifth discharge member. FIG. 35 (a) is a cross-sectional view showing a state where a cap is attached to the container 100 shown in FIG. FIG. 35 (b) is a sectional view showing the cap.
図 3 6は、 図 3 4に示す容器の使用状態を示す断面図である。  FIG. 36 is a cross-sectional view showing a use state of the container shown in FIG.
図 3 7は、 図 3 6の続きを示す断面図である。  FIG. 37 is a cross-sectional view showing a continuation of FIG.
図 3 8は、 図 3 6 (b) に示す容器 1 0 0の吐出部を示す拡大断面図である 図 3 9は、 第 5の吐出部材の他の実施形態を示す断面図である。  FIG. 38 is an enlarged cross-sectional view showing the discharge section of the container 100 shown in FIG. 36 (b). FIG. 39 is a cross-sectional view showing another embodiment of the fifth discharge member.
図 4 0は、 図 3 9に示す容器 1 0 0 ' の使用状態における吐出部の拡大断 面図である。  FIG. 40 is an enlarged cross-sectional view of the discharge section in the use state of the container 100 ′ shown in FIG.
図 4 1 (a) は従来の点眼容器の一例を示す正面図、 図 4 1 (b) はその吐出 部材の拡大断面図である。  FIG. 41 (a) is a front view showing an example of a conventional eye drop container, and FIG. 41 (b) is an enlarged sectional view of the discharge member.
図 4 2は、 従来の点眼容器における問題点を示す説明図である。 符号の説明 FIG. 42 is an explanatory view showing a problem in a conventional eye drop container. Explanation of reference numerals
1 0, 1 0' , 1 0 a 30, 30' , 50, 70, 70 ' , 9 , 90' 吐出部材 1 0, 1 0 ', 1 0 a 30, 30', 50, 70, 70 ', 9, 90' Discharge member
1 1, 3 1, 5 1, 7 9 1 吐出部 1 1, 3 1, 5 1, 7 9 1 Discharge section
l i d 吐出部内表面 l i d Inner surface of discharge section
1 2, 3 2, 5 2, 7 吐出孔 1 2, 32, 52, 7 Discharge hole
1 3, 1 3 a, 1 3 b 3 3 ' 5 3 7 3, 7 3 9 3, 9 3 弁体 1 3, 1 3 a, 1 3 b 3 3 '5 3 7 3, 7 3 9 3, 9 3 Valve element
1 4 繋止部  1 4 Locking part
1 5, 3 5, 5 5, 7 5 , 9 5 流路  1 5, 3 5, 55, 75, 95
1 6 , 3 6, 56, 7 6 , 9 6 通気孔  16, 36, 56, 76, 96 Vent
1 7, 3 7, 5 7, 7 7 , 9 7 通気フィルタ  1 7, 3 7, 5 7, 7, 7, 9 7 Ventilation filter
1 8, 3 8, 58, 7 8 通液フィルタ  1 8, 3 8, 58, 7 8 Flow-through filter
2 0, 20 ' , 40 6 0 , 80, 1 00 容器 (点眼器)  20, 20 ', 4060, 80, 100 containers (eye drops)
2 1, 4 1, 6 1, 8 1 , 1 0 1 容器本体  2 1, 41, 61, 81, 101 Container body
2 3, 43, 6 3, 8 3 , 1 0 3 内栓  2, 3, 43, 63, 83, 103 Inner plug
2 4, 44, 64, 8 4 , 1 04 内容液  2, 4, 44, 64, 84, 104 Contents liquid
2 5, 45, 6 5, 8 5 , 1 05 液滴  2 5, 45, 65, 85, 105 Droplet
2 5, , 45 , , ,  25,,,,,,
6 5 , 8 5' , 1 0 5' 残留液  65, 85 ', 105' Residual liquid
2 6, 46, 6 6, 1 0 6 キャップ  2, 6, 46, 66, 106 cap
3 4 a , 34 a ' , 7 4 弁座  3 4 a, 34 a ', 7 4 Valve seat
5 2 a 流路内壁  5 2 a Inner wall of flow passage
5 2 b 凸条  5 2 b ridge
5 3 a 弁本体部  5 3a Valve body
5 3 b 突起  5 3 b protrusion
9 3 a 薄肉部  9 3a Thin section
9 3 b 弁本体部  9 3 b Valve body
9 4 a 弁体支持部  9 4a Valve support
9 4 b フランジ部 U 上流側 9 4 b Flange U Upstream
D 下流側 産業上の利用可能性  D Downstream Industrial availability
本発明の吐出部材によれば、 吐出孔から吐出された液体の逆流およびそれ に伴う微生物や埃等の上流側への侵入を高度に防止しつつ、 吐出処理と吐出 操作後における容器の復元とをスムーズに行うことができる。  ADVANTAGE OF THE INVENTION According to the discharge member of this invention, while the backflow of the liquid discharged from the discharge hole and the invasion of microorganisms, dust, etc. accompanying the discharge to the upstream side are highly prevented, the discharge processing and the restoration of the container after the discharge operation are performed Can be performed smoothly.
