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WO2004093876A3 - Composition containing berberine or a derivative thereof and an antimicrobial agent or an antibiotic agent, and their use for treating oral pathogens and other disorders - Google Patents

Composition containing berberine or a derivative thereof and an antimicrobial agent or an antibiotic agent, and their use for treating oral pathogens and other disorders Download PDF

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Publication number
WO2004093876A3
WO2004093876A3 PCT/US2004/008616 US2004008616W WO2004093876A3 WO 2004093876 A3 WO2004093876 A3 WO 2004093876A3 US 2004008616 W US2004008616 W US 2004008616W WO 2004093876 A3 WO2004093876 A3 WO 2004093876A3
Authority
WO
WIPO (PCT)
Prior art keywords
disorders
derivative
agent
composition containing
treating oral
Prior art date
Application number
PCT/US2004/008616
Other languages
French (fr)
Other versions
WO2004093876A2 (en
Inventor
Christine D Wu
Douglas Kinghorn
Sara Kate Roberts
Original Assignee
Univ Illinois
Christine D Wu
Douglas Kinghorn
Sara Kate Roberts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Illinois, Christine D Wu, Douglas Kinghorn, Sara Kate Roberts filed Critical Univ Illinois
Priority to US10/551,639 priority Critical patent/US20070098649A1/en
Publication of WO2004093876A2 publication Critical patent/WO2004093876A2/en
Publication of WO2004093876A3 publication Critical patent/WO2004093876A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4741—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having oxygen as a ring hetero atom, e.g. tubocuraran derivatives, noscapine, bicuculline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A composition and method of controlling oral and other human pathogens is disclosed. The composition and method utilize an antimicrobial or antibiotic and a berberine as active agents to treat mammals, including humans.
PCT/US2004/008616 2003-04-03 2004-03-22 Composition containing berberine or a derivative thereof and an antimicrobial agent or an antibiotic agent, and their use for treating oral pathogens and other disorders WO2004093876A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US10/551,639 US20070098649A1 (en) 2004-03-22 2004-03-22 Method and composition for controlling oral pathogens

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46018703P 2003-04-03 2003-04-03
US60/460,187 2003-04-03

Publications (2)

Publication Number Publication Date
WO2004093876A2 WO2004093876A2 (en) 2004-11-04
WO2004093876A3 true WO2004093876A3 (en) 2005-10-13

Family

ID=33310718

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/008616 WO2004093876A2 (en) 2003-04-03 2004-03-22 Composition containing berberine or a derivative thereof and an antimicrobial agent or an antibiotic agent, and their use for treating oral pathogens and other disorders

Country Status (1)

Country Link
WO (1) WO2004093876A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1787627A1 (en) * 2005-11-17 2007-05-23 3M Innovative Properties Company Anti-microbial dental impression material
AU2010268647B2 (en) * 2009-06-30 2015-01-15 Derman Biomedicine Co. Ltd. Compositions containing berberine or analogs thereof for treating rosacea or red face related skin disorders
CN102079765B (en) * 2010-12-15 2013-03-20 西南大学 9-O-glucoside-berberine salt, and preparation method and application thereof
CN105497028A (en) * 2015-12-15 2016-04-20 上海壹志医药科技有限公司 Medicinal application of berberrubine
WO2017143361A1 (en) * 2016-02-18 2017-08-24 Drabinsky Michael Earl Treatment for spirochete borne illness
AU2018241231B2 (en) * 2017-03-28 2024-06-06 IRP Health Pty Ltd Berberine alkaloids in the prevention and/or treatment of intestinal disease
EP3777856B1 (en) * 2018-04-13 2022-02-09 Institute Of Materia Medica, Chinese Academy Of Medical Sciences Hydrophilic berberine-type derivative and application thereof in preparing drug

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5741138A (en) * 1996-08-12 1998-04-21 The Procter & Gamble Company Oral compositions
WO1998044926A1 (en) * 1997-04-04 1998-10-15 Optiva Corp. Antimicrobial compositions
US6248309B1 (en) * 1997-04-04 2001-06-19 Optiva Corporation Gums containing antimicrobial agents
WO2002091848A1 (en) * 2001-05-15 2002-11-21 The Procter & Gamble Company Confectionery compositions

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5741138A (en) * 1996-08-12 1998-04-21 The Procter & Gamble Company Oral compositions
WO1998044926A1 (en) * 1997-04-04 1998-10-15 Optiva Corp. Antimicrobial compositions
US6248309B1 (en) * 1997-04-04 2001-06-19 Optiva Corporation Gums containing antimicrobial agents
WO2002091848A1 (en) * 2001-05-15 2002-11-21 The Procter & Gamble Company Confectionery compositions

Also Published As

Publication number Publication date
WO2004093876A2 (en) 2004-11-04

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