+

WO2004097030A3 - Prognostic breast cancer biomarkers - Google Patents

Prognostic breast cancer biomarkers Download PDF

Info

Publication number
WO2004097030A3
WO2004097030A3 PCT/US2004/013076 US2004013076W WO2004097030A3 WO 2004097030 A3 WO2004097030 A3 WO 2004097030A3 US 2004013076 W US2004013076 W US 2004013076W WO 2004097030 A3 WO2004097030 A3 WO 2004097030A3
Authority
WO
WIPO (PCT)
Prior art keywords
breast cancer
cancer biomarkers
mammal
level
prognostic breast
Prior art date
Application number
PCT/US2004/013076
Other languages
French (fr)
Other versions
WO2004097030A2 (en
Inventor
Jonas Bergh
Yudi Pawitan
Per Hall
Lukas C Amler
Xia Han
Fei Huang
Peter Shaw
Original Assignee
Bristol Myers Squibb Co
Karolinska Innovations Ab
Jonas Bergh
Yudi Pawitan
Per Hall
Lukas C Amler
Xia Han
Fei Huang
Peter Shaw
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co, Karolinska Innovations Ab, Jonas Bergh, Yudi Pawitan, Per Hall, Lukas C Amler, Xia Han, Fei Huang, Peter Shaw filed Critical Bristol Myers Squibb Co
Publication of WO2004097030A2 publication Critical patent/WO2004097030A2/en
Publication of WO2004097030A3 publication Critical patent/WO2004097030A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

A method of identifying a mammal at increased risk for developing breast cancer comprising the steps of obtaining a biological sample from the mammal, measuring in said biological sample the level of at least one biomarker, correlating said level of at least one biomarker with a baseline level, identifying a mammal at increased risk for developing breast cancer based on said correlation.
PCT/US2004/013076 2003-04-28 2004-04-28 Prognostic breast cancer biomarkers WO2004097030A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46608403P 2003-04-28 2003-04-28
US60/466,084 2003-04-28

Publications (2)

Publication Number Publication Date
WO2004097030A2 WO2004097030A2 (en) 2004-11-11
WO2004097030A3 true WO2004097030A3 (en) 2005-03-24

Family

ID=33418338

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/013076 WO2004097030A2 (en) 2003-04-28 2004-04-28 Prognostic breast cancer biomarkers

Country Status (1)

Country Link
WO (1) WO2004097030A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6984522B2 (en) 2000-08-03 2006-01-10 Regents Of The University Of Michigan Isolation and use of solid tumor stem cells
JP4157157B2 (en) 2005-12-14 2008-09-24 株式会社Ｊｃｌバイオアッセイ Detection and treatment for high-grade breast cancer
US20110144198A1 (en) * 2008-05-16 2011-06-16 Atlas Antibodies Ab Breast cancer prognostics
JP6407990B2 (en) * 2013-07-12 2018-10-17 ベー．エル．アー．ハー．エム．エス ゲゼルシャフト ミット ベシュレンクテル ハフツング Augrin immunoassay

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHARPENTIER ET AL.: "Effects of estrogen on global gene expression: identification of novel targets of estrogen action", CANCER RESEARCH, vol. 60, 1 November 2000 (2000-11-01), pages 5977 - 5983 *

Also Published As

Publication number Publication date
WO2004097030A2 (en) 2004-11-11

Similar Documents

Publication Publication Date Title
Bradford et al. Molecular markers of prostate cancer
WO2004099432A3 (en) Identification of biomarkers for detecting pancreatic cancer
WO2004012588A3 (en) Use of biomarkers for detecting ovarian cancer
WO2007035690A3 (en) Methods for diagnosing pancreatic cancer
WO2007025044A8 (en) Biomarkers and methods for determining sensitivity to epidermal growth factor receptor modulators
WO2009006323A3 (en) Methods and marker combinations for screening for predisposition to lung cancer
WO2005098446A3 (en) Biomarkers for ovarian cancer
WO2006023769A3 (en) Determining data quality and/or segmental aneusomy using a computer system
WO2007030949A3 (en) Methods of diagnosing ovarian cancer and kits therefor
WO2008095152A3 (en) Methods and materials for identifying the origin of a carcinoma of unknown primary origin
WO2008008284A3 (en) Cancer biomarkers and methods of use threof
WO2004030511A3 (en) Prostate cancer biomarkers
WO2006128192A3 (en) Use of free circulating dna for diagnosis, prognosis, and treatment of cancer
WO2010033371A3 (en) Molecular markers for lung and colorectal carcinomas
CA2701341A1 (en) Method of assessing colorectal cancer from a stool sample by use of the marker combination calprotectin and hemoglobin/haptoglobin complex
WO2007056523A3 (en) Methods for diagnosing and monitoring the progression of cancer
WO2010009074A3 (en) Method for predicting and detecting tumor metastasis
WO2008140463A3 (en) Biomarker panels for assessing radiation injury and exposure
WO2006102526A3 (en) Identification of biomarkers by serum protein profiling
WO2005094332A3 (en) Biomarkers and methods for determining sensitivity to epidermal growth factor receptor modulators in non-small cell lung cancer
WO2005100999A3 (en) Functional immunohistochemical cell cycle analysis as a prognostic indicator for cancer
WO2003057014A3 (en) Biomarkers for detecting ovarian cancer
WO2008131261A3 (en) Peptide biomarkers of cardiovascular disease
WO2003091695A3 (en) Identification of biomarkers for detecting prostate cancer
WO2005067667A3 (en) Biomarkers and methods for determining sensitivity to epidermal growth factor receptor modulators

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
122 Ep: pct application non-entry in european phase
点击 这是indexloc提供的php浏览器服务，不要输入任何密码和下载