本発明の吐出部材において、 弁体の変形は通気フィ^^タの通液圧よりも低 い液圧によって達成されることから、 吐出操作の際に通気孔において液漏れ を生じることがなく、 確実に吐出孔からの吐出を実現することができる。 し かも、 吐出孔ぉよび/または吐出孔につながる流路の開放は通気フィルタへ の外部からの通気圧では達成されないことから、 容器本体の復元時に通気孔 ではなく吐出孔から外気が流入するといつた問題や、 これに伴って吐出孔か ら内容液が漏れ出すといった問題を生じることがない。 従って、 本発明の吐 出部材によれば、 吐出孔から吐出された液体の逆流およびそれに伴う微生物 や埃等の上流側への侵入を高度に防止しつつ、 吐出処理と吐出操作後におけ る容器の復元とをスムーズに行うことができる。  In the discharge member of the present invention, since the deformation of the valve body is achieved by a liquid pressure lower than the liquid pressure of the ventilation filter, no liquid leakage occurs in the ventilation hole during the discharge operation, Discharge from the discharge hole can be reliably realized. In addition, since the opening of the discharge port and / or the flow path leading to the discharge port cannot be achieved by the external ventilation pressure to the ventilation filter, when outside air flows in through the discharge port instead of the ventilation port when the container body is restored. This does not cause the problem that the liquid content leaks from the discharge hole. Therefore, according to the ejection member of the present invention, the container after the ejection process and the ejection operation can be highly prevented while the backflow of the liquid ejected from the ejection hole and the accompanying invasion of microorganisms and dust to the upstream side are highly prevented. Restoration can be performed smoothly.
なお、 本発明の吐出部材は、 前述の特開 2 0 0 1— 1 7 9 0 1 7号公報 ( 日本) ゃ特開 2 0 0 1— 2 0 6 4 5 4号公報 (日本) 記載の抗菌性容器のよ うに、 吐出部に多孔性フィルタを配置したものではないことから、 例えば内 容液が懸濁液のような場合であつても吐出孔に目詰まりが生じるおそれが極 めて低い。 弁体や吐出孔の大きさ、 材質等によって異なるものの、 通常、 懸 濁粒子の粒径が 5 0 m程度までであれば、 吐出孔で目詰まりを生じること がない。  Note that the discharge member of the present invention is described in JP-A-201-17990 (Japan) ゃ JP-A 201-204654 (Japan) described above. Unlike an antimicrobial container, a porous filter is not provided at the discharge section, so there is a very low risk of clogging of the discharge holes even when the liquid content is a suspension, for example. Low. Although it depends on the size, material, etc. of the valve body and the discharge port, clogging does not usually occur in the discharge port if the particle size of the suspended particles is up to about 50 m.
