WO2004082572A3 - Diagnostics et therapies pour les maladies associees au recepteur 87 couple a la proteine g (gpr87) - Google Patents
Diagnostics et therapies pour les maladies associees au recepteur 87 couple a la proteine g (gpr87) Download PDFInfo
- Publication number
- WO2004082572A3 WO2004082572A3 PCT/EP2004/002273 EP2004002273W WO2004082572A3 WO 2004082572 A3 WO2004082572 A3 WO 2004082572A3 EP 2004002273 W EP2004002273 W EP 2004002273W WO 2004082572 A3 WO2004082572 A3 WO 2004082572A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- disorders
- gpr87
- diseases
- therapeutics
- diagnostics
- Prior art date
Links
- 102100038407 G-protein coupled receptor 87 Human genes 0.000 title abstract 2
- 101710107772 G-protein coupled receptor 87 Proteins 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 2
- 208000018522 Gastrointestinal disease Diseases 0.000 abstract 2
- 101001033052 Homo sapiens G-protein coupled receptor 87 Proteins 0.000 abstract 2
- 208000012902 Nervous system disease Diseases 0.000 abstract 2
- 208000025966 Neurological disease Diseases 0.000 abstract 2
- 230000002496 gastric effect Effects 0.000 abstract 2
- 208000014951 hematologic disease Diseases 0.000 abstract 2
- 208000027866 inflammatory disease Diseases 0.000 abstract 2
- 208000019423 liver disease Diseases 0.000 abstract 2
- 208000023504 respiratory system disease Diseases 0.000 abstract 2
- 208000014001 urinary system disease Diseases 0.000 abstract 2
- 238000003556 assay Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 102000047704 human GPR87 Human genes 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
- G01N33/5735—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes co-enzymes or co-factors, e.g. NAD, ATP
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Hematology (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Urology & Nephrology (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Genetics & Genomics (AREA)
- General Physics & Mathematics (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Cette invention concerne un récepteur GPR87 humain qui est associé aux troubles cardio-vasculaires, aux maladies gastro-intestinales et hépatiques, aux maladies inflammatoires, aux troubles hématologiques, aux maladies respiratoires, aux troubles neurologiques et aux troubles urologiques. Cette invention concerne également des dosages pour l'identification de composés utiles dans le traitement ou la prévention des troubles cardio-vasculaires, des maladies gastro-intestinales et hépatiques, des maladies inflammatoires, des troubles hématologiques, des maladies respiratoires, des troubles neurologiques et des troubles urologiques. Cette invention se rapporte également à des composés qui se fixent au récepteur GPR87 et/ou qui activent ou inhibent l'activité du récepteur GPR87, ainsi qu'à des compositions pharmaceutiques comprenant de tels composés.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03006105 | 2003-03-18 | ||
| EP03006105.5 | 2003-03-18 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2004082572A2 WO2004082572A2 (fr) | 2004-09-30 |
| WO2004082572A3 true WO2004082572A3 (fr) | 2005-01-06 |
Family
ID=33016835
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/EP2004/002273 WO2004082572A2 (fr) | 2003-03-18 | 2004-03-05 | Diagnostics et therapies pour les maladies associees au recepteur 87 couple a la proteine g (gpr87) |
Country Status (1)
| Country | Link |
|---|---|
| WO (1) | WO2004082572A2 (fr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1900377A1 (fr) * | 2006-09-12 | 2008-03-19 | Boehringer Ingelheim International GmbH | Inhibiteurs de GPR87 pour le traitement de cancer |
| JP5800299B2 (ja) * | 2009-02-20 | 2015-10-28 | 国立大学法人 東京大学 | 新規モノクローナル抗体、並びにその使用 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001044474A1 (fr) * | 1999-12-16 | 2001-06-21 | Millennium Pharmaceuticals, Inc. | Recepteur 2871, recepteur couple a la proteine g et ses procedes d'utilisation |
| WO2002092624A2 (fr) * | 2001-05-16 | 2002-11-21 | Paradigm Therapeutics Limited | Recepteur |
| US20030017539A1 (en) * | 1998-06-02 | 2003-01-23 | Millennium Pharmaceuticals, Inc. | Novel nucleic acid sequences encoding G-protein coupled receptors |
-
2004
- 2004-03-05 WO PCT/EP2004/002273 patent/WO2004082572A2/fr active Application Filing
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030017539A1 (en) * | 1998-06-02 | 2003-01-23 | Millennium Pharmaceuticals, Inc. | Novel nucleic acid sequences encoding G-protein coupled receptors |
| WO2001044474A1 (fr) * | 1999-12-16 | 2001-06-21 | Millennium Pharmaceuticals, Inc. | Recepteur 2871, recepteur couple a la proteine g et ses procedes d'utilisation |
| WO2002092624A2 (fr) * | 2001-05-16 | 2002-11-21 | Paradigm Therapeutics Limited | Recepteur |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004082572A2 (fr) | 2004-09-30 |
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