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WO2004087105A8 - Formulations associant du platine et des fluoropyrimidines - Google Patents

Formulations associant du platine et des fluoropyrimidines

Info

Publication number
WO2004087105A8
WO2004087105A8 PCT/CA2004/000508 CA2004000508W WO2004087105A8 WO 2004087105 A8 WO2004087105 A8 WO 2004087105A8 CA 2004000508 W CA2004000508 W CA 2004000508W WO 2004087105 A8 WO2004087105 A8 WO 2004087105A8
Authority
WO
WIPO (PCT)
Prior art keywords
fluoropyrimidines
combination formulations
platinum agents
platinum
agents
Prior art date
Application number
PCT/CA2004/000508
Other languages
English (en)
Other versions
WO2004087105A1 (fr
Inventor
Lawrence Mayer
Marcel Bally
Murray Webb
Paul Tardi
Clifford Shew
Original Assignee
Celator Technologies Inc
Lawrence Mayer
Marcel Bally
Murray Webb
Paul Tardi
Clifford Shew
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celator Technologies Inc, Lawrence Mayer, Marcel Bally, Murray Webb, Paul Tardi, Clifford Shew filed Critical Celator Technologies Inc
Publication of WO2004087105A1 publication Critical patent/WO2004087105A1/fr
Publication of WO2004087105A8 publication Critical patent/WO2004087105A8/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'invention concerne des compositions qui comprennent des liposomes auxquels sont associés, de manière stable, du platine et un antimétabolite. Ces compositions permettent d'obtenir des effets thérapeutiques améliorés lorsque les combinaisons de ces médicaments sont administrées.
PCT/CA2004/000508 2003-04-02 2004-04-02 Formulations associant du platine et des fluoropyrimidines WO2004087105A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46025103P 2003-04-02 2003-04-02
US60/460,251 2003-04-02

Publications (2)

Publication Number Publication Date
WO2004087105A1 WO2004087105A1 (fr) 2004-10-14
WO2004087105A8 true WO2004087105A8 (fr) 2005-03-10

Family

ID=33131918

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CA2004/000508 WO2004087105A1 (fr) 2003-04-02 2004-04-02 Formulations associant du platine et des fluoropyrimidines

Country Status (1)

Country Link
WO (1) WO2004087105A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2574767C (fr) 2004-07-19 2015-02-17 Celator Pharmaceuticals, Inc. Produits de synthese particulaires destines a la liberation d'agents actifs
EP1796689A4 (fr) * 2004-09-20 2009-01-14 British Columbia Cancer Agency Gemcitabine libre ou encapsulee dans des liposomes seule ou en association avec de l'idarubicine libre ou encapsulee dans des liposomes
CA2587741A1 (fr) * 2004-11-18 2006-05-26 Celator Pharmaceuticals, Inc. Procede pour charger des agents multiples dans des vehicules d'administration
FR2891843A1 (fr) * 2005-10-06 2007-04-13 Erytech Pharma Soc Par Actions Erythrocytes contenant du 5-fluorouracile
CA2630538A1 (fr) * 2005-11-30 2007-06-07 Celator Pharmaceuticals, Inc. Administration localisee de combinaisons de medicaments
WO2009097011A1 (fr) 2007-08-17 2009-08-06 Celator Pharmaceuticals, Inc. Préparations améliorées de médicaments au platine
EP2123258A1 (fr) * 2008-05-23 2009-11-25 Liplasome Pharma A/S Liposomes pour l'administration de médicaments
WO2021072407A1 (fr) * 2019-10-10 2021-04-15 The University Of North Carolina At Chapel Hill Complexes de système d'administration comprenant un précipité d'un agent actif et procédés d'utilisation
US11980636B2 (en) 2020-11-18 2024-05-14 Jazz Pharmaceuticals Ireland Limited Treatment of hematological disorders

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69531722T2 (de) * 1994-11-11 2004-07-01 Debiopharm S.A. Karzinostatische Zusammensetzungen, welche Cis-Oxaliplatin und eine oder mehrere andere verträgliche Karzinostatika enthalten
DE19724796A1 (de) * 1997-06-06 1998-12-10 Max Delbrueck Centrum Mittel zur Antitumortherapie
US6511676B1 (en) * 1999-11-05 2003-01-28 Teni Boulikas Therapy for human cancers using cisplatin and other drugs or genes encapsulated into liposomes
WO2001082892A2 (fr) * 2000-05-02 2001-11-08 Pharmacept Gmbh Liposomes a base de principes actifs
GB0011903D0 (en) * 2000-05-18 2000-07-05 Astrazeneca Ab Combination chemotherapy
RU2284184C2 (ru) * 2001-03-06 2006-09-27 Бристол-Маерс Сквибб Компани Способ лечения рака
AU2002331480B2 (en) * 2001-10-03 2007-10-25 Celator Pharmaceuticals, Inc. Compositions for delivery of drug combinations

Also Published As

Publication number Publication date
WO2004087105A1 (fr) 2004-10-14

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