本発明の容器は、 その口部に本発明の吐出部材を備えるものであることか ら、 一旦吐出された内容液が容器本体に逆流したり、 それに伴って細菌等の 微生物や埃、 塵等が容器本体内へ侵入したりするのを高度に防止することが でき、 それゆえ、 内容液の腐敗または劣化を防止するための薬剤 (例えば防 腐剤) の配合をなくすこと、 またはその配合を極力少なくすることができる 。 また、 本発明の容器は吐出部に多孔性フィルタを用いるものではなく、 そ れゆえ吐出孔での目詰まりを生じることがないことから、 吐出孔の上流側に 通液フィルタを備える場合以外は、 たとえ内容液が懸濁液であってもスムー ズな吐出を実現することができる。 Since the container of the present invention is provided with the discharge member of the present invention at the mouth thereof, the liquid once discharged flows back into the container body, and accordingly, microorganisms such as bacteria, dust, dust, etc. Can be prevented from penetrating into the body of the container, and therefore, the use of chemicals (for example, preservatives) to prevent spoilage or deterioration of the content liquid is eliminated, or the use of such chemicals is not required. Can be reduced as much as possible . Further, the container of the present invention does not use a porous filter in the discharge portion, and therefore does not cause clogging in the discharge hole. However, even if the content liquid is a suspension, smooth discharge can be realized.
本発明の容器はさらに、 吐出部材の流路内または容器本体内において摺動 自在に保持される内栓を備え、 当該内栓が、 容器の未使用時に吐出部材の流 路内壁と当接して流路を閉鎖するものであるのが好ましい。 この場合、 容器 の使用を開始するまでは気密的に内容液の無菌状態を保証することができ、 しかも未使用状態では内容液が弁体や通気フィルタと接触するのを防止でき ることから、 長期間に亘つて品質を安定させることができる。 本発明の容器 は、 例えば点眼液を収容する点眼容器として好適である。  The container of the present invention further includes an inner plug slidably held in the flow path of the discharge member or in the container body, and the inner plug comes into contact with the inner wall of the flow path of the discharge member when the container is not used. Preferably, the flow path is closed. In this case, the sterile condition of the content liquid can be guaranteed airtight until the container is started to be used, and the content liquid can be prevented from contacting the valve element and the ventilation filter when not in use. Quality can be stabilized over a long period of time. The container of the present invention is suitable, for example, as an ophthalmic container for storing an ophthalmic solution.

Claims

請求の範囲 The scope of the claims
1 . 底部に吐出孔を備える有底略筒状または略椀状の吐出部と、 上記吐出孔側を下流側としたときに、 上流側から液圧を受けていない状態 で上記吐出孔および Zまたは当該吐出孔につながる吐出部内の流路を閉鎖し 、 かつ上流側から液圧を受けると変形して当該吐出孔ぉよび Zまたは流路を 開放する、 弾性体からなる弁体と、  1. A bottomed substantially cylindrical or bowl-shaped discharge portion having a discharge hole at the bottom, and the discharge hole and the Z in a state where the discharge hole side is the downstream side and not receiving the hydraulic pressure from the upstream side. Or a valve body made of an elastic body, which closes a flow passage in the discharge portion connected to the discharge hole, and deforms when receiving a hydraulic pressure from the upstream side to open the discharge hole and Z or the flow passage;
通気フィルタを介して上記弁体よりも上流側の流路につながる通気孔と、 を備え、  A vent hole connected to a flow path on the upstream side of the valve body through a ventilation filter,
上記弁体の変形が上記通気フィルタの通液圧よりも小さい液圧によって達 成されかつ上記吐出孔および Zまたは上記流路の開放が、 上記通気フィルタ への外部からの通気圧では達成されないものである吐出部材。  The deformation of the valve body is achieved by a fluid pressure smaller than the fluid pressure of the ventilation filter, and the opening of the discharge hole and the Z or the flow path is not achieved by an external ventilation pressure to the ventilation filter. Discharge member.
2 . 底部に吐出孔を備える有底略筒状または略椀状の吐出部と、 当該吐出部内に配置されて、 上記吐出孔側を下流側としたときに上流側か ら液圧を受けていない状態で上記吐出孔を閉鎖し、 かつ上流側から液圧を受 けると圧縮変形して当該吐出孔を開放する、 弾性体からなる弁体と、  2. A bottomed substantially cylindrical or bowl-shaped discharge portion having a discharge hole at the bottom, and is disposed in the discharge portion, and receives the hydraulic pressure from the upstream side when the discharge hole side is the downstream side. A valve body made of an elastic body, which closes the discharge hole in a state where the discharge hole is not provided, and compresses and deforms when the hydraulic pressure is received from the upstream side to open the discharge hole.
上記吐出部の内部に配置されて吐出部内表面との間に流路を区画しかつ上 流側において上記弁体を固定する繋止部と、  A locking part disposed inside the discharge part to partition a flow path between the discharge part and an inner surface thereof and to fix the valve body on the upstream side;
通気フィルタを介して上記弁体よりも上流側の流路とつながる通気孔と、 を備え、  A vent that is connected to a flow path on the upstream side of the valve body through a vent filter,
上記弁体の圧縮変形が上記通気フィルタの通液圧よりも小さい液圧によつ て達成されかつ上記吐出孔および/または上記流路の開放が、 上記通気フィ ルタへの外部からの通気圧では達成されないものである吐出部材。  The compression deformation of the valve body is achieved by a hydraulic pressure lower than the hydraulic pressure of the ventilation filter, and the opening of the discharge port and / or the flow path is controlled by the external ventilation pressure to the ventilation filter. A discharge member that cannot be achieved by the above.
3 . 上記弁体と上記繋止部とを一体成形してなる請求項 2記載の吐出部材 3. The discharge member according to claim 2, wherein the valve body and the locking portion are integrally formed.
4 . 底部に吐出孔を備える有底略筒状または略椀状の吐出部と、 当該吐出部内に固定されてなる弁座と、 4. A bottomed substantially cylindrical or bowl-shaped discharge portion having a discharge hole at the bottom, a valve seat fixed in the discharge portion,
上記吐出部の内表面に固定されて、 上記吐出孔を下流側としたときに、 液 圧を受けていない状態で上記弁座に下流側から当接して当該吐出孔につなが る流路を閉鎖し、 かつ上流側から液圧を受けると圧縮変形して当該弁座との 間に流路を開放する、 弾性体からなる略筒状の弁体と、 When the discharge port is fixed to the inner surface of the discharge section and the discharge port is located on the downstream side, the flow path connected to the discharge port is closed by contacting the valve seat from the downstream side without receiving the hydraulic pressure. And when it receives hydraulic pressure from the upstream side, it compresses and deforms, A substantially cylindrical valve body made of an elastic body, with a flow path opened between
通気フィルタを介して上記弁体よりも上流側の流路とつながる通気孔と、 を備 、  A ventilation hole connected to a flow path on the upstream side of the valve body through a ventilation filter;
上記弁体の圧縮変形が上記通気フィルタの通液圧よりも小さい液圧によつ て達成されかつ上記吐出孔および Zまたは上記流路の開放が、 上記通気フィ ルタへの外部からの通気圧では達成されないものである吐出部材。  The compressive deformation of the valve body is achieved by a hydraulic pressure lower than the hydraulic pressure of the ventilation filter, and the opening of the discharge port and Z or the flow path is controlled by the external ventilation pressure to the ventilation filter. A discharge member that cannot be achieved by the above.
5. 上記弁体と上記吐出部とを一体成形してなる請求項 4記載の吐出部材  5. The discharge member according to claim 4, wherein the valve body and the discharge portion are integrally formed.
6 . 底部に吐出孔を備える有底略筒状または略椀状の吐出部と、 当該吐出部内に配置されて、 上記吐出孔側を下流側としたときに上流側か ら液圧を受けていない状態で上記吐出孔または当該吐出孔につながる流路を 閉鎖し、 かつ上流側から液圧を受けると伸張変形して当該吐出孔または流路 を開放する、 弾性体からなる弁体と、 6. A bottomed substantially cylindrical or bowl-shaped discharge portion having a discharge hole at the bottom, and is disposed in the discharge portion, and receives the hydraulic pressure from the upstream side when the discharge hole side is the downstream side. A valve body made of an elastic body, which closes the discharge hole or the flow path leading to the discharge hole in a state where the discharge hole or the flow path is not received, and expands and deforms when the liquid pressure is received from the upstream side to open the discharge hole or the flow path;
通気フィルタを介して上記弁体よりも上流側の流路とつながる通気孔と、 を備え、  A vent that is connected to a flow path on the upstream side of the valve body through a vent filter,
上記弁体の伸張変形が上記通気フィルタの通液圧よりも小さい液圧によつ て達成されかつ上記吐出孔または上記流路の開放が、 上記通気フィルタへの 外部からの通気圧では達成されないものである吐出部材。  The expansion deformation of the valve body is achieved by a hydraulic pressure smaller than the hydraulic pressure of the ventilation filter, and the opening of the discharge hole or the flow path is not achieved by an external ventilation pressure to the ventilation filter. A discharge member.
7 . 上記弁体が上記流路内に固定される弁本体部と、 その吐出孔側先端に おける突起とを有するものであり、  7. The valve body has a valve body fixed in the flow path, and a projection at the tip of the discharge hole side.
上記弁本体部先端の突起は、 吐出孔につながる流路の内壁に設けられた凸 条にその下流側から係合して、 当該流路を閉鎖するものであり、 かつ、 上記弁本体部は、 上流側から液圧を受けると下流側に伸張変形して、 当該 弁本体部先端の突起と上記流路内壁における凸条との間に間隙を形成するも のである請求項 6記載の吐出部材。  The projection at the tip of the valve body engages with a ridge provided on the inner wall of the flow passage connected to the discharge hole from the downstream side to close the flow passage. 7. The discharge member according to claim 6, wherein when receiving the hydraulic pressure from the upstream side, it expands and deforms to the downstream side to form a gap between the projection at the tip of the valve body and the ridge on the inner wall of the flow passage. .
8 . 底部に吐出孔を備える有底略筒状または略椀状の吐出部と、 当該吐出部の外表面側から当接して、 上記吐出孔側を下流側としたときに 上流側から液圧を受けていない状態で上記吐出孔を閉鎖し、 かつ上流側から 液圧を受けると伸張変形して当該吐出孔を開放する、 弾性体からなる弁体と 通気フィルタを介して上記弁体よりも上流側の流路につながる通気孔と、 を備え、 8. A bottomed substantially cylindrical or bowl-shaped discharge part having a discharge hole at the bottom, which comes into contact with the outer surface side of the discharge part, and when the discharge hole side is the downstream side, the hydraulic pressure from the upstream side A valve body made of an elastic body, which closes the discharge hole in a state in which the discharge hole is not received, and expands and deforms when the hydraulic pressure is received from the upstream side to open the discharge hole. A vent hole connected to a flow path on the upstream side of the valve body through a ventilation filter,
当該弁体の伸張変形が上記通気フィルタの通液圧よりも小さい液圧によつ て達成されかつ上記吐出孔の開放が、 上記通気フィルタへの外部からの通気 圧では達成されないものである吐出部材。  A discharge in which the expansion deformation of the valve element is achieved by a hydraulic pressure lower than the hydraulic pressure of the ventilation filter and the opening of the discharge hole is not achieved by an external ventilation pressure to the ventilation filter. Element.
9 . 上記吐出孔は、 上記吐出部内に固定される略円盤状の弁座と、 当該弁 座を保持する吐出部内壁面とによって区画されてなるものであり、  9. The discharge hole is defined by a substantially disk-shaped valve seat fixed in the discharge portion, and a discharge portion inner wall surface holding the valve seat,
上記弁体は、 略環状の薄肉部を有するものでありかつ当該薄肉部を上記吐 出部の外表面側から上記弁座に当接させて吐出孔を閉鎖するものであり、 上記弁体の薄肉部は、 上流側から液圧を受けると下流側に伸張変形して、 当該吐出孔を開放するものである請求項 8記載の吐出部材。  The valve body has a substantially annular thin portion, and closes the discharge hole by bringing the thin portion into contact with the valve seat from the outer surface side of the discharge portion. 9. The discharge member according to claim 8, wherein the thin portion expands and deforms downstream when receiving a hydraulic pressure from the upstream side to open the discharge hole.
1 0 . 上記弁体と上記吐出部とを一体成形してなる請求項 9記載の吐出部 材。  10. The discharge member according to claim 9, wherein the valve body and the discharge portion are integrally formed.
1 1 . 底部に孔を備える有底略筒状または略椀状の吐出部と、  1. An approximately cylindrical or bowl-shaped discharge section having a hole at the bottom,
略環状の弁本体部とその先端に設けられた略環状の薄肉部とを有しかつ当 該薄肉部を上記孔から吐出部外に露出した状態で、 当該弁本体部を吐出部内 に固定してなる、 弾性体からなる弁体と、  A valve body having a substantially annular valve body and a substantially annular thin portion provided at the tip thereof, and fixing the valve body in the discharge portion in a state where the thin portion is exposed from the hole to the outside of the discharge portion. A valve body made of an elastic body,
当該吐出部内に配置されて、 上記弁体とともに吐出孔を区画してなる円柱 状の弁体支持部と、  A cylindrical valve body support portion disposed in the discharge portion and defining a discharge hole together with the valve body;
上記吐出孔側を下流側としたときに、 通気フィルタを介して上記弁体より も上流側の流路につながる通気孔と、  A vent hole connected to a flow path on the upstream side of the valve body through a vent filter when the discharge port side is a downstream side;
を備え、 With
上記弁体が、 上流側から液圧を受けていない状態でその薄肉部を弁体支持 部の外周面に当接させて上記吐出孔を閉鎖し、 かつ上流側から液圧を受ける と当該薄肉部を伸張変形させて当該吐出孔を開放するものであり、  When the valve body receives no hydraulic pressure from the upstream side, the thin portion of the valve body contacts the outer peripheral surface of the valve body support portion to close the discharge hole. Part is stretched and deformed to open the discharge hole,
上記薄肉部の伸張変形が上記通気フィルタの通液圧よりも小さい液圧によ つて達成されかつ上記吐出孔の開放が、 上記通気フィルタへの外部からの通 気圧では達成されないものである吐出部材。 A discharge member in which the expansion deformation of the thin portion is achieved by a liquid pressure lower than the liquid pressure of the ventilation filter, and the opening of the discharge hole is not achieved by an external air pressure to the ventilation filter. .
1 2. 上記弁体支持部がその円柱部分の上流側にフランジ部を有しており 上記弁体の弁本体部が、 上流側から液圧を受けていない状態で上記フラン ジ部に当接して上記流路を閉鎖するものであり、 かつ上流側から液圧を受け ると圧縮変形して上記弁体支持部との間に流路を開放するものである請求項 1 1記載の吐出部材。 1 2. The valve body support has a flange on the upstream side of the cylindrical portion, and the valve body of the valve comes into contact with the flange without receiving the hydraulic pressure from the upstream side. The discharge member according to claim 11, wherein the flow path is closed by closing the flow path, and is compressed and deformed when receiving a hydraulic pressure from an upstream side to open the flow path between the flow path and the valve element supporting portion. .
1 3 . 上記弁体と上記吐出部とを一体成形してなる請求項 1 1または 1 2 記載の吐出部材。  13. The discharge member according to claim 11, wherein the valve body and the discharge portion are integrally formed.
1 4 . 上記弁体が抗菌処理されたものである請求項 2 ~ 1 3のいずれかに 記載の吐出部材。  14. The discharge member according to any one of claims 2 to 13, wherein the valve body has been subjected to antibacterial treatment.
1 5 . 上記吐出孔が抗菌処理されたものである請求項 2〜 1 3のいずれか に記載の吐出部材。  15. The discharge member according to any one of claims 2 to 13, wherein the discharge hole has been subjected to an antibacterial treatment.
1 6 . 上記吐出孔よりも上流側、 または上記弁体による上記流路の開閉位 置よりも上流側に通液フィルタを備える請求項 2〜1 3のいずれかに記載の 吐出部材。  16. The discharge member according to any one of claims 2 to 13, further comprising a liquid passage filter upstream of the discharge hole or upstream of an opening / closing position of the flow path by the valve element.
1 7 . 請求項 1〜1 6のいずれかに記載の吐出部材を容器本体の口部に備 る容器。  17. A container provided with the discharge member according to any one of claims 1 to 16 at an opening of a container body.
1 8 . 上記吐出部材の流路の内部または上記容器本体の内部に摺動自在に 保持される内栓を備えており、 当該内栓が、 容器の未使用時に上記吐出部材 の流路の内壁に当接して当該流路を閉鎖するものである請求項 1 7記載の容  18. An inner plug that is slidably held inside the flow path of the discharge member or the inside of the container body, and the inner plug is an inner wall of the flow path of the discharge member when the container is not used. 18. The container according to claim 17, wherein the flow path is closed by contacting the flow path.
1 9 . 点眼容器である請求項 1 7または 1 8記載の容器。 19. The container according to claim 17 or 18, which is an ophthalmic container.
PCT/JP2003/009572 2002-07-31 2003-07-29 Discharge member and container provided with the same WO2004011345A1 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
EP03771397A EP1541487A1 (en) 2002-07-31 2003-07-29 Discharge member and container provided with the same
CA002493365A CA2493365A1 (en) 2002-07-31 2003-07-29 Delivery device and container provided with the same
MXPA05001236A MXPA05001236A (en) 2002-07-31 2003-07-29 Discharge member and container provided with the same.
JP2005505577A JPWO2004011345A1 (en) 2002-07-31 2003-07-29 Discharge member and container comprising the same
BR0313111-4A BR0313111A (en) 2002-07-31 2003-07-29 Shipping device and container provided with it
US10/522,800 US20060043116A1 (en) 2002-07-31 2003-07-29 Discharge member and container provided with the same
AU2003248136A AU2003248136A1 (en) 2002-07-31 2003-07-29 Discharge member and container provided with the same
HK06100075.2A HK1083210B (en) 2002-07-31 2006-01-04 Discharge member and container provided with the same

Applications Claiming Priority (8)

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JP2010115484A (en) * 2008-10-15 2010-05-27 Rexam Pharma La Verpilliere Liquid discharging device including sealing element
JP2010131370A (en) * 2008-10-15 2010-06-17 Rexam Pharma La Verpilliere Liquid distribution device including sealing element movable under effect of pressure from user
WO2010134590A1 (en) * 2009-05-22 2010-11-25 大塚製薬株式会社 Container for eye drops
WO2011099309A1 (en) * 2010-02-15 2011-08-18 Abe Shuntaro Fluid storage container and lid thereof
WO2015002110A1 (en) * 2013-07-05 2015-01-08 ロート製薬株式会社 Ophthalmic preparation container
JP2015504393A (en) * 2011-11-21 2015-02-12 アプタル ラドルフツエル ゲーエムベーハ Dispenser for delivering drug liquid
JP2015177982A (en) * 2009-09-11 2015-10-08 レグザム・エルスカール・ラ・ベルピリエール liquid dispenser device
CN106237443A (en) * 2015-12-22 2016-12-21 陈陆陆 Defecator and include its filtration infusion vessel

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FR2963326B1 (en) * 2010-07-30 2012-09-07 Rexam Healthcare La Verpillier TIP AND CONTAINER FOR DISTRIBUTING LIQUID
CN102070115B (en) * 2010-11-12 2012-07-04 余姚市特力喷雾器有限公司 Liquid distributor and container provided with same
US9346600B2 (en) 2011-10-31 2016-05-24 Yoshino Kogyosho Co., Ltd. Discharge container
FR2988015B1 (en) * 2012-03-19 2015-12-11 Rexam Healthcare La Verpillier LIQUID DISPENSING DEVICE WITH REMOVABLE CAP
JP6373734B2 (en) * 2014-11-21 2018-08-15 サーパス工業株式会社 VALVE INTEGRATED CONTAINER, LIQUID EXTRACTION DEVICE HAVING THE SAME, AND METHOD FOR PRODUCING VALVE INTEGRATED CONTAINER
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CN106864964A (en) * 2017-04-18 2017-06-20 广东海洋大学 A kind of package with fluid
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009291605A (en) * 2008-06-02 2009-12-17 Ing Erich Pfeiffer Gmbh & Co Kg Dispensing device
JP2010115484A (en) * 2008-10-15 2010-05-27 Rexam Pharma La Verpilliere Liquid discharging device including sealing element
JP2010131370A (en) * 2008-10-15 2010-06-17 Rexam Pharma La Verpilliere Liquid distribution device including sealing element movable under effect of pressure from user
US8794490B2 (en) 2008-10-15 2014-08-05 Rexam Healthcare La Verpilliere Liquid dispensing device equipped with a sealing component moveable under the effect of pressure by a user
US8783521B2 (en) 2009-05-22 2014-07-22 Otsuka Pharmaceutical Co., Ltd. Container for eye drops
JP5531013B2 (en) * 2009-05-22 2014-06-25 大塚製薬株式会社 Eye drops container
WO2010134590A1 (en) * 2009-05-22 2010-11-25 大塚製薬株式会社 Container for eye drops
JP2015177982A (en) * 2009-09-11 2015-10-08 レグザム・エルスカール・ラ・ベルピリエール liquid dispenser device
WO2011099309A1 (en) * 2010-02-15 2011-08-18 Abe Shuntaro Fluid storage container and lid thereof
JP5994112B2 (en) * 2010-02-15 2016-09-21 俊太郎 阿部 Fluid substance storage container and its lid
JP2015504393A (en) * 2011-11-21 2015-02-12 アプタル ラドルフツエル ゲーエムベーハ Dispenser for delivering drug liquid
US9833356B2 (en) 2011-11-21 2017-12-05 Aptar Radolfzell Gmbh Dispenser for dispensing pharmaceutical liquids
WO2015002110A1 (en) * 2013-07-05 2015-01-08 ロート製薬株式会社 Ophthalmic preparation container
JPWO2015002110A1 (en) * 2013-07-05 2017-02-23 ロート製薬株式会社 Eye drops container
CN106237443A (en) * 2015-12-22 2016-12-21 陈陆陆 Defecator and include its filtration infusion vessel

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BR0313111A (en) 2005-07-12
CN100390027C (en) 2008-05-28
MY140596A (en) 2009-12-31
JPWO2004011345A1 (en) 2005-11-24
HK1083210A1 (en) 2006-06-30
HK1083210B (en) 2009-02-06
EP1541487A1 (en) 2005-06-15
CA2493365A1 (en) 2004-02-05
MXPA05001236A (en) 2005-06-08
AR045969A1 (en) 2005-11-23
TW200404716A (en) 2004-04-01
CN1671601A (en) 2005-09-21
TWI294396B (en) 2008-03-11
AU2003248136A1 (en) 2004-02-16
KR20050029245A (en) 2005-03-24
US20060043116A1 (en) 2006-03-02

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